Conserved Protein Domain Family
NhaP

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COG0025: NhaP 
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 439796
Aligned: 913 rows
Threshold Bit Score: 151.271
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_108720117   1 MEI---LVVA-VVGLLTIAFTTSLApRLRIAAPLVLVILGLAV-SliP-AVp---EVtLNPDV-------VLEGILPPLL 64 
WP_015099749   1 Mt----VILGlTAIVLWSLTAHRMA-RWHIGAPMVMVVAGVLL-G--FvVG----DE-FALALntstaefVAEIILAVLL 67 
WP_007088799   1 -MFewvIILFlGTGLLYGLQSRRLQ-RRNISSPMMMVITGALIaL--PlGIwheaPL-APFADrihfatgFSEMTLAIIL 75 
WP_014987179   1 Mfi--aIAATmTVILIWSCLSRTMA-RWKVTAPLAMVVVGAVV-S--WsSD----HW-LTAAIntdtaqrIVEFILALFL 69 
WP_083472263   1 Mt---aLLAAaVAALARSLAAVRLS-RWNLGAPAVMVLVGVLI-G--LaVE----DS-VAAALnttvaqhVAEITLAFLL 68 
WP_013677924   1 Ml---aLVVImLILLVWALVAGRLA-RFSVTMPLAMLVGGIVL-T--AgSD----PV-FIFEVdfqpaehVVEAILAILL 68 
YP_890053      1 Mll--sLIAIsVVLAVWSLLSREMQ-RLRLTAPMVLVLTGMAI-S--FtMK----DH-LGVTLntdsaehIAELILAVLL 69 
WP_066640348   1 Mns-gaLLAItLLPLAWALVARRLR-SSPLTGPLVMAAAGVAL-G--PqGL----DV-LALDVgaaevagPLTVALVVVL 70 
WP_013126041   1 Mia--aILVAtSAFIVWCLLANRME-RWWISAPLVMVLAGGAV-G--IgAH----GA-ITMALnttaaqrAAEIILAVLL 69 
WP_013584384   1 --MsvpLLVIgLALLVWALWSRVFR-KATVNGPIVMTGLGLLG-G--AlLP----IQ-GELFLeskatlfFAEIVLAYLL 69 
WP_108720117  65 YATAVSTPTMDF-RRDFRLIGGMSVLLVAVSAVALGFLFTALIpGLP--LAAGIALGAIVSPTDAVA-TSIVREVGVSPR 140
WP_015099749  68 FVDATEVRGGRLwGNHPGTAARLLLVALPLSLALAALLGSALLpDVP--WPVLLVLGCVVVPIDFAPaEQVVRHRGLSAR 145
WP_007088799  76 FLDSAVLDYRKE-KHAIRLANRLLLIGLPLTIGVTWAFIIGLHpSIG--ILPALILALIVSPTDAALgRPVLENKSVPDP 152
WP_014987179  70 FTDATEVRDGLS-GRRHTGIFRLLFLAFPLSLGAAYLLGFVLLpGVS--WTVLLLIACIVIPIDLVPaQAIVRDLRVPER 146
WP_083472263  69 FVDATEVRGGRLwGNSPGLVTRVLLLAMPVSVVVAMLLGALLIpGLP--WSILLIIACVVVPIDFAPsEQVVRDRRLPAR 146
WP_013677924  69 FVDATEVPGGVL-GREPRRTLRLLLIALPLSLLLTWLAGLALF-GsSggLWLIAVLATIVTPVDLAPaAAFLRDKRVPER 146
YP_890053     70 FVDATDVRGGFL-GAQPKAALRMLFIAMPVGLALSVLLGLWLLpGLP--WAVLLAVACIVVPIDFAPnSALLRDTRIPER 146
WP_066640348  71 FSDAARLDLSTL-RRSGRLAARLLVVGLPLGIVAGALAALGVMpSLT--LAAAVVLAVAVVPTDAALgLAVVEDERVPPA 147
WP_013126041  70 FVDATEVRGSLL-GRYPRLAARGLFIGIPVSLAMTMLVGWFLLpRLG--WSVLLLVACVIAPIDFASaPSLLRDRHVPER 146
WP_013584384  70 FVDALEVRGSMR-SHFTGVPARLLGIGLPLSLLLVLAVGLVLPlGLS--IAVILAIACISVPADFSPeTSLVRDERVPAR 146
WP_108720117 141 ITSVLEGESLLNDATALVLLRSAVAVALVG--QrE-AGQVLGDFVWSVAVAVVIGAVVGRLNLLVRARV------SdASA 211
