P31791 8 VFLWVLTSLGAgigakIVKEGNPHQVYTLTWQIYSqsgevvwevqgnhalnTWWPALTPDFCQLAA-GLDTWDIPDRSPK 86 Feline endogenous v... P03386 21 IVLLILGGVNP-----VTLGNSPHQVFNLTWEVTNgdretvwaitgnhplwTWWPDLTPDLCMLALhGPSYWGLEYRAPF 95 AKR (endogenous) mu... P08360 21 GVLGILFVTGG-----LASRDNPHQVYNITWEVTNgeqdtvwavtgnhplwTWWPDLTPDLCMLALhGPTHWGLDNHPPY 95 Cas-Br-E murine leu... P07575 8 IWSLVILSQISq---vQAGFGDPREALAEIQQKHG------------------KP------CDCAGg-YVS-SPPINSLT 58 Mason-Pfizer monkey... P10269 8 IFLYNLVLv-------YAGFDDPRKAIELVQKRYG------------------RP------CDCSGg-QVS-EPPSDRVS 54 Baboon endogenous v... P21412 2 LCILILLLHPRlcpvtKGGLGKPSG--DIYTALFG------------------AP------CDCKGgTQTNNYATPTYTQ 55 Squirrel monkey ret... P03399 21 LILLVVWW----------GFGTTAEGHPL-QQLWE------------------LP------CDCSGg-YVSPDLPITPTP 64 Reticuloendothelios... P31796 21 LILLVAWW----------GFGTTAEGYPL-QQLWE------------------LP------CDCSGg-YVS-SIPTYYTY 63 Avian spleen necros... ABS11217 21 TLTLLALC---------------------------------------------RPI-QTWRCSLSLgNQQWMTAYNQEAK 54 P03383 5 FFLLLFSL-------------------------------------------THFPLAQQSRCTLTIgISSYHSSPCSPTQ 41 Human T-lymphotropi...
P31791 87 NLETSMEGTSQQLTPQG----------------CSKPWKR------CALTERDFYVCPRDNRDRa-TAHRCGGYEEYFC- 142 Feline endogenous v... P03386 96 SPPPGPPCCSGSSDSTPgcsrdceepltsytprCNTAWNRlklskvTHAHNGGFYVCPGPHRPR--WARSCGGPESFYC- 172 AKR (endogenous) mu... P08360 96 SSPPGPPCCSGDAGAVSgcardcdepltsysprCNTAWNRlklarvTHAPKEGFYICPGSHRPR--WARSCGGLDAYYC- 172 Cas-Br-E murine leu... P07575 59 TVS--CSTHTAYSVTNSlk------------wqCVSTP--------TTPSNTHIGSCPGECNTIsyDSVH----ASCYN- 111 Mason-Pfizer monkey... P10269 55 QVT--CSGKTAYLMPDQrw-------------kCKSIPK-------DTSPSGPLQECPCNSYQ---SSVH----SSCYT- 104 Baboon endogenous v... P21412 56 VTD--CGDKNAYLTYDTnwngvs-----spkwlCVRKPPS------IPVINGRPGPCPSECTNNikSQMH----SSCYS- 117 Squirrel monkey ret... P03399 65 SIA--VASPLPDLRVWLqgswgwgg-gfrqqweCVFKPKI------IPSVQEQPGPC--ECLTIa-TQMH----STCYE- 127 Reticuloendothelios... P31796 64 SLD--CGGSTAYLTYGSgtgswswgggfkqqweCVFKPKI------IPSVQGQPGPCPSECLQIa-TQMH----STCYE- 129 Avian spleen necros... ABS11217 55 FSISIDQILEAHNqs----------------pfCAKSPRYtl---dSVNGYPKIYWPPPQGRRRfgARA-----MVTYD- 109 P03383 42 PVCTWNLDLNSLTTDQRlh------------ppCPNLITYs-----GFHKTYSLYLFPHWIKKP--NRQGLGYYSPSYNd 102 Human T-lymphotropi...
