Conserved Protein Domain Family
PLN03122

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PLN03122: PLN03122 
Poly [ADP-ribose] polymerase; Provisional
Statistics
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PSSM-Id: 178669
Aligned: 9 rows
Threshold Bit Score: 1312.48
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
79517236    2 KVHETRSHAHMSgDEQ-KGNLRKH------------------K-AEGKLPESEQSQKKAKPENDDGRSVNGAG----DAA 57 
225464980  15 KVHETRPQAHAN-AEEeKAGGKKQ------------------K-AENKTHEAEQAQKKAKPEKEDKDNGQKNGksaaEIA 74 
224105065   4 KVHETRSQAHAP-SDEsRIMTRKQ------------------KvGQSKAHEGEQSPKK-KAKNGKDQNDSTNGksedNIA 63 
255565595   3 KVHETRSQTHGPaADEgKVMTRKQ------------------K-AENKGHEGEQSPKK---AKNENDSSHANEktktDIS 60 
168021393   1 ---------MTTaTREtRGKARQDesyepepdgpvhegkrqrVvVGSSPARGTRSGGKAAKSTKQDAHTEELNssaeDTV 71 
115446483   1 MVHETRSRTLAAsQEEgKAAPKKQkteskeqeggqqapsknkKtADNEEHDGEQEPSKNKKLKAEESDLNGKA----TAV 76 
297808239   2 KVHETRSHAHMSgDEQkKGNLRKH------------------K-AEGKLPEAEQSQKKAKSENDNGRSVNGAG----DAA 58 
302754394     --------------------------------------------------------------------------------    
302803329   1 ---------------MsRVGTRSA------------------------EVRGKQAMDDEKQLKKQKTGGGGDAksreQDV 41 
79517236   58 SEYNEFCKAVEENLSIDQIKEVLEINGQDCSAPEETLLAQCQDLLFYGALAKCPLCG-----GTLICDNeKRFVCGGEIS 132
225464980  75 KEFEQFCKATSQHLSIKQMREILEANEQDHSGSDDAVVPRCQDMMFYGALEKCPACD-----NTFECTG-DNYVCTGAFS 148
224105065  64 KEYEEFCKAIEEHLSVEQMREILDMNDKYSSSGSD-------DLLFFGPLDKCPLCS-----SNLEFDG-KRCSCKGFYS 130
255565595  61 KEFEEFSRAIREHLSVSQMREILEMNDQDSSGSDGAVITKCQDLLLLGPLGKCPLCD-----CTLEFDG-KRYSCNGFYS 134
168021393  72 EQFQEFVDKLKDECSIEDVRAIAVENGLNSLLPDNMLLHGVADQLFYGPLQTCPLCEshgthAALICDG-HQYKCSGFIS 150
115446483  77 KEFSEFCKAIREHLTIEDMRKILQGNEQDASGSEDAVVPRCEDVMFYGPLDKCPVCG-----GQLECKG-LKYNCTGTHS 150
297808239  59 SEYNEFCKAVEENLSVDQIKEVLEINGQDCSAPEETLLAQCQDLLFYGALEKCPLCG-----GNLICDNeKRFICGGEIS 133
302754394   1 ------------------------------------------DQMMYGPLEPCPSCG-----GALKFAV-HEYTCTGYIS 32 
302803329  42 KNFHEFVEKLKSNVSEEEARAILSENAQEMDSSIS-VYEHCADQMMYGPLEPCPSCG-----GALKFAV-HEYTCTGYIS 114
79517236  133 EWCSCVFSTKDPPRKEEPVKIPDSVMNSAISDLIKKHQDPKSRPKRELG-----SADKPFVGMMISLMGRLTRTHQYWKK 207
225464980 149 EWSSCTYSTRDPVRRKEPVKLPDSVRESSAFELIKNHQEQGNFPRRNLN-----PTGKPFTGMLICLSGRLSRTHHYWRT 223
224105065 131 EWSSCTFKTRTPPRKEEPLKLPDSVLSSSVAELLKKHQDPSRRPCQ--G-----APIKPLAGIVVSLSGRLSRTHQYWKR 203
255565595 135 EWSSCTFKTRSPPRKEEPLKFPDSVLKSPIADLLKKHQDPKNRPRQELG-----APGKPFAGMIISLSGRLSRTHQYWKK 209
168021393 151 EWTMCNYTAPSAERTNGCLKLPKKLKNEFLKQFEKSH-DASKNPKRVLA-----SGEKPFLGMTIVLSGRLSRKQGARRA 224
115446483 151 EWACCSFSTNNPSRRGGPIKVPDDVKNDFVRKWLKQQ-EGNKYPKRNL------DDEGIFSGMMIALSGRMSRSHGYFKE 223
297808239 134 EWCSCVYSTKDPPRKEEPVKIPDSVMNSAISDLIKKHQDPKSRPKRELG-----SADKPFAGMMISLMGRLTRTHQYWKK 208
302754394  33 EWSKCGFSTKNVPRKKEPLKIPKQLKNDYITKRPVRHTEDSAKP----------APGKPFSGMHILLAGRTKRPQYKLRG 102
302803329 115 EWSKCGFSTKNVPRKKEPLKIPKQLKNDYITKWEQEH-DTEKRPVRHTEdsakpAPGKPFSGMHILLAGRTKRPQYKLRG 193
79517236  208 KIERNGGKVSNTV-QGVTCLVVSPAERE-RGGTSKMVEAMEQGLPVVSEAWLIDSVEKHEAQPLEAYDVVSDLSVEGKGI 285
225464980 224 KIEEHGGKDANSV-LGATCLVVSPAERE-RGGSSKVVEAMERGIPVVREAWLSDSIEKQEAQPLEAYDVVSDLSVEGKGI 301
224105065 204 EIEKHGGKVSSSF-KGITCLVVSPAERE-RGGSTKLADALEAGIPVVREDWLLDSIEKQEPQPMEAYDVVSDLSVEGKGI 281
255565595 210 TIEKYGGKVSNSV-IGVTCLVVSPAERE-RGGSSKLSEAMERNIPVAREEWLLDSIEKQEPLPLEAYDVVSDLAVEGKGI 287
168021393 225 DIEKHGGKVANAIkPGVTCVIADARDASgGGGSTKSADAISLNIPVVREEWITDCIKQKEQLPLEKYDMAAEFPGE-RDV 303
115446483 224 QIMKHGGKVNNSV-IGVTCVVASPAERH-QGGSGGFAEALERGTPVVSENWIIDSVQKKEKQPLAAYDIASDVVPEGRGL 301
297808239 209 KIERNGGKVSNTV-QGVTCLVVSPAERE-RGGTSKMVEAMEQGLPVVSEAWLIDSVEKHEAQPLEAYDVVSDLSVEGKGI 286
302754394 103 DFEKHGGKVAHALkEGITCLVVAESDLS-SGVYAKIGDARSKNIPVVKESWLQDCLSKNEVLDFAPYLFGAQAEGDKRAA 181
302803329 194 DFEKHGGKVAHALkEGITCLVVAESDLS-SGVYAKIGDARSKNIPVVKESWLQDCLSKNEVLDFAPYLFGAQAEGDKRAA 272
79517236  286 PWDK------QDPSEEAIESFSAELKMYGKRGVYMDTKLQERGGKIFEKDGLLYNCAFSICDLGKGRNEYCIMQLVTVPD 359
225464980 302 PWDK------QDPSEEALESISAEIKLYGKRGVYKDSKLQEQGGKIFEKDGILYNCAFSICDQGRGVNDYCILQLIIVPE 375
224105065 282 PWDK------QDPSEEALESISAELKLYGKRGVYKDTRMQERGGQIFEKDGILYNCAFSLCDLGRGLNEYCIMQLITVPD 355
255565595 288 PWDK------QETSEEALESISAELKLYGKRGVHKDSKLQERDGEIFEKDGILYNCAFSLCDMGREINDYCILQLINVPE 361
168021393 304 PWDK------MSPQAEAALSLMAEVKLVGKRGVYKDTELEEEGGKIFENKDIIYNCAFSI---------YAIMQLIEMPN 368
115446483 302 PLGN------LDPTEEAIETLAAELKLAGKRAVHKDSKLEKDGGHIYEKDGIIYNCAFSVCDLGGDINQLCIMQLIMVPE 375
297808239 287 PWDK------QDPSEEAIESLSAELKMYGKRGVYMDTKLQERGGKILEKDGLLYNCAFSICDLGKGRNEYCIMQLITVPE 360
302754394 182 K---------KQQVDQGPVVRFLQIKLAGKKYVHKDSELDKEGGRVFEHEGIVYNCAFSICDQTSGLNHCAAQQLVQVPD 252
302803329 273 KKQQvdqgvaADQNVDSSTYLTDEIKLAGKKYVHKDSELDKEGGRVFEHEGIVYNCAFSICDQTSGLNHCAAQQLVQVPD 352
79517236  360 SNLNMYFKRGKVGDDPNAEERLEEWED-EEAAIKEFARLFEEIAGNEFEPWEREKKIQKKPHKFFPIDMDDGIEVRSGAL 438
225464980 376 NQLHLYYKKGRVGDDTRAEERVEEWQN-VDAAVKEFVRLFEELTGNEFEPWEREKKFQKKLLKFYPIDMDDGVDVRYGGL 454
224105065 356 SNLHSYYKKGKVGDNTNAEERLEEWEN-VDNAIKEFVRLFVELTGNEFEPWEREKKFEKKRLCFYPIDMDDGMDVRHGGL 434
255565595 362 SNLHLYYKKGRVGDDPGADERLEEWED-VDNAVKEFVKIFEEITGNEFEPWEREKKFEKKRLKFYPIDMDDGVEVRQGGL 440
168021393 369 KAVYLYYKKGRVGDRLHNTERLEEMDS-TRQAMREFVKLFETLTGNPFEPWEREKKFEKKPMKFFPVDMNSGVDARAGGL 447
115446483 376 NHLHLYYKKGPIGHDQMAEERVEDFGSrFNDAIKEFVRLFEEVTGNEFEPWEREKKFKKKCMKMYPLDMDDGVDVRHGGV 455
297808239 361 SNLNMYFKRGKVGDDPNSEERLEEWED-EDAAIKEFARLFEEMTGNEFEPWEREKKIQKKPHKFFPIDMDDGIEVRSGAL 439
302754394 253 GTLYFYHKRGRLATGVPVNERMDEQTD-VNKAIHNFAALFKEITGNEFEAWEREKKFTKKRSKFYPVDMDDVCDARAGGL 331
302803329 353 GTLYFYHKRGRLATGVPVNERMDEQTD-VNKAIHNFAALFKEITGNEFEAWEREKKFTKKRSKFYPVDMDDVCDARAGGL 431
79517236  439 GLRQLGIASAHCKLDSFVANFIKVLCGQEIYNYALMELGLDPPDLPMGMLTDIHLKRCEEVLLEFVEKVKTTKETGQKAE 518
225464980 455 GLRQQGVAVAHCKLEPLVANFMKVLCSQEIYRYAMMEMGLDSPDLPMGMLSNIHLKRCEEVLLNFIETVKSIKEMDIKAK 534
224105065 435 GLRQLGVAAAHSSLEPKIAYLMKILCSQEIYKYAMMEMGLDSPDVPMGMLSDLHLERCEEVLLQFVEAVKSMKETGQKAE 514
255565595 441 GLRQLGAAAAHSKLEPQLAYFMKILCSQEIYRYALMEMGLDPPELPMGMLSDLHLKRCEEVLLQFVEAVKSMKGTGQKAE 520
168021393 448 GVHQLGTAAAHTKMNSRVAQDLKVLMSQEVYRFAMTEMAIDAPDLPSGNLTEFHLERCTDVLQQFAAYLREPEEDELKHE 527
115446483 456 ALRQLGAAAAHCKLDPSVTFIMKQLCSQEIYRYALTEMGHDVPDLPIGMLTDLHLKRGEETLLEWKQDVESAPESGPAAD 535
297808239 440 GLRQLGVASAHCKLDSFVANFIKVLCGQEIYKYALMELGLDPPDLPMGMLTDVHLKRCEEVLLEFVDKVKTTKETGQKAE 519
302754394 332 QDQQLGVVAVHCKLDPKVARFCKCLFSQAVYRHAMFEMGINSPELPLGSLSEFHFKRCEECLLEFADFLQKESDS-KKHE 410
302803329 432 QDQQLGVVAVHCKLDPKVARFCKCLFSQAVYRHAMFEMGINSPELPLGSLSEFHFKRCEECLLEFADFLRKESDS-KKHE 510
79517236  519 AMWADFSSRWFSLMHSTRPMRLHDVNELADHAASAFETVRDINTASRLIGDMRG-DTLDDPLSDRYKKLGCKISVVDKES 597
225464980 535 ATWSDFSQRWFTLLHSTRPFIFRDHQEIADHAAAALEIVRDITVASHLVGDLTG-STLDDPLFDRYKKLGCSISPLEKDT 613
224105065 515 AVWSDYSQRCSTLLHSTRPFVFRDYQDLADHGAAAFETIRDINMASRLVGDMFG-STLDDPLSDRYKKLGCSVSALEKDS 593
255565595 521 AVWSDYSQRWFTLMHSTRPLILRDYDELADNVAAAFETVRDINVASRLIGDMSG-STLDDPLSDRYKKLGCSISPVGKET 599
168021393 528 RMCLDFSNKWWSLVHTTRPFVIKDIDQVAQMAAPTLEALKAISVASQLIGNLKDeSTLDDPLADRYAKLGCQITPLDHDS 607
115446483 536 AFWMEISNKWFTLFPTTRPYTMKGYEQIADNVASGLETVRDINVASRLIGDVFG-STLDDPLSQCYKKLGCSINRVVEDS 614
297808239 520 AMWADFSSRWFSLLHSTRPMRLHDVHELADHAASAFETVRDINTASRLIGDMRG-DTLDDPLSDRYNKLGCKISVVDKES 598
302754394 411 QMCLDFSNKWFSLVPSTHPTVISDIAHLTELGASVLESLKAISVASHIIGDMTG-DTLDDPLSDRYAKLNSTMTCVDKES 489
302803329 511 QMCLDFSNKWFSLVPSTHPTVISDIAHLTELGASVLESLKAISVASHIIGDMTG-DTLDDPLSDRYAKLNSTMTCVDKES 589
79517236  598 EDYKMVVKYLETTYEPVKVSDVEYGVSVQNVFAVESDAIPSLDDIKKLPNKVLLWC------------------------ 653
225464980 614 DDYRMILKYLEKTYEPVKVGEISYGVSVDNIFAVEPSACPSHDEMKKLPSKVLLWC------------------------ 669
224105065 594 DDYKMIVKYLDTTYEPVRVGDIDYGVSVENIFSVEPSACPSLDEIKKLPNKVLLWC------------------------ 649
255565595 600 DDYKMIVNYLERTYEPIRVGDIDYGVSVENIFAVESSAHPSLDEIKKLPNKVLLWC------------------------ 655
168021393 608 EDYKMISNYLAKTIAPVKFMDSEYSVNLQEACLIDSAATPSLKDIKKMSNKQLLWCgmvlvswlspvgclgddncahvsy 687
115446483 615 EDYKMILKYLEKTYEPVKVGDVVYSATVERIYAVESSALPSYDEIKKLPNKVLLWC------------------------ 670
297808239 599 EDYKMIVKYLETTYEPVKVSDVEYGVSVQNVFAVESNAIPSLDDIKKLPNKVLLWC------------------------ 654
302754394 490 DDYKMVQKYLEKTYEPVKYDDVSVSIVMEELFMVESSAGPSFEEVDNLKNKVLLWC------------------------ 545
302803329 590 DDYKMVQKYLEKTYEPVKYDDVSVSIVMEELFMVESSAGPSFEEVDKLKNKVLLWC------------------------ 645
79517236  654 ---------------------------GSRSSNLLRHIYKGFLPAVCSLPVPGYMFGRAIVCSDAAAEAARYGFTAVDRP 706
225464980 670 ---------------------------GTRSSNLMRYLNKGFLPAICSLPVPGYMFGRAIVCSDAAAEAARYGFTAVDRP 722
224105065 650 ---------------------------GTRSSNLLRHLQKGFLPSVCSLPVPGYMFGKAIVCSDAAAEAARYGFTSVERP 702
255565595 656 ---------------------------GTRSSNLLRHLQKGFLPAACSLPVPGYMFGKAIVCSDAAAEAARYGFTAVDRP 708
168021393 688 fqnhwiftcdyttleensrdnhieihtGTRTCNLLACMKVGMPPASIEAPASGYMFGEGWYCSDSAARAAQFGFTAVDRP 767
115446483 671 ---------------------------GTRSSNLLRHLRDGFVPAVCHIPVPGYMFGKAIVCSDAAAEAALYGFTAVDRP 723
297808239 655 ---------------------------GSWSSNLLRHIYKGFLPAVCSLPVPGYMFGRAIVCSDAAAEAARYGFTAVDRP 707
302754394 546 ---------------------------GTRTCNLISTLAQGMQPAIYNAPVPGYMFGKGLYCTDASCKAASYAFTGVDRP 598
302803329 646 ---------------------------GTRTCNLISTLAQGMQPAIYNAPVPGYMFGKGLYCTDASCKAASYAFTGVDRP 698
79517236  707 EGFLVLAVASLGEEVTEFTSPP--EDTKTLEDKKIGVKGLGRKKTEESEHFMWRDDIKVPCGRLVPSEHKDSPLEYNEYA 784
225464980 723 EGFLVLAVVSLGDQVNEYKNPP--EETKSLEEKQLGGKGLGRKKPDENEHTVWEDDVKVPCGHLIPSEYKDSPLEYNEYC 800
224105065 703 EGFLVLAVASLGDQIIEVKSPP--EDTKSLEEKKRGVKGLGKKKTDESEHFIWKDDIKVPCGRLIPSEHRDSPLEYNEYA 780
255565595 709 EGFLILAVASLGDEVTEVSSTP--EDTKSFEEKKIGVKGLGRKKTDESEHFMWRDDIKVPCGRLMPSENKDGPLEYNEYA 786
168021393 768 EGYLILAVVGLGDEILELTKPE--EDVSQYKKKKVAIKGLGKMTTDPDGYIKFEEDITVPCGPLIP-GKEDSPLDFNEFC 844
115446483 724 EGYLVLAVASLGKEIQEITGTPgsEDVKRMEEKKMGVKGVGRKTTDPSEHFTWRDGVTVPCGKLVPSTNKDGPLEYNEYA 803
297808239 708 EGFLVLAVASLGEEVTEFTNPP--EDTKTLEEKKIGVKGLGRKKTEESEHFMWRDDIKVPCGRLVPSEHKDSPLEYNEYA 785
302754394 599 EGFLMLAVVGLGDNVLELPKPE--EDVAKYEREKVAIKALGKKLPDSSEYFKWKNNITVPCGALKSSGRDDCTLDYNEYV 676
302803329 699 EGFLMLAVVGLGDNVLELPKPE--EDVAKYEREKVAIKALGKKLPDSSEYFKWKNNITVPCGALKSSGRDDCTLDYNEYV 776
79517236  785 VYDPKQTSIRFLVEVKYEEKGTEIVDVE 812
225464980 801 VYDPKQVSIRFLVGVKYEERDVEMDTAE 828
224105065 781 VYDPKQTRIRFLVEVKYEEMGAELDTTE 808
255565595 787 VYDPKQTSIRFLVGIKYEEKDAVMDTAE 814
168021393 845 VYDSMQVKPHYLLRVRYELVA------- 865
115446483 804 VYDPKQVSIAFLVGVKYEEQNMEVVPDE 831
297808239 786 VYDPKQTSIRFLVEVKYEEKGTEIVDVE 813
302754394 677 VYDPKQVKLQYIVQVRYEEK-------- 696
302803329 777 VYDPKQVKLQYIVQVRYEEK-------- 796
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