5H2D,4IC4


Conserved Protein Domain Family
Oxysterol_BP

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pfam01237: Oxysterol_BP 
Oxysterol-binding protein
Statistics
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PSSM-Id: 460126
Aligned: 318 rows
Threshold Bit Score: 172.728
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5H2D_A        44 SLWSVLKSMVGKDMTRMTLPVSFNEPTSLLQ-RVA-EDLEYAD-LLNQAA------------SfeD-STLRLLYVAIFTV 107 Kluyveromyces l...
XP_653552     45 EILKQLR--PGMSLERITMPTHVMEPRSLLE-KLT-DYFTHLD-LVNAAA------------Na-PtAEERMVKLVQFFL 106
OAV86921      20 FLKSIAT--FSGDLSSLTAPSFILSPTSLCE-FPS-YWGEPHR-EFAAIP------------Tg-KtPEERMVLTLRWFI 81 
XP_001487611  12 FLKSIAL--FNGDLLSLTAPPFILSPTSLCE-YSQ-YWAEHPE-LLVSPAslnisdeasnseKs-AmAEKRLIAVLKWFI 85 
Q0CNL9        19 FIKSIAS--FNGDLSSLTAPPFILSPTSLTE-YSA-YWAEHPG-LLVAPA------------Re-PdPEKRALAVLKWFL 80  Aspergillus ter...
EKG20344      23 FLKSIAS--FNGDLSSMTAPPFILSSTSLVE-FSS-YWAEHPQ-LFVAPA------------Sk-EdPAERALAVLKWFL 84 
Q4D8H2       340 IFQVLKTIRVGRSLSSVTLPVHILESRSLLE-MIS-DMFLAWDiLMPLALge------------vHhPVDRMRILLRWFF 405 Trypanosoma cruzi
EGC28403      62 FVKNHLK--VGADMTKLPIPATFTTPISFLTaIQT-QSAIFSH-LLTSAP------------Yi-KdDEQRFLQVLKYHL 124
EGG18569      43 IANAFRKLKVGSDVNSFVVPGSFILAQSTIT-RVAqNYCAHFD-LLIKAN------------Ni-QdEKERFLQVYRYFM 107
XP_004366315  73 SFISQLG--IGQELTKVSMPSMFLMPYSILElAGA-RYLKYFH-LLSAVS------------Se-PdQARRMAIVIQYFL 135
5H2D_A       108 SSYASTV--------KRVAKPFNPLLGETFEY-SRp--------dKSY-----------------------------RFF 141 Kluyveromyces l...
XP_653552    107 SGFYITPk--------ACKKPYNPLLGEFYRT-SWsha----dgsKTF------------------------------FI 143
OAV86921      82 STLK-GQftrretqtGTEKKPLNPILGELFLG-SWnsdssndknsTGEl----------------------------RLW 131
XP_001487611  86 STLR-SQycsrsesmGTEKKPLNPFLGEVFVG-KWtgaat-gdenAGEt----------------------------VLV 134
Q0CNL9        81 STLH-QQycsrseklGSEKKPLNPFLGELFLG-KWead-----adVGEt----------------------------TLI 125 Aspergillus ter...
EKG20344      85 STLK-QQyasrseklGSEKKPLNPFLGELFLG-KWed-------dAGTt----------------------------QLV 127
Q4D8H2       406 SAYNWRPk-------GAAKKPYNPILGEVFRC--KcpaplpvsspASLlsfpsprerfsqahdtspemnpkrsidcmHFL 476 Trypanosoma cruzi
EGC28403     125 TWPKMYFp----------KNPLNPILGEIYECsVNhidektsqviEGDt---------------------------tNFF 167
EGG18569     108 STPRIS---------GEKKKPLNPVLGETCQAyADipnqekgstsSRV-----------------------------HVF 149
XP_004366315 136 ACIRDG---------NFQRKPYNALLGETHNCfIRypsaeedgktSTA-----------------------------RFI 177
5H2D_A       142 TEQVSHHP-PISATWT--ES--PKWDF-FGESFVDSK--FNGRSFD----FKH-LGLWYLTIrp----dSn-gKEELYTY 203 Kluyveromyces l...
