1I50,1IW7


Conserved Protein Domain Family
RNA_pol_B_RPB2
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cd00653: RNA_pol_B_RPB2 
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RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase complex contains two related members of this family, in each case they are the two largest subunits.The clamp is a mobile structure that grips DNA during elongation.
Links
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Statistics
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PSSM-Id: 238353
Aligned: 112 rows
Threshold Bit Score: 442.008
Created: 24-Sep-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 73 residues -Click on image for an interactive view with Cn3D
Feature 1:RPB1 interaction site [polypeptide binding site]
Evidence:
  • Structure:1I50_B; Saccharomyces cerevisiae RPB2 binds RPB1
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                        
1I50_B        43 LVSQQLDSFNQFVdy-----------------tLQDIICEDSTLileqlaqhttesdnisrkyEISFGKIYVTKPmvnes 105  baker's yeast
P37870        29 LIEIQTSSYQWFLde-----------------gLREMFQDISPIedft------------gnlSLEFIDYSLGEPk---- 75   Bacillus subtilis
AAF10490      45 LTEVQVNSFKAFLqddkapd-------qredvgLQSAFREVFPIdesekg--------rstgmVLDFIEYRLGEPe---- 105  Deinococcus ra...
AAF40591      29 LLATQIDSYAKFLqlenafd-------krtddgLQAAFNSIFPIvshn------------gyaRLEFVHYTLGEPl---- 85   Neisseria meni...
AAG59183      27 LLSIQLDSFQKFIeqdpe-----------gqygLEAAFRSVFPIqsys------------gnsELQYVSYRLGEPv---- 79   Escherichia co...
NP_102110     29 LIEVQKASYDQFLmvdepkg-------grpdegLQAVFKSVFPIsdfs------------gssMLEFVKYEFEGPk---- 85   Mesorhizobium ...
AAK44921      53 LLDVQTDSFEWLIgsprwresaaergdvnpvggLEEVLYELSPIedfs------------gsmSLSFSDPRFDDVk---- 116  Mycobacterium ...
Q93R88        27 LIEIQLDSYKWFLda-----------------gLYEVFDDINPIsnft------------gnlVLEFVGYTLDMDni--- 74   Clostridium pe...
ZP_00526634   27 RGVSDLEFVDYSIgnweckcg-----nlkglhhLRSTCRNCGATirtdp---------fhagdILCHHCGTFNKNvvtfc 92   Solibacter usi...
ZP_00769007   46 LIETQLKSFEWFKre-----------------gLRELFDEISPItdft-----------gknlELHFRDYTFGEPr---- 93   Chloroflexus a...

Feature 1                                                                                        
1I50_B       106 d------gvthaLYPQEARLRNLTYSSGLFVDVKKRtyeaidvpgrelkyeliaeeseddsesgkvFIGRLPIMLrsknc 179  baker's yeast
P37870        76 ------------YPVEESKERDVTYSAPLRVKVRLInketge------------------vkdqdvFMGDFPIMTd---- 121  Bacillus subtilis
AAF10490     106 ------------YSPEECREKDLTYEAPLYVKLELIhkdtgvikgf----------kpdsppeswvFLGNLPLMTf---- 159  Deinococcus ra...
AAF40591      86 ------------FDIPECQLRGITYAAPLRARIRLVildkeaskpt-----------vkevrenevYMGEIPLMTp---- 138  Neisseria meni...
AAG59183      80 ------------FDVQECQIRGVTYSAPLRVKLRLViyereapegt-----------vkdikeqevYMGEIPLMTd---- 132  Escherichia co...
NP_102110     86 ------------FDVDECRQRDLTYAAPLKVTLRLIvfdidedtgak---------sikdikeqdvYMGDMPLMTl---- 140  Mesorhizobium ...
AAK44921     117 ------------APVDECKDKDMTYAAPLFVTAEFInnntge------------------iksqtvFMGDFPMMTe---- 162  Mycobacterium ...
Q93R88        75 -----------kYSVEECKERDTTYAAPLKVAVRLQnketge------------------ikeqevFMGDFPLMTe---- 121  Clostridium pe...
ZP_00526634   93 nkcgdpvglqlkYDMQECQERGMTYAAPLKVTIRLTvyskdpetqkk---------svrdikeqevFFGEIPLMTd---- 159  Solibacter usi...
ZP_00769007   94 ------------YDEFECRERDLTYAAPLRVRVELRilttge------------------ikeseiFLGDFPIMTd---- 139  Chloroflexus a...

