Conserved Protein Domain Family
HMG-box_SoxC_SOX11
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cd22037: HMG-box_SoxC_SOX11 
high mobility group (HMG)-box found in sex determining region Y (SRY)-box 11 (SOX11) and similar proteins
SOX-11 is a neural transcriptional factor involved in precursor survival, neuronal fate determination, migration and morphogenesis. SOX-11 belongs to group C SRY-related high-mobility group (HMG) box (Sox) transcription factors.
Links
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Statistics
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PSSM-Id: 438846
Aligned: 7 rows
Threshold Bit Score: 168.733
Created: 8-Apr-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative DNA
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:based on the structure evidence that Mus musculus SOX-4 binds DNA
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                  # ## ## ##   #  #   #      ###  ##  #  ##                 #           
P35716        38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYK 117 human
Q66JF1        37 DPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLNDSEKIPFIREAERLRLKHMADYPDYK 116 tropical clawed...
P48435        38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYK 117 chicken
XP_007902941  42 DPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDGEKIPFIREAERLRLKHMADYPDYK 121 elephant shark
NP_571412     35 KPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLQHMADYPDYK 114 zebrafish
P40650        34 DPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLNDSEKIPFIREAERLRLKHMADYPDYK 113 African clawed ...
XP_005998976  38 DPDWCKTATGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDGEKIPFIREAERLRLKHMADYPDYK 117 coelacanth

Feature 1        # ###       
P35716       118 YRPRKKPKMDPS 129 human
Q66JF1       117 YRPRKKPKVDPS 128 tropical clawed frog
P48435       118 YRPRKKPKMDPS 129 chicken
XP_007902941 122 YRPRKKPKTESG 133 elephant shark
NP_571412    115 YRPKKKPKLDSS 126 zebrafish
P40650       114 YRPRKKPKVDPT 125 African clawed frog
XP_005998976 118 YRPRKKPKIDTS 129 coelacanth

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