P31791 143 -SAWGCETTG-----DAYWQPTSTWDLITITRNYTkpdscddrvereRKTSRHWRDPLSLPLKITFTDSGKRAlgwqTGY 216 Feline endogenous v... P03386 173 -ASWGCETTG-----RASWKPSSSWDYITVSNNLTs----------dQATPVCKGNEWCNSLTIRFTSFGKQAtswvTGH 236 AKR (endogenous) mu... P08360 173 -ASWGCETTG-----RAAWNPTSSWDYITVSNNLTs----------sQATKACKNNGWCNPLVIRFTGPGKRAtswtTGH 236 Cas-Br-E murine leu... P07575 112 -HYQQCNIGN-----KTYLTA-------TITGDRTpa---------iGDGNVPTVLGTSHNLITAGCPNGKKG----QVV 165 Mason-Pfizer monkey... P10269 105 -SYQQCRSGN-----KTYYTA-------TLLKTQT------------GGTSDVQVLGSTNKLIQSPC-NGIKG----QSI 154 Baboon endogenous v... P21412 118 -SFSQCTQGN-----NTYFTA-------ILQRTKSt-----------SETNPVTSGLQPHGVLQAGC-DGTVG----KSV 168 Squirrel monkey ret... P03399 128 -KAQECTLLG-----KTYFTA-------ILQKTKL-----------------GSYEDGPNKLLQASC-TGIW-----ETS 171 Reticuloendothelios... P31796 130 -KTQECTLLG-----KTYFTA-------ILQKTKL-----------------GSYEDGPNKLIQASC-TGTVG----KPV 174 Avian spleen necros... ABS11217 110 -CEPRCPYVGadrfdCPHWDNASQADQGSFYVNHQ-------------------------ILFLHLKQCHGIF-----TL 158 P03383 103 pCSLQCPYLG-----CQAWTSAYTGPVSSPSWKFH-------------SDVNFTQEVSQVSLRLHFSKCGSSM-----TL 159 Human T-lymphotropi...
P31791 217 TWGLR--WYLP-GKDRGIILKIKLKIDTItqt--vgpNLVLADQkTPVQLAIPVQPPRAPtqtprvnpvnstlspslgyp 291 Feline endogenous v... P03386 237 WWGLR--LYVS-GHDPGLIFGIRLKITDSgprvpigpNPVLSDR-RPPSRPRPTRSPPPSnstpt--------------- 297 AKR (endogenous) mu... P08360 237 FWGLR--LYIS-GHDPGLTFGIRLKVTDLgprvpigpNPVLSDQ-RPPSRPVPARPPPPSasp----------------- 295 Cas-Br-E murine leu... P07575 166 CWNSRpsVHISdGGGPQDKARDIIVNKKF--------EELHRSL-FPELSYHPLALPEARg------------------- 217 Mason-Pfizer monkey... P10269 155 CWSTTapIHVSdGGGPLDTTRIKSVQRKL--------EEIHKAL-YPELQYHPLAIPKVRd------------------- 206 Baboon endogenous v... P21412 169 CWNQQapIHVSdGGGPQDAVRELYVQKQI--------ELVIQSQ-FPKLSYHPLARSKPR-------------------- 219 Squirrel monkey ret... P03399 172 MLGPRcpCVCLdGGGPTDRFG-RICAEGL--------EEIIRHS-YPSVQYHPLALPRPR-------------------- 221 Reticuloendothelios... P31796 175 CWDPVapVYVSdGGGPTDMIREESVRERL--------EEIIRHS-YPSVQYHPLALPRSR-------------------- 225 Avian spleen necros... ABS11217 159 TWEIW-------GYDPLITFSLH----------------------KIPDPPQPDFPQLNS-------------------- 189 P03383 160 LVDAP-------GYDPLWFIT------------------------SEPTQPPPTSPPLVH-------------------- 188 Human T-lymphotropi...
P31791 292 apapgprppyPTSPS--RPGTGDRLLNLVQGVYLTLNLTAPNQTQDCWLCLTAK--PPYYQGVAIIGNFTNHTNAPLr-- 365 Feline endogenous v... P03386 298 -----etpltLPEPP--PAGVENRLLNLVKGAYQALNLTSPDKTQECWLCLVSG--PPYYEGVAVLGTYSNHTSAPAn-- 366 AKR (endogenous) mu... P08360 296 --------stPTIPP--QQGTGDRLLNLVQGAYLTLNMTDPTRTQECWLCLVSE--PPYYEGVAVLREYTSHETAPAn-- 361 Cas-Br-E murine leu... P07575 218 -----------------KEKIDAHTLDLLATVHSLLNASQPSLAEDCWLCLQSG--DPVPLALPYNDTLCSNFACLSnhs 278 Mason-Pfizer monkey... P10269 207 -----------------NLMVDAQTLNILNATYNLLLMSNTSLVDDCWLCLKLG--PPTPLAIP-NFLLSYVTRSSDnis 266 Baboon endogenous v... P21412 220 -----------------GPDIDAQMLDILSATHQALNISNPSLAQNCWLCLNQG--TSMPLAFPVNISSFNASQNN---- 276 Squirrel monkey ret... P03399 222 -----------------GVDLDPQTSDILEATHQVLNATNPQLAENCWLCMTLG--TQSPQ--PSRRMAMSLSMEIA--- 277 Reticuloendothelios... P31796 226 -----------------GVDLDPQTSDILEATHQVLNATNPKLAENCWLCMTLG--TPIPAAIPTNGNVTLDGN------ 280 Avian spleen necros... ABS11217 190 ----------------------DWVPSVRSWA-LLLNQTARAFP-DCAICWEPS--PPW----APEILVYNKTI------ 233 P03383 189 ----------DSDLEhvLTPSTSWTTKILKFIQLTLQSTNYS----CMVCVDRSslSSWHVLYTPNISIPQQTSSR---- 250 Human T-lymphotropi...
