1BAI,1W5V,3NR6


Conserved Protein Domain Family
RVP
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pfam00077: RVP 
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Retroviral aspartyl protease
Single domain aspartyl proteases from retroviruses, retrotransposons, and badnaviruses (plant dsDNA viruses). These proteases are generally part of a larger polyprotein; usually pol, more rarely gag. Retroviral proteases appear to be homologous to a single domain of the two-domain eukaryotic aspartyl proteases such as pepsins, cathepsins, and renins (pfam00026).
Links
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Statistics
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PSSM-Id: 425454
Aligned: 11 rows
Threshold Bit Score: 102.06
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1BAI_A    9 DRPLVRVILTNTgshpvkqrsvYITALLDTGADDTVISEEDWPTDwpvmeAANPQIHGIGGGI-PVRkSRDMIELGVINR 87  
A1Z651  546 PEPRITLKVGGQ----------PVTFLVDTGAQHSVLTQNPGPLS-----DKSAWVQGATGGK-RYR-WTTDRKVHLATG 608  Xenotropic MuLV-rel...
P04585  495 QRPLVTIKIGGQ----------LKEALLDTGADDTVLEEMSLPGR-----WKPKMIGGIGGFI-KVR-QYDQILIEICGH 557  HIV-1 M:B_HXB2R
Q9IZT2  753 SRPMLHISLNGR----------RFLGLLDTGADKTCIAGRDWPANwp-ihQTESSLQGLGMAC-GVA-RSSQ-PLRWQHE 818  Mouse mammary tumor...
P63120    8 NRPVCKAIIQGK----------QFEGLVDTGADVSIIALNQWPKNwp-kqKAVTGLVGIGTAS-EVY-QSTEILHCLGPD 74   human
Q9TTD4  144 ARPELELRINGK----------LFRGVLDTGADISVISDKYWPTTwp-kqMAISTLQGIGQTT-NPE-QSSSLLTWTDKD 210  sheep
P03353  455 QQPILGVRISVMgqt-----pqPTQALLDTGADLTVIPQTLVPGPv---kLHDTLILGASGQT-NTQ-FKLLQTPLHIFL 524  Human T-lymphotropi...
P19199 1195 YNGLYNVKVGIKpdnm---epyYINAIVDTGATACLIQISAIPENyyedaKVTVNFRSVLGIGtSTQ-MIKAGRILIGEQ 1270 Commelina yellow mo...
P0C776  586 DRPLVRVILTNTgshpvkqrsvYITALLDSGADITIISEEDWPTDwpvmeAANPQIHGIGGGIpMRK-SRDMIEVGVINR 664  Rous sarcoma virus ...
1W5V_A   18 QRPLVTIKIGGQ----------LKEALLDTGADDTVLEEMSLPGRw-----KPKMIGGIGGFI-KVR-QYDQILIEICGH 80  
3NR6_A   21 PEPRITLKVGGQ----------PVTFLVDTGAQHSVLTQNPGPLS-----DKSAWVQGATGGK-RYR-WTTDRKVHLATG 83  

1BAI_A   88 DGSLerPLLLFPlvaM-TPVN------ILGRDCLQGLGLRLT 122 
A1Z651  609 KVTH--SFLHVP---D-CPYP------LLGRDLLTKLKAQIH 638  Xenotropic MuLV-related virus VP62
P04585  558 KAIG--TVLVGP-----TPVN------IIGRNLLTQIGCTLN 586  HIV-1 M:B_HXB2R
Q9IZT2  819 DKSGiiHPFVIP---T-LPFT------LWGRDIMKEIKVRLm 850  Mouse mammary tumor virus (STRAIN C3H)
P63120   75 NQEStvQPMITS-----IPLN------LWGRDLLQQWGAEIT 105  human
Q9TTD4  211 GHTGqfKPYILP---Y-LPVN------LWGRDILSKMGVYLy 242  sheep
P03353  525 PFRR--SPVILS---S-CLLDthnkwtIIGRDALQQCQGLLY 560  Human T-lymphotropic virus 2
P19199 1271 YFRMpvTYVMNM---GlSPGIq----mIIGCSFIRSLEGGLR 1305 Commelina yellow mottle virus
P0C776  665 DGSLerPLLLFP---AvAMVRg----sILGRDCLQGLGLRLT 699  Rous sarcoma virus (strain Schmidt-Ruppin A)
1W5V_A   81 KAIGt--vLVGP---T--PVN------IIGRNLLTQIGCTLN 109 
3NR6_A   84 KVTH--SFLHVP---D-CPYP------LLGRDLLTKLKAQIH 113
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