Conserved Protein Domain Family
COG2433

?
COG2433: COG2433 
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]
Statistics
?
PSSM-Id: 441980
Aligned: 57 rows
Threshold Bit Score: 515.562
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_055408125   1 MIGVDIEPGCSsg----aRCYSVAVVDDG-KLVaKYESVPLYRLIRLIWEYRPDILAIDNIYELASS--ERELVKITSML 73 
BAA80599      10 VMGVDIVSGEPgs---rsARYAAVILGESgRLLeKHESISLARLIRVAWSRQPDILAVDNVFELGRS--ERDVGRVASML 84 
ADM28332       7 VLGIDIVRGSPlsr-ttpPYYSAVIIDEN-GLVyEAPEIPLKSIIRLILEYKVNRIGLDNIYEIAPT--SKSIARILGMF 82 
WP_083756963  14 VVAVDLEPGSPpg---ikGKFHLVLVDCDgKVI-IDKRVDIKKLIRILWEFRPKLIAVDNLTELGEN--QRELIKFLNLI 87 
WP_048058719  32 VIGVDIQPGSSpns-rrqPLYSAVVLRNG-EIIaSFEDVELYRLLRLVLEYHVDIIAVDNIYELAPS--ENELRRIFELL 107
WP_013143452   9 VAGIDILPGYSirssnrqPHYALVLVDLDgNIIdSYEDVSFARLLRLVWEHKPSIMAIDNVFELAEN--VDELRKIVDML 86 
WP_048812855  17 YMGVDIESGSPlss-tnrAKYSVVIIDQSlKLIaKHQSVPLATIIRLAWEYRPRSIASDNVMELSLDgsTESIARLLSLL 95 
WP_014025699  16 VIGFDVQPGGL---------FAVVGIDSAeKLVfKQEDVTLARLIRLVWEYRPRLLACDNIFELSED--ESLLRKVLSML 84 
WP_015233086   8 YMGIDIESGSPlsk--enHKFFVIIIDNDlKIVnKIRDITLSSLIRLAWEWKPKAIAIDNVFEIAKD--EKSLSKILSLL 83 
WP_020962662   6 ILGLDVLPGSSpqg--asLLFAAVLVVDG-KVVeKWREVNLDKIVEIVSDRNVDALALDNVYELAAN--IDELSRFLKRF 80 
WP_055408125  74 PpDLNIVQPTRlpDGSLVDLRRLAKLAGLDTgsGKLSPARTAYLAALLASMGYGSRIRFVEEKTRIVIAKSRRLKHGGMS 153
BAA80599      85 PpKTRLVQVTLe-GGRLASLREVAERYGIRVe-KKLTPTATAYLLAVLALEGAGTPVSVLEEKTLVTVSRARSGSSGGWS 162
ADM28332      83 PaDVEIYQVTIe-DKNFVSLVNQALKIGLDIt-KKPRPLQTAYICALLALNGIGTIIRGKERKTKIIISKARSVGSGGSS 160
WP_083756963  88 PpETEVVQVTRv-DGEFVDLRELLKVHGMRFtsEKLTPRETALALAFLALKGVGTKVKVFEEKTKIIVTKGRTPRAGGSS 166
WP_048058719 108 PgNVKVVQVTGp-PNDARDVNSVARELGIDT--VIETPLKTAYINALAAYRGIGYEVRLFAEKTRIVVTKGRSVTQGGMS 184
WP_013143452  87 PpQTKLVQVTGw-GPEAVNVKTIARKIGLEVh-GKLSPLRTAYLSALIASRGEGVVVKLLEEKTKIIVTRGRSVGHGGMS 164
WP_048812855  96 PpGTKLVQATAt-EDGLVDVLEAARRAGIDVasSKLSPMRTAFIVAAVVAKGGGQSVGFSREKTYIVVSRGRNTKSGGWS 174
WP_014025699  85 PdETEVVQVTRnpDGSFVDLRSLALLAGIRVe-GKLSPSKTAYLVAVLAKRGFGSRVAFTEEKTKIIIARARHGSSGGMS 163
WP_015233086  84 PpQTQLVQVTIn-DGKFADIKEIAKQINLEIdqGKLTPSKTAYLAAVIALKGKGTKISFSNEKTQIIVSKGRWSKSGGMS 162
WP_020962662  81 PrSPRIIQVTFi-DGETVSIEALCALTGICS--GKLDPLQTAEVCALLAYNGVGAEALVFEEETLIRVGRGRVPGQGGMS 157
WP_055408125 154 SPRYQRRVRSAVLRAVKDVKRILDRHRLDYDLMFRKSGGGLDSAVFIVYAPRSRLNgiIKPHEDSDVRIEIQPVYSSRIV 233