P31791 366 CSTTPRHGLTLTEVTGYGLCIG-------KIPPSHQNLCS------------QTVpSVGQGPYYLTAPNGTYWVCNTGLT 426 Feline endogenous v... P03386 367 CSVASQHKLTLSEVTGQGLCIG-------AVPKTHQVLCN------------TTQ-KTSDGSYYLAAPTGTTWACSTGLT 426 AKR (endogenous) mu... P08360 362 CSSGSQHKLTLSEVTGQGRCLG-------TVPKTHQALCN------------RTE-PTVSGSNYLVAPEGTLWACSTGLT 421 Cas-Br-E murine leu... P07575 279 CPLTPPFLVQPFNFTDSNCLYAhyqnnsfDIDVGLASFTNcs--------syYNVsTASKPSNSLCAPNSSVFVCGNNKA 350 Mason-Pfizer monkey... P10269 267 CLIIPPLLVQPMQFSNSSCLFSpsynsteEIDLGHVAFSNct--------siTNV------TGPICAVNGSVFLCGNNMA 332 Baboon endogenous v... P21412 277 CTPSLPFRVQPMPSQVYPCFFKgaqnnsfDIPVGVANFVNcs--------------sSSNHSEALCPGPGQAFVCGNNLA 342 Squirrel monkey ret... P03399 278 VLASLSGATHRVNRCQLLC--Read-nrtGIPVGYVHFTNctsiqesltrrvIYEiLRDYVLHRV------MYLCVEQHA 348 Reticuloendothelios... P31796 281 CSLSLPFGCNPPGSIDVSCYAGead-nrtGIPVGYVHFTNctsi-----qevTNEtSQMGNLTRLCPPPGHVFVCGNNMA 354 Avian spleen necros... ABS11217 234 SSSGPGLAL----------------------PDAQIFWVN-----------------------------TSSFNTTQGWH 262 P03383 251 TILFPSLAL----------------------PAPP-SQPF-------------------------------------PWT 270 Human T-lymphotropi...
P31791 427 PCISLQILNDTADYCILIELWPKIFYHDSE---YIYGHYEPGGRFRRD-PVSLTVALLLGGLtmgSLAAGIGTGTAAL-I 501 Feline endogenous v... P03386 427 PCISTTILDLTTDYCVLVELWPRVTYHSPS---YVYHQFERRAKYKRE-PVSLTLALLLGGLtmgGIAAGVGTGTTAL-V 501 AKR (endogenous) mu... P08360 422 PCLSTTVLNLTTDYCVLVELWPKVTYHSPD---YVYTQFEPGARFRRE-PVSLTLALLPEGLtmgGIAAGVGTGTTAL-V 496 Cas-Br-E murine leu... P07575 351 ---YTYLPTNWTGSCVLATLLPDIDIIPGSepvPIPAIDHFLGKAKR----AIQLIPLFVGL---GITTAVSTGAAGLgV 420 Mason-Pfizer monkey... P10269 333 ---YTYLPTNWTGLCVLATLLPDIDIIPGDepvPIPAIDHFIYRPKR----AIQFIPLLAGL---GITAAFTTGATGLgV 402 Baboon endogenous v... P21412 343 ---FTALPANWTGSCVLAALLPDIDIISGDdpvPIPTFDYIAGRQKR----AVTLIPLLVGL---GVSTAVATGTAGLgV 412 Squirrel monkey ret... P03399 349 ---YTALPNKWIGLCILASIVPDMSIIPGEepiPLPSIEYTAGRHKR----AVQFIPLLVGL---GITGATLAGGTGLgV 418 Reticuloendothelios... P31796 355 ---YTALPNKWIGLCILASIVPDISIISGEepiPLPSIEYTARRHKR----AVQFIPLLVGL---GISGATLAGGTGLgV 424 Avian spleen necros... ABS11217 263 HPSQRLLFNVSQG---NALLLPPISLVNLS-----TASSAPPTRVRRSpVAALTLGLAL------------SVGLTGInV 322 P03383 271 HCYQPRLQAITTDNCNNSIILPPFSLAPVP---------PPATRRRRAvPIAVWLVSAL------AAGTGIAGGVTGS-L 334 Human T-lymphotropi...