Feature 1                                                                                        
1I50_B       180 ylseatesdlyklkecpfdmgGYFIINGSEKVLIAQERSAGnivqvfkk-aapspisHVAEIRSalekg----------- 247  baker's yeast
P37870       122 --------------------tGTFIINGAERVIVSQLVRSP----------------SVYFSGKvdkngkkgf--tatvi 163  Bacillus subtilis
AAF10490     160 --------------------dGSFIINGADRVVISQIHRSP----------------GVYFTSSykgikkqyta-aiipm 202  Deinococcus ra...
AAF40591     139 --------------------sGSFVINGTERVIVSQLHRSPgvffehdkgkthssgkLLFSARIipy------------- 185  Neisseria meni...
AAG59183     133 --------------------nGTFVINGTERVIVSQLHRSPgvffdsdkgkthssgkVLYNARIipy------------- 179  Escherichia co...
NP_102110    141 --------------------nGTFIVNGTERVIVSQMHRSPg---------------VFFDHDKgkshssgkllfaarvi 185  Mesorhizobium ...
AAK44921     163 --------------------kGTFIINGTERVVVSQLVRSP----------------GVYFDETidkstdktlh-svkvi 205  Mycobacterium ...
Q93R88       122 --------------------qGTFIINGAERVIVSQLVRSPgvyynyn---vdktgkKLFSATVipn------------- 165  Clostridium pe...
ZP_00526634  160 --------------------nGTFIINGTERVIVSQLHRSP----------------GVFFERVpaqgyflg-----kii 198  Solibacter usi...
ZP_00769007  140 --------------------nGTFVYNGAERVVVSQLIRSP----------------GVYFKDEkeptsgrslh-takli 182  Chloroflexus a...

Feature 1                                                                                        
1I50_B       248 srfiSTLQVKLygreg-------------------------ssarTIKATLPYIKqdipiviifralgiipdgeilehic 302  baker's yeast
P37870       164 pnrgAWLEYETda------------------------------kdVVYVRIDRTRklpvtvllralgfgsdqeil----- 208  Bacillus subtilis
AAF10490     203 pkrgPWIELEFag-------------------------------dVLEMKVNKRKfpvslllrvlgmddasiralfteft 251  Deinococcus ra...
AAF40591     186 --rgSWLDFEFdp------------------------------kdLLYFRIDRRRkmpvtillkalgynneqildifydk 233  Neisseria meni...
AAG59183     180 --rgSWLDFEFdp------------------------------kdNLFVRIDRRRklpatiilralnytteqildlffek 227  Escherichia co...
NP_102110    186 pyrgSWLDIEFdskdvvharidrrrkipvtsllmalgmdgeeilsTFYNKITYVRagdhwripfnverfrglkavgdlvd 265  Mesorhizobium ...
AAK44921     206 psrgAWLEFDVdk------------------------------rdTVGVRIDRKRrqpvtvllkalgwtseqive----- 250  Mycobacterium ...
Q93R88       166 --rgAWLEYETds------------------------------ndVIYVRIDKTRklpisilgramgfgsdqell----- 208  Clostridium pe...
ZP_00526634  199 pyrgSWVEFEYdn------------------------------knILYVRIDRKRkfygsvflralglktdeqilrafyr 248  Solibacter usi...
ZP_00769007  183 pnrgAWLEFETnk------------------------------rdVISVKVDRKRkipvtillraitawiaeengngrwv 232  Chloroflexus a...

Feature 1                                                                                        
1I50_B           --------------------------------------------------------------------------------      baker's yeast
P37870           --------------------------------------------------------------------------------      Bacillus subtilis
AAF10490     252 peve---------------------------------------------------------------------------- 255  Deinococcus ra...
AAF40591     234 etfylssngvqtdlvadrlkgetakvdildkegnvlvakgkritaknirditnagltrldvepesllgkalaadlidset 313  Neisseria meni...
AAG59183     228 vifeirdnklqmelvperlrg----------------------------------------------------------- 248  Escherichia co...
NP_102110    266 adtgeivveagkkitarqarqlgekglkaikatdedllg----------------------------------------- 304  Mesorhizobium ...
AAK44921         --------------------------------------------------------------------------------      Mycobacterium ...
Q93R88           --------------------------------------------------------------------------------      Clostridium pe...
ZP_00526634  249 vskmeirdkkiywnvdegltglklshaittksgdtvvgqgkkitaslfkelqka------------------kiekveva 310  Solibacter usi...
ZP_00769007  233 pdneldkf------------------------------------------------------------------------ 240  Chloroflexus a...

Feature 1                                                                                        
1I50_B       303 ----------------------------------------------ydvndwqmlemlkpcvedgfviqdRETALDFIGR 336  baker's yeast
P37870       209 --------------------------------------------------dligeneylrntldkdntenSDKALLEIYE 238  Bacillus subtilis
AAF10490     256 -----------------------------------------pgedksagmgadeallrlftvlrpgdppkRDKAIQYLFG 294  Deinococcus ra...
AAF40591     314 gevlasandeiteellakfdingvkeittlyineldqgayisntlrtdetagrqaarvaiyrmmrpgeppTEEAVEQLFN 393  Neisseria meni...
AAG59183     249 ------------------------etasfdieangkvyvekgrritarhirqlekddvklievpveyiagKVVAKDYIDE 304  Escherichia co...
NP_102110    305 ------nylaedivnyatgeifleagdeidektlkvllgtgeqeikvldidhvnvgayirntlnvdknesRQDALFDIYR 378  Mesorhizobium ...
AAK44921     251 ---------------------------------------------------rfgfseimrstlekdntvgTDEALLDIYR 279  Mycobacterium ...
Q93R88       209 --------------------------------------------------eyfgeeerfkatiekdntktKEEALLEIYK 238  Clostridium pe...
ZP_00526634  311 pndlegahvvadvvdmttgevmidanseltttvmsklieagitefeiffperddvgtviaatirkdavktQNEALIEIYR 390  Solibacter usi...
ZP_00769007  241 -------------------------------------ghndqiielfrhvdtvpehpyihatldkdpsrnAKEALLELYK 283  Chloroflexus a...