BAA80599     163 QARYQRRVRAAISQAVSRIRESLDRAGLDYDLNYRRSEGGIESATFIVYAPREKLEgvVRRREGPDYTVRIKPVARSRIL 242
ADM28332     161 ANRFARGMRTAILRATREIKYLLDKASLNYDLVFRRGSGGLDSAVFIVYSDYKTVRkvIKPFEGNDVRIIIKPEYT-TIE 239
WP_083756963 167 MNRFVRATRNAVIETVNEIKSTLEKEGLDYDLFIRKSDGSIDSATFIVYAPRKSLEglVKPVSSSAVRVKVRPVVTRKFM 246
WP_048058719 185 RDRFLRCIRASIAQATKEIKRILDENKLDYDMVIKRSKGGLEKSVFIVYAPRESLYglIKPLKYKNVKIIIKPYASRK-S 263
WP_013143452 165 YDRYRRSIRAGILNVTKTVKKILDQNGFDYDLVFRKSNGGLEKSIFTVYAPRDKLYglIKPFKNKSVRLIVKPVYTNKVS 244
WP_048812855 175 QARYQRRIRASVKIAADKVKEALDNANIDYDVFYKTSEGGLDSAIFIVYAPREKLIgiVRPHRGIDYSIRIETKYEGELV 254
WP_014025699 164 QARYQRGVKASILRATRIIKKLLDKHGFDYDLIFRKSGYGLESAVFIVYAPRSALYgiIRRFKGRDLRIEIRPVYTGRVV 243
WP_015233086 163 QNRYQRRIRASVNIAANKIKDLLERSGIDYDMFVKKGEGGIDSAIFTVYTSREKLYgiVRPHKGIDYSIAIKSIYDGKIL 242
WP_020962662 158 RERFKRNIELQVKRKVREISEALRKNSLDYDLFIRKSGEGLTGATFIVYAPREKLNglVKNEDGHELFVRIEPVGREKIE 237
WP_055408125 234 FETeASDql---sqTKPYIIVGIDPGISTGVAAVDLNGRPIFALSRRGVDRSEVIELITRHGIPVLIATDVRPAPEFVRK 310
BAA80599     243 TLP-DAPe------RSSPVIVGIDPGITTGLAVLDINGRLLHAESSKSLDRSRVTEIVYGLGRPVIVAVDVADPPETAKK 315
ADM28332     240 FVN-EKDs------RKRPIIVGIDPGMETGIAIIDLSLQNVFLTSSKELDRMEIINLIYNIGIPALIATDKNPPPESVKK 312
WP_083756963 247 FED-EEQr------TKELLVVGIDPGIKTGLAILNVEGEVLFLGSFKNADRGELVSLINKFGLPIIIATDTSPPSHTAKK 319
WP_048058719 264 IEP-VSDq------ARKPVIVGVDPGMSIGVSVLTLDGEPVLITSMKSPDRDEIVNLISRIGKPVVVATDVSKPPETVVK 336
WP_013143452 245 FENaGAEk------PRKGLIIGIDPGISTGIAVIDLDGTPLFLHSSKNFDRGEILNIVSSMGEAVIVATDVSHPPELVKK 318
WP_048812855 255 FGG-ATSk------PSRPLIVGVDAGMTTGLAVLDLEGRVLHLGSYKELDRGKIVSIVSSLGKPVIVTTDVADPPELIRK 327
WP_014025699 244 FES-IRDqq----aPRRYLIVGVDPGIVTGVAAVDLHGNPVFVYSRKGLDRAEIIELVKRHGEPVLIATDVTPPPETVKK 318
WP_015233086 243 FGN-NLDk------PDRPIIVGIDPGITTGIAIIDLEGNVLYLDSKKEMDRGDIISLIYSYGKPILLAVDVDIIPDMVKK 315
WP_020962662 238 FQP-LGAkvsykplTEKYLIVGIDPGMSTGYAVLDLNGRVLSLETGRLLGRGDLMRRLYSIGKPVVIATDVNPPPAYVRK 316
WP_055408125 311 LAAAMGVPVYEPPASLSVEEKRSIVEEytrrypeLrRVTDAHVRDALAAAVKALHIHESKMRQIESYTARlglDIDVDAV 390
BAA80599     316 LAAQWGAMLYTPPADLTTSEKWGLARRvl----gS-SVEDTHVRDAAAAAYKAYLALESKLRSVERTIEKmgiDVDVERV 390
ADM28332     313 IASTIGVPLYIPSHSLSIEEKERLVEIvkn-rldI-DIKTVHERDALAAALKAYKTYEKKFIELERKLMDldiDIDIDEM 390
