Conserved Protein Domain Family
UPF0489

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pfam12640: UPF0489 
UPF0489 domain
This family is probably an enzyme which is related to the Arginase family.
Statistics
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PSSM-Id: 432689
Aligned: 15 rows
Threshold Bit Score: 104.544
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001627541    10 VKICENHDEVLFHIYRAIAGRYLPySGTTLIHFDSHPDMTIPP-------------------RLSASLVFNP-------- 62 
XP_002435099     7 VYVVEPHHHALHHIYRAIGRKKLPfSKVLMVHFDAHPDLVLPP-------------------GLDPARCRDR-------- 59 
XP_001688661   103 IFVVEDHHEVLTFLYRCLGSKHLPlQGNRIVHFDSHPDMCIPK-------------------HMPANYVFNK-------- 155
Q7SZF1          15 VWIVEDHHEVVQHIYRAIGSRHIPmKGIKMVHLDSHPDLLIPV-------------------NMPADTVYDK-------- 67  zebrafish
Q1RMV5          19 VWVVEDHQEVLPFIYRAIGSKHLPaSNISFVHFDSHPDLLIPV-------------------DMPADTVFDK-------- 71  cattle
WP_012160608    16 IYIVENHHEVIIPWSEYASHNE---TAPVLLTFDHHMDTRSAFyrysre--------vagleWRSVRDQLIAnvdin--- 81  Alkaliphilus ...
jgi:Maeo_1497   57 GRIVKKHHEAFYFWNELINNNKLK-TPFEVVHVDAHADLGMG--------------------DNSYDYIVGEllkipp-q 114
Q12VI5          19 LYFIIDHAAALIAWIKAFNEGIIS-RDATLFHLDKHTDF-----------------------HMNSDNIKKSktilgmdn 74  Methanococcoi...
jgi:Desal_3110  28 IFIMDNHRAAFWCWMESLKKG----ENLNIFHVDRHFDALFSAqdys-----------hfphAEFEDFGINEylecg--- 89 
EEC50737        11 VVVVESHQHALEHIHFMLRRKKIF-SDWSMLHFDAHPDLAVPHpivpaiacfqphrplaptrKTDKDDATSAtpknlyem 89 
XP_001627541    63 -----SELMEALSI-ADWI--LPAVYAGHIDRVVWIKPSWC------------------DQMTRERMTFCVGKHRESgfL 116
XP_002435099    60 -----DHVLDVVDI-ESWI--LPAALAGHLDRVLWVRSPWS------------------DQLPDGDQQFLIGSRDGQ--V 111
XP_001688661   156 -----DDLLDSISI-ENWL--MPTVFAGHVERIVWIKPPWS------------------EQIPKGKYAFHVGEFEGS--I 207
Q7SZF1          68 -----ETLLRELSI-ENWI--MPMVYAGHVSHVAWLHPYWA------------------QQIREGQHCMCVGKDSSTttI 121 zebrafish
Q1RMV5          72 -----ETLFGELSI-ENWI--MPAVYAGHFSHVVWLHPTWA------------------QQIREGRHHFLVGKDTSTttI 125 cattle
WP_012160608    82 ksstmISSLEKLCN-NEHI--DFALQTGMISDAVVFSLMNAdi-----------------------------------cT 123 Alkaliphilus ...
jgi:Maeo_1497  115 krnnpQYIDKYMNE-GNYM--AFAIANRWISKLTYITHPSG--------------------------------------- 152
Q12VI5          75 lelndFVTVELCDEnDEFI--VNAMWSGLIKDCISFHHEEG--------------------------------------- 113 Methanococcoi...
jgi:Desal_3110  90 ydndfFAVTPLFRW-DNYLglFIEKYGERISNWAFATHGKG--------------------------------------- 129
EEC50737        90 lddtaSGI-------AEWI--LPLALAAGLERIQWIRPAQSrlsqlpvgqnryrvgawiPHDTRSRKILSFLDLPESapV 160
XP_001627541   117 RVTSTEDYFLEELLYa--pMEELENVKQVELVILTAELKQILETIKIpakeqtdtykevlksataglsndlkpattcqhs 194
XP_002435099   112 WMTCPLPYFLSECIW----THQVDEGHELGLRVQTLDALLEAKPNDGg-------------------------------- 155
XP_001688661   208 RTDSTLEYFVSEGCYq--pEDKLENRKRLQLEVCSVEEYPVAEDTDL--------------------------------- 252
Q7SZF1         122 RVTSKDDYFLSDALYv--pLDHLEHPKELHLHVIRVDPVVSSQTTKLengqsgakipkaaqtqddmqskadtpctsssq- 198 zebrafish
Q1RMV5         126 RVTSTDHYFLSDGLYv--tEDLLENPKPLQLDVIMVKPYKLCHSQGEndavssakkpklaledsentasangdscseglg 203 cattle
WP_012160608   124 DYDNSKIYYIDPLCTskckKFPHDDECQLNVYDKVIEGEELLFKLNKinkfi---------------------------- 175 Alkaliphilus ...
jgi:Maeo_1497  153 ----------------------GNDILKEYLIDNEITNNIKLNND----------------------------------- 175
Q12VI5         114 ---SYDGILIEENQFa--pQKINFKCDGMDHNFYLFEGHDISLIDNIlnyq----------------------------- 159 Methanococcoi...
jgi:Desal_3110 130 --------------------SAPQSISYAAYEPWEFPAALGEL------------------------------------- 152
EEC50737       161 KVDWPCPYYMDDFSCv-----pTDELALPQLVNLEVSEAIDCNQQDL--------------------------------- 202
XP_001627541   195 salteqvkndsqnyftrlqetaegvtekvcvnelvlklsEVLSQEKLYILDIDMDFF 251
XP_002435099   156 --------------------------------------nAWQPEDRCFVLDIDLDFY 174
XP_001688661   253 --------------------------------------------AQGYILDIDLDYF 265
Q7SZF1         199 -------ppdgsaasgnisetakkkaddgstsyitdkllAVIEQTDPFILDIDLDFF 248 zebrafish
Q1RMV5         204 kd---tvtqtrdhtclqpscscsseshecqtavstgeilEILEKRDAFVLDIDLDFF 257 cattle
WP_012160608   176 -----------------------------------pgffISNRINKKFILDIDLDCF 197 Alkaliphilus oremlandii
jgi:Maeo_1497  176 ------------------------------------------EPVVEFEKIQGKDYI 190
Q12VI5         160 ------------------------------------eimNICECGRDFILDIDLDFF 180 Methanococcoides burtonii DSM 6242
jgi:Desal_3110 153 --------------------------------------------KGSWIFNLDLDYF 165
EEC50737       203 -------------------------------------------MCSSWELDICLDYF 216
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