Conserved Protein Domain Family
lef-8

?
PHA03394: lef-8 
DNA-directed RNA polymerase subunit beta-like protein; Provisional
Statistics
?
PSSM-Id: 223073
Aligned: 53 rows
Threshold Bit Score: 1046.8
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
74229719    1 MTDVIVDFNNLYDKLKNKYNFEFYLNCNNKCENE-CTIKYLQERRSYFCCAV-DVQGRCVLHKCVLVIFGTWLDLKFR-- 76  
11068112    1 -MGIIEDFNKLYRYLES-FDLKFLLSCQSSVVI--TSLKQLQDRKTYFCCAV--RESKCILHNCVVVVIGTYLDKVFR-- 72  
14602368    1 -MCIITDFNNLYTHLAHTYNLDYQLSCHHHN----NTPLAMANIKTYFCCAVsVPLKKCVLHNCVVVIVGTWLDKRFR-- 73  
21686786    1 -MGVIEDFNHLYNTLTNKYQLEFVLTCQDLE----KKYTTLSQIKTYFCCAL--LDKKCVLHSCVVIILGTWLDKKFR-- 71  
32698649    1 MCNVVEDFDNLYNILHNKYNLTFSLYCQTKFAKE---HIKLNQIKSYFCCAIsECRTKCVLHNCVVVIIGTWLDKMFR-- 75  
33622319    1 -MCILSDFNNLYTNLASSYNLEYQLMCQQPQ----VTFANLDTIKTYFCCAVsVPLKKCVLHNCVIVVIGTWLDKKFR-- 73  
46309336    1 -MGVLDDFNSLYDLLRS-YNLEFHLSCQNLDKT--TSLRQLQDKKTYFCCGIsKELKKCVLHNCIVVVIGTLLDKEFR-- 74  
48843615    1 --MSIEDLNFMYKKLCG-DDETYILNCKNKKKISpNIFQLIDQKRSYVCCLYnNSVNQCILHQCVVIALQSWLDKLFRe- 76  
48843707    1 --MSVKDFNFLYQKLCN-RNEIYVLNCKHKRKNVpNIDQLINQKKSYVCCLYnEVLQQCILHQCVVVALQSWLDRKFRdi 77  
110645292   1 --MSLTDFNFLYQKLCN-KDEIYVLNCKQKKKIVpNIGELINQKKSYVCCLYnDLLQQCILHQCVVIALQSWLDKKFRdv 77  
74229719   77 -HNDTYkiTNMNGTFMIDGRNLSFPNILMNNNILLHNFYDKQYS--KNCKRMFLYGNVDKEKKINR---AIQLVYDKDDN 150 
11068112   73 -NNEPD--HGFTGTFIIDGRHFSFPNILMNNNILLHNFFDKQYArnKNLRRMFLYGNYDDDKIINR---AIQLVYDRGED 146 
14602368   74 -GDECN--YGFEGTFILDGRHFSFPNIMMNNNVLIHNFFDKQYArdKKMKRMFLYGNYDDDKTVNR---AIQLVYDKVDD 147 
21686786   72 -CDESD--FGFAGTFIHDGRHFSFPNIMMNNNVLVHNFFDKQYArdKRMKRIFLYGNYDDEKTVNR---AIQLVYDKVDD 145 
32698649   76 -NNEQD--YGFTGTFVIDSRHFSFPNIMMNNNVLVHNFFDKQYArnKKMKRIFLYGNYDDDRIVNR---AIQLVYDKIDD 149 
33622319   74 -GDECN--QVFAGTFVIDGRFFSFPNIMMNNNVLIHNFFDKQYArdKNMKRMFLYGNYDDDKTVNR---AIQLVYDKLDD 147 
46309336   75 -CHEDD--YGFAGTFIIDGRHFSFPNIMMNNNVLLHNFFDKQYArdKNMRRMFLYGNFDDEKSVNR---AIQLVYDRKED 148 
48843615   77 -DFDKHe-SMLGVCFIMNGHYYTIPNIMMNNNIQIHNFCSPQYS--RNAKRLYLYGNFCPEGDLKRygqSIQLVYEPSSD 152 
48843707   78 tTIDEDe-QVLGCCFVMNGHYYTIPNIMMNNNIQLHNFRSAQFS--SDAKRLYLYGNFCPDGDVKRygqSIQLVYESSTD 154 
