7RNN_D               21 FASSSTLHGLAH-IFSyERLSLK---RALWALCFLGSLAVLLCVCTERVQYYFHYHHVTKLDeVA--ASQLTFPAVTFCN 94 
XP_002003906          9 YFDTCCIHGFRY-L-V-KSV-LIlleRIFWLLLLIVSVYFCIISCISSVERFHTKSTHIGLErNSy-YWNTSMPGLTICP 83 
XP_002051142          2 L------------L------FLE---RLLWFILLIASIYFCIISCLSSVHRFHTKSTHIGLErNSy-YWNTSMPSITICP 59 
WGS:AAPP:GF13151-PA  18 VCQASSIHGMPYaARR-DLHWSE---RLFWLAMVVVATYYAVDTCLAQWQRFRNNPIVYEYE-YLsgLRNFTFLGLTLCT 92 
XP_001987619         33 VCKESSVHGMPYvARR-DLHGLE---RIFWLAMVIGAAYYAGSTCYSQWERYRNHPIVYVYE-YLfaLRSFSLVGVTVCT 107
XP_002059390         25 LSKESAIHGMPYvARK-DLHWIE---RIFWLAMIVAAAYYAIGSCLSQWQRFRDNPIVYEYE-YLfaLRSFPFMGVTLCT 99 
NP_995766            17 LCQESSIHGMPYiARR-DLHWAE---RLFWTFIILGSAYYAISSCLNQWYRFRDNPIVYEYE-YLfgLRIFPFVGITLCP 91 
XP_002059884         45 AGDETSLLAIRLtVNR-GLHMAE---RLLWFLVILGSVFAVYMLSEVQIARYLTSPTVISVDrDYr-GWNGSLPAVTLCY 119
AJC98568             21 LLTTTSAHGIGH-V-V-QEG-LHfieRIIWLSCIFIGVYGMVALSQRIWNRFQTSPTVISMDrNMy-FWNTSFPSLTICS 95  Anophele...
NP_611622           154 FLQGSSIHGFIY-L-A-KLG-LSfveRVLWLAFICVALFSIISLSKRTWHRFQTSPMVISMDrNKl-VWNTSFPSLTVCP 228 fruit fly

7RNN_D               95 LNEF------RFSQVSKNdlyhAGELLALLNNRYEIPDTQMADEKQLEILQDKANFR----------------------- 145
XP_002003906         84 MQRLnq---sLfn--------nYCRANKV----------KGTDKTEFWDFLENLANSty--------------------- 121
XP_002051142         60 MRRInetlfdKYCRVNKLrg-----------------reKTEFWDFLENLANSTYTN----------------------- 99 
WGS:AAPP:GF13151-PA  93 N---------YEtp-------eQVDMLTKIIWGINPEEDPDKGAYYEKFLYVLNRLEytnldtlkpfen------dtsld 150
XP_001987619        108 R---------FIql-------nKTDKLINDIWGVDAAVDIKKAEYYHSFLNVLNHLDyrnldtlmpyvnd----tslkhi 167
XP_002059390        100 Q---------FVTmd------aKISGDLVHNTWNIGSGSTEDEDERINYYRKFLLVVnrlhynnletlapyendttleni 164
NP_995766            92 R---------YHde-------tEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGLRystletlepfen------dttld 149
XP_002059884        120 YDHI------DSFKANKLiq-----------------eaWNVSIIDEDYFYIMDFLYav--------------------- 155
AJC98568             96 HRRIde---dKla--------dYIRMRGF----------DEDDAEQFREFIVLLAN------------------------ 130 Anophele...
NP_611622           229 HKRIde---lKve--------eYILAHPDQ---------FLSEEDQEDFRDFIVKLA----------------------- 265 fruit fly

7RNN_D              146 ------SFKPKPFNMREFYDRAGH----DIRDMLLSCHF-RGe---------vCs---------aE-DFKVVFTRYGKCY 195
XP_002003906        122 ----tnFENIPDYDSIDHTLDQLGikpkHYMELIYNLTFdGTye-------piEklrircvdgqlHlKTRQILTEFGLCY 190
XP_002051142        100 ------FQNIPEYDSIDGTLDSLGirpkHYMELIYNLTY-DGtyepieairirCvdg------qiHmRARQILTEFGLCY 166
WGS:AAPP:GF13151-PA 151 nldyvdMIFKLQSKVLPPPWPTLL---------------------------------------------APIITEVGLCQ 185
XP_001987619        168 nfvdilLSLQEDIMPNPNDQPVDY---------------------------------------------VPTLTEMGLCQ 202
XP_002059390        165 nfvellFNILHRVLPAANQSLPEL---------------------------------------------APTLTEMGLCQ 199
NP_995766           150 nvnylnILLTLQKKVIAVKIPPEL---------------------------------------------APIITEVGLCQ 184
XP_002059884        156 -----vNATASNYAELTKFASDERfdqiDLYDIIQTINRpFEq---------vIssfd----anfKvHVQMVMTERGSCY 217
AJC98568            131 -------VTYTTFLDLPMYKTFGIag-yEYMELLYNLSW--Sfq-------pqVnsg-----tasVlSVQPTITELGLCL 188 Anophele...
NP_611622           266 ------SLTYDNLETLPLNKSYGIps-tKYLELLYELKW--Afe-------peIssg-----aavKmFIYETQTEFGICH 324 fruit fly