Feature 1                                                                                        
1I50_B       337 RGtalgikkekriqyakdilq----------------------------------------------------------- 357  baker's yeast
P37870       239 RLrpgepptvenakslldsrffdpkrydlanvgrykinkklhiknrlfnqrlaetlvdpetgeilaekgqi--------- 309  Bacillus subtilis
AAF10490     295 LLadprrydlgepgrfkmntkl---------------------------------------------------------- 316  Deinococcus ra...
AAF40591     394 RLffsedsydlsrvgrmkfntrtyeqklse-------------------------------------------------- 423  Neisseria meni...
AAG59183     305 STgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalv-------------------- 364  Escherichia co...
NP_102110    379 VMrpgepptletaeamfnslffdseryd---------------------------------------------------- 406  Mesorhizobium ...
AAK44921     280 KLrpgepptkesaqtllenlffkekrydl--------------------------------------------------- 308  Mycobacterium ...
Q93R88       239 RLrpgepptvdsaislidslffdakrydlsrvgrykfnkklaiglrianqiaaedivdkltgevlvakgekisranaeei 318  Clostridium pe...
ZP_00526634  391 KLrpgdpptldtatqlfqgmffdprkydfs-------------------------------------------------- 420  Solibacter usi...
ZP_00769007  284 RLrpgdpptlenarsliesllfsprrydlakvg----------------------------------------------- 316  Chloroflexus a...

Feature 1                                                                                        
1I50_B       358 --------------------------------------------------------------keflphitqlegfesrka 375  baker's yeast
P37870       310 -----------ldrrtldkvlpylengigfrklypnggvvedevtlqsikifaptdqegeqvinvignayieeeiknitp 378  Bacillus subtilis
AAF10490     317 -------------------------------------------------------------gvqrqertllkfedgkfsd 335  Deinococcus ra...
AAF40591     424 ----------------------------------------------------aqqnswygrllnetfagaadkggyvlsv 451  Neisseria meni...
AAG59183     365 ----------------------eiyrmmrpgepptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilsk 422  Escherichia co...
NP_102110    407 ------------------------------------------------------lsavgrvkmnmrlelkaedtvrvlrk 432  Mesorhizobium ...
AAK44921     309 -----------------------------------------------------arvgrykvnkklglhvgepitsstlte 335  Mycobacterium ...
Q93R88       319 qnrginsvdvlvedrviriignhfvdihkcvdfdisdlnirelvhyptlreildnysdeetikeeikknmtrlipkhiik 398  Clostridium pe...
ZP_00526634  421 -----------------------------------------------------rvgrmkfniklydrsdataldkrtlds 447  Solibacter usi...
ZP_00769007  317 --------------------------------------------------ryklnknlwerdvrrdgakapdlsvrvllp 346  Chloroflexus a...

Feature 1                                                                                        
1I50_B       376 FFLGYMINRLLLCALDrk----------------dqDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYmqrtveea 439  baker's yeast
P37870       379 ADIISSISYFFNLLHGvg----------------dtDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERmsiqdtnt 442  Bacillus subtilis
AAF10490     336 AGLVDTIRYLMALQQGletvpmvdedgvvtdvpvaeDDIDHLGNRRVRTVGELLADQLRVGMGRMARGVRERmllgnpda 415  Deinococcus ra...
AAF40591     452 EDIVASIATLVELRNGhg----------------evDDIDHLGNRRVRSVGELTENQFRSGLARVERAVKERlnqaesen 515  Neisseria meni...
AAG59183     423 DDIIDVMKKLIDIRNGkg----------------evDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERlslgdldt 486  Escherichia co...
NP_102110    433 EDILAVVKTLVELRDGkg----------------eiDDIDNLGNRRVRSVGELMENQYRVGLLRMERAIKERmssieidt 496  Mesorhizobium ...
AAK44921     336 EDVVATIEYLVRLHEGqttmtvpg----gvevpvetDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERmttqdvea 411  Mycobacterium ...
Q93R88       399 DDIFATISYQIGLAYNig----------------yvDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERmtiqdqea 462  Clostridium pe...
ZP_00526634  448 DDFKSTIRYLLKLRKGig----------------avDDIDHLGNRRVRAVGELLENQFRIGLVRMERAIKEKmsvyqems 511  Solibacter usi...
ZP_00769007  347 RDIFRIVEQLILLNNGhg----------------rpDDIDHLGNRRVRTVGELIQQQFRVGLLRLERVVKERmslqdpas 410  Chloroflexus a...

