Conserved Protein Domain Family
Stathmin

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pfam00836: Stathmin 
Stathmin family
The Stathmin family of proteins play an important role in the regulation of the microtubule cytoskeleton. They regulate microtubule dynamics by promoting depolymerization of microtubules and/or preventing polymerization of tubulin heterodimers.
Statistics
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PSSM-Id: 459956
Aligned: 23 rows
Threshold Bit Score: 104.352
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001339376  38 EDMEVKSLNKRASGQAFEVILKSPTDPSp-eRPQTLAlPPQRKEPSLG--ELQRRLEAAEARRRSQEKQVLKQLAEKRER 114
XP_002589936  41 ADMQVKQLDK--SGKAFEVVIKPPSKDA---SEVKLS-SPPRSPTCLDakTIQEKLEKAEERRKSMEAETLKKLAKEREH 114
XP_002130876   6 EDIKVKEICKGNSGEAFEVILKLPGQNGdgvASPLKSlTP-KKEVSMD--EIKMKLQAAEERRKAVQEAKVTQQKAEEEK 82 
ESO00020       3 EGTELK--RECGGGVAFEVIIKPASSDV-------APpSPSKDRPAISqeDIDRKLKEAEERRVQLESQRLQAVLKEKDK 73 
EKC36039      22 LQKPHFWLQKSTGGVAYDYILKPAADNA-----PKISsPPKDKPLTHD--EIFEKLQKAEARRQSLEAQKLEFVAKEKQR 94 
XP_784642      1 MPSEV----KTPGGMAFECILDENKKPD----TSKRPaTPPKSKSTTSldEINAKLQEAERRRRSVETQMLEKLAEENAR 72 
EEB17440      15 IHTEVRCQESSKGGMSFELRLADPVVLT----PPKRPlSPPKIVSVAD---IEEKLKAAEDRRKSLTASQVAILSAKLAK 87 
Q9VMH3        54 ITTEIRCQEKSRGGLSYEVILAEPAPNV---AVPKRPvTPGKNVSVEE---IEQKLKAAEERRISLEAKKMADISTKLAK 127 fruit fly
Q16KX5        53 ITTEIRCQEKSKGGLCYEVILAEPAVNV---TLPKLPvTPGKAVSAEE---IEEKLKAAEERRLSLEAKKMADWSAKMAK 126 yellow fever mo...
EFA03170      12 DPTEVRCQEKTRGGLRYEVILSEPEVKA---TPPKKAvSPKNSMSVQD---IEDKLKAAEERRQQLESNKIAALAAKMQK 85 
XP_001339376 115 EKEVLTKAQEVNNNYSKKTEEKLNHKMEMITENRMARLNALKQRLREKEIHAEEVRKNKEL 175
XP_002589936 115 QTEVLSKAAEVEAAFAKKAQEELKKKQELYEQNQQAQRQAKIERLKEMEKHAEEVRRNKKE 175
XP_002130876  83 ILKAKQKKAEVNDSFSQWAEQHLKKQMCQYQENHIAQLEAKIKKFKALNMKPEEMKEKVQR 143
ESO00020      74 VVEVNLKNKDIEEAFSKEVEKKLADKLVASEELKKAQEAAKLEKLKEHERHVQEVRKKKQA 134
EKC36039      95 MQEALMKSQKEEEEKAKAAQAKLRRSMEITKENRELQIMSLQEKLREHLAKVQEVCKNSES 155
XP_784642     73 ILEAQAKVAEKNNNFKMEAKKQYVEKMTKVEINQQAQQEAFNLKLQEKKNHI-KVVQERNM 132
EEB17440      88 IEDARKKYDEQEKQFIQQTEEALKQKIASYEENRESHINDLKAKLKEHLEGVEKTRLNLEQ 148
Q9VMH3       128 VEEATRKKDEITNEFITQTKEQLESKMELHVEKREAIISDMKEKLKIHAQDIEKTRETLEQ 188 fruit fly
Q16KX5       127 IEEATRKKDEMDKIFKTHAKELLDTKMEQYEEKREQQISEIKEKLKMHAAEIEKTRHSLEH 187 yellow fever mosquito
EFA03170      86 IEEASRKKDEQTSQFISATRDALEQKMENHTEKREAYITDLKTKLKDHIENVEKTRLSIEQ 146
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