3BRS


Conserved Protein Domain Family
PBP1_ABC_sugar_binding-like

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cd20006: PBP1_ABC_sugar_binding-like 
monosaccharide ABC transporter substrate-binding protein such as CUT2
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 380661
Aligned: 26 rows
Threshold Bit Score: 314.536
Created: 14-Dec-2017
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand binding
Conserved site includes 11 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to other sugar-binding proteins

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           #     ##                           #                                      
3BRS_A     10 CIPKVLDds-sdFWSVLVEGAQMAAKeyEIKLEFMApe--kEEDYLVQNELIEEAIKr---KPDVILLAaadyektyDAA 83  Clostridium phytof...
AEI45491   41 EIALIVKsknsdYWKAVISGAEAAEKelGVDVLVEApe--sEQDIQGQIGLISDVINy---KRSALVLApsddmapaDAV 115 Paenibacillus muci...
EEG87838   47 KVVFLTKsmdssFWQSAYAGAGAASAeyNLDLVCEGpdgdgEEDYEAQNEMIDRAIRe---QVDALLFSaidfeknaEAI 123 Coprococcus comes ...
SET37428   29 KVAVIVKsttsqFFKSVFSGANAASKeyNLELAFDGpe--nEEDYASQIEMMEKAIKd---KVDAIVLSaidyrklvVSV 103 [Clostridium] cocl...
KJB85134   35 TIDLIVKmnqgdYWNTLKSGAEAAAKefNVKLQFLApn--hEDDIPGQIELVNQSIQn---RPDAIILAasdymglaQAT 109 Paenibacillus sp. ...
SEM47471   29 QVDLIVKstdsdFWGSVYDGAKAAGAkyNINLRFLGpd--eEKNYRNQVRIIEQSAAr---KPDAIILAaadysimtKPM 103 Hydrogenoanaerobac...
ADY11921   29 RIAVITMmqggeFWGSLKNGARSARSstGSVLEFLApv--nESDYEGQISAVQKAIDq---HFDAIVISpshyskleDVV 103 Sphaerochaeta glob...
SKA91265   37 NIVFISKmsygyHWATVKQGAIAASKefNVDIDFAApd--lEENVEEQIKLVNNVIDnndkTVNAIVLAasdydelvDVI 114 Caloramator sp. US...
SEM71414   38 NIMFIAKssqsnFWKTAFQGARAAGNeyNVNVVIQApe--tEEDYGKQNEMLQWAIDn---SVDAVVFSacdfdksvKAA 112 Hydrogenoanaerobac...
ADL53510   41 NISLILLnqsddYWKNVKLGAETAAKefDIKLNIVApe--dGGDITIQQNLINEAVAm---KVDALLLVpssfqelvEPV 115 Clostridium cellul...
Feature 1                  #                                                  ##  #           
3BRS_A     84 KEIKDaGIKLIVIDsgmkqdiadiTVATDNIQAGIRIGAVTKnlv--rksGKIGVISFVKNs-kTAMDREEGLKIGlsdd 160 Clostridium phytof...
AEI45491  116 ARAAAnNIPVITIDsrldspkplsYIGVNHYEAGEKAGRKLAell--gdqGRAAVVGFKPDg-qAAAERERGFLDEmarh 192 Paenibacillus muci...
EEG87838  124 DRAAKaGIRIVVVDspvnseavecYIGTDNYEAGCMAGEEVLgnp--aenLNIGIVNFDKSt-eNGQLREKGFRDTvlkd 200 Coprococcus comes ...
SET37428  104 ENAIEaGIEVVIIDsdvdskkihtRISTNNYEAGKMAGDTVLklg--snvYNVGIVNFDVNt-aNGQERERGLRSVlskd 180 [Clostridium] cocl...
KJB85134  110 DRIAYqNIPIISIDsevgsarvktYVGTNNYEAGQLAAKRMIeli--hesGQIAVMNFVEAa-kNANQREEGFQDYvarf 186 Paenibacillus sp. ...
SEM47471  104 ENAVDaGIPVIMLDsavdsdrwksFVSTDNTNAGAVLAAEVAkrvd-ksdAKIGVISFVKNs-sPSQERYSGFTNYitqn 181 Hydrogenoanaerobac...
