Conserved Protein Domain Family
CoaBC

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COG0452: CoaBC 
Phosphopantothenoylcysteine synthetase/decarboxylase CoaBC [Coenzyme transport and metabolism]
Phosphopantothenoylcysteine synthetase/decarboxylase CoaBC is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Statistics
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PSSM-Id: 440221
Aligned: 744 rows
Threshold Bit Score: 365.888
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010235885   3 ALSGIKVLLVIGGGIAAYKSCELIRLIRKNGGSVTCVLTEGGSHFVTPMTLAALSENPVHTTLWDLRNEVEMGHIQLSRE 82 
WP_065533694   1 MLKGKTVLLGVTGGIACYKSAGLASALVKKGANVQVLMTRNATEFIGPHTFESLTGNRVSVDTFDRNYQFQVEHIALADQ 80 
WP_012799435   1 MLANKTVVVAVCGSISAYKACDLVSQLGKLNCTVRVAMTEAACKIIPELPLEVLSGAHVVTGISPE--DCETVDVWLAE- 77 
WP_106057729   1 MLKDKCVVVGVTGGIAAYKTASLVSALKKERADVHVIMTKNATEFISPLVFETLTGNKCMTDTFDRDFKFDVAHISIAKA 80 
WP_058117506   1 MLKGKTVLLGVTGGIACYKAAELASALVKQHCSVHVLMTAHATEFITPLTFESLTGNRSVVDTFDRNYPHQVEHIALADQ 80 
WP_068759322   1 -MNKKTIVLGVCGGIAAYKSAQLASSLYKKGYDVHVIMTKNATEFITPMTFETLTHNRVSVGTFDRNFQYDVNHISLAKR 79 
WP_111525472   1 MLENKNILLGVTGGIAAYKIANLASMLKKQGANVKVIMTKNACQFITPMTFETLTSEKVYIDTFDRNFEFKVDHIELGKW 80 
WP_106790098   1 MLKDKTILLGVTGGIAAYKSAALASLLIKAGADVRVIMTEHAVNFINPITFETLTGHKCITDTFDRNFEFQVQHISLAQA 80 
WP_013281450   1 MLEGKNILLGVTGGIAAYKSADLASKLIKQHANVDVIMTENATKFITPLTFEALTHNRCVTDTFDRNHPWEVEHIALADK 80 
WP_013064628   1 MLTGKTIVLGVTGGIAAYKSANLASMLIKLHADVHVIMTQNATKFITPMTFETLTNNKCIVDTFDRNFSFDVKHVSLAKR 80 
WP_010235885  83 ADLVVVCPATANMLAKMAAGIADDLATTLLLATDKPVMAVPAMNVRMWSHAAVQANVARLREAGVIVLDPDEGPMACGEY 162
WP_065533694  81 ADLVLVAPATANVLAKLAHGLADDMLTTTVLACDCPKIAAPAMNTRMYENPVTQDNLALLRRYGWEIVEPASGRLACGAV 160
WP_012799435  78 ADAVVVAPASANTIAYVAMGEAPSAAAYAVLNATCPVMVAPAMNVNMYRNVATQENLEMLRSRGYIVIPPVSGHLACGDD 157
WP_106057729  81 ADYFVVAPATANFIAKASYGMADDMLTTTFLAANCPKLVVPAMNTQMFLNPITQGNIMRLFKVGIRVMQPSSGVLACGDV 160
WP_058117506  81 ADLVVIAPATANVLAKLAHGLADDMLTTTVLACDCPKLAAPAMNTRMYENPVTQDNLDLLRRYGWEIMEPASGRLACGAV 160
WP_068759322  80 ADLFVVAPASANCIAKFAHGLADDMLTTTFLAAACPKLIAPAMNTGMLNNPITQHNIEICKKYGMTFVESDSGYLACGDV 159
WP_111525472  81 ADVFLIAPASANVIGKLANGIADDMLTTTTLAMRCPVVVSPAMNTTMFENKVVKHNIMKLRTYGMEIILPASGHLACGDI 160
WP_106790098  81 ADAILVAPATANVIAKLAHGIADDMLTTTILASEAPKIIAPAMNTKMYENPITQDNLAILERYGFTIAAPASGRLACGDV 160
WP_013281450  81 ADALVIAPATANCIAKLAFGIADDMLTTTALACTCPKIIAPAMNTKMYENPVTQRNLNMLRELGYTIVTPGDGYLACGAV 160
WP_013064628  81 GDLFVVAPCTANVIGKLAHGICDDMLTTTMLATRAPKLIAPAMNTGMWENPILQDNLTKLKGYGYHIIDPIIGRLACGDT 160
WP_010235885 163 GAGRLPEPPAIWNAIASWAGQDtgtetreresqgglggliasliprggrkaapqpdtllaekggaaaaapeedrgalyhf 242
WP_065533694 161 GKGKMPEPEELLETVLHALSHA---------------------------------------------------------- 182
WP_012799435 158 GEGKLPSIPELIDWICREIACE---------------------------------------------------------- 179
WP_106057729 161 GVGKMPEPDAILEEILFDLAYA---------------------------------------------------------- 182
WP_058117506 161 GRGKLPDPQVMLESVLHALSHE---------------------------------------------------------- 182
WP_068759322 160 GKGRLAEIEDIEDAIESLLVKD---------------------------------------------------------- 181
WP_111525472 161 GAGKMPEPEMLLEYIKKALYQK---------------------------------------------------------- 182
WP_106790098 161 GAGKMPEPEVLFQYLDMACGHA---------------------------------------------------------- 182
WP_013281450 161 GKGRMEEPANIVEAIIHEIACP---------------------------------------------------------- 182
WP_013064628 161 GTGKMQAEEVIVEHILAFMAKE---------------------------------------------------------- 182
WP_010235885 243 dgAPLAGRHVLVTAGPTHEPIDPVRYIANRSSGKQGFAIAAAAAAAGARVTLVAGPVELATPPGVMRVEVQTARDMAAAV 322
WP_065533694 183 --KDMEGLKVLVTAGPTQEALDPVRCLTNHSTGRMGYAVARAAAARGAEVTLVSGPTALKKPAYVETVDVVSAQDMFEAV 260
WP_012799435 180 --KDLAGKSILVSAGPTREAIDPVRFITNHSTGTMGYAIARRAMLRGADVTLVSGPVSLTPPPFVNVVDITSAQDMFEAV 257
WP_106057729 183 --KDLAGKKVLVTAGATQEAIDPVRYITNHSTGRMGYALAKAAAYRGAQVTLITGKTNLEPIPYVNTIEITTSAEMCEEV 260
WP_058117506 183 --KDMCGLRVLVTAGPTREALDPVRYLTNHSTGRMGYAVARAAAARGASVTLVTGPTELPRPAYMEVVEVTSAREMFQAV 260
WP_068759322 182 --KPLKGMKVVVTAGPTQEDLDPVRFMTNHSSGKMGYAVARAARNLGADVTLVTGPVSLRKPVFMDVVEVRTAIQMFEAV 259
WP_111525472 183 --KDLSGKKVCVSAGPTREAIDPVRYISNNSTGKMGIEIAKMAAYRGAKVSLVMGPSNVLVPDFIKRIDIKSAEDMYEEI 260
WP_106790098 183 --KDMVGKKVLITAGPTRESIDPVRYITNHSSGKMGYSLARACSMRGADVTLVTGPTSLEAPLFTQVVPVTTAREMFEAV 260
WP_013281450 183 --KDMKGLKVMVTAGPTREAIDPVRYITNHSTGKMGVALARAAALRGAMVTLVAGPIDIEVPQYINTVRVNSAKEMFEAV 260
WP_013064628 183 --KDLAGKRYLITAGPTQEAIDPVRYITNHSSGKMGYAIAKMARLRGAQVTLVSGPVNIKPFCGVDVVPVKSAADMFEAV 260
WP_010235885 323 RESLP-ADIAIMAAAVADWRTRDVAESKMKKR--GDa-PPALELAENPDILATLGAsDAr---PGLLIGFAAETDDVVEN 395
WP_065533694 261 TARAPeQDIIIKAAAVADYRPAQVAQDKVKKG--EG--ELSIPLERTRDILAWLGEhRRp---GQFLCGFSMETRDMVEN 333
WP_012799435 258 SSRADdQDAVIMAAAIADYRPADVKGDKIKKA--DG--AFDIDFERTPDTLAWLGAhRNg---RTLLCGFSMETRDVIEN 330
WP_106057729 261 LKHAPkADYIFKAAAVSDYAPVYTSDEKIKKQ--DG--NMVIELRRTSDILAELRKiRKp---EQIICGFSMETQNLLEN 333
WP_058117506 261 TALSAsMDLIIKAAAVADYRPRSVAADKIKKS--AEarDLSLPLERTDDILGWLGEhRRp---GQLLCGFSMETRDLLEN 335
WP_068759322 260 EALKDdYDILVKSAAISDYRVERVSDHKMKKQ--GN--QLTIDFVTNPDILAHMGQlKKa---DQVVCGFAMETQDLVEN 332
WP_111525472 261 MKISDaQDIIIKAAAVADYTPANYCDEKIKKK--DG--DLTIELSRTKDILKELGErKEnnpkKQFICGFSMETENMEEN 336
WP_106790098 261 TSRSQkADLIIKAAAVADYRPREVSDEKVKKS--DQ--DLSIAMERTDDILGYLGEhKKd---GQFLCGFSMETEHLLEN 333
WP_013281450 261 KDSSDeQDIIIKAAAVADYTPETVADDKIKKSdnDS--DLSIKLKRTTDILAFLGEhKKd---GQVLCGFSMETRDMLEN 335
WP_013064628 261 TSRSAeADVVIMCSAVADYTPAVYADQKVKKH--DG--DLQIELKRTQDILGWLGEhKPa---KQTLVGFSMETENLIEN 333
WP_010235885 396 AQAKRARKKADWIIANDVSGGVGqsVMGGAHNTIHLVTEEGVEDWPQMPKEEVAMRLVERIALALEN 462
WP_065533694 334 SRRKLEKKHLDLIAANNLKEPGA--GFAVPTNLLTLISPREELELPLLTKEEAAHRLLDEILKLR-- 396
WP_012799435 331 SRGKLQRKNVDMIAANSLREPGA--GFGTPTNHLTFITAEGeIDLPLLSKGEAADRLLDELFKLTPK 395
WP_106057729 334 SRSKLERKCLDMICANSLRDAGA--GFGGDTNIVTIITKDDETELGKLSKFDTAMAIIDKAKVLSQK 398
WP_058117506 336 SRKKLAKKHLDLIAANNLREEGA--GFGTATNLLTLITAERETPLPLLSKDEAAHRLLDELLALRST 400
WP_068759322 333 ATKKLVNKGADLIVANQLNEDAA--GFKKDTNVVTMLTGEGVTKLDVMSKEALGYEIMNRLLQILVK 397
WP_111525472 337 SKSKLVKKNVDMIVANNVKIEGA--GFGTDTNVVTIFTKDDEIRLDKLSKLEVAEKIFDEIVRNF-- 399
WP_106790098 334 SRKKLEKKHLDMIIANNLKIPGA--GFETDTNVVTLITKDQETSLPIMSKEELAFVILDHILGTWYF 398
WP_013281450 336 SRKKLSKKNLDMVCANNVKVEGA--GFGVDTNVITLITKEGERQLELMSKFQAAQQILTGLLDIKNN 400
WP_013064628 334 SRAKLLKKHAQLICANSIAGGNT--GFAVDTNKVTLISSQEVKELPLCSKEETADLIIDHIQTLA-- 396
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