Conserved Protein Domain Family
DUF423

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pfam04241: DUF423 
Protein of unknown function (DUF423)
This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.
Statistics
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PSSM-Id: 461234
Aligned: 340 rows
Threshold Bit Score: 35.1873
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Plim_0328   20 TGAFAAHSLT-DhfavvyagqtrevageviplarKYLQD-FKTGAEYQMFHGLALLAVGIWAlvkqqSgqtasRLLNWA- 96 
CCB64589        33 LSAAAAHKVDsp---------------------------vLATAATVLTLHAAAAVGIFAVA-----IrsacpKLWSAA- 79 
BAF86298        22 LAAVSAHLTGga---------------------------sLAIAANFLLFHAAALVALAAVAg----QvahmrAVLLVG- 69 
jgi:Xaut_1480   65 SAAAAAHVGGga---------------------------nLETAAHFLLFHAAALVGLGALSl----LlgrgrVVLQLG- 112
CBS90037        22 AGAYASHGLAgq----------------------pQAQEwFRTAGLYQMAHALALVLLVALAgr-lgGraggqLALRVA- 77 
WP_014198448    22 AGAYASHGLAgd----------------------pRGQElFRLAGQYQMWHALALIALVALLr---tAdgparLALRLS- 75  Azospirillum
WP_012567112    23 CGAYASHGLPavr-------------------darAVEL-WQTASQYQLAHAAALLGLVAWR-----RhggadRLTALA- 76  Rhodospirillu...
Q0BVT8          19 MAAIAAHALPdP----------------------DTIRL-VQTAVQMQGWHAIMMIISALLAt---hLhtkagRKIALAa 72  Granulibacter...
Q2RPE3          20 SGAFAAHALSalg-------------------dahGVGL-MEKSARYQMYGAFALVVCAWLA-----ErgvggRLVAVA- 73  Rhodospirillu...
jgi:Bresu_2292   5 VGAFAAHGAGp------------------------qIKTlLQTGASYQLAHAVLGVVCAGLap--------riRLTGLA- 51 
jgi:Plim_0328   97 GWMFLVGVILFSGSLYTL---TLSGVRVLGA----VTPLGG 130
CCB64589        80 ALLMLLAASVFTGEIAFH---TFTDNASFRF----LAPIGG 113
BAF86298        70 ASALALGALLFSGDLTLR---ALMEIKLLGG----SAPFGG 103
jgi:Xaut_1480  113 ASAIALGALLFSGDLASR---ALMEVKLLGG----SAPFGG 146
CBS90037        78 GWLFCAGILLFCGTLYAL---ATVGPlpVPM----TAPAGG 111
WP_014198448    76 GWLFVAGIVLFSGTLYAT---ATSGPlsFAM----TAPTGG 109 Azospirillum
WP_012567112    77 GAAFALGCLLFPGALYLL---GWFGPSALGA----VAPVGG 110 Rhodospirillum centenum
Q0BVT8          73 GGAFFVGTVLFCGDLYVL---ALQGI-SLSP----LAPIGG 105 Granulibacter bethesdensis CGDNIH1
Q2RPE3          74 GWLHLAGVVLFCGALSAI---AL-----LGWpagpVAPLGG 106 Rhodospirillum rubrum ATCC 11170
jgi:Bresu_2292  52 GWLSVCGGLIFCLALAFIgllSL---PPFGA----VAPIGG 85 
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