Feature 1                                                                                  # ### 
1I50_B       440 hdfnmklaiNAKTITSGLKYALATgnwgeqkkamssragvSQVLNRYTYSSTLSHLRRTNt----pIGRDGKLAKPRQLH 515  baker's yeast
P37870       443 --itpqqliNIRPVIASIKEFFGSsq-------------lSQFMDQTNPLAELTHKRRLSalgpggLTRERAGMEVRDVH 507  Bacillus subtilis
AAF10490     416 --atptklvNNRPIVAAMREFFGRsq-------------lSQFKDQTNPLSDLRHKRRISalgpggLTRERAGFDVRDVH 480  Deinococcus ra...
AAF40591     516 --lmphdliNAKPVSAAIKEFFGSsq-------------lSQFMDQTNPLSEVTHKRRVSalgpggLTRERAGFEVRDVH 580  Neisseria meni...
AAG59183     487 --lmpqdmiNAKPISAAVKEFFGSsq-------------lSQFMDQNNPLSEITHKRRISalgpggLTRERAGFEVRDVH 551  Escherichia co...
NP_102110    497 --vmpqdliNAKPAAAAVREFFGSsq-------------lSQFMDQTNPLSEITHKRRLSalgpggLTRERAGFEVRDVH 561  Mesorhizobium ...
AAK44921     412 --itpqtliNIRPVVAAIKEFFGTsq-------------lSQFMDQNNPLSGLTHKRRLSalgpggLSRERAGLEVRDVH 476  Mycobacterium ...
Q93R88       463 --itpqqliNIRPVAAAIKEFFGSsq-------------lSQFMDQTNPLSELTHKRRLSalgpggLSRERAGFEVRDVH 527  Clostridium pe...
ZP_00526634  512 -tamphdlvNAKPVMAAIREFFGSsq-------------lSQFMDQTNPLSEITHKRRLSalgpggLSRERAGFEVRDVH 577  Solibacter usi...
ZP_00769007  411 --atpngliNIRPVVAAMREFFGGsq-------------lSQFMDQTNPLAELTNKRRLSalgpggLSRDRAGFEVRDVH 475  Chloroflexus a...

Feature 1        #  #    #                                                                       
1I50_B       516 NTHWGLVCPAETPEGqACGLVKNLSLMSCISvgtdpmpiitflsewgmepledyvphqspdatrvfvngvwhgvhrnpar 595  baker's yeast
P37870       508 YSHYGRMCPIETPEGpNIGLINSLSSYAKVNr------------------------------------------------ 539  Bacillus subtilis
AAF10490     481 RTHYGRICPIETPEGaNIGLISSLSSYAKVNd------------------------------------------------ 512  Deinococcus ra...
AAF40591     581 PTHYGRVCPIETPEGpNIGLINSLSVYARTNd------------------------------------------------ 612  Neisseria meni...
AAG59183     552 PTHYGRVCPIETPEGpNIGLINSLSVYAQTNe------------------------------------------------ 583  Escherichia co...
NP_102110    562 PTHYGRICPIETPEGpNIGLINSLATFARVNk------------------------------------------------ 593  Mesorhizobium ...
AAK44921     477 PSHYGRMCPIETPEGpNIGLIGSLSVYARVNp------------------------------------------------ 508  Mycobacterium ...
Q93R88       528 HSHYGRMCPIETPEGpNIGLINSLATYAKVNe------------------------------------------------ 559  Clostridium pe...
ZP_00526634  578 PTHYGRICPIETPEGpNIGLISSLSCFARINe------------------------------------------------ 609  Solibacter usi...
ZP_00769007  476 HSHYGRICPVETPEGpNIGLIGTMSTFARVNemgfletpyrkvy------------------------------------ 519  Chloroflexus a...

Feature 1                                                                                        
1I50_B       596 lmetlrtlrrkgdinpevsmirdirekelkiftdaGRVYRPLFIVEddeslghkelkvrkghiaklmateyqdieggfed 675  baker's yeast
P37870       540 ----------------------------------fGFIETPYRRVDpetgkvtgridyltadeednyvvaqan------- 578  Bacillus subtilis
AAF10490     513 ----------------------------------lGFIMAPYRKVEdgkvtnqveymtadiedrytiaqans-------- 550  Deinococcus ra...
AAF40591     613 ----------------------------------yGFLETPYRRVIdgkvteeidylsaieegryviaqana-------- 650  Neisseria meni...
AAG59183     584 ----------------------------------yGFLETPYRKVTdgvvtdeihylsaieegnyviaqans-------- 621  Escherichia co...
NP_102110    594 ----------------------------------yGFIESPYRKIVdgkltndvvylsameeakhhvaqana-------- 631  Mesorhizobium ...
AAK44921     509 ----------------------------------fGFIETPYRKVVdgvvsdeivyltadeedrhvvaqansp------- 547  Mycobacterium ...
Q93R88       560 ----------------------------------yGFIETPYRVVDkaegrvtgeiryftadeedqylvaqan------- 598  Clostridium pe...
ZP_00526634  610 ----------------------------------yGFIESPYRKVIkgavvdevkvlnpgdtdykvgdivrrgdmdeanr 655  Solibacter usi...
ZP_00769007  520 -----------------------nsvdnvqvwkekGILLRDVRDLRtgdliaakgtrvndeiarqitigllrgqilredi 576  Chloroflexus a...