WP_083756963 320 LAATLNAELYYPKNSLSVKEKERIAEEyra--rgV-NVEDSHQRDALAAAHKALNAIKGKIEKVENYLERiglDVDRDRV 396
WP_048058719 337 LASMLNAVLYVPEQDITIDEKNRIAREyse-kyvV-NIPDSHTRDALAAAVKAYNNYKATIEEVKSKLANm-kKVDRYQL 413
WP_013143452 319 TASILNAQLYLPPRDMANDEKHDLINKllkkypwL-DIQDTHERDALAAAYKAYLSISEKIKQALLKIEDidlYINKENI 397
WP_048812855 328 LAAQLGAQLYLPNYNMSVAEKEYLASRata-nseL-KPKTPHERDSLAAAYRAFIEYHNKLSQVEAYASKlefDIDIDEL 405
WP_014025699 319 LASSLGVPLYTPPYSLTVDEKQELVASiss-rlsI-SRLNAHERDALAAALRAYREYSSKFRQIESTVAKypaEISIDNL 396
WP_015233086 316 LASQINAEIYVPREDMLVVDKSSLALKatg----geNPDTTHERDALASAYKAFLNYKSKLSQVESYVEKidiDLDVEKI 391
WP_020962662 317 IAATLGCQLFVPSRSLSIDEKRRLALEaae-argL-KVKTSHERDSLAAAYKAFLYYRPLFEEVEKEGEKydlPVPIDEA 394
WP_055408125 391 KADVI-KGATIAEAVERAIHAALNDVGLRSYLVKsvr-rsqVEStpEPQQAENEDQVSRLRMEIERLRAENIALRRRLRE 468
BAA80599     391 KIDVI-RGATLAEALERAIEEELGDGEPEAPRAErgarqhqEEA--AGDGGSVYKEMSALREMLEALRIENSSLKRRLEE 467
ADM28332     391 KLLLL-QGKTINEILEHVIETYIESTLNGygeer--arynyIVN--AIEDEEKDRKIRNLENRVKELLKEREVLRNRIHE 465
WP_083756963 397 RLSVLkEGRSIADVVEEEIGELIKEEGGEEDVYP-------TAQ--QPKRNDLEGGGLKSALKLAYLEAENVSLKLKIKE 467
WP_048058719 414 IAEII-RGKPFSEVLEEHFKRSIPKIPPVVE---------------EKMKPTTTPVCEKLSEKVNTLEALVRKLLDEIER 477
WP_013143452 398 KINIV-RGKSIAEAIEEEIEKLLNKKNRSNQITKdk----tLEN--QNTVEDHSRKIKKLINEIKRLRAYIARLENKLKE 470
WP_048812855 406 KADVV-KGATLAEAVEKQIAKLLGNIDEKYESMN------------VINRQQVQQPCAD-SSKVELLEAQKMSLEKQLED 471
WP_014025699 397 KATVL-KGLTIAEALEAEIERILVEEPPKPVKSVrh----tQKE--QQHQDVNNETISKLQEELEAARARIQVLEKKLQE 469
WP_015233086 392 KADVI-RGITIADAIDKQINEMLNLNNEEYKEEN------------NNNCNPDKQPENELISKIQKLEAEKITLENKVNE 458
WP_020962662 395 KLLVI-RGKPVSIAIQEAMRKHVGLRLPLERFDK-------FSS--GTEIEKMQGELEFLKRVVEELVHENTLLRHELRK 464
WP_055408125 469 VDEQLKRLEAEYRLLQIEYRESLEKDREINKLTNEVKLLRSEIEKLRNEAKTLYAELSELQDALFLVASGRALPAPRLHE 548
BAA80599     468 MEAEVMMLKAQLERARARAKSDHGIRREAEMMRERVRKLERRLEESAMMVEELKGELEELRRAVELLGRGTHLLAVEVDR 547
ADM28332     466 LEQKLSKLEYESKFKGMPINI---DDIELNKLRERIKQLQNTIDTLLKEIEENKKRTQFLETMINKLVLSEYVGIPKLRI 542
WP_083756963 468 LEATIEKLNLELNLIRRQIEDE--VERKVSSIKESYSQLTRKVEELQRINEELSSLLEKAGEAALKVERGEAFVALYLDD 545
WP_048058719 478 KDLYIKDLELELKLTRSRKPGIEDYERKISALQNELEALRRKIEDKDNVIRELYEKLLQLEEHVVKLGRGDLVMIPKVST 557
WP_013143452 471 KDRLIEDLVLELKYVKKSTINNDENSRKINLLIYENKNLRKKLEEMEEKLVETRRKYIELSKLLEEIIRDKEIAVPHIPN 550
