1KQ7


Conserved Protein Domain Family
FumC

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COG0114: FumC 
Fumarate hydratase class II [Energy production and conversion]
Fumarate hydratase class II is part of the Pathway/BioSystem: TCA cycle
Statistics
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PSSM-Id: 439884
Aligned: 463 rows
Threshold Bit Score: 609.719
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KQ7_A         1 MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGL--------LSEEKASA 72 
WP_012909738   1 MSEYRVERDSMGEVQVPAQAYYSAQTQRAVENFPISGWPLPAALVHAMGLVKLACATANRDLGKltrtgknkLDDQQVAA 80 
WP_013109128   1 MTETRIETDSMGEVHVPAKAYYSAQTQRAIENFPVSGWTLHPELIRAMGWVKYACGVANRDLGKlthsgknkLTDQQVQF 80 
WP_013627712   1 MSDFRTEHDSMGEVQVPRLAYYGAQTQRAVHNFPISGWTLHSNLIHAMGLVKFACARANYDLGKltgsgknpLSEDQVKA 80 
NP_867926      1 MTDFRTERDSMGEVRVPQNAYYGAQTQRAVENFPVSGWQLPPSMIAAMGRVKLACGIANRDLGKltgsgknpLSDGQVES 80 
WP_009511645   1 ---MRTEKDSMGPMQVPDDALYGASTQRAVLNFPVSGRPLPDGFIRGIGLVKLACARANEELGR--------LSPEKSKL 69 
WP_014436910  12 EGSTRTERDSMGEMQVPAQALYGASTARAVANFPIAHRPLAPAILHAFGELKAACAEVNLEAGL--------LEEDLARA 83 
WP_075091346   1 MSEFRIEKDSMGDVQVPAQAYYGAQTQRAVENFPVSGWPLHKDLIHAMGIVKYACGVANRDLMKlqdtgkvrLNAKQIDA 80 
WP_077026235   1 MSEFRTERDSMGPVQVPAEAFYGAQTQRAVENFPISGWELPPELIHAMGRVKYACGVANRDLGKltgtgknpLNDEQVSA 80 
WP_096055039   1 ---MRTERDSMGEMPVPDEALYGASTQRAVLNFPISGRPMPPAFIRGLGLVKLACAAANQELGL--------LTPEKSAL 69 
1KQ7_A        73 IRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVR--GM------ERKVHPNDDVNKSQSSNDVF 144
WP_012909738  81 LLEACREVADGKLDKEFPVDVFQTGSGTSSNMNTNEVIANRAIEILGGNRf-EK------EKPIHPNDHVNMGQSTNDIF 153
WP_013109128  81 MLDAALEVAHGKWDGEFPIDVFQTGSGTSSNMNVNEVISNRAIELAGGDRf-EA------KKPIHPNDHVNMGQSTNCTF 153
WP_013627712  81 LQDAAREVAAGQHDDQFPIDVFQTGSGTSSNMNCNEVISNRAIELMGGDRf-DD------KKPIHPNDHVNMGQSTNDTF 153
NP_867926     81 MLSAAKEVAEGQLADQFPVDVFQTGSGTSSNMNINEVLSNRAIEIDGGDRm-AE------EKSIHPNDHINMGQSTNDTF 153
WP_009511645  70 IQEAAREIAEGKLSVHFPVDVFQTGSGTSTNMNANEVISNRASQLAGQPV--GS------KKPIHPNDDVNLGQSSNDII 141
WP_014436910  84 IVAAAEEVARGEHDGHFPVDVYQTGSGTSTNMNANEVIANLANQKLGLPSspGGdrdpnaKPRVHPNDHVNLGQSSNDTF 163
WP_075091346  81 MLAAAKEVAAGKFDGEFPIDVFQTGSGTSSNMNANEVIANRAIEILGGDRf-SK------DKPVHPNDHVNMGQSTNDTF 153