110645292  78 gTVDEDe-QVLGCCFVMNRTLLHHSKYMMNNNIQLHNFRSPQFS--SDAKRLYLYGNFCPEGDVKRygqSIQLVYESSNN 154 
74229719  151 VLFARDVFARDYIVTMELNEALEMYLKRSGKWEPLNFIFDFNIDQSNHLVEDIKNIMKSDINYNIDSLANKIIYKHDYLL 230 
11068112  147 ILYVRDVYAKDYVVDSGINSVLRQYLRCSGKWKNMDFVFDFDDYND--IFDKLKRIMSIDINYQIDSLSNKIIYKHSYLL 224 
14602368  148 VLYVRDVYAKDYIVDSGINQILREYLKCSGKWPDMDFVFSFDDYTE--LFDTLKSIMSVDIPYQIDSLSNKIIYKHSYLI 225 
21686786  146 ILYVRDVYAKDYIVDSGINEILREYLKCSGKWSDMDFVFSFDDNTQ--LFDKLKCIMSVDIPYQIDSLSNKIIYKHAYLL 223 
32698649  150 VLYVRDVYAKDYIVDIGINKVLEQYLKSSGKWFEMDFAFEFSNSEE--IFDKIKTIMSVDINFEIDSLSNKIIYKYAYLL 227 
33622319  148 VLYVRDVYAKDYIVDSSINQILREYLMCSGKWPDMDFVFSFDDYKE--LFDVLKMIMGVDISYQIDSLSNKIIYKHSYLI 225 
46309336  149 VLYVRDVYAKDYIVDDGINEVLKEYLKCSGKWHEMDFVFDFEDYDE--IFNSLKQIMSVDIDYQIDSLSNKIIYKHSYLL 226 
48843615  153 VLHVRDVYGQDYLADDELIKKIVPYFCNNHKWPEVGFLFD-ENISTKVLKTTMKNIYT---GYHIDTLRNKLILSPSQLL 228 
48843707  155 ELHVRDVYGQDYFVDDKIIEKIVPYFQNNYKWPELGFLFD--NIDSDLIKSTMRHICT---DYHIDTLSNKLILSPSQLL 229 
110645292 155 ELHVRDVYGQDYFVDDKIIEKIFPYFQNNYKWPELGFLFDNIDSDLIKF-----TMRHICTDYHIDTLSNKLILSPSQLL 229 
74229719  231 SLMYAPILEEYTIMMKNDDKncdnvgdnyntiinnqrqqskeygqkktkinggadenhdnnengsnnkrkrtnnqafkpq 310 
11068112  225 KITYDNLLNIID-------------------------------------------------------------------- 236 
14602368  226 HLTYSTVLNKLRNLTVTDAD------------------------------------------------------------ 245 
21686786  224 ELTYNNVLNKLSV------------------------------------------------------------------- 236 
32698649  228 RLTYVTLLNKYKHYMHKFTS------------------------------------------------------------ 247 
33622319  226 YLTYSVILNKLKLLTSSLEN------------------------------------------------------------ 245 
46309336  227 LLTYSSLLNKIKNLTENGLG------------------------------------------------------------ 246 
48843615  229 ETFFCQ----------NKKLil---------------------------------------------------------- 240 
48843707  230 ETF---LLQTKKFILY---------------------------------------------------------------- 242 
110645292 230 ETF---LLQTKKFILY---------------------------------------------------------------- 242 
74229719  311 lkvidnkidvdinkiaGLKRKKLQTILFVKECKKVVETIVNGKLIYSVSKTFSKQK--KNFINYQDNSSNNNIEINPPPL 388 
11068112  237 ------------------EDNNKKTIAFPAESKKIHDSIIAGKLIQSVSKTLCKQK--KY--DQDFNSNNNNLEVFP--L 292 
14602368  246 -------------------NTKKKCVLFATESKKINDTIVMGKLIQSVSKTLSKQK--KY--DQEYNSNNNNLEIFP--L 300 
21686786  237 --------------------GGKKNIAFPVESKKIYDTIVMGKLIQSVSKTLSKQK--KY--DQDYNSNNNNLEVYP--L 290 
32698649  248 ----------------ENMGGKKKVILFASDSKKIYDTILSGKLIQSVSKTLSKQK--KH--DQDYNSNNNNLEVFP--L 305 
33622319  246 ------------------ETLKKKNILFMNESKKISDTIVMGKLIQSVSKTFSKQK--KY--DQEYNSNNNNLEIFP--L 301 
46309336  247 ----------------VRKKKLNMGILFPLESKKCSDTIISGRLIQSVSKTLSKQR--KN--DQEYNSNNNNLEIFP--L 304 
48843615  241 ---------------fMIERNIPVQKLVKESSRNMMQSIIDGQIFKSISKTLSTQKifRMNPRLQEYTSKTNRDVNIFDL 305 
48843707  243 ----------------LIDKQIPVTKLVNDSSRGVMQSIVDGQIFKGISKTLSTQKifKMNPRLQEHTSRTNRDVNVFDL 306 
110645292 243 ----------------LIDKQIPVAKLVKDSSRSMMQSIVDGQIFKGISKTLSTQKifKMNPRLQEHTSRTNRDVNVFDL 306 
74229719  389 KYRIGNEVVRITNDTMRQDMLMQQQDFVKFVDSFFHGEMTVAGKKFFLCRNVRLPAVDYHQVADKFKLLLANGLIYANDP 468 
11068112  293 DHRIGNEVLRIVNENLQQDMLKHTSDYVKFIDSFFHGEMTVAGKKFFVCHNVVLIDVDYTLVSDLFKKAIESNLFFKTCK 372 
14602368  301 RHRIGNEVLRVINENLQQDMLKHTADYIKFVDSFFHGEMTVAGKKFFLCHNVVLPDVDYKRVSLLFRELIHKNVLYTKKV 380 
21686786  291 KYRIGNEVLRIINENMQQEMLKHTSDYVKFVDSFFHGEMTVAGKKFFLCHNTLLPNVDYKLSAQLFTQLIDNGVFHTNC- 369 
32698649  306 RHRIGSEVLRIINENLQQDMLKHTKDYVKFVDSFFHGEMTVAGKKFFLCHNTRLPDLNYEMVGELFKKLETLNVFTIKPE 385 
33622319  302 RNRIGNEVLRVVNENLQQDMLKHTGDYVKFVDSFFHGEMTVAGKKFFLCHNVVLPDVDYKRISLLFRELIDKNIFYTKKN 381 
46309336  305 QHRIGNEVLRIINENLQQDMLKHTSDFVKFVDSFFHGEMTVAGKKFFLCHNVVLPDVNYKRASALFRQLIEEKFFFAKND 384 
48843615  306 KFKSSDEITKIISKDVSYKANMQYPDYRYFIDQCDHGELHAAGKTFTRSHDVILPNIDYDILKTMLTSMVNHQILSTNL- 384 
48843707  307 NFKNIDEILKIVSKDVSYKANMQYSDYRYFIDHCDHGELHAAGKTFTKTHDVILPNIDYSTIFRIFTTLINDQLISTSN- 385 
110645292 307 NFKNIDEILKIVSKDVSYKANMQYSDYRYFIDHCDHGELHAAGKTFTKTHDVILPNIDYSMILRIFTSLINDQLISTSM- 385 
74229719  469 snvDE---------------------------KNIRIAFNDRPTIYACRLDD-LQLIFYQLKRQYSPIELKLANRILFVN 520 
11068112  373 h------------------------------dNVYLISFNNRPTNLYCDKDD-VCKIYYLMKRNFSPVEIKLTKDILFIN 421 
14602368  381 ggeDEseltgekvkilnf-skkspnkvglvsnSELVVAFNNRPTKYYCNRDS-LYQIYYTMKRGYAPVEIKLTNNILFVN 458 
21686786  370 --------------------------------DDLMVAFNNRPTKFYCNRDN-LYTVYYTLKRRQSPIEIKVSNGILFVN 416 
32698649  386 t------------------------------sKSAIVAFNNRPTKYYCDTSThLYKIYYLLKRNYCPIEIKLISNILFIN 435 
33622319  382 ---VDesefirenlkf------kkssnkvgltKELVVAFNNRPTKYYCTKNL-LYQIYYILKRNRSPVEIKLTNSILFIN 451 
46309336  385 angGSqksfetyfelqgdinnkkvlnyakeapLVYLVSFNNRPTKYYCKRSD-LYCVYYILKRNYSPIEIKVSNGILFVN 463 
48843615  385 --------------------------------SKYLLVFNSCPTKYYIHDID-----NFIITVKSLPIEIRMFDNLICIN 427 
48843707  386 --------------------------------SKYRIVFNSCPTQYFVHNVEkFVKIIKAL-----PIEIRMFKSLICLN 428 
110645292 386 --------------------------------SKYRIIFNSCPTQYFVHNVE-----KFVKTIKLSTIEIRMFKSLMCLN 428 
74229719  521 HHEGMVCIKRMINIAG-KKITTLLTPFEYHNSYSILKKHPNIg-KIEE--NDD---VTSLMSKLVQYYYFGYTRIFSTIP 593 
11068112  422 HHEGMITLKKTVKICDkIMINTLQTPFEYHNSESIVRNFKMLn-FVDE--HDD---TTSLMSTMIRTYYNGYLQIFNTVP 495 
14602368  459 HHEGMVMLKRVVYIDNeIHIKTLQTAYEYHNEHSLLNSEDVLl-RCDE--TGPmntTASLMSTMVLEYYKNYLHIFNTIP 535 
21686786  417 HHEGMIMLKRVVCIDNnVRINTLQTPFEYHNENSLVNTDPAL--IFEE--NNT---TCQLMSTMILEYYRNHLHIFNTIP 489 
32698649  436 HHEGMLMLKKVVCIDSkIKINTLQTPYEYHNVESVVNKKETLldFDEI--VDN---TQSLMSTMILEYYKDHLHIFNTIP 510 
33622319  452 HHEGMIMLKRIVHINDeIYIKTLQTPYEYHNEQSILNTDPVF--RCDE--SGDmgtTLSLMSTMILEYYKNYLHIFNTIP 527 
46309336  464 HHEGMVMLKKLVRIHGtTIINTIQTPYEYHNKNSVVASSNNI----LEfyQENlstTSCLMSTMVLNYYKDYLHIFNTIP 539 
48843615  428 YHVGLIVKQVMLSINN-RIIPSYATPFEMHDELSMLKNNIIL--------QDDkkpIRSMLSRTTLYYCNDHTDVFHQIP 498 
48843707  429 YHVGLIMKKARLFVDD-GYIDTYVTPFELHHESSCFKDKIFL--------NESc--VRSLLSRTTLFYCNKHTDVFINIP 497 
110645292 429 YHVGLIMKKAKLFVDN-EYIDTYVTPFELHHESSCFKNKIFL--------NDSc--VKSLLSRTTLFYCNEHTDIFASIP 497 
74229719  594 VPKLIVSLTNLKNAMPVTCYNEELESsv-flKNLPVG----------NSVV-VSPRIQVNNKMFKLWTLVRDNKLMTAED 661 
11068112  496 VAKLIVSLTNLKNGMVVQCPTKIDNY-----DYLPLG----------NSVS-VDPKLMFNNRMFYLWTLVRDSNLKTAED 559 
14602368  536 VAKLIVSLTNLKNGMVVQKKGF---------KSLPVG----------NSVV-VEDSVYCNDRMFCLWTVVMDSRLKTAED 595 
21686786  490 VAKLIVSLTNLKNGMVVRHTGESG-------NLLPVG----------NSVL-VDESIYCNDRMFYLWTLVMDIKLKTAED 551 