WP_015099749 146 VRNVLNIEGGYNDGIVTPIFLFAMILAGDLyqE-RtPLEALATVIPFAIKAIVVGFLVGAVLGWLMDVCatagwmT-EQS 223
WP_007088799 153 IRQGINIESGLNDGLVLPIFTAVVLLEADIvgE-Gs-NNWLTEAIIEISVGAGVGLLAGYVIGQIVNHAvttntiL-DRF 229
WP_014987179 147 VRHALNVESGFNDGLVAPIFLFALAAAEASadS-DqALNALGHAVPAVVKSILIGLSIGALAGYCMTFAarkrwtD-ARA 224
WP_083472263 147 VRSVLNVEGGYNDGIISPVFVFAMLVATEGa-A-AmPMDAFTMAVTQAAKALGAGIVIGGAVAWLMHRCdrngwmT-AQS 223
WP_013677924 147 IRALINVESGLNDGIVAPIFLFTLAAATAAg-G-EsLAETAVEAVPSLAIAVVAGGAVGWVAAQLLRRAldarwtQ-GSA 223
YP_890053    147 VRGLLNVEAGYNDGIVSPVFIFALVLAADSehA-StPMEALGAAVPEAVKALIAGVVVGAGLALAANAAerrdfmT-AQA 224
WP_066640348 148 VRQGLNVESGLNDGIAVPLFVLAVAGAAGElsT---VPEAVTTFLTVIGVAVVTGGVVGAVGVRLLELSdragwsS-ASW 223
WP_013126041 147 VRDVLTVESGYTDGLVTPVFLFALLWADPAndS-DdPIAALVNAAPSSLTALAVGVVMGLVVETGLVRSdaagwsT-ERS 224
WP_013584384 147 VRRWLSIESGYNDGLVSPFLLGAVAFASAg-tT-SdAGRAFAVAAPAGLIAVVVGAVAGTAIGGAIRFAdrrgwtE-PQS 223
WP_108720117 212 NTVLSFAVPFLASVPATLLNSSGLVAAVVAGLVTGHGAVHHi------RP--------AHRAAEAVSWRTISLVLEGSVF 277
WP_015099749 224 RRILVLVVPLLTFFTTVAVGGNGFVASFVSGIAFRFAHRVFia---rkARqrgtaealARSRHDFHLLEDVSAQLGMTMW 300
WP_007088799 230 ERLLGVLSALFIFFLSEKLGGNGFVAAFAGGLALNIFSEK-------------------VRETIESFGEAESELLTMLTF 290
WP_014987179 225 VRIGTIAIPVLTYSVAVWLDGNGFVAAFLAGIAYSTTRHEL-------------------PGEPLQSTEDVAEFSGLAMW 285
WP_083472263 224 RRIAVLLTPLVAYCAAVAIDGNGFVTAFVCGIAFRYLHRLLiarslhrAPatqrphapTALTQDFGLLEDVTALMTMTMW 303
WP_013677924 224 LRIGVLALPLLAYGTAMELGGNGFVAAFVAGVLFEPAARRL-------------------PAGTLHLVEDVGELLSLALW 284
YP_890053    225 KRMILVAAPLLSFGASLAIGGNGFVAAFVCGIAFNYFRRS------------------EQFHTELELVDDVGFLMTALMW 286
WP_066640348 224 RSVATVLLAPAAYALADVLGGSGFVAAFVAGMALAATARG-------------------PVEELTRGSEAVGHLLTLLAF 284
WP_013126041 225 RRLALVATPLVTYAAAVGLGGNGFVAAFVCGIVYRFRRGSA-------------------ANSEVGLTEDVGSLLTAAMW 285
WP_013584384 224 MRIAFIAAPLIVFGLALLLQGNGFVAVFVAGVAVRLTr----------GTd-------ALAAAEIALLDDLSWLLNLLLW 286
WP_108720117 278 LLMGLEMTAIVADLggsslavtG--LWVAFVGLVAVLGVRLVYVTAVLvsLnrrqrrsgdlrerltaidsrlteleeaaa 355
WP_015099749 301 LVVGMCAVLIMSWGf---------sWQALLFALAALTLVRAVPVLLVL--I----------------------------- 340
WP_007088799 291 FIFGLVVIPAVYQLw---------tWEMLIFSIVSLAILRPLCVWICM--I----------------------------- 330
WP_014987179 286 FIVGNVAAATLS-Wl---------sWQVIVYGLLALTLVRLVPVALSL--L----------------------------- 324
WP_083472263 304 FVVGLAAVVMFAVGv---------sWQAIVFCAAALTVVRIVPVIASL--T----------------------------- 343
WP_013677924 285 FIFGAIVNQTLARG--------AitWQVVVFALLALTVLRVAPVVVSL--T----------------------------- 325
YP_890053    287 FVFGLTAVLALGSGv---------pLGLVAFCLLALTVVRIVPVLLAL--L----------------------------- 326
WP_066640348 285 LLFGAAVLSPALERi---------tWPMLAFAVLALTLTRLVPVAIAL--L----------------------------- 324
WP_013126041 286 FVFGAVTVIALADGl---------pWQVLAFAAIALTVLRVLPEAVAV--T----------------------------- 325
WP_013584384 287 LAFGFASIVLLSET--------YdwWPAIVLALVALTVGRFLPVLLSL--V----------------------------- 327
WP_108720117 356 repheddrhrrgprsfasmrlrvtrkqydldyfdAAPFGWREGGVLTWAGMRGVVTVVAAQTLPt---SVPHRSLLVFVA 432
WP_015099749 341 ----------------------------------GTRFTGRERLLVAALGPRGTTSIVFGLLAFnglpDGPAADTILVVT 386
WP_007088799 331 ----------------------------------GSPYSLAEKLYVGWFGPRGIASVIYLLIMItm-idPKGYESLIAAA 375
WP_014987179 325 ----------------------------------GSPFTRRERLMIGLLGPRGVASIVFALLAFnglrNDDDAFLVIGVT 370
WP_083472263 344 ----------------------------------RSSLPWRDRLLLSLLGPRGTTTIVFGLIAYnglpEGDAADTVLLTT 389
WP_013677924 326 ----------------------------------GTDIARRDRVVIGWVGPRGVATLVFGMLAFve-lHGPQAELVLAVT 370
YP_890053    327 ----------------------------------FSPVSWPERLLLGWLGPRGTTSIVFGLLAFna-lDGVAESTVAMVL 371
WP_066640348 325 ----------------------------------GARYSLPTVLFVGWFGPRGLASVIFAAELVdr-aeFAQAEVVATAI 369
WP_013126041 326 ----------------------------------GSGLPRSEVLALGWLRPRGTSTIVFALIAFntlpDGDAADLILTLA 371
WP_013584384 328 ----------------------------------GTEATPKERLFVAAMGPRGAASIVFGLIAAna-lPGEEGFLVLAAT 372
WP_108720117 433 FVVAASSLLLQGGTLGLVVRLLRpA-RVSP--E--DlA---AeNErl--dRHLRA 477
WP_015099749 387 VMCVLSSVVLHGLGFPLLARWsA-RgAAPAp----D-Ar---------------- 419
WP_007088799 376 VMIVAISVTAHGLSAAPLSNMLV-RhLAKKg-A--R-S----------------- 408
WP_014987179 371 LVVVVGSVILHGIGAPLIAERLG-KrRRDKgiA--G-----GhN----------- 406
WP_083472263 390 VLCVLGSVVLHGGGSNLAISRLT-RaK---------------------------- 415
WP_013677924 371 VVTIVASVAVHGLSTGWVARRYP-PvAPAAp-GgpS-AdalPtE---------TS 413
YP_890053    372 VVSVLGSVVLHGVGAPAAARAYQ-RqQTKl-sS---------------------- 402
WP_066640348 370 ITTVALSVVAHGVTAAPWARRYA-AvARRHp-G--D-Ap---eHEdvmvvRSGRT 416
WP_013126041 372 TLVVLGSIVLHTVGAPVAVAGHD-RrVRRRa-G--D------------------- 403
WP_013584384 373 CMVVLGSVILHGIAGPLLVRRLW-PaRARTp------------------------ 402
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