WP_077026235  81 MLQACEDVVDGSLDDQFPIDVFQTGSGTSSNMNVNEVISNRAIEILGGDRf-AA------DKPVHPNDHVNMGQSTNDTF 153
WP_096055039  70 IQQVAHELLQGKLLEHFPVDVFQTGSGTSTNMNANEVIANRASQLSGQTI--GS------KKPLHPNDDVNLGQSSNDVI 141
1KQ7_A       145 PTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAE 224
WP_012909738 154 PTAIHVAVAMQIKSDLIPALERFQNVLATKAAEWDKIIKIGRTHLADATPLRLGQEIGGLARQMEMSIQRAKRAIDSVLE 233
WP_013109128 154 PTAIHVAVAHSIKTQLIPALKNLANTLAEKAKAWDKVLKIGRTHLADATPIRLGQEFSGFARQLELSVQRAQQAMAAVME 233
WP_013627712 154 PTAIHVATAIAIQNELIPALERLQKALAAKAEQWDKIIKIGRTHLADATPIRLGQEFSGFARQLELSVERAKTAMKAVLE 233
NP_867926    154 PTAIHVAAAYEIENRLLPALRRMHESLTEKAQAWDKIIKIGRTHLMDATPLRLGQEFGGFARQIELSIARAEAARDAVLE 233
WP_009511645 142 PTVLHVSVAHALQTHLRPALAHLRDALDAKAKAFAHIVKIGRTHLMDATPLTLGQEFSGYAAQASKSVERVDKAIVALLE 221
WP_014436910 164 PTAMHIAVSRQIHDRLVPALKKMTDRLAEQAMRWDGITKIGRTHVMDATPIRVGQVFSGYAEQGECAARFAMLALKSTND 243
WP_075091346 154 PTAIHVAVAVSIRKTLIPALKRFEDVLSRKAKEWDKIIKIGRTHLADATPLRLGQEFGGFARQLTLSIERAERALTSVLE 233
WP_077026235 154 PTAIHVAVGTSIVNDLLPALQRFADELQKKADDWDQIIKIGRTHLADATPLRLGQEFGGFARQLQLSIDRAKRAVDAIAE 233
WP_096055039 142 PTALHVSVALALHEQLHPALKHLHAALAAKSEAFSEIVKIGRTHLMDATPVTLGQEFSGYAAQASKAAVRVEKAIVALRE 221
1KQ7_A       225 -LALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPR 303
WP_012909738 234 -LPAGGTAVGTGINTHPEFGRRVAEALSRETSIPFVEAVNHFEGNAQRDGLVECSGQLRTIASTLFNVSNNIRWLGSGPR 312
WP_013109128 234 -LPVGGTAVGTGINTHPEFSSRVCAVLAKELGIPFIEAVNHFEANAQRDGLVECHGHLRAIAVTLFNVANNIRWLGSGPR 312
WP_013627712 234 -LPVGGTAVGTGINTHPDFGATVASVLAEETNIPFSEALNHMEANAQRDGLVECHSELKTIANTLFNMSNNVRWLGSGPR 312
NP_867926    234 -LPVGGTAVGSGINTHPEFGARVAASLSEQTGIAFIEAVNHFEGNANRDGLVDSHGGLKCVAQTLLGLANNIRWLGSGPR 312
WP_009511645 222 -LAIGGTAVGTGINCHPAFPAAVIRVLNEETGLAFIEARNHFEAQGGRDDAVEVAGLLATIAASLTKIANDIRLLGSGPR 300
WP_014436910 244 gVPIGGTAVGTGINTLPGFGGKVCQKLSERTGLRFQEANNHFCAQSCKDEFVYAHGCLKTGAIALSKIASDIRLLGSGPR 323
WP_075091346 234 -LPVGGTAVGSGINTHPEFGHRVAESVAGETGIPFVEAVNHFEGNAQRDGLVECHGELKAIATTLFNVSNNIRWLGSGPR 312
WP_077026235 234 -LPVGGTAVGSGINTHPEFGSRVAAVLAETTEVPFIEAVNHFEGNAQRDGLVECHGQLKAVATTLFNVANNIRWLGSGPR 312
WP_096055039 222 -LAIGGTAVGTGINCHPEFAGKVCRILTEKTGILFYEAHNHFEAQAARDDSVEVAGQLSAIAASLTKIANDIRLLASGPR 300