32698649  511 VAKLIVSLTNLKNGMVVNTVENR--------DCCPLG----------NSVVlLDNKIYCNDRMFYLWTIVMDNCLKTAED 572 
33622319  528 VAKLIVSLTNLKNGMVVQKNDF---------NMIPIG----------NSVV-VDEKIYCNDRMFSLWTIVMDNKLKTAED 587 
46309336  540 VAKLIVSLTNLKNGMVVHTLDNQN-------VIQPLG----------NSVR-VDPSIYHNDRMFILWTLIRDSGLKTAED 601 
48843615  499 PAKIMVFMRNLKNASPVFHDNDFKPSqyikyMKNENR----------NCVVvNDPAHYCNDKMIFLWTMIGDIHLKTTED 568 
48843707  498 PAKIMVFMRNLKNASPVFIPS----------SFVPEKymkfmknenkNCIV-VDSKHYCNDKMIYLWTMIGDDRLKTSED 566 
110645292 498 PAKIMVFMRNLKNASPVFVQG----------SFVPTKytkfmknenkNCII-VDPKHYCNDKMIYLWTIIGDDRLKTTED 566 
74229719  662 PYIPDINLPIRLYNNKINKLKGKLN-HSKTETPVIKYFKSDE-NNFVQVEGGNFLYIAGVVVSNVKIGWIYDGKRYKIEA 739 
11068112  560 PYIPHSNLPIRIYHNKLHKLKGKLE--TDHNASSVIYKISYR-NNIIDVEGDNRLCLFGVLLSSNKINWNHDGKKYKIEY 636 
14602368  596 PYVPHARLPIKIYHNKINRIKGKVS----GDNNEFVYEKSGA-NNIIEVEGGNCLCMFGTLLCNNKINWNHDGKKYKIEF 670 
21686786  552 PYVPHTNLPIRIFHNKVNRLKGRIE----DVCTEIIYKQTEMpHNIIAVEGNNCLCLFGTLICSHKIAWNHDGKKYKIEY 627 
32698649  573 PYIPHVDLPIEIYHNKINRLRGKLFdDNTDSEFKIVYKKNESsFNAVYVDNGNYLCLFGTLICSNKINWNHDGKKYKIEY 652 
33622319  588 PYIPHTQLPIKIYHNKINRLKGKVN----AENCEFVYEKSNT-NNIIDVEGSNRLCIFGTMLCNNKINWNHDGKKYKIEY 662 
46309336  602 PYIPHNSLPIRIFHNKMNKVKGKLDcCGPYENVLIEYKASSH-NNIIDVEGWNRLCLFGTLVCGVKMNWNYDGKKYKIEY 680 
48843615  569 PYIPNSTQPFYLYNIRSIILRGSCI---ENKNGYFLLSNAND-FKIIETLFGYVLINVCQITSEFPINWNTLGKKLKITS 644 
48843707  567 PYVPNXNQPFVVYNLRSIILRGIST---LNENEYFRITSNVE-NNVLNTLYGYKLIGVCQITSQNAINWNTLGKKIKITS 642 
110645292 567 PYVPNFNQPFVVYNLRSIILRGTST---VNKNAYFRMTNNVE-SNVLETLYGYRLIGVCQITSQNAINWNTLGKKIKITS 642 
74229719  740 CKNKNFFLSKIYIYFREILNQRIECLESTMAVHND-TVYVKVTMITSTSDLQGIKICGIHGQKGVMNGSEDLTEWMAED- 817 
11068112  637 CMSKGHHVYKIYLYFRKLFGQLVERVHSECQIEDG-HVHLKICLVYSVSNLTGLKICGIHGQKGVLNESEDLTMYTADDd 715 
14602368  671 CTSKQWCVYKFYMYFRKVGGQVVERVDSEMTTDESgSVFVKLEMVYSVSDLEGLKICGVHGQKGVLHQAEDLSRFVAEDd 750 
21686786  628 CTSKQWHVYKFYMYFRRVHGQTVHKVHSEMVCDDNnNVFVKLELVYTVNDLEGLKICGVHGQKGVLNSAEDLSEYVTKD- 706 
32698649  653 CISKQWHVYKFYMYFRKVNGQQIHKIDSEMCHIDF-NVYINLELIYSVKDLEGLKICGVHGQKGVLSASEDLSVYISNDg 731 
33622319  663 CTSKNWHVYKFYMYFRKVEGQIIERVASEMNVDQSgGVFVRLELVYSVKDLEGLKICGIHGQKGVLHEAEDLSKFVAEDd 742 
46309336  681 CPSKSYHVYKFYMYFRKVKGQKVETVNSEMFYNDDgTVTVKLTLVYSVSDLEGLKICGVHGQKGILNSSEDLSRFKADSd 760 
48843615  645 LKSKNMYVYKIMMYVHDNFKKESLSVHCEAIKINK-EFIVKIRHVFCYDNFTGIKLCSIHGQKGVTNVESDLNDWVSED- 722 
48843707  643 LRSKNMYIYKIMMYFHNNFDIRSLKVKCEFEKINK-EYIVKIRHVFEYKDCVGIKICSVHGQKGVLNIASDLNCWISED- 720 
110645292 643 LKSKTMYIYKIMMYLHDNFDINTLDVKCEFQKINK-EYIIKIRHVFKYENYVGIKLCSVHGQKGVLNTPSNLNCWTSED- 720 
74229719  818 -GTSAQICLSPISFLSRQSNFDDIETKYVVRGGNHLDPDAKRYRIFNIPYMLFNNTPDNIFKEFIKSNYTGHEKVEGTRL 896 
11068112  716 eTVHAQICLSPISYISRQTNFDGIEHKYCTI-------KDKKYPLIKIPYMFFNNTPDNIYKEFIGKNITGYEKIEGTRL 788 
14602368  751 aSVHAQICLSPISYLSRQTNFNQLPVKYCRV-------NGERVPLVLIPYMFFNNTPDNIYKEFIGKNITGYEKLEGTRL 823 
21686786  707 -GVHAQICLSPISYLSRQTNFDGMVVKTCTK-------NGKRYPLILIPYMFFNNTPDNIYKEFIGKNITGYEKVEGTRL 778 
32698649  732 sGVHAQICLSPVSYLSRQTNFLNMPVKYYESE------DGKLYPIIRTPYMFFNNTPDNIYKEFIGKNVTGYEKLEGTRL 805 
33622319  743 pSIHAQICLSPISYLSRQTNFDNLPVKYSII-------NGNRIPLVLIPYMFFNNTPDNIYKEFIGKNITGYEKLEGTRL 815 
46309336  761 sSIHAQICLSPISYISRQTNMVGMRTEKCTI-------DGKCYPLVLIPYMFFNNTPDNIYKEFIGKNITGYEKLEGTRL 833 
48843615  723 -HIHPQLMISPISFLNRQTIIGDNIDKKFIRNGEQFSV------MYKIPYTIFHTTPDDAHTEYCDQIKTGLEKIEGTRL 795 
48843707  721 -GINPHLIISPISFLNRETILGDNIDKKIVYNGNNKAV------MYRIPYTLFYATPDDAHTEYCDKVKTGLEKIEGTRL 793 
110645292 721 -GINPQLMISPISFLNRETVLGVNIDKKIVYNGDSKAV------MYRIPYTLFYATPDDAHTEYCDKIKTGLEKVEGTRL 793 
74229719  897 DQWTINQSFVGNRLSESLQCVRGSSNLPD-NSGEYTVMGSLLHCNNTLIR 945 
11068112  789 DQWSINQSFIGNRLSESLHCVRNGNNTLN-ESGQYKIFKSLVHCNNIIID 837 
14602368  824 DQWSINQSFVGNRLAEGLHCVRNGNNSVE-NSGQYNVFQTLLHCNNIKVV 872 
21686786  779 DQWSINQSFMGNRLAEGLHCVRNGANTSQ-NSGQYNIFQTLLHCNNIKID 827 
32698649  806 DQWSINQSFMGNRMAESLHCVRGGNNNNI-NSGQYNVFRSLLHCNNIKIN 854 
33622319  816 DQWSINQSFVGNRLAEGLHCVRNGNNLIE-PSGQYKIFQTLLHCNNIKMI 864 
46309336  834 DQWSINQSFMGNRLAEGLHCVRNGTNTPH-PSGQYNIFKSLIHCNNISIS 882 
48843615  796 DNYTINNHYVSNMQTLNLQDIRSNSHDQHfNNHNYNTSVSLINTWHINLI 845 
48843707  794 DNYTINNHYVSNRQILNLQDIRANSHDQKfDNENYNTAVSLINTWHVRLD 843 
110645292 794 DNYTINNHYVSNRQILNLQDIRANSHDQNfDNENYNTAVSLINTWHVRLD 843 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap