6GAW


Conserved Protein Domain Family
MRP-S27

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pfam10037: MRP-S27 
Mitochondrial 28S ribosomal protein S27
Members of this family of small ribosomal proteins possess one of three conserved blocks of sequence found in proteins that stimulate the dissociation of guanine nucleotides from G-proteins, leaving open the possibility that MRP-S27 might be a functional partner of GTP-binding ribosomal proteins.
Statistics
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PSSM-Id: 462947
Aligned: 19 rows
Threshold Bit Score: 345.964
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6GAW_Ae       41 MASSIVRRGILRARKV--SLpQLSL--AGRRCLLSAAYVDSHKWEARDKED----CHLADLA--------SLMDKTYER- 103
XP_001504081   1 MAFPMERFSMFLARRR--LV-PAPAl-AGKRYLLSAAYVDSRKWEAREKEH----CHLADLA--------SLMDKTYER- 63 
PNI73393       1 MAASIVRRGMLLARQV---V-LPQLspAGKRYLLSSAYVDSHKWEAREKEH----YCLADLA--------SLMDKTFER- 63 
Q8BK72         1 MAAPMVRCGMLLARRL--DA-SRLCl-AGKRCLLSAAYVDSHQWEAREKEE----YHLADLA--------SLMDKAYER- 63  house mouse
XP_424803      1 MAASVLVRGALRGGKVvgAa-------AGRRSLLSAAYVDSSKWESRQKEE----HNLADLA--------NLMDRTYER- 60 
EEB18161       1 MIKNLCNKSYNLSKNNnfFV-RLFK-----RSFLSESYKCIDEWENRLKHPifkkSNVDNIY--------NQLKLDFDT- 65 
EFA02747       8 ATRRGFLKTINSQ--------RSYL-----RTFLSQAYYCNEVWDSRLNSPllqkVNLDGLY--------YELDQGFQK- 65 
EGT57455       1 MLSKHIIRALIPRRNIhkTV-RNPV--------LSQSFFLENEWSGRH-------VALGKLGlggdyewiSAVQKKFIG- 63 
XP_001959426   1 MLRSRISCALPT---------RRLM------SYLSPEF--------------------NKLA--------NEGPKISAA- 36 
O77477         1 MLRSRISCALPP---------RRLV------SYFSAEF--------------------NKVA--------HEGPAKFAAg 37  fruit fly
6GAW_Ae      104 -KLPVSSLTISRFVDNIASREDIDHAEYYLYK--------------FRHSPNCWYLRDWTIHTWIRQCLKYGAQDKALYT 168
XP_001504081  64 -KLPVSSLTISRFVDNISSREEVDHAEYYLYK--------------FRHSPNCWYLRDWTIHTWMRQCLKYGAQDKALYT 128
PNI73393      64 -KLPVSSLTISRLIDNISSREEIDHAEYYLYKkgecsssspqnysrFRHSPNCWYLRNWTIHTWIRQCLKYDAQDKALYT 142
Q8BK72        64 -KLPVSSLSISRFVDNIASREDLDSAEYYLYK--------------FRHSPNCWYLRDWTIHSWIRQCLKYGAQDKALYT 128 house mouse
XP_424803     61 -KLPVSSLTIGRFVDNISSREEVDQAEYYLYK--------------FRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYT 125
EEB18161      66 -NKRISVLDVDILANSFKDYNEKFEVEDTLKK--------------LRECPECVLLPERSTHAILRYYIDHGPKEDIFNL 130
EFA02747      66 -TRRISPVDVDIFANALKDDVFIDELLDLVHK--------------LRLSPDTGNTLNSTSHAVVRTLLRNDKVKELLQV 130
EGT57455      64 -GGYASAVDVDAAVCVAEQKDQVDDVIELLYK--------------LRHSVKAAEKLESSEYALVRLLLKY-QPETILTL 127
XP_001959426  37 -SHVAANMDLDLFVNP---DNRPMDLVDRLAK--------------LRSQKEASLVPLFPS-VLVKQLLDSTNPQEAISV 97 
O77477        38 sSHAVTSVDLDVFVNP---DNRPMDLVDRLLK--------------LRKQKEASLVPLIPS-VLVKQLLDSTNPQETISV 99  fruit fly
6GAW_Ae      169 LKNKVQYGIFPDNYTFNLLMDYFIKKENYKDALSVVFEIMMQEAFEVPSTQLLSLYVLYHCLAE---------------- 232
XP_001504081 129 LVNKVQYGIFPDNFTFNLLMDHFIKQENYKDALSVVFEIMRQEAFEAPSTQLLSLYVLYHCLAS---------------- 192
PNI73393     143 LVNKVQYGIFPDNFTFNLLMDSFIKKENYKDALSVVFEVMMQEAFEVPSTQLLSLYVLFHCLAK---------------- 206
Q8BK72       129 LVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPSTQFLSLYVLYRCLAE---------------- 192 house mouse
XP_424803    126 LKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVVYQYLAT---------------- 189
EEB18161     131 LSNRLEYGVFPDFYLINMLMDKFLKNEDYVSAVKIAVLQMLQEEYGHPITKSLAIFSCYKYLLSsmvwsvppppepdpde 210
EFA02747     131 LDDRLNYGVFLDDYTANILMDKFWKSKDFAAGCLVASQMMLQEDLKHPVTVNLALLHCYNYLLKpgdwlempqpeepee- 209
EGT57455     128 ANDPINYGVFLNPHLACIVIDHFIKTSNIQAAARIVTWMVQQEELDNELLNVLGLYVCAKWAELpadqqtlelggseeee 207
XP_001959426  98 LRSPTQYGLFVDQFSGCYLMDVLLHNGNAVEAAQVAAILVERGLCNNELVEALALQSFYGYAKDfkpvvaepqdkpapka 177
O77477       100 LRNPIQYGLFVDQFSGCFLLDFLLHNGHAVESAQLATILVDRNLCNNELLESLALQSFWSFAKEfkpfessqvqppakn- 178 fruit fly
6GAW_Ae      233 --------------------KTDLSWEEERNF-GASLLLP-GLKQK--NSVGLSSQLYGYALLGKVelqqglravycnmp 288
XP_001504081 193 --------------------KTDLSWEEERNF-GASLLLP-GLKQR--NAVGLSSQLYGYALLGKVelqhglravyhnmp 248
PNI73393     207 --------------------KTDFSWEEERNF-GASLLLP-GLKQK--NSVGFSSQLYGYALLGKVelqqglravyhnmp 262
Q8BK72       193 --------------------KTELTWEEERDF-GASLLLS-GLKQR--NTVGLSSQLYGYALLGKVelqrgvravyhgmp 248 house mouse
XP_424803    190 --------------------KSEHTWEEERNL-GASLVLT-GLKQT--STVGFSSQLYGYAFLGKVelnkglravynlmp 245
EEB18161     211 -----dvvkvrvpyirnpyfDDHFDITEPNHLvGKTMWLF-GKNIN--GPLGISSQLVGLILYEK--------------- 267
EFA02747     210 ------evkirvnyirnpfnDEHFDLREPQKIvGKTLA---AATRDrnDSLHNSLRIIGLALFGKE-------------- 266
EGT57455     208 dvndddirtfkfpylknecfDEHFDLTNPHHLiGKSLQWLsRDTQSidKDLKSSLNALGAVLFEK--------------- 272
XP_001959426 178 -----sdvekvrvkfirnyhEDPSEKTEEKKL-GRAMVKI-GSGEGslKDLKQNIALLGYVIAGQ--------------- 235
O77477       179 -----vevekvrvkfirnypDDASENTEEKKL-GRAMVRL-GSGEGslKELKQNVALLGYVLTGQ--------------- 236 fruit fly
6GAW_Ae      289 llwqpGYLHRALQVMEKVASSPEDGQLCGEALDVLDRVLKAVtapaqgtseeqpqegeesqrseelveqLDVEETEQSKL 368
XP_001504081 249 llwqpGYLDRALQVMEKVASCPEGEKLCGDALDVLDRVLKAVtapaptsseeqpregedgqrpaelveqMDVEERQQSRL 328
PNI73393     263 liwkpGYLDRALQVMEKVAASPEDIKLCREALDVLDAVLKALtsadgaseeqsqn-dednqgseklveqLDIEETEQSKL 341
Q8BK72       249 lmwtpGYLDRALQVMERVASSPEDLKLGREVLDVLDGVLKVVtspdvqtseaqpqegedglgsanlveqLDTEEPEQSKL 328 house mouse
XP_424803    246 lmwtpGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVleakpgpepse-----eakeveqkseyAESEKTEQSKI 320
EEB18161     268 -------FNETISLLNTIIEKDL--KLHSQAVSMAKDFLTNK---------------------------PKQDSSD---- 307
EFA02747     267 -----ELVKKEMEARKNT-------KLIKQVVQLL--------------------------------------------- 289
EGT57455     273 -------LQEAGSTVS---------TAHSSVKQLIAERLAPK----------------------------EREEQP---- 304
XP_001959426 236 -------LADASSFLEKNKQ-----SFHKDTLTAAQSAAEGS----------------------------KLEGAE---- 271
O77477       237 -------VPEASSFLASNSA-----ALHKETLLAAQSIVESL----------------------------KLEGSE---- 272 fruit fly
6GAW_Ae      369 PQYLERFEALRSKLQALGKVESESLLTLSTQLAKAQLPTCEAEDIAVYEQRLQQWHGERVRLIQREQEQRERARQDYEAR 448
XP_001504081 329 PQYLERFQAARSQLQALGRVESGSLLTLTTQLVHEELPTYEAEDMAAYEQQLQQWQQERARLVQREQEQRERAKQEHEAR 408
PNI73393     342 PQYLERFKALHSKLQALGKIESEGLLSLTTQLVKEKLSTCEAEDIATYEQNLQQWHLDLVQLIQREQQQREQAKQEYQAQ 421
Q8BK72       329 PRYLERFQASRSKLQELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQREQEQREKAKQEYQAL 408 house mouse
XP_424803    321 PEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEAR 400
EEB18161     308 -SIKNEILQLLTKINSKNLLKTD-LLTESENLLKHSIENNERNDIDNQCKIYSRWENDRNEHINKELERSEIENLKMEIA 385
EFA02747     290 -PDDNPFKADLTQLE----LVSEDVQTILEKQLTESIAVTSEKDIANQCSLFKQWENERLQALEEQKKRLHTLERLAEVE 364
EGT57455     305 -EEQKAILEKIGTVEKSNQLLSDIILEHLTRIQ----KAEEEKLCSQQTALFATWNERRQELAKSQAQKVLLRIRQDEIR 379
XP_001959426 272 -ELVKSLQDALEKTT-----KTNAIAEQLENSVKSSAQKYEPKLLADYGDSYQKWAVEFEKAVSKKTEERSLDLRRDNIN 345
O77477       273 -ELLKSLQEAVEKSS-----KSNAIQSLLENSVKANVQKFEPKLLADYGESYQEWAKKFEAAVQRQLDSQSVEERKATIQ 346 fruit fly
6GAW_Ae      449 RAAKA 453
XP_001504081 409 RAAQL 413
PNI73393     422 KAAKA 426
Q8BK72       409 SAAEK 413 house mouse
XP_424803    401 KLAKA 405
EEB18161     386 KVKEE 390
EFA02747     365 RMKKE 369
EGT57455     380 AELKQ 384
XP_001959426 346 KTLSE 350
O77477       347 KTLSE 351 fruit fly
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