XP_653552    144 AEQTSHHP-PVSSIYA--CNrqAGWVG-TGSLDFVTT--FNGLSAS----AGI-QGLIKAKFt------K---FDEDYEW 203
OAV86921     132 TEQVSHHP-PVSAYCL--INakAGVSY-QGHCGQKTS--FSGKSVI----VKQ-VGHGLLRVkl---pdN---TIESYLI 194
XP_001487611 135 SEQVSHHP-PVTAYAV--LNdkNGVKL-QGYNGIKSW--ISATSIN----VQQ-FGHAILEVg------P-----ESFLI 192
Q0CNL9       126 SEQVSHHP-PATAYAI--RNekHGVEL-QGYNAQKAS--FNGT-IL----IKQ-IGHALLTFtppgadrNdpaQKEQYLI 193 Aspergillus ter...
EKG20344     128 SEQVSHHP-PVTAYSI--WNdkHGVRL-TGYCGQKAS--FSRT-IN----VKQ-IGHAVLHId------A---YDEDYLI 186
Q4D8H2       477 AEQVCHRP-PVSAFYA--EL--PDLIVaEGVFVPHSK--LVSLNCV----ASLsSSSVLVRFp------K---TGWSFRF 536 Trypanosoma cruzi
EGC28403     168 AEQVSHHP-PISCFHFwnDK--HGFKY-DAKEQITPV--FKGKCIRvnmdVKT-----CITLenk--htK---AKETYVN 231
EGG18569     150 SEQILHHPlPISCTHV--YSkeEGISV---SYYHPVRgnFMGTYVK----LSF-EGEMVIKLdr----fG-----EVYKS 210
XP_004366315 178 AEQVTHHP-PLTAFHI--ETs-EGLTM-DCNVQFSAK--FHMNSVS----IVT-SGDIIIKVpmresdgEp-aHEEVYVI 244
5H2D_A       204 KKPN--NQVVGILLGNPQVDNYGDVKIV--NH-Nt--GDYCMIHFKARG-Wr-SSSAYEVKGEVY--N------AKG-GK 265 Kluyveromyces l...
XP_653552    204 NFPM--ALVTGIYIPPLTMEIGGVLNFV-----CkqsGyKAKVEFKTMSmFssS-NYRQINGIIS--Dp-----E-G-KP 266
OAV86921     195 TLPK--LRIEGLWMASPYIELTENSHIQss------sGyHTVMEFKGKGyFt--gKAHSFTAKIY--Sqpk-itSGV-SP 260
XP_001487611 193 TLPP--LHIEGLITASPFVELEGTSYIQss------sGyIAKLDFSGRGyFs--gKKNTFKARVF--PdllssqNKE-SA 259
Q0CNL9       194 TLPS--LHVESLIYGTPFMELDKSTRIVss------tGyIAKIDYSGKGwLs--gKKNTFTASLF--Kes---eGEK-KP 257 Aspergillus ter...
EKG20344     187 TLPS--LHIEGLITGSPYIELNRQSYITss------sGyTARIDYSGRGwIs--gKKNSFTAALY--Phd---kTEK-DA 250
Q4D8H2       537 SLPH--AYASGVVAGTPRLELGGVVRLEdcQSlA-----HVTVDFRRKGfF--SGKHDEVVAKISteD-------GK-EI 599 Trypanosoma cruzi
EGC28403     232 DKFP--EGYLRLLRWK--FEFSGKYTFS-----CpetGYTATINFKDKPiI---------GGKWH--DiqvivsKNN-EN 290
EGG18569     211 TMPT--IAIRFLR---DFVEYLGKVELT-----CnknDYRIKTTFCPKSlLf--gSNNVVEAKVY----------KGkEK 268
XP_004366315 245 DKGLpdAIVKNVIFGTRSINWTDSVEIM-----CqttNTSATLHFDKNEfV---------KGDIYeyNe----eKNEeEH 306
5H2D_A       266 EWIFGGRWNE-SVSA----KkVLKPNSleemqvdelkh-------------------------svthtssggpkYDGTRF 315 Kluyveromyces l...
XP_653552    267 IYEINGRYDE-ELFI----TdKRTKEKksffkveelkkt-----------------------keqrlvrefdklHPFESE 318
OAV86921     261 VHEIEGQWHGlSKFV----KqVPKWWQgsgdkfldltdek----------------------leeitvqdiskqGPLESR 314
XP_001487611 260 ICTIAGQWLGkSYIT----KgGSTPKKtdilfydahspa------------------------thlkvkpieeqHQLESR 311
Q0CNL9       258 LYTAQGQWSD-SFVI----TnPRTKETvdkysvkeskt-------------------------tplqvapleeqDLYESR 307 Aspergillus ter...
EKG20344     251 IYTIDGQWTE-SFTI----K-KKKETIetydartnktt--------------------------pltlapvddqDELESR 298
Q4D8H2       600 AEEYVGLWNG-PIYSrgtgKgVDVGKKrqnhhlrpqegdgkellfdaeifqqqrgmpccrpyayplhagnddhpYPKQSR 678 Trypanosoma cruzi
EGC28403     291 LYDIHGTHVD-VLTI------TNLKNKtsevfmnytilr-----------------------teptieepfeqlKDNTSQ 340
EGG18569     269 IQKIKGCWDQ-ELKI------NSEYKKddyttlckrtdl------------------------titeiqfpsslLDTDST 317
XP_004366315 307 HATLSGYLNS-TVNI------EYFDTPassekskkksk--------------------------kkskskkqfgPTDTVL 353
5H2D_A       316 N-----------------------VWHVnerpefpfnltkfaVTLnapqphllpwlpptdtrlrpdqrAMEEGRYDEAAT 372 Kluyveromyces l...
XP_653552    319 K-----------------------LFKR--------------VSD-----------------------AIIKNDQNLAME 338
OAV86921     315 R-----------------------VWKN--------------VAD-----------------------GIRSGDFEAASS 334
XP_001487611 312 K-----------------------AWAK--------------VAD-----------------------AIAKSDYDLIHK 331
Q0CNL9       308 R-----------------------AWKD--------------VAE-----------------------GILRSDMNAVSA 327 Aspergillus ter...
EKG20344     299 R-----------------------AWQK--------------VAV-----------------------AIQAGDMDTTGR 318
Q4D8H2       679 A-----------------------VWKD--------------LTA-----------------------AIRQGDVEAASN 698 Trypanosoma cruzi
EGC28403     341 K-----------------------VWKG--------------VAD-----------------------GFAKKDSRKAGV 360
EGG18569     318 K-----------------------VWGD--------------LFE-----------------------AAKSGTSKDITR 337
XP_004366315 354 FeseklqpnhtlypkqtdpinslnVWKE--------------VTK-----------------------HIVANDMASSDV 396
5H2D_A       373 EKHRVEERQRSVRKKR--EEKnitYQQRWF---KKEI------------------------------H---P----VTKc 410 Kluyveromyces l...
XP_653552    339 EKFVLEEAQRTQRKLNdeKKVe--QERRLF---DKQGs----------------------------dH---------Dw- 375
OAV86921     335 AKSKLENEQRAKRKEElaNGTp--WQMSHF---DRVDsdeeyar-----------------laemcsHs-pP----TEEa 387
XP_001487611 332 EKSLIENSQREMRKKEeeSGIp--WKARWF---DEVDyeqgpdhdaflnlcnlallsiknapsgtakKakhD----TGSa 402
Q0CNL9       328 AKGKIENAQRQMRKTErdENRt--WERRFF---KRVDesqld---------------------eqfkQlfqkadlesles 381 Aspergillus ter...
EKG20344     319 EKSIIENRQREMRRVEkeEGRe--WERRYF---TRTDefpvfek-----------------laariqEpieA----DKTn 372
Q4D8H2       699 AKKIVEEAQRAERRQLeaEGRv--YTPKFF------Ef-----------------------------Ig--AgklsDVNe 739 Trypanosoma cruzi
EGC28403     361 EKQRIEEAQRKKAKANlaKDpnfvHKPAFFipnPES-------------------------------------------- 396
EGG18569     338 EKTKVEEAQRKIAAERkaNGVe--WVPKHF---HKQ-----------------------------------GdeciKKKk 377
XP_004366315 397 VKKEIEDEQRKRLRATkeEEK---KERVYFk--------------------------------------------fDEEq 429
5H2D_A       411 dywK--FNGEYWKQRR 424 Kluyveromyces lactis NRRL Y-1140
XP_653552    376 ---K--YKWENWNKYD 386
OAV86921     388 yyfK--YEKEYNQEIL 401
XP_001487611 403 khwR--FNREKWDGES 416
Q0CNL9       382 ertggvwrfdpasvnd 397 Aspergillus terreus NIH2624
EKG20344     373 gvwK--Fdsekaakyl 386
Q4D8H2       740 etlS---RQENWRFTA 752 Trypanosoma cruzi
EGC28403     397 ---SdgVKPEYIYKRS 409
EGG18569     378 skyQ---KKKRYKREN 390
XP_004366315 430 erwV--Fk--GFPTPN 441
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