P31791 502 E-----TNQFKQLQIAMHSDIQALEESISALERSLISLSEVVLQNRRGLDLLFLQEG--GLCAALKEECCFYADHTGIVR 574 Feline endogenous v... P03386 502 A-----TQQFQQLQAAMHDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEG--GLCAALKEECCFYADHTGLVR 574 AKR (endogenous) mu... P08360 497 A-----TQQFQQLQAAMHNDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEG--GLCAALKEECCFYADHTGLVR 569 Cas-Br-E murine leu... P07575 421 S-----ITQYTKLSHQLISDVQAISSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 493 Mason-Pfizer monkey... P10269 403 S-----VTQYTKLSNQLISDVQILSSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYVNKSGIVR 475 Baboon endogenous v... P21412 413 A-----VQSYTKLSHQLINDVQALSSTINDLQDQLDSLAEVVLQNRRGLDLLTAEQG--GICLALQERCCFYANKSGIVR 485 Squirrel monkey ret... P03399 419 S-----VHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 491 Reticuloendothelios... P31796 425 S-----VHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 497 Avian spleen necros... ABS11217 323 AvsalsHQRLTSLIHVLEQDQQRLITAINQTHYNLLNVASVVAQNRRGLDWLYIRLGfqSLCPTINEPCCFL----RIQN 398 P03383 335 S-----LASSKSLLLEVDKDISHLTQAIVKNHQNILRVAQYAAQNRRGLDLLFWEQG--GLCKAIQEQCCFL----NISN 403 Human T-lymphotropi...
P31791 575 DSMAKLRERFKQRQKLFESQQGWFEGWYNKSPWFTTLVSSLMVPLILLLLILMFGPCILN----HLLQFIR 641 Feline endogenous virus ECE1 P03386 575 DSMAKLRERLSQRQKLFESQQGWFEGLFNKSPWFTTLISTIMGPLIILLLILLFGPCILN----RLVQFIK 641 AKR (endogenous) murine leuk... P08360 570 DSMAKLRERLNQRQKLFESGQGWFEGLFNRSPWFTTLISTIMGPLIVLLLILLFGPCILN----RLVQFVK 636 Cas-Br-E murine leukemia virus P07575 494 DKIKNLQDDLERRRRQLIDNPFW-TSFHGFLPYVMPLL----GPLLCLLLVLSFGPIIFN----KLMTFIK 555 Mason-Pfizer monkey virus P10269 476 DKIKTLQEELERRRKDLASNPLW-TGLQGLLPYLLPFL----GPLLTLLLLLTIGPCIFN----RLTAFIN 537 Baboon endogenous virus stra... P21412 486 DKIKNLQEDLEKRRKALADNLFL-TGLNGLLPYLLPFL----GPLFAIILFFSFAPWILR----RVTALIR 547 Squirrel monkey retrovirus P03399 492 DKIRKLQEDLLARKRALYDNPLW-NGLNGFLPYLLPSL----GPLFGLILFLTLGPCIRK----TLTRIIH 553 Reticuloendotheliosis virus P31796 498 DKIRKLQEDLIERKRALYDNPLW-SGLNGFLPYLLPLL----GPLFGLILFLTLGPCIMK----TLTRIIH 559 Avian spleen necrosis virus ABS11217 399 DSIIRLGDLQPLSQRVSTDWQWPWNWDLGLTAWVRETIHSVLSLFLLALFLLFLAPCLIKcltsRLLKLLR 469 P03383 404 THVSVLQERPPLEKRVITGWGL--NWDLGLSQWAREALQTGITILALLLLVILFGPCILR----QIQALPQ 468 Human T-lymphotropic virus 2
Jiyao W et al.(2023). "The conserved domain database in 2023.",