Conserved Protein Domain Family
cyclophilin_SpCYP2_like
?
cd01922: cyclophilin_SpCYP2_like 
cyclophilin_SpCYP2_like: cyclophilin 2-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to Schizosaccharomyces pombe cyp-2. These proteins bind their respective SNW chromatin binding protein in autologous systems, in a CsA independent manner indicating interaction with a surface outside the PPIase active site. SNW proteins play a basic and broad range role in signaling.
Links
?
Statistics
?
PSSM-Id: 238903
Aligned: 5 rows
Threshold Bit Score: 290.975
Created: 5-Oct-2004
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
Conserved Features/SitesClick to see Conserved Features Help
 
active site
Feature 1:active site [active site]
Evidence:
  • Comment:Based on similarity to related proteins with known structure and function.
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                            ##    #                                  
Q9NI62      7 TLQTTVGDITLELYYNHAPKACKNFYELSKRGYYDNTIFHRLIKDFMIQGGDPLGNGRGGESIYGKKFEDEItkeLKHTG 86  Dictyostelium disc...
Q9Y3C6     15 YLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELhpdLKFTG 94  human
AAH51602   17 LVETSMGTITVELYWLHAPVTCKNFAELARRGYYNGTKFHRLIKDFMAQGGDPTGTGRGGASIYGKQFEDEIhpdLKFTG 96  African clawed frog
NP_501118  13 ILDTTMGKIALELYWNHAPRTCQNFSQLAKRNYYNGTIFHRIIADFMIQGGDPTGTGRGGASIYGDKFSDEIderLKHTG 92  nematode
NP_703628  50 TIYTNLGEFQVELYWYHSPKTCLNFYTLCTMGYYDNTIFHRVIPDYIIQGGDPTGTGKGGKSIYGEYFEDEInteLKHTG 129 Plasmodium falcipa...

Feature 1                     # #       #                                          
Q9NI62     87 AGILSMANSGvnsNGSQFFITFGPTPWLDGKHTIFGRVks--gMKVVQKMnamqtn-ndkpidEIRIIK 152 Dictyostelium discoideum
Q9Y3C6     95 AGILAMANAGpdtNGSQFFVTLAPTQWLDGKHTIFGRVcqgigMVNRVGMvetnsq--drpvdDVKIIK 161 human
AAH51602   97 AGILAMANAGpdsNGSQFFLTLAPTPWLDGKHSIFGRVshglgTLNRLGMvetdsq--drpldEVQVLR 163 African clawed frog
NP_501118  93 AGILSMANAGpntNGSQFFITLAPTQHLDGKHTIFGRVaa--gMKVIANMgrvdtdnhdrpkiEIRILK 159 nematode
NP_703628 130 AGILSMSNNGpntNGSQFFITLCPLPHLDGKHTIFARVsk--nMTCIENIasvqttatnkpifDVKILR 196 Plasmodium falciparum 3D7

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap