Conserved Protein Domain Family
CAAP1

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pfam15335: CAAP1 
Caspase activity and apoptosis inhibitor 1
CAAP1, or caspase activity and apoptosis inhibitor 1, is a family of eukaryotic proteins involved in the regulation of apoptosis. It modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.
Statistics
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PSSM-Id: 464655
Aligned: 25 rows
Threshold Bit Score: 69.1572
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001313632  64 FKPISGYMQERREMLEQCFSVLGENKLQEMLPDGLKDCSLNEIKKLCWDQLLQISDIHLLEIL 126
XP_001952454  46 LFPLSHYANDPEQLIQQLFSVVRGKRLTRLIPPELKDMTFEELKADCLIQLLCMSKKRVLATL 108
XP_004924188  25 EHDLAYYIHDRVELMHQIFSVLKPKELKAMAPDCVRNVSIDDLQELCTEELLGISSKRLLAIL 87 
Q16N62        32 IKPLGAFVDDRVELIRQAFTCLKPKEIKCLVPDFLQGKSIEFLQEQCLDEVLGISTKRLLSII 94  yellow fever mosquito
Q5TXA3        70 LKPLSAYVDDRLELIRQVFSCVKPKEIKYLLPDFLEGKSNDVIKERCLDELLGISTKRLHSII 132 Anopheles gambiae str. PEST
3_pfamImport   1 LHPLTFYIDDRVELIKQVFASLKPKTIKNLSPNFLKKQTLEEIEEKCLNELLGISSKRLRSII 63 
XP_002026503  32 LHPISHYIDDRLELVKQIFGTLKPKTIMNLAPEFLKKNSLDEIEELCLEELLCLSTKRLKSII 94 
XP_019855178  15 PRGLDAYFDDRLSLLDQLFTILTQQDIHGLLPDILKGLKMKKIKELCLKELEKLDNDQLLSII 77 
XP_015795508  21 IEPLSRLINEPEKLIDEVFKIAAQYLPKDIVPASLKDIPTVELKKLCLEQLKKVEHQTLLNIL 83 
EEC20106       3 WYDLSAFVDQREQLLEESFQALSPDELGILTPVELQHIPMGELKALCLDELRKLPNERVLAIL 65 
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