1KQ7_A       304 CGIGEISIPENQPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMG---GASGNFELNVFRPMVIHNFLQSVRLLADGM 380
WP_012909738 313 CGFYEIQLPDRQPGSSIMPGKVNPVMCESMMQVAARVIGNDATVAFSg--ATGGQFQLNIMMPVMGLATLESVKLLAASC 390
WP_013109128 313 CGFYEVILADLQPGSSIMPGKVNPVMCESLMQVAALVMGNDQTVAISg--ATGGNFQLNIMMPVMGQTTVGSVVVMAGGV 390
WP_013627712 313 CSFYEVQLPDLQPGSSIMPGKVNPVMCESMMQATARVIGNDQTITLSg--MAGGNFQLNIMMPVMGQTTLESISLLSKSC 390
NP_867926    313 CGFYEVKLPTRQPGSSIMPGKVNPVMCESLMQVAARVIGNDTCMTVSg--GCGGNFQLNIMMPVMAHTILESIELLAGGV 390
WP_009511645 301 SGLGELKLPATQPGSSIMPGKVNPVMSEMLVQAAIYTQGLSQVVVIA---GRDGHFELNVTIPLIAQALHESIHILGNAA 377
WP_014436910 324 AGLAELNLPAIQPGSSIMPGKVNPVLCESVIQVACRVIGNDAAIATAnlgGVGSLFELNVAMPVMADAFLESIDLLTNAT 403
WP_075091346 313 CGFYEIKLPDRQPGSSIMPGKVNPVMCESMMQVCARVIGNDGCLTLSg--AAGGNFQLNIMMPVMGQTTLESIMLLTGAT 390
WP_077026235 313 CGFYEVKIPDLQPGSSIMPGKVNPVMCESMMQVCARVMGNDQTISVCg--ATGGQFQLNIMMPVMGQTTLESVRLLANCS 390
WP_096055039 301 SGLQEIRLPATQPGSSIMPGKVNPVMSEMLVQVCIYAQGLAQMVAMC---GRDGHFELNVTIPLIAHSLHEAIHCLANGA 377
1KQ7_A       381 ESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMV 460
WP_012909738 391 RAFVDFCALEMEANPEACEAAVEKSLAMVTSLNPHIGYENAAAMAKKAFKTGKTIRELCREDGVLPESTLREALDPWSMT 470
WP_013109128 391 KAFDDLCAKLMEANPEACEASIEKSLAMVTSLNPYIGYEKAAQLAKEAFKTGKTIRQLCLEQKILSEEQLTEALDPYSMT 470
WP_013627712 391 EAFVDFCVDGMEANEEACEAAVEKSLSMVTSLNPYIGYEKAAQLAKEAFKTGKTIRELCTEQEVLDADTLNKALDPMSMT 470
NP_867926    391 TAFIDFCLDGMEPNEEACEASVEQSLSMCTSLNPLIGYEQAAALAKEAFKSGQTIRELCKEKGILADDVLTEALDPWKMT 470
WP_009511645 378 RQFADACVAGLEADEARCKELVDRSLMLVTALNPHIGYDNAAAVAKEALATGKTLREVVLEKGLLDAATLDAALEPMSMT 457
WP_014436910 404 LVFTEKLLDGLEVNEDRCRELLSRSLMTVTALAPELGYDVCSDLAKEAHRSDRTIKELVLERGLMEESALDEALDAEKMT 483
WP_075091346 391 NAFVEFCAEEMEANEEACVASVEKSLSMVTSLNPHIGYEKASALAKEAFKSGKTIRELCTEQKILPEDVLEAALDPFSMT 470
WP_077026235 391 NAFVEYCLLNMEANTEACEASVEKSLSMVTSLNPHIGYEKASALAKEAFKSGKTIRELCTEQNILPPDVLTEALDPMSMT 470
WP_096055039 378 RVFADQCVHGIEADPERCRELVDRSLMLVTALNPHIGYDAAAAVAKEAFASNKTLREVVLEKGLLDAATLDRALEPMAMT 457
1KQ7_A       461 G 461
WP_012909738 471 E 471
WP_013109128 471 E 471
WP_013627712 471 E 471
NP_867926    471 E 471
WP_009511645 458 K 458
WP_014436910 484 R 484
WP_075091346 471 E 471
WP_077026235 471 E 471
WP_096055039 458 K 458
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