Feature 1                                                                                        
1I50_B       676 veeytwssllneg--------------------------lveyidaeeeesiliamqpedlepaeaneendldvdpakri 729  baker's yeast
P37870       579 -----------------------------------------------------------arlddegafiddsivarfrge 599  Bacillus subtilis
AAF10490     551 ------------------------------------------------------------plnedntfadervlarrkgd 570  Deinococcus ra...
AAF40591     651 ------------------------------------------------------------dldsdgnligdlvtcrekge 670  Neisseria meni...
AAG59183     622 ------------------------------------------------------------nldeeghfvedlvtcrskge 641  Escherichia co...
NP_102110    632 ------------------------------------------------------------eldknggfvdefvicrsage 651  Mesorhizobium ...
AAK44921     548 ------------------------------------------------------------idadgrfveprvlvrrkage 567  Mycobacterium ...
Q93R88       599 -----------------------------------------------------------epldengcfidkkvtvrdkge 619  Clostridium pe...
ZP_00526634  656 klggkkqaaefea---------------------------hceylsaweedkwtiaqanveldekgrivpdlsnarqagn 708  Solibacter usi...
ZP_00769007  577 vdpdtdeliaeagteinralaerivelpikhikirpvvsqevdylsadeedrfvivqanapldqhnrfldtivscrfged 656  Chloroflexus a...

Feature 1                    #                 ### #                                             
1I50_B       730 rvshhaTTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMgvfltnynvrmdtmaniLYYPQKPLGTTRAM 809  baker's yeast
P37870       600 ntvvsrNRVDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVp----------------LMQPEAPFVGTGME 663  Bacillus subtilis
AAF10490     571 pllytpDEVDYMDVSPKQIVSINTSLIPFLEHDDANRALMGSNMQSQAVp----------------LVRADSPAVGTGVE 634  Deinococcus ra...
AAF40591     671 timatpDRVQYMDVATGQVVSVAASLIPFLEHDDANRALMGANMQRQAVp----------------CLRPEKPMVGTGIE 734  Neisseria meni...
AAG59183     642 sslfsrDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVp----------------TLRADKPLVGTGME 705  Escherichia co...
NP_102110    652 vmmaprENVDLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVp----------------LVRAEAPFVGTGME 715  Mesorhizobium ...
AAK44921     568 veyvpsSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVp----------------LVRSEAPLVGTGME 631  Mycobacterium ...
Q93R88       620 vlvvpsKDVDLMDVSPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVp----------------LLKPYAPIVGTGIE 683  Clostridium pe...
ZP_00526634  709 fvlkpkEEIEYIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVp----------------LLRADAPYVGTGME 772  Solibacter usi...
ZP_00769007  657 fvservERVDYMDVSPKQVVSVSTSLIPFLEHDDANRALMGSNMQRQAVp----------------LLRPDAPIVGTGME 720  Chloroflexus a...

Feature 1                                                                                        
1I50_B       810 EYlkf--------------------------------------------------------------------------- 814  baker's yeast
P37870       664 YVsgkdsgaavickhpgiverveaknvwvrryeevdgqkvkgnldk--ysllkfvrsnqgtcynqrpivsvgdevvkgei 741  Bacillus subtilis
AAF10490     635 RRvvtdsgtsvvsdvngrvsyvdaraiqvtlsedhrelnmnagnvr-tfelirftrsnqgtnldqhpivsvgdevkvgqv 713  Deinococcus ra...
AAF40591     735 RSvavdsataivarrggvveyvdanrvvirvhddeatagevgvdi---ynlvkftrsnqstninqrpavkagdvlqrgdl 811  Neisseria meni...
AAG59183     706 RAvavdsgvtavakrggvvqyvdasrivikvnedemypgeagidi---ynltkytrsnqntcinqmpcvslgepvergdv 782  Escherichia co...
NP_102110    716 PIvardsgaaigarrggivdqvdatriviratedldpgksgvdiy----rlmkfqrsnqntcinqrplvrmgdrvnkgdi 791  Mesorhizobium ...
AAK44921     632 LRaaidagdvvvaeesgvieevsadyitvmhdngtrrtyrmr----------kfarsnhgtcanqcpivdagdrveagqv 701  Mycobacterium ...
Q93R88       684 YKaavdsgvlpkaknagevvyvsanevrvkreldggvdtyrl---------lkfkrsnqgtcinqrpivakgdwvlkgev 754  Clostridium pe...
ZP_00526634  773 MVtardsgavvlnkragvvdsvdseriivrvegaahegqlsrevgadiyqltkfkrsnqntcinqkpivrvgqrvpkgav 852  Solibacter usi...
ZP_00769007  721 YRaardsgqvivarrdgvvvsttserivieeddgnqteyrlr----------kfmrsnqdtcinqrpavvrgqrvkagdv 790  Chloroflexus a...