ADY11921  104 SQARSaGIKVVLADtalrnqdgdfLITTDYRQIGKAMAEHAFthfgdddsIHALVLGSMPNt-tSMTNLVESLVQTfser 182 Sphaerochaeta glob...
SKA91265  115 EKVYDkNIPVIVIDsevntskissNIITDNFEAGKKMGNILVdic--gkkAKIAIMSFIKGs-rNAKQREDGLISIiaky 191 Caloramator sp. US...
SEM71414  113 ERVIDaGIPVISIDspinsskelmMIGTDNILAGVQAGEKLAelt--dykGKVGIINFEEGs-aNGMQRERGCLDAilky 189 Hydrogenoanaerobac...
ADL53510  116 EAAVNkGIIVMTVDskvntakiacCIATDNLSAGKSAGEKLVsla--rmnSVAAIVGFDKKtgsNEFDRYKGIKEVtkdy 193 Clostridium cellul...
Feature 1                                           #                          #              
3BRS_A    161 -snkiEAIYYCDSnyDKAYDGTVELLTkypdisVMVGLNqySATGAARAIKDMsle-akVKLVCIDSSmeqiqyLEEGIF 238 Clostridium phytof...
AEI45491  193 pkiqvVEKTYCYAdpDQCGEGVRRLAHvlntptGIAVLHgaSTRGVVEEIVKEgle-grVKVVTMDSTpedieyLQEGIV 271 Paenibacillus muci...
EEG87838  201 drvniTASINVKStiTDAREGTERMLLdnpqinVIVTFNewTTLGVGDAVEALgag-erTQVVAFDSNvksigmLEKGNV 279 Coprococcus comes ...
SET37428  181 ervlsLETINVQSdiPSSIQATKDILLkypdinVIVTFNewTTLGVGYAIEQLgye-dkVSVIGFDNNivsikmLETEVV 259 [Clostridium] cocl...
KJB85134  187 pnvrvVDIQYSQSnqRNAEEITRRWLAqypsldGIVALNaeSSIGVGREVQRSghg-grVKVVAFDSPpetmglLQDGVV 265 Paenibacillus sp. ...
SEM47471  182 trmsiASTVYCDSdiDLARKLTLEMIKnspditVIVGLNaqAATGAARALAELgr--kdVFLAAIDCTveqaayMEQDIL 259 Hydrogenoanaerobac...
ADY11921  183 pnakiVSATYSFTdeAIARDITVNALRndpsinLIFALEeyTAHGVANALGETs----sVHFIAFGTTqyeiqlLEKGVI 258 Sphaerochaeta glob...
SKA91265  192 pdiklISKEYCYSdtSLACNLTKKLLLenedidGIVALNdiSSEGVALAVDEMklg-gkVKVIAYDSTtqelhyLEKGVI 270 Caloramator sp. US...
SEM71414  190 pnmevVDIRYTLSniENPKLNTIDMLKenpeinAIATFNewTTLGVGEALKEMdidkdkIAVIGFDNNlksieqLERGIF 269 Hydrogenoanaerobac...
ADL53510  194 keiqvIDRWCDIKdsNGAERIAKELISnnedisVIIALNykASIGVARAIEKLglk-gkIKVVAFDGDyqevkyMEDGTI 272 Clostridium cellul...
Feature 1          #                                    
3BRS_A    239 EAMVVQKpFNIGYLGVEKALkllkk-eyvpKQLDSGCALITK 279 Clostridium phytofermentans ISDg
AEI45491  272 QATIIQNpFSMGYLGVQYAVdaleg-rrvkENFFTDTKVIDQ 312 Paenibacillus mucilaginosus KNP414
EEG87838  280 DALIVQNpYAMGYLGIEQINtllngqkpekKETATSSILVTR 321 Coprococcus comes ATCC 27758
SET37428  260 DALIVQNpFAIGYLGVEQAYylsrk-qggeERIYTKTVVINK 300 [Clostridium] cocleatum
KJB85134  266 QALVLQNpFNNGYLAVKYAVdiieg-rnvpERIDTGVKLIDL 306 Paenibacillus sp. E194
SEM47471  260 KVAVLQNpYLMGYFSVQTTYkvlkk-elveKNIATDVCVVDK 300 Hydrogenoanaerobacterium saccharovorans
ADY11921  259 DALVVVNsFNLGYRSVMAAIdlln--gtkpARKMIDFDLVTK 298 Sphaerochaeta globosa str. Buddy
SKA91265  271 QALVIENpFSIGYLGVKFAVdklng-kkipSKYLMETKVIDK 311 Caloramator sp. USBA A
SEM71414  270 DGLIVQNpFAMGYIGIQQAIeykkn-kqheDFIDTGTKVITA 310 Hydrogenoanaerobacterium saccharovorans
ADL53510  273 QSVVIQSpFSMGYLAVKNAVlklqg-ksipRYIESGFTVIDN 313 Clostridium cellulovorans 743B

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