6QWL,5D98


Conserved Protein Domain Family
Flu_PA

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pfam00603: Flu_PA 
Influenza RNA-dependent RNA polymerase subunit PA
Statistics
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PSSM-Id: 395480
Aligned: 5 rows
Threshold Bit Score: 1041.06
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6QWL_E  21 M---AEFSEDPELQPAMLFNICVHLEVCYVISDMNFLDEEGKSYTALEGQGKEQnLRPQYEVIEGMPRTIAWMVQRSLAQ 97 
Q9QLI9  21 M---AEFSEDPELQPAVLFNICVHLEVCYVISDMNFLDEEGKTYTALEGQGKEQnLRPQYEVIEGMPRNIAWMVQRSLAQ 97  Influenza B virus (B/...
Q6I7C2  18 VriaKEAVEEYGDHERKIIQIGIHFQVCCMFCD-EYLSTNGSD---------------RFVLIEGRKRGTAVSLQNELCK 81  Influenza C virus (C/...
P03433  21 M---KEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNAL-LKHRFEIIEGRDRTMAWTVVNSICN 96  Influenza A virus (A/...
5D98_A  18 vriaKEAVEEYGDHERKIIQIGIHFQVCCMFCD-EYLSTNGSD---------------RFVLIEGRKRGTAVSLQNELCK 81 
6QWL_E  98 EHGIETPKYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKL-GNSMELMIFSYN-QDYSLSNESSLD-------EEGKG 168
Q9QLI9  98 EHGIETPRYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKL-GNSMELMIFSYN-QDYSLSDESSLD-------EEGKG 168 Influenza B virus (B/...
Q6I7C2  82 SYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKL-GNSCKIFVFSYDgR---------LDkncegpmEEQKL 151 Influenza C virus (C/...
P03433  97 TTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIkSEKTHIHIFSFTgEEMATKADYTLD-------EESRA 169 Influenza A virus (A/...
5D98_A  82 SYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKL-GNSCKIFVFSYDgRLDKNCEGPM---------EEQKL 151
6QWL_E 169 RVLSRLTELQAELSLKNLWQVLI----GEEDVEKGIDFKlgQTISRLRDISVPAGFSNFEGMRSYIDNIDPK-GAIERNL 243
Q9QLI9 169 RVLSRLTELQAELSLKNLWQVLI----GEEEIEKGIDFKlgQTISKLRNISVPAGFSNFEGMRSYIDNIDPK-GAIERNL 243 Influenza B virus (B/...
Q6I7C2 152 RIFSFLATAADFLRKENMFNEIFlp-dNEETI---IEMKkgKTFLKLRDESVPLPFQTYEQMKDYCEKFKGNpRELASKV 227 Influenza C virus (C/...
P03433 170 RIKTRLFTIRQEMASRGLWDSFRqserGEETIEERFEIT--GTMRKLADQSLPPNFSSLENFRAYVDGFEPN-GYIEGKL 246 Influenza A virus (A/...
5D98_A 152 RIFSFLATAADFLRKENMFNEIFlp-dNEETI---IEMKkgKTFLELRDESVPLPFQTYEQMKDYCEKFKGNpRELASKV 227
6QWL_E 244 ARMSPLVSATPKKLKWEDLRPIgphiynhELPEVP---YNAFLLMSDELGLAnMTEGKSKKPKTLAKECLEKYSTLRDQT 320
Q9QLI9 244 ARMSPLVSVTPKKLKWEDLRPIgphiynhELPEVP---YNAFLLMSDELGLAnMTEGKSKKPKTLAKECLERYSTLRDQT 320 Influenza B virus (B/...
Q6I7C2 228 SQMQSNIKLPIKHYEQNKFRQI-------RLPKGPmapYTHKFLMEEAWMFTkISDPERSRAGEILID-------FFKKG 293 Influenza C virus (C/...
P03433 247 SQMSKEVNARIEPFLKTTPRPL-------RLPNGPpcsQRSKFLLMDALKLS-IEDPSHEGEGIPLYDAIKCMRTFFGWK 318 Influenza A virus (A/...
5D98_A 228 SQMQSNIKLPIKHYEQNKFRQI-------RLPKGPmapYTHKFLMEEAWMFTkISDPERSRAGEILID-------FFKKG 293
6QWL_E 321 DPILIMKSEKA-NENFLWKl---WRDCVNTISNEE------MSNELQKTNYAKWATGDGLTYQKIMkevaIDD----ETM 386
Q9QLI9 321 DPILIMKSEKA-NENFLWRl---WRDCVNTISNEE------TGNELQKTNYAKWATGDGLTYQKIMkevaIDD----ETM 386 Influenza B virus (B/...
Q6I7C2 294 NLSAIRPKDKPlQGKYPIHyknlWNQIKAAIAD--------RTMVINENDHSEFLGGIGRASKKIPevslTQDvittEGL 365 Influenza C virus (C/...
P03433 319 EPNVVKPHEKGiNPNYLLS----WKQVLAELQDIEneekipKTKNMKKTSQLKWALGENMAPEKVD----FDDckdvGDL 390 Influenza A virus (A/...
5D98_A 294 NLSAIRPKDKPlQGKYPIHyknlWNQIKAAIAD--------RTMVINENDHSEFLGGIGRASKKIPeislTQDvittEGL 365
6QWL_E 387 CQEEPKIPNKCRVAAWVQTEMNLL---STLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLFHT 463
Q9QLI9 387 YQEEPKIPNKCRVAAWVQAEMNLL---STLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLFHT 463 Influenza B virus (B/...
Q6I7C2 366 KQSENKLPEPRSFPKWFNAEWMWAikdSDLTG--WVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVG 443 Influenza C virus (C/...
P03433 391 KQYDSDEPELRSLASWIQNEFNKA---CELTDSSWIELDEIGEDVAPIEHIASMRRNYFTSEVSHCRATEYIMKGVYINT 467 Influenza A virus (A/...
5D98_A 366 KQSENKLPEPRSFPRWFNAEWMWAikdSDLTG--WVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVG 443
6QWL_E 464 SLLNESNASMGKYKVIPITNRVVNEKG--------ESFDMLYGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPK 535
Q9QLI9 464 SLLNESNASMGKYKVIPITNRVVNEKG--------ESFDMLYGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPK 535 Influenza B virus (B/...
Q6I7C2 444 ALMTECRLFPGKIKVVPIYARSKERKSmqeglpvpSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQ--K 521 Influenza C virus (C/...
P03433 468 ALLNASCAAMDDFQLIPMISKCRTKEG--------RRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEK 539 Influenza A virus (A/...
5D98_A 444 ALMTECRLFPGKIKVVPIYARSKERKSmqeglpvpSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQ--K 521
6QWL_E 536 YTVFRIGSLFVS--------GR-EKSVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKg 606
Q9QLI9 536 YTVFKIGSLFVS--------GR-EKPVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVDQESSIQGYDMTKACFKg 606 Influenza B virus (B/...
Q6I7C2 522 YTVFEAGHTTVRmkkgesviGR-EVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTL-- 598 Influenza C virus (C/...
P03433 540 YCVLEIGDMLIRsa-----iGQvSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFE- 613 Influenza A virus (A/...
5D98_A 522 YTVFEAGHTTVRmkkgesviGR-EVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTL-- 598
6QWL_E 607 drvNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYSGI 686
Q9QLI9 607 drvNNPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYFGV 686 Influenza B virus (B/...
Q6I7C2 599 ---NEKQMW-IGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKI 674 Influenza C virus (C/...
P03433 614 ---NKSETWPIGESPKGVEESSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAI 690 Influenza A virus (A/...
5D98_A 599 ---NEKQMW-IGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKI 674
6QWL_E 687 EECISNNPWVIQSAYWFNEW-LGFEK 711
Q9QLI9 687 EECISNNPWVIQSAYWFNEW-LGIEK 711 Influenza B virus (B/Lee/1940)
Q6I7C2 675 EECLINNPMCLFMAQRLNELvIEASK 700 Influenza C virus (C/Ann Arbor/1/50)
P03433 691 EECLINDPWVLLNASWFNSF-LTHAL 715 Influenza A virus (A/Puerto Rico/8/1934(H1N1))
5D98_A 675 EECLINNPMCLFMAQRLNELvIEASK 700
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