Feature 1                             ####  # ###                                                
1I50_B       815 ---------reLPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQekkygmsitetfekpqrtntlrm 885  baker's yeast
P37870       742 ladgpsmelgeLALGRNVMVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEardtklgpeeitr-----dipnv 816  Bacillus subtilis
AAF10490     714 iadgpasergrLALGQNITIAIMPFDGFNFEDAICINEDLVRQDFYTSVHIEKDEIEardtklgpekitr-----dipgl 788  Deinococcus ra...
AAF40591     812 vadgastdfgeLALGQNMTIAFMPWNGYNYEDSILISEKVAADDRYTSIHIEELNVVardtklgaeditr-----dipnl 886  Neisseria meni...
AAG59183     783 ladgpstdlgeLALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVsrdtklgpeeita-----dipnv 857  Escherichia co...
NP_102110    792 iadgpstelgdLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMardtklgpeeitr-----dipnv 866  Mesorhizobium ...
AAK44921     702 iadgpctddgeMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDardtklgaeeitr-----dipni 776  Mycobacterium ...
Q93R88       755 ladgpstdlgeIALGKNIRMGFITWEGYNYEDAMLISEELVREDVFTSIHIEEYECEardtklgpeeitr-----dipnv 829  Clostridium pe...
ZP_00526634  853 ladgpctdlgeLALGRNVLVAFMPWRGYNFEDAILVSEKLVKEDYYTSIHIEEFEIEardtklgpeeitr-----dipni 927  Solibacter usi...
ZP_00769007  791 iadssstdqgeLALGQNVLVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEardtklgpeeitr-----dipnv 865  Chloroflexus a...

Feature 1                                                                                        
1I50_B       886 khgtydkLDDDGLIAPGVRVsgeDVIIGKTTPispdeeel-------gqrtayhsKRDASTPLRSTENGIVdqvlvtt-- 956  baker's yeast
P37870       817 gedalrnLDDRGIIRIGAEVkdgDLLVGKVTPkgvteltaeerllhaifgekareVRDTSLRVPHGGGGIIhdvkvfnre 896  Bacillus subtilis
AAF10490     789 seaalrdLDEDGIVRVGAEVkpgDILVGKTSFkgeseptpeerllrsifgekareVKDTSLRVQSGQGGIVvktvrfrrg 868  Deinococcus ra...
AAF40591     887 sermqnrLDESGIVYIGAEVeagDVLVGKVTPkgetqltpeekllraifgekasdVKDTSLRMPTGMSGTVidvqvftre 966  Neisseria meni...
AAG59183     858 geaalskLDESGIVYIGAEVtggDILVGKVTPkgetqltpeekllraifgekasdVKDSSLRVPNGVSGTVidvqvftrd 937  Escherichia co...
NP_102110    867 seealknLDEAGIVYIGAEVqpgDILVGKITPkgespmtpeekllraifgekasdVRDTSMRMPPGTFGTVvevrvfnrh 946  Mesorhizobium ...
AAK44921     777 sdevladLDERGIVRIGAEVrdgDILVGKVTPkgeteltpeerllraifgekareVRDTSLKVPHGESGKVigirvfsre 856  Mycobacterium ...
Q93R88       830 sedalkdIDERGIIRIGAEVrsgDILVGKVTPkgeteltaeerllraifgekareVRDTSLRVPHGEAGIIvdvkvftre 909  Clostridium pe...
ZP_00526634  928 adsflrnLDESGIIRIGATVkpgDILVGKVTPkgetqltpeekllraifgekagdVKDASLYCPPGIEGTIvdckifsrk 1007 Solibacter usi...
ZP_00769007  866 gqeslrnLDERGIIYIGAEVqpnDILVGKITPkgetdltaeerllraifgekareVKDSSLRVPNGVRGKVidvkvfsrs 945  Chloroflexus a...

Feature 1                                                                                        
1I50_B           --------------------------------------------------------------------------------      baker's yeast
P37870       897 dg------------------------------------------------------------------------------ 898  Bacillus subtilis
AAF10490     869 de------------------------------------------------------------------------------ 870  Deinococcus ra...
AAF40591     967 giqrdkraqsiidselkryrldlndqlrifdndafdriermivgqkanggpmklakgse--------itteylaglpsrh 1038 Neisseria meni...
AAG59183     938 gvekdkraleieemqxkqakkdlseelqileaglfsriravlvaggveaekl----------------------dklprd 995  Escherichia co...
NP_102110    947 gvekderamaiereeierlakdrddeqaildrnvyarlsdvlvgkeaiagpkgfkkgs---------tlskdtldeyprs 1017 Mesorhizobium ...
AAK44921     857 de------------------------------------------------------------------------------ 858  Mycobacterium ...
Q93R88       910 ng------------------------------------------------------------------------------ 911  Clostridium pe...
ZP_00526634 1008 gqekderskaieesqiqrlqrnlqdeiriltderakrlgtlldgkklladlhdektnkrllskdteltreliekmksrdl 1087 Solibacter usi...
ZP_00769007  946 eg------------------------------------------------------------------------------ 947  Chloroflexus a...

