5ZWN


Conserved Protein Domain Family
LUC7

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pfam03194: LUC7 
LUC7 N_terminus
This family contains the N terminal region of several LUC7 protein homologs and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein with a role in splice site recognition. The family also contains human and mouse LUC7 like (LUC7L) proteins and human cisplatin resistance-associated overexpressed protein (CROP).
Statistics
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PSSM-Id: 460842
Aligned: 59 rows
Threshold Bit Score: 205.141
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ZWN_Y         9 AEQRKLVEQLMGRDFSFRHNRYSHQkrdlGLHDPKICKSYLVGECPYDLFQGtkqslGKCPQMHLTKHKIQYEREvKQGK 88  Saccharomyces c...
Q4UEL9         2 DQIRATLAELMGKYEQKEDLDSTK-----PFTDPDVCRQYLTGICPHDLFENtkfymGECSRIHSEKLRERYQNErKNHF 76  Theileria annulata
XP_003385476   5 DQMSKMLDQLMGQNRDGNDKNKER-----RFSDSDVCRPFLLGICINELFINtreemGDCNKIHSIALKNEYERAqQRRD 79 
EKC30213       5 EQMRAMLDELMGTSRDGENSKYKV-----KFDDPRVCKSFLLGCCPHDILSStrmdlGECPKIHDLALRADYEQAsKRKD 79 
ELW68829       5 AQMRAMLDQLMGTSRDGDTTRQRI-----KFSDDRVCKSHLLNCCPHDVLSGtrmdlGECLKVHDLALRADYEIAsKEQD 79 
EFX86367       5 DQMRAMLDQLMGTTRDGESSRYNV-----KFSDPKVCKSFLLGCCPHEILAStrmdiGECVNIHDLALRADYEKAsETKD 79 
BAH70989       5 DQMRAMLDQLMGTGRNGETSRYQV-----QFNDPKVCKSFLLYCCPHDILAStrmdiGECPKIHDNALRADFEKAqQKFD 79 
EFN73235       5 DQMRAMLDQLMGTGRNGENNKFQV-----KYSDSKVCKSFLLACCPHEILSStrmdlGECPQIHDLALRADYEAAqKKRD 79 
EDW41893       5 DQMRAMLDQLMGTTRNGDER--QL-----KFSDPRVCKSFLLDCCPHDILAStrmdlGECPKVHDLAFRADYESAaKTRD 77 
4_pfamImport   1 DAQRALLDSLMGFNRDGDRPDEEAL----DFRHPRVCKSYLCGLCPRELFQHtrldaGACDLLHVPALRSAFLLHqKQEK 76 
5ZWN_Y        89 -------Tf--PEFEREYLAILSRFVNECNGQISVALQNLKHTAEERmkiQQV-TEELDVLDVRIGLMGQEIDSLIRADE 158 Saccharomyces c...
Q4UEL9        77 -----------YGYELETLKIIQPMIDDCDKKIARGKARVEEDLVRRktlDPMiIEEAKKIDSQIQSRMARADELGRNGE 145 Theileria annulata
XP_003385476  80 -----------YHYEEEVLEYLQSFIKENERKIETNKKRIENVEEDTvqqKL--AQEIHECAVLIGEKVTKSEALGSEGN 146
EKC30213      80 -----------YYYDIDAMEHLSSFIADCDRKTELAKRRLKETQEELseeANGkAEMIHKLGEEMGTKLAKAEDLGAEGL 148
ELW68829      80 -----------FFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEIsaeVAAkAERVHELNEEIGKLLAKVEQLGAEGN 148
EFX86367      80 -----------YGYQVDAMDHLTTFVGECDRKTEAAKKRLAETQEELsaeVAAkAQKVHLLAEQIGQKLAKAEQLGAEGF 148
BAH70989      80 -----------HYYDVDATEHLQAFISDCDRRTEAARKRLLETQEELtaeVAEkANAVHELAEKIGQTLAKAEELGAQGL 148
EFN73235      80 -----------HFYDIDAMEHLQNFIADCDRRTEQAKQRLAETQEELsaeVAAkANSVHVLAEEIGKKLAKAEQLGEEGF 148
EDW41893      78 -----------YYYDIEAMEHLQAFIADCDRRTDSAKQRLKETQEELtaeVAEkANAVHGLAEEIGKKLAKAEALGEAGE 146
4_pfamImport  77 denrngyTyesFGYKRELANELSKLLVDVEKKIARAQKRLDEDGDESq-----dKAQILQLTQEMQDVAVQAEQATRDGL 151
5ZWN_Y       159 VSMGMLQSVKLQELISKRKEVAkrv---rniTENVGQSAQQKLQVCEVCGAYLSRLDTDRRLADHFLGKIHLGYVKMRED 235 Saccharomyces c...
Q4UEL9       146 VEESFKIVEEVELLKRTKLEML---------EKGGDASYQSRLKPCDVCGALLSATDSDRRLTEHYSGKIHVGFQKLRDM 216 Theileria annulata
XP_003385476 147 IDESLLVLQQVEEIKLKKKKLEdey----hsHLPRHAQQQQKLRACEVCGAFLSMYDNDRRLADHFGGKLHMGFVQIREK 222
EKC30213     149 VVESLQLMEEVENLKKQKAAAEqey----rnSMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFGGKLHLGFITIREK 224
ELW68829     149 VEESQKVMDEVEKARAKKREAEevy----rnSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREK 224
EFX86367     149 VDESMKMMEEVEEFRKKKATAEqey----rnAMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFGGKLHLGFIKIREK 224
BAH70989     149 VDDSLKLMGEIEDLRKKKSEAEdty----rnSMPVSSYQQQKLRVCDVCSAYLGIHDNDRRLADHFGGKLHLGFIKIREK 224
EFN73235     149 VEESMKLMGEIDELRKKKNEAEqey----rnSMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFGGKLHLGFIKIREK 224
EDW41893     147 VEDSMELMKEIEELRAKKIKAEhey----rtSMPASTYQQQKLRVCEVCSAYLGIHDNDIRLADHFGGKLHLGFLTIREK 222
4_pfamImport 152 VDKSLQLMEQVELLKKKRRELLrqstsaacgIAMSVDNVNQKLRVCDVCGAFLSIFDSERRLADHFGGKVHVGYVQIRNK 231
5ZWN_Y       236 YDRLM------KNNRTTNASKT 251 Saccharomyces cerevisiae S288C
Q4UEL9       217 SKTLSayiqenRHRLNGRgrng 238 Theileria annulata
XP_003385476 223 MESLEeiiakkKERLEKEREER 244
EKC30213     225 LEELKksiadrRMQREKEREEQ 246
ELW68829     225 LEELKrvvaekQEKRNQERLKR 246
EFX86367     225 LAELQvkveerRRQRHTQPVAD 246
BAH70989     225 LSELEknyeerHEARRKFDeqe 246
EFN73235     225 LAELQktveerRKEKRESMLDR 246
EDW41893     223 LIELEktaaprKAELKRTgkmt 244
4_pfamImport 232 LKEVMetmraeRKHEVGKRRMS 253
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