7RNN_D              196 TFNsgr-------------------dgrPR--LKtm-kGGTGNGLEIM--------------LD---------------- 223
XP_002003906        191 LCSsylgeeyssrylifgeypefnkylnKHrfVLvkkaTFFDKDVGFN--------------Lmg--------------- 241
XP_002051142        167 LCSs---------------------------------yLGEEYSSRFL--------------IFgeypefnkylnlhrfi 199
WGS:AAPP:GF13151-PA 186 TTS----------------------------------------QLFHFgnpdan--nfnvtpVRqcgffn------dcqf 217
XP_001987619        203 TTT----------------------------------------QLSHLgnpygeskeltgpkVRicdsfa------ncqi 236
XP_002059390        200 TTS----------------------------------------QLVKFgnpygsnvklqvppVRlcnafa------ncqt 233
NP_995766           185 TSS----------------------------------------QLNRYgnpygkletqdmepMKqcgyls------ncit 218
XP_002059884        218 AINspm------------------------saVLgk-kPVQYEQLQEP--------------LT---------------- 242
AJC98568            189 AVNsriavynsyeyw--qsrrwervhepAPlvV-----HPLDGEVYGQ--------------Lik--------------- 232 Anophele...
NP_611622           325 SVNsmvarynsfdyw--rsgdwslmdhgDRvtV-----HPLDGEIYAQ--------------Iin--------------- 368 fruit fly

7RNN_D              224 -IQ------QDE-YLPVWgetdetSf------EAGIKVQIHS------QDEPPfiDQLG-F---GVAPGFQTFVACQEQR 279
XP_002003906        242 ------------------------------fdTDAIDSYIHS------AFEVMkvDNNFgY---SLEGAAY---EPEVEE 279
XP_002051142        200 dVK------QATfFDSDM------GftllgfeCEAIDSYIHS------AFEVMkvDNNF-G---YTHDGATYEPEVEE-- 255
WGS:AAPP:GF13151-PA 218 mHKpfnsifTH------------------------VYMYLHDvnemmlPHDSR-------TltfNAKTKSSYVLKL-LVN 265
XP_001987619        237 tFKppidetL-------------------------VFLYLHDiyevmlPHDRR-------TvvfHMGTEYSYVLKV-LLN 283
XP_002059390        234 tIKpavpgtH-------------------------VHLFMHDvnevmmPKDRR-------TvsiDTGNETSYLLKV-LLS 280
NP_995766           219 sLKpinsivAP------------------------IFMYLHDveemmlPDDMR-------TpsfDAKDIESKDLDI-MLH 266
XP_002059884        243 -CQy----gKQQcYISMD------Ly------ESTGVLDVHS------PYEVSatEANI-V---ALHKSDEITASFKV-- 293
AJC98568            233 ------------------------------leS-SYEVFFHG------SMEVAeiSKRQ-Y---SFQESYYTTVELLALE 271 Anophele...
NP_611622           369 ------------------------------lsT-AYDVYFHG------AGDVPsiSKQR-Y---TFPESDYTTVELIALE 407 fruit fly

7RNN_D              280 LIYL------------P-PPWGT--Ckavt----mdsD-LDFfdSYSITACRIDCETRYLVENCNCRMVHMP-GD----- 333
XP_002003906        280 IIAEpnfet--etsisQr------kCrfy-----hesN-LTHypFYTKNICQQECRINLAYKICKCIPHFYPnRIa---- 341
XP_002051142        256 -IVAesn-------frTeTSISQrnCrfy-----hesN-LTHypFYTKNICQQECRINLAYKICKCIPHFYPnQIanpk- 320
WGS:AAPP:GF13151-PA 266 SLSAdgevrnlpvayrK--------CryhdennlqyyS------PYHPSLCRLECRIDWALTLCKCKPYFYAaGPkt--- 328
XP_001987619        284 PISAeedvrqvpiayrK--------CrykdenylkyfS------DYSPSLCRLECRIKVALKLCNCKPFFYAvPIne--- 346
XP_002059390        281 SISAedevrnvpvayrK--------CryieennlkyyS------PYHPSLCRLECRINVALDLCKCKPFFYAaGPkk--- 343
NP_995766           267 TTSAesevrnlpvayrK--------CrfsdennlqyyS------PYHPSLCRLECRIKWALSLCNCKPYFYVaAPev--- 329
XP_002059884        294 -LETvas------knlReLSVEQrkCvfn-----deeTsNLK--IYSKSLCLARCRAIMALEMCNCVPFFYPfVEgps-- 357
AJC98568            272 ILTSsnare---lsisQr------qCrft-----hedEmLLFspVYSYNLCRIECRMKFAFKLCGCVPHFYRpVGkg--- 334 Anophele...
NP_611622           408 IFTNeear-----atkQr------sCrfn-----yeaEeMMTvpIYSFGLCLSECRMFFALRVCGCVPHFYRnRCgynhi 471 fruit fly

7RNN_D              334 ------APYc----TPEQYKeCA------DpALDFL--------VEkdqeyCVCEMPCNLTRYGK-ELS---MV-----K 380
XP_002003906        342 ------KPKpv--cTYKTLKsCF------PrHAGYFlkfyeengNHekptgCYCEQNCIDAVIKL-KSAl-aMR-----G 400
XP_002051142        321 --pvcnYKT---------LKsCF------PrHASYFlkfykkdgNRaesaeCYCEQNCIDAILKL-KRA----------- 371
WGS:AAPP:GF13151-PA 329 ----piCTI-----SGML---CLars-nwLak------------------pCECFPLCKESTYSL-IEEyeqSGgdqsyV 376
XP_001987619        347 ----rtCNI-----EDMI---CLtqh-kwLdk------------------pCDCQPLCRENTYII-TEKqgqSGngeqyA 394
XP_002059390        344 ----aiCSV-----KGML---CLars-nwLer------------------tCDCLPLCKENSFIV-AEElgqSGggtqyA 391
NP_995766           330 ----piCTV-----SGML---CLars-kwLer------------------pCDCYPSCREETFTI-FKVsdqTGgddnyS 377
XP_002059884        358 ----cnPAG---------FE-CL------L----DFkwpi-walHI-----CKCPSTCTEIEYTMqTMK---KS-----S 399
AJC98568            335 -----nFRYri--cDFEGLR-CLgqragkGtHEMITl------rSKknpidCNCLPNCDDSNFFI-QAYvriCR-----R 394 Anophele...
NP_611622           472 fgtqmrNGRrlpvcGLEGIG-CLv----kIkREIISl------kSDkykinCNCLANCDDSNFFV-QSY----------R 529 fruit fly

7RNN_D              381 IPSKAsakyLAkKYnksEQyigEniLVLDIFFEVLNYETI------EQKKAYEIAGLLGDIGGQMGLFIGASILTVLELF 454
XP_002003906        401 SKQLL--------G----S------MGSSVSMSTWPRNQF------KRQVIFSFTDLLVSIGGTAGLYLGFSVLGLVEFI 456
XP_002051142        372 LPMR-----GA-KQl-lGS------MGSSISMNTWPRNQF------KRQVIFSFTDLLVSIGGTAGLYLGFSVLGLVEFV 432
WGS:AAPP:GF13151-PA 377 GEQF---------------------ERTIIIKMDLPKMGM------KRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGLI 429
XP_001987619        395 GANF---------------------ERTIIIQLDLPKMGM------KRRVVFSTDQLLMSLGGAIGLFLGASFMTVFGLI 447
XP_002059390        392 GANF---------------------ERTIIIQQESPKMGM------KRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGIT 444
NP_995766           378 GERF---------------------ERTLIINLQISRMGI------NRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGVV 430
XP_002059884        400 WGMK---------N----N---EeaASVETATSSFRWDLIppkvrfRRDVVFSFEDLIVSFGGVLALFVGVSVMGLVQMG 463
AJC98568            395 SREWF--------L----G------ANLQWGLTDYPKMQL------NRDIIFGLSDVFVYIGGLGGFFLGCSLITFAEFV 450 Anophele...
NP_611622           530 SRVWF--------L----G------ANLQWGILEHPKMQL------RREVLFSFADVLVYIGGLVGFFLGCSALSFTEII 585 fruit fly

7RNN_D              455 DY 456
XP_002003906        457 YF 458
XP_002051142        433 YF 434
WGS:AAPP:GF13151-PA 430 SL 431
XP_001987619        448 QL 449
XP_002059390        445 YV 446
NP_995766           431 YF 432
XP_002059884        464 YV 465
AJC98568            451 FF 452 Anopheles coluzzii
NP_611622           586 YY 587 fruit fly