Feature 1                                                                                     # #
1I50_B       957 -----------------------------------------------nqdglkfVKVRVRTTKIPQIGDKFASRHGQKGT 989  baker's yeast
P37870       899 --------------------------------------------delppgvnqlVRVYIVQKRKISEGDKMAGRHGNKGV 934  Bacillus subtilis
AAF10490     871 -------------------------------------------gvdlkpgvremVRVYVAQKRQLQVGDKVANRHGNKGV 907  Deinococcus ra...
AAF40591    1039 dwfdirltdedlakqlelikvslqqkreeadelyeikkkkltqgdelqpgvqkmVKVFIAIKRRLQAGDKMAGRHGNKGV 1118 Neisseria meni...
AAG59183     996 rwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkiVKVYLAVKRRIQPGDKMAGRHGNKGV 1075 Escherichia co...
NP_102110   1018 qwwqfaveneklqselealrgqyddskkaleqrfmdkvekvqrgdemppgvmkmVKVFVAVKRKMQPGDKMAGRHGNKGV 1097 Mesorhizobium ...
AAK44921     859 --------------------------------------------delpagvnelVRVYVAQKRKISDGDKLAGRHGNKGV 894  Mycobacterium ...
Q93R88       912 --------------------------------------------ddlspgvnelVRCYIAQKRKISVGDKMAGRHGNKGV 947  Clostridium pe...
ZP_00526634 1088 krmrlankdprlneqideieemtsrqiavlekitdekiaklrkgdelppgviklVKVYIAMKRKLSVGDKMAGRHGNKGV 1167 Solibacter usi...
ZP_00769007  948 --------------------------------------------aelpvgvnqtVRVLLCQKRKISAGDKMAGRHGNKGV 983  Chloroflexus a...

Feature 1         #                     # #  #  #    #   #                                       
1I50_B       990 IGITYRREDMPFTAEGIvPDLIINPHAIPSRMTVAHLIECLLs------------------KVAALSGne---------- 1041 baker's yeast
P37870       935 ISKILPEEDMPYLPDGTpIDIMLNPLGVPSRMNIGQVLELHMg------------------MAARYLGih---------- 986  Bacillus subtilis
AAF10490     908 VSKIVRPEDMPYLEDGTpVDIVFNPLGVPSRMNLGQILETHLg------------------EVARLTGqk---------- 959  Deinococcus ra...
AAF40591    1119 VSRILPVEDMPYMADGRpVDIVLNPLGVPSRMNIGQILEVHLgwaakgigeridrmlkeqrKAGELREflnrlyngsgkk 1198 Neisseria meni...
AAG59183    1076 ISKINPIEDMPYDENGTpVDIVLNPLGVPSRMNIGQILETHLgmaak----------gigdKINAMLKqqqevaklrefi 1145 Escherichia co...
NP_102110   1098 VSRIVPVEDMPFLEDGThADIVLNPLGVPSRMNVGQILETHLg------------------WACAGMGkkigelidtyka 1159 Mesorhizobium ...
AAK44921     895 IGKILPVEDMPFLADGTpVDIILNTHGVPRRMNIGQILETHLgwca-----------hsgwKVDAAKGvpdwaarlpde- 962  Mycobacterium ...
Q93R88       948 ISRVLPEEDMPFLPDGRpLQICLNPLGVPSRMNIGQVLEVHLg------------------WAASALGwh---------- 999  Clostridium pe...
ZP_00526634 1168 IARILPEEDMPYLPDGTpVEIVLNPLGVPSRMNVGQILETHLg------------------WAAKALGv----------- 1218 Solibacter usi...
ZP_00769007  984 VSRVLPIEDMPFLPDGRpVDIILNPIGVPSRMNIGQILETHLg------------------WAAARLGfr---------- 1035 Chloroflexus a...

Feature 1                                                         #                              
1I50_B      1042 --------------------------------------------gDASPF-----------------------TDITVEG 1054 baker's yeast
P37870       987 --------------------------------------------iASPVF-----------------------DGAREED 999  Bacillus subtilis
AAF10490     960 --------------------------------------------fETPVF-----------------------DSVTEAT 972  Deinococcus ra...
AAF40591    1199 edldal---------------------tdeeiielasnlrkgasfASPVF-----------------------DGAKESE 1234 Neisseria meni...
AAG59183    1146 q-------------------------------raydlgadvrqkvDLSTFsdeevmrlaenlrkgmpiatpvfDGAKEAE 1194 Escherichia co...
NP_102110   1160 agdikplrktlesfmpandrnepireyddesivrlseqmrrgvsiATPVF-----------------------DGAHEAD 1216 Mesorhizobium ...
AAK44921     963 -----------------------------------lleaqpnaivSTPVF-----------------------DGAQEAE 984  Mycobacterium ...
Q93R88      1000 --------------------------------------------iATPVF-----------------------DGATETD 1012 Clostridium pe...
ZP_00526634 1219 --------------------------------------------qFATPVf----------------------DGATERE 1232 Solibacter usi...
ZP_00769007 1036 --------------------------------------------vATPVF-----------------------DGAHEDQ 1048 Chloroflexus a...

Feature 1                                                                       #       ### #    
1I50_B      1055 ISKLLREHgy--------------------------------------------qSRGFEVMYNGHTGKKLMAQIFFGPT 1090 baker's yeast
P37870      1000 VWETLEEAgm--------------------------------------------sRDAKTVLYDGRTGEPFDNRVSVGIM 1035 Bacillus subtilis
AAF10490     973 IKEMLEVAaaerlqarkddgfeldkreqevldragklgvidapgddyekgqmqlaRTGKSILYDGRTGEPISGPVVVGIM 1052 Deinococcus ra...
AAF40591    1235 IREMLNLAypsddpev--------------------------------eklgfndSKTQITLYDGRSGEAFDRKVTVGVM 1282 Neisseria meni...
AAG59183    1195 IKELLKLGdl--------------------------------------------pTSGQIRLYDGRTGEQFERPVTVGYM 1230 Escherichia co...
NP_102110   1217 INIMLEQAgl--------------------------------------------hTSGQSQLYDGRTGEPFDRKVTMGYI 1252 Mesorhizobium ...
AAK44921     985 LQGLLSCTlpnrdg------------------------------------dvlvdADGKAMLFDGRSGEPFPYPVTVGYM 1028 Mycobacterium ...
Q93R88      1013 IEDCLEKAgy--------------------------------------------nRNGKTVLRDGRTGEEFDNEVTVGIM 1048 Clostridium pe...
ZP_00526634 1233 IKKNLTAAgl--------------------------------------------pTSGKTALFDGMTGTQFEQPVTVGYI 1268 Solibacter usi...
ZP_00769007 1049 IKDLLVQAgl--------------------------------------------pADGKVTLYDGRTGERFDNPVTVGYA 1084 Chloroflexus a...

Feature 1                #  ### ##                    ###   # ## # ###### ######   #             
1I50_B      1091 YYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFrvhicgicglmt 1170 baker's yeast
P37870      1036 YMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGHGFGEMEVWALEAYGAAYTLQEILTVKSDDVvgrvktyeaiv- 1114 Bacillus subtilis
AAF10490    1053 YVMKLYHMVEDKLHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHVLQEMLTIKSDDIdgrdaayqsiv- 1131 Deinococcus ra...
AAF40591    1283 HYLKLHHLVDEKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVngrtkmyeniv- 1361 Neisseria meni...
AAG59183    1231 YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVngrtkmykniv- 1309 Escherichia co...
NP_102110   1253 YMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVagrtkvyeaiv- 1331 Mesorhizobium ...
AAK44921    1029 YIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTvgrvkvyeaiv- 1107 Mycobacterium ...
Q93R88      1049 YILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVvgrvktyeaiv- 1127 Clostridium pe...
ZP_00526634 1269 YMLKLSHLVDDKIHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYILQELLTAKSDDVygrakiyeaiv- 1347 Solibacter usi...
ZP_00769007 1085 YMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVvgrvktyeaiv- 1163 Chloroflexus a...

Feature 1                                  #   # # ## # #### # #
1I50_B      1171 viaklnhnqfeckgcdnkidiyqihiPYAAKLLFQELMAMNITPRLY 1217 baker's yeast
P37870      1115 ----------------kgdnvpepgvPESFKVLIKELQSLGMDVKIL 1145 Bacillus subtilis
AAF10490    1132 ----------------kgeevsgstiPESFKVLVKELHSLGLDVEVL 1162 Deinococcus radiodurans R1
AAF40591    1362 ----------------kgehkidagmPESFNVLVKEIRSLGLDIDLE 1392 Neisseria meningitidis MC58
AAG59183    1310 ----------------dgnhqmepgmPESFNVLLKEIRSLGINIELE 1340 Escherichia coli O157:H7 EDL933
NP_102110   1332 ----------------rgddtfeagiPESFNVLVKEMRSLGLNVELE 1362 Mesorhizobium loti MAFF303099
AAK44921    1108 ----------------kgenipepgiPESFKVLLKELQSLCLNVEVL 1138 Mycobacterium tuberculosis CDC1551
Q93R88      1128 ----------------kgenipepgvPESFKVLIKELQALCLDVKVL 1158 Clostridium perfringens
ZP_00526634 1348 ----------------kgeaaiepgvPESFNVLIRELQSLCLDVELM 1378 Solibacter usitatus Ellin6076
ZP_00769007 1164 ----------------kgepiqeagvPESFKVLIKELQSLGLSVEVL 1194 Chloroflexus aurantiacus J-10-fl

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