Conserved Protein Domain Family
Smoothelin

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pfam12510: Smoothelin (this model, PSSM-Id:403640 is obsolete and has been replaced by 463614)
Smoothelin cytoskeleton protein
This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.
Statistics
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PSSM-Id: 403640
Aligned: 16 rows
Threshold Bit Score: 36.5541
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004063366         655 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 704  western lowland gorilla
XP_008182947        1531 QSISIQNADDEVEIEEIFDLHILETMLEKAVGYDRRRRIRAQIR-VVKRQ 1579 pea aphid
EDW00113            3189 LRTTSISEDFDIDIEAIFELATLEQLLETVSSYELRRRIRAQIRLIKKNM 3238 Drosophila grimshawi
FlyBase:CG34417-PQ  2591 DEDS----DLELEIEEIFDLQRLEKLLETVASYEMRRRIRAQMRLIRKNM 2636 fruit fly
Q16M45                11 SSSSNAPKPSIENLEQIWDEAVLKQLLESSTNYEERRKIRARLRQIMAEK 60   yellow fever mosquito
XP_021332369         383 KTEAQSEKLTSEKLRDIEDEEILDKMLDECKDFEERKMIRTAMRELRKKK 432  zebrafish
WGS:AADE:GA22746-PI    1 MELE-------CDLGAIQNEELLRKMWQQSEDSERKKQIRSHLYKLR-ES 42   Drosophila pseudoobscura pseudoobscura
PNI97960              46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQE 95   chimpanzee
XP_016157632          77 EEQQAALTALSEQLEAITSVEELTKLLRAAGEYEERKLIRAAIRKLRAEE 126  collared flycatcher
PNI97964              73 AEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE 122  chimpanzee
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