Conserved Protein Domain Family
PolyG_pol

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pfam01518: PolyG_pol 
Sigma NS protein
This viral protein has a poly(C)-dependent poly(G) polymerase activity.
Statistics
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PSSM-Id: 250679
Aligned: 4 rows
Threshold Bit Score: 540.222
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9DKH4   1 MDNTVRVGVSRNTSGAAGQTVFRNFYLLRCNISADGRNATKAVQSHFPFLSRAVRCLSPLAAHCADRTIRRDNVKQLLTR 80  Avian orthoreovirus s...
O72468   1 MERSMRVGVSRNAAGTGSQTILRGFALLRCVLSADSRQATRAVQSHFPGLGRMTKCLSPLTALSADRTVRHVSVATVLSR 80  Nelson Bay orthoreovirus
Q86308   1 MASSLRAAISKIKRDDAGQQVCPNYVMLRSSVTTKVVRNVVEYQIRTGGFFSCLVMLRPLQYAKRERLLGQRNLERISTR 80  Reovirus sp.
O72469   1 MSAGLRLNVSRAVAGRKDQTFLSRLHLLKVVKNEKN-------ELFFPNAKSVAKQLNPLFCVARDRILKKSPKVNFAEK 73  Baboon orthoreovirus
Q9DKH4  81 ELPFPSDL-ISYAHHVNSSSLT-TSQGIEAARLVAQVYGEQl-sFDHI----YPSGSATYCPGAIANAISRIMAGFVPrE 153 Avian orthoreovirus s...
O72468  81 DAKVLADY-ALTCHHPGDLPATlTPVGLEAARLVIAKFSERgmdLAHV----LPPDASSYSPIVMCHLIARVMSGFVPmR 155 Nelson Bay orthoreovirus
Q86308  81 DILQTRDL-HSLCMPTPDAPMS-NHQAATMRELICSYFK-----VDHAdglkYIPMDERYSPSSLARLFTMGMAGPHI-T 152 Reovirus sp.
O72469  74 LNKTVTDYiHQVIYDEGQFPTS-RVSADILKTLLSDCYGEG---FEHVantiIP--SDSYIPGALAKAFTMSLAGMAP-E 146 Baboon orthoreovirus
Q9DKH4 154 GDDFTPSGAIDYLAADLVAYKFVLPYMLDvvDGRPQI-VLPSHTVEEMLTN-TGLLNSIDASFGIESRSDQRMTRDAAEM 231 Avian orthoreovirus s...
O72468 156 GNDFGLEGRVDLLAAELVPFSFMLPFLVN--DDASAI-AVPTARVEDMLQD-ISKLNQLDAAFGVESRSDQRMTKDVAED 231 Nelson Bay orthoreovirus
Q86308 153 TEPSYKRVPIMHLAADLDCMTLALPYMITl-DGDTVVpVAPTLSAEKLLDDgLKGLACMDISYGCEVDANNRSAGDQSMD 231 Reovirus sp.
O72469 147 GDNKYIDTPVYHGAAELIVFQRGLPYTIApvKGGTTI-DRPINGVEYTLGQ-LANLDTIDISYGVDVRGDN-VTQDSINA 223 Baboon orthoreovirus
Q9DKH4 232 SSRSLNELEDHEQRGRM-PWKIMLAMLAAQLKVELDALADERTESQANAHVTSFGSRLFNQMSAFVPIDRELMELALLIK 310 Avian orthoreovirus s...
O72468 232 SSRSLNELPSSENRGRM-PWKLMLAFLTFQLKLELDALADQRSELQSQAHVTSFGSKLFQQMSLFSTLDSELLSLALAIK 310 Nelson Bay orthoreovirus
Q86308 232 SSRCINELYCEETAEAIcVLKTCLVLNCMQFKLEMDDLAHNAAELDKIQMMIPFSERIFRMASSFATIDAQCFRFCVMMK 311 Reovirus sp.
O72469 224 SSRSINELPEDRLIEKL-VLKVIVVLNALQLKRELD-IAHEHVKDD----IVGFGLQLLKQYSFLAGIDRDLCNLMISIA 297 Baboon orthoreovirus
Q9DKH4 311 EQGFAMNPGQVASKWSLIRRS-GPTRPLSGARLEIRNGNWMIREGDQTLLSVSPARM 366 Avian orthoreovirus strain 601G
O72468 311 DSGLVMNPIQILTKWQSIRTG-SDAVNPASFSVVVRAGNWVLMKGEDAALTVRPGRI 366 Nelson Bay orthoreovirus
Q86308 312 DKNLRIDMRETMRLWT--RSAlDDSVATSSLSISLDRGRWVAADANDARLLVFPIRV 366 Reovirus sp.
O72469 298 DNK-EASFNDVSRYWSEIRSG-SRDLDTIGMVAKFTNGALKICQGEDVKLTIRPTRI 352 Baboon orthoreovirus
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