1R30,4JY8


Conserved Protein Domain Family
BioB

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COG0502: BioB 
Biotin synthase or related enzyme [Coenzyme transport and metabolism]
Biotin synthase or related enzyme is part of the Pathway/BioSystem: Biotin biosynthesis
Statistics
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PSSM-Id: 440268
Aligned: 711 rows
Threshold Bit Score: 152.51
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1R30_A        29 RWTLSQVTELFE-KP----LLDLLFEAQQVhRQHFDP-RQVQVSTLLSIkTGAC--PEDCKYCPQSSRYKtgL-EAERLm 99 
WP_011641070  15 AINEEEALYIFKeTEqeekATELLQTARFV-REKIMG-NTFKWSGGIAR-VLRCnlKPLCQYCPYWRKKG-----DEPL- 85 
WP_012412554  47 QFFQSLFQEILH-Fed-neQQLLFEIARYV-RHKYLE-NKGNLRGVIEI-TNAC--ERSCNYCPMRIENEe-LgDRYNF- 117
WP_012662524  13 ALGPAELTELFY-NAt---TAELATMGNKI-CTQVHG-RNVLLRGLLEY-TNYC--VSNCLYCGIRRENRk-V-QRYRI- 80 
WP_012971169  24 AFA-ESVKTALN-Arg-qaQEALFEIAREA-RLSGFPdRRAEVRSVIEI-SNIC--KQRCNYCNIGCEDT----QKYVI- 91 
WP_013320418  14 QITKTELITLLQ-Asg-slQQQLFRQAREI-RQRYHG-DQVVVRGVIEI-SNYC--QKNCNYCAMRATNQk-L-ERYRL- 83 
WP_009015831  12 SLADEQYLELLR-SQdpslRNKLFAAAQEA-VNYLFH-RRVYMQGVLEF-TNHC--PRNCFYCDLREENRd-K-KRFRL- 82 
WP_058721740   1 MTNQRALIEALR-Arg-teQQNLFAAARQA-RKLSSG-DAITLRGVIEV-TNVC--RVNCDYCPMRRENTr-QnERFQL- 71 
WP_120175917  17 EFSDDDIVRLLG-LTdpeeCEALRQRAFDV-TTEKTG-NNVYLRGLIEV-SNIC--TANCRYCGIRKDNHt-V-ERYTL- 87 
WP_076932227   8 SLNKRDIVSILK-MDtreeMDALQSLAMEV-KQERVN-RIVYFRGLIEF-SNQC--RKNCFYCGLRKGNKg-V-NRFRL- 78 
1R30_A       100 EVEQVLESARKA-KAAGSTRFCMgAAWKNPHErD-MPYLEQMVQGVK-A--MG-----LEACMTLG-TLSESQAQRLANA 168
WP_011641070  86 GIEEILKGVDYI-ARHGLQEFHL-SGGTTLRSd--GSDVLEIVTAIRtAgyND-----MEIDINCGaAMSFDTLKELKQL 156
WP_012412554 118 SSEKILETAIEI-KEAKIPIVFI-QAGEIKAt---TKTVSRAIPKIRqLfeNN-----VIILLNLG-DKPKEDYTILKEA 186
WP_012662524  81 KENRLLEVIQAG-FDRGLRTFVI-QGGEDPCY-P-VERICRLVEAIKqKtrGE-----AAVTLSCG-MRSREEYGEMVQA 150
WP_012971169  92 PSDDLVEIAAFLhHERGRRVLLL-QSGENKDR-RfVANVIRACAQIKdRl-PD-----IQLIGCIG-NLSRDQYRAMREA 162
WP_013320418  84 GVEQIFAIGTHI-KEANIPIIFL-QGGQDPHC---DPILEEVIPRLKkE--LN-----LSVLLCLG-EKPREAYQKFAEL 150
WP_009015831  83 NSEEIRGALKEG-YELGLRSFIL-ESGEDHYY-T-DIIMGNLISTLKgEf-PD-----CALGLSIG-ERSRLSYSRMKKS 151
WP_058721740  72 SEDDIVEMGAAI-VAAGIRVILI-QGGETTT--L-LAVVEAAVRRLMkFhgPK-----LEIIVNLG-NFTSNQYHRLRDA 140
WP_120175917  88 TEESIVACALHA-LHEGYGSIAI-QAGERRDP-KwIAWISRLLERIHkEtvCEelptgLGVTLSLG-EQTYEVYKEWAEA 163
WP_076932227  79 SEEEILKAADFA-HENRYGSLVL-QSGEDQSE-DfTDFVCRVVKQIKsR--YD-----LGITLSCG-EQSEETYHRFFES 147
1R30_A       169 GLD----YYNHNLDTS-PEFYGNIIT-T--RT--YQERLDTLEKVRDAGIKVCSGGIVGLG-----------ET-VKDRA 226
WP_011641070 157 GVK----LVRSVFETInPQVFNKVKP-G--DD--LEEKKKFARLIGEAGLGLGTGIMAGLSp---------nETkYQDYV 218
WP_012412554 187 GAN----QYIIKFETSnWNLHKQARG----YL--LSDRLNRIDDLLSLGYEVGSGTIVGLKavnangkieieQT-PKMLA 255
WP_012662524 151 GAD----RYLIRFETSdPKLHACLRD-G--KT--LKDRLQALEDTRTAGFQTGSGFMLGLPg----------ET-PEVRL 210
WP_012971169 163 GVD----RYLLKIEASnPVLYEAAKP-H--DT--WSERRQCLDDLLELGFMVGSGIIVGLPg----------QT-EDDLV 222
WP_013320418 151 GAD----SYILKFETSsPSLYKNIAH----TP--LLRRLQCIRTLQESGFKVGTGNIVGLPn----------QT-IDSLA 209
WP_009015831 152 GAD----RYLLRFETAdPLHFSRLHPpS--NS--LSTKIDCLNDLKLLGYELDTGFLVGAPy----------EM-AEYLA 212
WP_058721740 141 GVS----SYILKHETSnPELFRQLR--H--ES--LEERLRCLHDLKSLGFKVGTGLISSLPg----------QS-LESIA 199
WP_120175917 164 SGNptglRYLLRIESSnPRLFAELHStPgkHEkiLEHRYQALRDLRRAGYQVGTGVMIGLPg----------QT-LEDLM 232
WP_076932227 148 GAH----RYLLRIETAsPDLYEKWHPeDgkHR--FVTRLNCLKSLKKIGFQVGSGSMVGVPy----------QT-YEDIA 210
1R30_A       227 GLLLQLANLptP-PESVPINMLVKVKGTPLADN------DDVDAFDFIRTIAVARIMMPTSYVRLSAGREQ-MNeqTQAM 298
WP_011641070 219 DFIFYIKHY--EhLKSVYVSKFFPFNGIPMKDH------PSCSDWEAARLVAVMRLVLRDKDIGGAAGWGR--D--NYPT 286
WP_012412554 256 NDLLLAMRK--K-VHMCSASPFVPGKGTPLAQM------SAGNASMTLNWMALARIMMPKVMIPSVSALNVlLGqdGQLK 326
WP_012662524 211 ENILLCQRL--E-LDMVGIGPFIPHPDTPLKHV------KQHPIEDSIRGVALLRLALPQTHIPATTAAGT-LQpdGREQ 280
WP_012971169 223 GDLRFLSEL--D-LDMVSASVFIPGHGTVYEHE------PRGDVETTLNFMALLRILNPNALMPTTSSLEK-LKadGQYL 292
WP_013320418 210 EDILLALEI--Q-PDFVSSSPFIPNQDTPLENL------PYGDINLTLNTMALYRILLPSCLIPTVSALEK-IQkgGQLM 279
WP_009015831 213 RDLTMLQEI--N-PDTISLSPFVPREGTSFRHQ------LPCNLETFLRLTAILRVMFPKANIAASPLVNS-IHvqGQVM 282
WP_058721740 200 EDIRLAGRL--G-VDMCSVSPFIPAPNTPMEHV------PNGDNDLALNAIACLRILYPNILIPSVSALER-TSvgGQSR 269
WP_120175917 233 RDIRTFGEM--G-ADMIGMGPYITSNGADMTALgm--meKRPLMQLALNMISTTRLVMPDINIAAATALET-LEpnGRVR 306
WP_076932227 211 GDILFLRDM--R-VDMMGIGPFIEHSGTPFYRSeaysirQEERLGLTLRMIAILRILLKDVNIASTTAMQV-LDkfGREK 286
1R30_A       299 CFMAGANS----IFYgCK--------LLTT--PN----------PEEDKDLQLFRKLGLN-P 335
WP_011641070 287 PLMAGAGNrvggIHI-NRtp-----hYHVYqnEEylyednmefhNHMESTSKKLKELGVE-V 341
WP_012412554 327 GLQAGANT----ITV-NFtppnyqdqYAIY--SKqkr-----ykVKYEYALDIMEKAGIEpI 376
WP_012662524 281 MIAAGANV----LMP-NItpadfkkdYLLY--PGkicld-esgiHCINDLSSRVRPLDRE-L 333
WP_012971169 293 GLMAGANT----LTVhDGtpqafqhlFPIY--DDtr------yrPNDDHLRAIAERAGLv-V 341
WP_013320418 280 GLNAGANV----LTI-NFtpaqcrdkYAIY--SKqr------fvVSLEHAQQTIKQAGLSsn 328
WP_009015831 283 AIYSGANV----LRV-PLfpppvpgvTRrsgg--------vsllRRLQSLYASLSSHNYE-M 330
WP_058721740 270 GLDAGANV----LTV-NFtklehqrkYLIY--GKdrfvv------ttshVQKIVADAGLH-L 317
WP_120175917 307 GIRHGCNV----IMP-NItpqttrasYQLY--DNkagte-vgpeSNVLVERNIVEMTGRT-L 359
WP_076932227 287 GLLFGANV----IMP-NLtplihrkdYLLY--EDkpcln-edasQCNNCLEARIASVGET-I 339
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