Conserved Protein Domain Family
FAM163

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pfam15069: FAM163 
FAM163 family
This protein family is alternatively named Neuroblastoma-derived secretory proteins. Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.
Statistics
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PSSM-Id: 464484
Aligned: 26 rows
Threshold Bit Score: 202.613
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005938728   1 MSAGTVVIAGGILATVILLTIVAVLCLCRLQYYCCKREESEKgEEEEPELATmspSRPLalsapp--------------- 65 
XP_003353751   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEE-DEEEPDFAVhahVPPL--------------------- 58 
XP_006918160   1 MTAGTVVITGGILATVILLCIVAVLCYCRLQYYCCKRDQEDPeEDEEPDFAVhpsLPPL--------------------- 59 
XP_003229625   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEE-DGEEPDFDAdsrIPPL--------------------- 58 
XP_007253909   1 MTAGTVVISGGIIAAVILLTIVTVLCCCRLQYYCCRRDGSEG-EEEEPDLTK---ASPSppheassspqsthsppsllgf 76 
XP_005812522   1 MSAGTVVIAGGILATVILLTIVAVLCLCRLQYYCCKPEESEK-DDEEPELSTmspSRPLalcapp--------------- 64 
XP_014324479   1 MTAGTVVITGGILATVILLLIIAVLCYCRLQYYCCKKEESES-EEEEPDFAVtsrIPPV--------------------- 58 
XP_006640587   1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKEESEE-DEEEPDFAMhshLPPV--------------------- 58 
XP_005990667   1 MTAGTVVITGGILAAVILLCIIAILCYCRLQYYCCKKEDVDD-DEEEPDFAMhshIPPF--------------------- 58 
Q0VFM5         1 MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKEDSEE-DEEEPDFAVhsrFPPM--------------------- 58  tropical clawed...
XP_005938728  66 -tpptpeQYSDEPETypptflteANGPVSYSPPp-PPPRRCYRSHAFCPSCARCSLP-FYLQ---------HPER--LCN 131
XP_003353751  59 -------HSNRNLVL--------TNGPALYPAAstSFSQKSPQARTLCRSCSHYEPPtFFLQ---------EPEDegVRN 114
XP_006918160  60 -------HSGRSLVL--------TNGPALHPAAapAFGQKSPQARALCRSCSHHEPPaFFLQ---------EPEDggMRN 115
XP_003229625  59 -------HCNRNVAL--------TNGPSLYHSPs-P-FKKASQCRTVCPSCSHYEPPtFFLQ---------EPEEe-VRN 111
XP_007253909  77 hpppeysSSNQLLMTaep---yePNGPSTYNRYspALPRKPIRSYTFCPSCSGY-LP-FYLN---------PQEG--LRN 140
XP_005812522  65 -tpptpeHYSDELESypptflteANGPCSYSPPppAPPRRGQRVHAFCPSCARCSLP-FYLQ---------HPER--LCN 131
XP_014324479  59 -------HSNHNIVAataaassmPNGPAIFSTP--PLARKLTRSQTFCPSCTHYDLP-FYLQppppqqvhhQPEG--LRN 126
XP_006640587  59 -------HCNQNVVAata--aatANGPALFTPP--P-ARKLVRSRTYCPNCTHYELP-FYLQ---------HPDG--LRN 114
XP_005990667  59 -------HYNPNVAS--------TNGPSLYSP----FMKNHSHSRNFCPNCSSFEVP-IYLH---------PPED--VRN 107
Q0VFM5        59 -------HSNRNIVL--------ANGPSIYSSP---YNKKHQHCRSV---CTHHEPPaFLLH---------PPEE--IRN 106 tropical clawed...
XP_005938728 132 GGRRISYRTVQQQDMEL---PMDLASFyQKLNLIRQVTMKEVVTH--SVSTDV 179
XP_003353751 115 GGERVAYRSISQEDVELg-pPGSFGAL-QALNPNRLSAMREAFSRsrSISTDV 165
XP_006918160 116 GGQRVAYQSLGQDDLELp--PGTFAGL-QALNPNRLSAMREAFSRsrSISTDV 165
XP_003229625 112 GGDLVNYKAISQEDLEL---PVSANSL-QALNPNRLSAMREAFSRsrSISTDV 160
XP_007253909 141 GGGRISYKTLQQQELDLpvvPVDIPNY-NKLNLIRSVTMREVVTHh-SVSTDV 191
XP_005812522 132 GGRRISYRTVQQQDLEL---PADLDSFyQKL--IRSYTMKEVVNH--SVSTDV 177
XP_014324479 127 GGERVSYRSVQQQDLDLp-vPVNISNY-RKPNLARSVTMREMFTRscSISTDV 177
XP_006640587 115 GGERVSYRTVQQEDLDL---PLDLPSM-HKLNLARSVTMKEVFTRsrSISTDV 163
XP_005990667 108 GGDRIAYQAITQKDLEV---PISMANL-QNFNPSRLSAMRATFSRskSISTDV 156
Q0VFM5       107 GGERIAYKTISQEEIEL---PVNVSNL-QVLNPNRLSAMREAFSRsrSISTDV 155 tropical clawed frog
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