WP_048812855 472 LRQRLFYEERELYLAKKQLKAELLKDDEIRALKGRVSELESSLAKLQGEQEHLQEEIQSLRRVLVDVASGRLVVARRVSE 551
WP_014025699 470 CIERSKHLENEARLAKLEAASK--AEEKLVEYKYRIESLQHELEKLRKHVEELTVSQRRMLELMRSVAMGVKALVPAVKG 547
WP_015233086 459 LIKSLAISENEVRSVKQKLKTELLKDEEIKKLKNDVSRLNSLVNELEENINIANEKNNLFKNILMKILNNEMIIIKRLQS 538
WP_020962662 465 AEERAQRSEETLKRLLQLRELGKRLNPEFSKMEARIEMLQSEINSLKSVLENTILEEKRLKETMYSVVLGEKIAVLKLSR 544
WP_055408125 549 LD------NESMNMLAKLVen--hgRIIAVMDTVNPVQWNRHGAIVSKLLL----AVLVPRE--LLDRRGVIEAYSVPVL 614
BAA80599     548 LT------LKTVREAAAamr---ggRLILVLRGGDTFTWDAVEELAKAGVE----AVVADHP--SSPAANALKSRRVPVI 612
ADM28332     543 LS------VSGIMDVIDlv----raTKVILLEEP-IIEPDALKLVKELN------CIIILQKc-EENLKSFLLEHEIPTA 604
WP_083756963 546 ITftskfpEHEIEELP---------TRAILANKVEALNEDFIEKILENN------IMLFASEi-NEKTKKELEDRGIPVI 609
WP_048058719 558 VR------REGgl-----------vNRGVYMEKVLEISSELKNILTSGR------GFIV-----SPVVAVDPLKERIPVV 609
WP_013143452 551 LS------YNSVRKIINTSktkntnHSIIYVDEIMPLDNDTIQILRKYKV-----AILTEKDy-----GQLYVDLKVPVI 614
WP_048812855 552 LR------SSQLKRSEEQLgpi-saNEVVIVDNVTAFDSNAVEYLSKAGVK----AILVNDA--DSPLANAAKNRRIAPL 618
WP_014025699 548 LN------KTSLRRLMNDPly--wtTRVIYLHEPGILDESVLVQLVENELV----AILAPETi-PQNIVEIIKANNIPVI 614
WP_015233086 539 LK------MNNIKKVEDIYgkl-keGDVILIEDQGSFENDAINYIIKKNIL----AIIVNRE--DTTLSELLKKKGIPVL 605
WP_020962662 545 LLd-----KSGLR------------AQYLFV-DKELPEDYLFRVLGEIKPPsanlYVFFRNQheLQRVKGKLPIGTIPLS 606
WP_055408125 615 PL-EDYEIKTLNGLVLLDEKVIADAYYRLSEIEAARRra----ekRRLGLEDVKKMFEEYRAKRMKLL 677
BAA80599     613 PI-SEVQVLRLGGYVLVSSEVLRLAEEMRAEWRR-----------RREASVDIMRIVEEYRRSSRRg- 667
ADM28332     605 CNlD--KISEINSIVFTSKLDLDSKISEALKEVNLYRekl--rklRYIDSKRLLEIIDEYRKQLLNGS 668
WP_083756963 610 TA----SGEVYGRYAVLPIDLKDEWNERMEKLKSM----------RQMQVEDLEKLLQEYRASRWK-- 661
WP_048058719 610 KP-E--IIYDLGDYVIVEKEVIEKANELWRKIDELI---------ELERHERILRMIEEYQRSRKNS- 664
WP_013143452 615 KV-K--DAKFYDKYAFIKKDVLSLVEKQWREIEEII---------AEEQYERVIKLVAEYQEKRKKSS 670
WP_048812855 619 RV-NEYAIIQVAGLYFVSSKVISDAMEFIAKLKS-----------QESSDAALLSLLNEYRAMRGKGS 674
WP_014025699 615 LL-PPDRVIVKEDIAIVDTEVLEEAILEKLRIDEELRkrstqennLLLDADSLRRLVEAYRRERYATE 681
WP_015233086 606 NK-NDYNIVDIDIFTFAPSTILKDASMKNKELKK-----------SNVEEIDLRNIIDQYRKNKI--- 658
WP_020962662 607 ID-WVNGVEDIGDFVVLPIEEIEKAVNRQS---------------EDVEKEKLRRLLVDYREERRRSM 658
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap