2O1X


Conserved Protein Domain Family
Dxs

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COG1154: Dxs 
Deoxyxylulose-5-phosphate synthase [Coenzyme transport and metabolism, Lipid transport and metabolism]
Deoxyxylulose-5-phosphate synthase is part of the Pathway/BioSystem: Pyridoxal phosphate biosynthesis
Statistics
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PSSM-Id: 440768
Aligned: 644 rows
Threshold Bit Score: 751.459
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2O1X_A         9 DTPLLDQIHGPKDLKRLSREQLPALTEELRGEIVRVCSRGGLHLASSLGAVDIITALHYVLDSP--RDRILFDVGHQAYA 86 
WP_013628927   2 EYELLPMISSPKDLKTLSEPQLERLAAEIREALCQIVERKPAHFASNLGVVELCLALHLVFDFE--KDRLIWDTGHQIYP 79 
WP_013564655   2 TSALLARIAAPADLHTLTEAQLDQLACEMREELIRVVSRRSAHFASNLGVVELCLALHLEFDFT--RDRLIWDTGHQVYP 79 
WP_015250556   2 SSTMLPKIESPADLHSLSEKDLERLAAEMREELIGIVGRRSAHFASNLGVVELCLALHLAFDFS--QDRLIWDTGHQIYP 79 
WP_075092753   2 EFELLPLIGSPEELRSLNDAQLEQVAVEIREKLCEIVSDRPAHFASNLGVVELCLALHLTFDFS--KDRLIWDTGHQIYP 79 
WP_083713057   4 PDSLLARIGAPEDLKKLSDKELDQLADEMRGELIGVVGRRAAHFASNLGVVELCLALHLTFDFT--EDRLIWDTGHQIYP 81 
WP_077026594   2 PFEILSELKSPKQLRDLDDQQQNQLASEIREALLTIVSDRAAHFASNLGVVELCIALHSVFDFS--KDRLIWDTGHQVYP 79 
WP_085756066   8 KQTLLDAINSPEDIRQLSIPQLGELAEQIRDFIVSTVSDTGGHLASNLGTIEATLAMHYVFDFS--KDYLLWDVGHQCYA 85 
WP_010047482   2 TTQLLPQIQSPADLHALSDEQLQQLTHEIRDELIRVLTTRPAHFASNLGVVELTVALHLAFDFSkdKDRLIWDTGHQIYP 81 
WP_099325262   1 MNNILDSVEFPEDLKKLNPEDLPKLASEIRSFIVDVISKNPGHLSSNLGVVELTMALHYCFDFR--KDRIVWDVGHQAYV 78 
2O1X_A        87 HKILTGRRDQMADIKKEGGISGFTKVSESEHDAITVGHASTSLTNALGMALARDAQG--KD-FHVAAVIGDGSLTGGMAL 163
WP_013628927  80 HKLITGRFSRFETIRDRGGLMGFPNPNESPYDLFMTGHAGASVSTVLGLQAADDLLF--EDgRKSVAVIGDGALPSGVVF 157
WP_013564655  80 HKLITGRASQLETIRSKGGLMGYPNPAESDFDLFMTGHAGCAASTALGLKLGDELMGr-PD-TFAVAVVGDGALPSGIVF 157
WP_015250556  80 HKLITGRAAELHSIRTKGGLMGYPNPAESLYDLFMTGHAGCAPSTALGLKAGDDLVGh-PE-RHSVAVIGDGAFPSGIVF 157
WP_075092753  80 HKLITGRFHEFNTIRRKGGLMGYPHPGESDYDLFMTGHAGASVSTALGLRAGDDLVHpeEG-RRSVAVIGDGALPSGVVF 158
WP_083713057  82 HKLITGRAEELHTIRTKGGLMGYPNPAESPFDLFMTGHAGCAPSTALGLKLGDEIMGr-PD-RHSVAVIGDGALPSGIVF 159
WP_077026594  80 HKLVTGRFPEFQSIRTRGGLMGYPNPVESDYDLFVTGHAGSSVSTVLGLKTADDLLFsdED-RKSVAVIGDGALPSGIVF 158
WP_085756066  86 HKIITGRKDKFSLLRKEGGVSGFPEPSESSYDRFRVGHAGTSIATGLGIGWGLMDQG--RD-DKVVSFVGDGSIVNGASF 162
WP_010047482  82 QKLITGRYEQFHTIRTKGGLMGFPHPGESEYDLFMTGHAGCSVSTASGLKAGDELMGr-PD-NHAVAVIGDGAFPSGIVF 159
WP_099325262  79 HKILTGRKTHFSILRQYKGLSGFPDKNESVYDPFTCGHSGDAISSALGLSCADEIIG--YK-RSIVVVVGDGGIGAGMSL 155
2O1X_A       164 AALNTIGDMGRKMLIVLNDNEMSISENVGAMNKFMRGLQVQKWFQEGEGAGKKAVEa---vSKPLADFMSRAKNSTRHFF 240
WP_013628927 158 EAMNNAVGLKKDILVILNDNQMGICPRVGGLATYLDNARVAPFYNGLKRDIAWALNkvpmvGNSVEHALSNMKDAVKTLL 237
WP_013564655 158 EAMNNAGGLKRPFLLILNDNKMSICPRVGGLANYLDRIRMAPTYNDLNRRVKDWIRrlplvGGFAERTMQTVKDAVKASV 237
WP_015250556 158 EALNNAGGLRKKFLVVLNDNQMSICPRVGGLGYYFDKARMTPMYSDWNRRVRKLLPsiplvGDQADRWLQQMKDAIKASV 237
WP_075092753 159 EAFNNAAELDKNFLVILNDNKMGICPRVGGLAKYLDHARVAPFYNGLKKDISWLLNkvpfvGEPTKEMLGGIKDAVRNFV 238
WP_083713057 160 EAFNHAGGSQSKLLVILNDNKMSICPPVGGIANALDRARMSTTYNDWNKRVRSVLPtiplvGETADRWLQQFKDAVKASL 239
WP_077026594 159 EAMNNAAGLNKDLLVVLNDNKMGICPRVGGVASYLDKARVAPFYNGLKRDVSWLLNklpvvGEPVEHMLGQFKEALKTFF 238
WP_085756066 163 EALNNLPGLPRQMLVVLNDNNMSIDVTRGAVAKIFSKIRLNSTYEELNRTAKTIIEhmpliGKQVEGAVQRFKKAIRMQQ 242
WP_010047482 160 EALNNIGGMGQNTLVILNDNKMSICPRTGGVAKYFDQCRMTGLYQGGKRRINQILDhvpliGETARASLEAMRDGLKAWI 239
WP_099325262 156 EALNHAGDIKKNLLVVLNDNEMSISNTVGAVSKYLNKIRTMPIYADIRKELRGLIKilpvlGKPMEKTLEHLVELVKIGA 235
2O1X_A       241 DPAsvNPFAAMGVRYVGPVDGHNVQELVWLLERLVDLDGPTILHIVTTKGKGLSYAEADPIYWHGPAKFDPATG-E---- 315
WP_013628927 238 HGG--RLFEEMGFRYIGPVDGHDLDALRKYLEMVKDIKGPTLLHVFTEKGKGFKPASEDPVTFHSPSPFDRTDDgD---- 311
WP_013564655 238 NGG--MLFEELGFTYLGPIDGHHLPTLRAYLQKVKKLNGPVLLHVLTDKGRGFAPAEADPVKFHAPQPFQKVEKaGgtvs 315
WP_015250556 238 HGG--MLFEELGFTYIGPIDGHDLKTLRTYLEKVKAMDGPVLLHVLTDKGHGFEPAVKDPVKYHAPAPFQRVED-G---- 310
WP_075092753 239 HGG--RLFEELGFRYIGPVDGHDLKSLREYLEMVKDVKGPVLLHVFTEKGRGFKFAEKDPVAFHTPAPFCRSDDdEe--g 314
WP_083713057 240 HHG--MLFEELGFTYLGPIDGHDLKSVRTYLEKVKAMEGPILLHVLTNKGHGFEPAVKDPVKFHAPAPFMKAED-G---- 312
WP_077026594 239 HGG--MLFEEMGFRYIGPVDGHDIQSLQRYLEMVKEVKGPVLLHVFTEKGYGFEPAQKDPVKFHTPAPFCRDENnE---- 312
WP_085756066 243 SAG--QLFESLNLSYFGPVNGHDIGSLIELFTALKDLDHPAVLHIYTNKGKGYKPAGDNPSKYHSTGPFY-ING-E---- 314
WP_010047482 240 KDG--MLFEELGFRYFGPVDGHDLPALRKILKDLKGQKGPILLHVLTNKGHGVPQAAEDPVTYHTPPVFAEVGPdRa--- 314
WP_099325262 236 TPG--RIFEDLGFNYFGPIDGHDFKVLTETINDIKHLNGPVLLHVITEKGRGFEPAYQNPTQFHSSGKFKLSEG-K---- 308
2O1X_A       316 YV-----PSSAYSWSAAFGEAVTEW-AKTDPRTFVVTPAMREGSGLVEFSRVHPHRYLDVGIAEEVAVTTAAGMALQGMR 389
WP_013628927 312 AIpr--pKGSVPAYTNIASKTIYDA-MERDSKVVVMTAAMCAGNDLGRIRDDFPQRFFDTGICEAHAVAFAAGMAKSGMK 388
WP_013564655 316 VAplkanAPSSKAFTDAVSSALFEA-MARDPRVSVLTAAMCEGNKLQKIRDTYPERFFDVGICESHAVAFAAGMAKAGAR 394
WP_015250556 311 IIpl--kTSTHKAFTDAVSAALFAA-MERDPKVAVLTAAMCEGNKLQKIREVFPDRFFDTGICESHAVAFAAGMAKAGAR 387
WP_075092753 315 VQfl--kKPASRAYTDAVSDAIHAA-MERDARVCVLTAAMCEGNKLQKIRADFPNRFFDVGICEGHAVAFAGGMAKAGMR 391
WP_083713057 313 IVpl--kISTSQTYTDAVSAALFDV-CRDDSRVVVLTAAMCEGNKLQKLRTSFPKQFFDVGICESHAVALAAGMAKAGAR 389
WP_077026594 313 IVpv--sADKSVAYTNIAADAIHQA-MQADEKVCVLTAAMCAGNKLNKIRDEFPDRFFDTGICEGHAVAFAGGMAKSGMR 389
WP_085756066 315 SKk-----SGKKSYTKVLGEALCEIaADKNSGVAAITAAMPEGTGLNIFRDHFPDKYYDVGICESAAVDMAAGMAKTGLT 389
WP_010047482 315 IVsf--kKGGARAYTDAVSVALHRA-MQDDPTIAVMTAAMCQGNKLEKVREDFPDRFHDVGICESHAVAFAAGMAKSGAN 391
WP_099325262 309 IEke-vqDAGKISYTKVFSDALVEF-SKTNPSIVGITAAMPDGTGMISFGEKFPDRYFDVGICEQHAVGLANGLSTEKLK 386
2O1X_A       390 PVVAIYSTFLQRAYDQVLHDVAIEHLNVTFCIDRAGIVGADGATHNGVFDLSFLRSIPGVRIGLPKDAAELRGMLKYAQT 469
WP_013628927 389 PIVDIYSTFLQRSFDHIFQEVALQNLPVVFCMDRAGLCGPDGPTHHGVFDNTYMRTFPNITVMAPGDTADLQAMIPFSLE 468
WP_013564655 395 PVVDIYSTFLQRSYDQIFQEVSLQNLPVLFTLDRAGLVGSDGPTHHGTYDIAWMRIFPHMVVMAPGDGGEVAAMIDFGLS 474
WP_015250556 388 PVVDIYSTFLQRSYDQIFQEVSLQNLPVIFTLDRAGLVGSDGPTHHGSYDLAYMRMFPNMVVMAPGDEKDVAPMIEFALG 467
WP_075092753 392 PIVDIYSTFLQRSYDHIFQEVALQNLPVTFCLDRAGVVGADGPTHHGAYDNTYMRSFPNIVVMAPGDEQDVVPMLDLALS 471
WP_083713057 390 PVVDIYSTFLQRAYDQIFQEVALQNLPVVFCLDRAGLVGADGPTHHGSYDIASLRIFPNMVVMAPGDQRDVGPMLDFALA 469
WP_077026594 390 PIVDIYSTFLQRSFDQIFQEVALQNLPVVFCMDRAGLCGPDGPTHHGVFDNSYMRIFPNMVVMAPGDELDVPLMLDFALS 469
WP_085756066 390 PFVCLYSTFLQRAFDQIAHDIAQQNLHVVFCIDRAGVVGDDGPTHHGMLDIGMLRMLPNMILCAPASGEEMRSALMYAEK 469
WP_010047482 392 PVVDIYSTFLQRSFDQIFQEVCLQNLHVTFLMDRAGLTGPDGPTHHGVFDVPYMRLFPNMVSMAPGDEADVAPMVKFALQ 471
WP_099325262 387 PVVAIYSTFLQRAYDQVFHDICLQKNPVVFVMDRSGVVGNDGPTHNGVFDIAYLRNLPGIVLMSPKDGSELRAMLKIAID 466
2O1X_A       470 HDGPFAIRYPRGNTAQ-V-P-AGTWPDLKWGEWERLKGG-DDVVILAGGKALDYALKAAEDLP-----GVGVVNARFVKP 540
WP_013628927 469 HDGPISIRYPKANAVT-V-ErENEVAPIELGKSEVLQWG-TDGMIVCFGALLPECVKAAEKLQkd-glDVGVINARFLRP 544
WP_013564655 475 HNGPVSIRYPKTALEV-V-Er-LHPPRIELGKAEVLDRQ-PDGTFLVFGAQVPTALRAAEILRrdhglRVGVVNARFVKP 550
WP_015250556 468 HNAPVSIRYPKANLET-I-Er--EAQPIELGQAEVLEWE-TDGIFLACGTLVSSCLRAAERLRqqyglRIGVVNARFAKP 542
WP_075092753 472 HPGPTSIRYPKTNVAT-V-Gr--TSTQIELGRSEVYRWG-EDGMFVAFGVQFIDCVKAAELLKae-giDVGVINARFLRP 545
WP_083713057 470 HTSPTAIRYPRANLHA-V-Er--EVQPIELGQAEIIDWE-TDGMIVACGAQLGACLQAAERLHkryglQVGVINARFIKP 544
WP_077026594 470 IDSPSSIRYPKTNAET-V-Er--SVAPIEMGKSEVMSWG-EDGNILACGVLLPRAIEAAEKLRge-glDVGVVNARFVKP 543
WP_085756066 470 TKAPVGIRYPRDVLPEnLsDiESLSEDFETGKSVLLSAGdADVVLVSYGAVLTEVVEAAKILEqs-glRCDVLNARFAKP 548
WP_010047482 472 HTGPISVRYPKANLET-M-ErAEPVAPIELGKAEVIEWG-EDGCFVAFGTLLSNCVAAAKKLKae-giHMGVVNARFVKP 547
WP_099325262 467 SDEIIAIRYPKENIPD-E-KiDLECKPFGIGEAEILREG-KDGVLLAYGCMVQRCLQAAEQLSgk-gvEATVVNARYAKP 542
2O1X_A       541 LDEEMLREVGGRARALITVEDNTVVGGFGGAVLEALNSMNLH-P-TVRVLGIPDEFQEHATAESVHARAGIDAPAI-RTV 617
WP_013628927 545 LDTDVILKAVRECGFVVTVEENTLCGGFGSTVLEAANDAGLPtN-NIKRLGIPDRFIEHGNRSELLGELGLDAVGFiREI 623
WP_013564655 551 LDEAVILQTLTESPFVITVEEGCLMGGFGAAVLELANAHRIDtR-HVTRLGLPDRFIMHAERDEQLAEVGLDVEGLvRAA 629
WP_015250556 543 LDKTVVLKAVEECGFVLTVEEGCLAGGFGSAVLEVASDAGLStA-NVRRLGLPDHYILHAERDEQLAEVGLDVDGIaRAA 621
WP_075092753 546 LDTEVIFKAIESSGFVITVEESTLNGGFGSAVLEAANDAGLDtR-NVRRVGLPDRFVDVAERAEQLAEVGLDIAGLaKTA 624
WP_083713057 545 LDSRTICKAIEEAAFVLTVEEGCLPGGFGSAVLEAANDAGLPtA-HVRRLGLPDRFILHAERDEQLAEVGLDVDGVtRAA 623
WP_077026594 544 VDEDVIRRAI-ETGFVITIEENAICGGFGSAVLEAANRMGEPtD-RIKVLAIPDEFVEHGPRGELLADLGLDAAGLcKAA 621
WP_085756066 549 IDPQI-VELAREGKMLFCLEDHGAAAGFCSAVLEELSKAGVS-SeNVFCLAAPDEYIDKASRKTQLERCCVGSEEIsRQV 626
WP_010047482 548 LDKDTILRAVDALPLVVTVEEGTVEGGFGSAVLEAANAAGLDtR-NVVRRGIPDRFIEHGERNELLADIGLSADALaDLV 626
WP_099325262 543 LDKKLILSLVRKHKLILTVEDHALAGGFGSAVLEMVSDEKEDaG-KIVRMGIPDRFMEHGPREVILKNLGLDADGIaDTF 621
2O1X_A       618 LAELG 622
WP_013628927 624 RQLAK 628
WP_013564655 630 LEAAR 634
WP_015250556 622 LELAR 626
WP_075092753 625 RALHQ 629
WP_083713057 624 LELAR 628
WP_077026594 622 HELAG 626
WP_085756066 627 QARIR 631
WP_010047482 627 RTSRA 631
WP_099325262 622 IASLD 626
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