15899195 24 EMS-EIRE----LKKPIREKASIHSHIKGLGLDSNGKAKFIADGLVGQAEAREAAGVVVQLIKQGKMSGKGILFVGPPGT 98 Sulfolobus solfatar... 11499401 1 -MAgEIRE----ITQTFER-ISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGKMAGRGILMAGPPGT 74 Archaeoglobus fulgidus 14600633 24 GVSgEIRA----EVVRG-FGASRHSHITGLGLDADGRARKIGGGLVGQEEAREAAGVIVEMVREGRLGGRGILIVGPPGT 98 Aeropyrum pernix 19173260 1 --MvKSS------------NIAIHSHVRSLGLDDCGNPVEKPDAVIGQENAREAAGLIVEMVRTKRMSGRAVLISGPVGS 66 Encephalitozoon cun... 19074927 1 --MeIR-------DVETVNRINLHSHIAGLGCDGD-EVEYDKDGLVGQIKARKAMAVIRKMVESN-KGGKVVLIKGDRGS 69 Encephalitozoon cun... 20093447 1 MVEiKEIG----EVSTEETSPGAHSHITGLGLDENLKAKPVGDGLVGQEEAREAAGIVVEMVKQGRRAGHGLLLVGPPGT 76 Methanopyrus kandle... 14520579 1 MAViEELP----TIKFER--VGAHSHIRGLGLDENGKAKFIGDGMVGQIKAREAAGIAVKLIKQGKLAGKGILLVGPTGS 74 Pyrococcus abyssi 18312811 1 -MSiKIEE----VKTQF-ERFAAHSHIKGLGVR-DGKVEFIGDGFVGQVEAREAAYIVVKMIKEGKFAGKGVLIVGPPGT 73 Pyrobaculum aerophilum 14591557 1 MAViEELP----AIKFER--VGAHSHIKGLGLDENGKAKFIGDGMVGQVKAREAAGIAVKLIKQGKLAGKGILLVGPTGS 74 Pyrococcus horikoshii 19115695 4 ISEvKGN--------GRDNRITTHSHIKGLGLKEDGTCESVGGGFIGQEKAREACGIITDLIKSKKFGGKGVLFAGGAGT 75 fission yeast 19112432 4 SVTsHN-------DVSKLERIGAHSHIKGIGLNDNLEPKESSQGMVGQVKARRAAGVILKMIQEGRIAGRAILMAGPPST 76 fission yeast 6320396 4 ISEvKENPgvnsSNSGAVTRTAAHTHIKGLGLDESGVAKRVEGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPST 83 baker's yeast 6325021 4 QTSdPNET----SDLKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPST 79 baker's yeast
15899195 99 GKTALAVAIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSIGVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAP 178 Sulfolobus solfatar... 11499401 75 GKTAIAVAISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAIGVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIP 154 Archaeoglobus fulgidus 14600633 99 GKTALAIAIARELGEDTPFVALNAGELFRGDSGKLEMLLQAFRKAIGVRVRERREVVEGVVTSISVSKRRTPFSPY-PVI 177 Aeropyrum pernix 19173260 67 GKTALAVGISEELGAGTPFTSMSGSEVYSNEVKKTEVLEEALRRSILVRMRELKDVYEGEVVELRIVDEENPLSSYPKRI 146 Encephalitozoon cun... 19074927 70 GKTALAIGLSKSLG-GVHFNSISGTEIYSLEMSKSEAITQALRKSVGLRIKESVKVIEGEVVSLSGRR------------ 136 Encephalitozoon cun... 20093447 77 GKTAIAYGIARELGEDVPFVSISGSEIYGTNLSKTEFLQQAIRRAIGVEFTETREVIEGKVESLEIERAKHPLSPYMEVP 156 Methanopyrus kandle... 14520579 75 GKTAIAMGIARELGEDVPFVQISGSEIYSAEVKKTEFLKQALRRAIGVRISEERKVYEGMVEKMEVRRTRHPFNPYIEVP 154 Pyrococcus abyssi 18312811 74 GKTALALGIARELGSETPFVALSGGEIYSLEVKKSEFLMRALRRAIGIKVREWRKVYEGEVRSIELRYGKHPYNPYLQRV 153 Pyrobaculum aerophilum 14591557 75 GKTAIAMGIARELGEDVPFVQISGSEIYSAEVKKTEFLKQALRRAIGVRISEERKVYEGMVEKMEIRKTRHPFNPYIEIP 154 Pyrococcus horikoshii 19115695 76 GKTALALAIAQELGPKVPFCPMVGSEVYSSEIKKTEALMENFRRAIGLRVKETKEVYEGEVTEMVPEEAENPLGGYGKTI 155 fission yeast 19112432 77 GKTAIAMGMAQSLGSDTPFVTLSASEVYSLEMSKTEALLQALRKSIGVRIKEETEIIEGEVVEVQIDRSITGGNKQ---- 152 fission yeast 6320396 84 GKTALALAISQELGPKVPFCPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYGKTI 163 baker's yeast 6325021 80 GKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQ---- 155 baker's yeast
15899195 179 VEAQITLTTKDDERTLSVGEEIAQQLVSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGaKTYDIETTKVLEMPTGPVRKEK 258 Sulfolobus solfatar... 11499401 155 ESATLTLATKDEKRTFSVGGRLAMQFFTQGIEVGDVIVIDKETGRIGKLGRSEKAK--KKYDLGDDEVVPVPSGKVEKEK 232 Archaeoglobus fulgidus 14600633 178 AGARITLETKDESRTFTVGPEVAEQLVALGVRRGDVIVIDLETGVVRVVGRGKGRG--QSFDIDVVREVELPEGPVRKVK 255 Aeropyrum pernix 19173260 147 KEMFVILKTSKESKKLKLAPSLYEQIDKQRIVNGDVVYIEVNSGVIKKLGRSEAHMN--DFDLEADTYVPIPKGEVLKRK 224 Encephalitozoon cun... 19074927 137 ----IVLKTVDMESSFEIGEKMRGELDKEKVSAGDVIRIVRERGRVYKIGTSMVKRS--DVVGTDTRFVPCPEGELIRIT 210 Encephalitozoon cun... 20093447 157 SGAIIELKTQDDHRRFKVPEEIAIQLVQAGVREGDVIQIDVESGHVTKLGRAKDALEeEEEELLGVHAVELPEGPVQKKK 236 Methanopyrus kandle... 14520579 155 ESVIITLKTKDDKKTIRAGREIAYQLLELGIEEGDVIQIDAETGRVSRIGTTK-----EEEGLFFRKKVELPSGPVLKIK 229 Pyrococcus abyssi 18312811 154 MGATIKLRTRDEEKVLRIPAEIAQQIIELGVEEGDIIMIDEETGAVSVLGRGEGGE---QYDVAIKRRAELPKGPVYKEK 230 Pyrobaculum aerophilum 14591557 155 ESIRITLKTKDDKKTIRAGREIAYQLLDMGVEEGDVIQIDAETGRVSKIGTTK-----EEEGLFFKKKVELPTGPVLKIK 229 Pyrococcus horikoshii 19115695 156 SHVLLGLKTHKGTKQLKLDPSIYESLQREQVSTGDVIYIEANTGAVKRVGRSDAYAT--EFDLEAEEYVPMPKGEVHKRK 233 fission yeast 19112432 153 --GKLTIRSTDMETVYDLGTKMIDSLTKEKVLAGDVISIDKSVGRVTKLGRSFSRARdYDAMGADTRFVQCPQGEIQKRK 230 fission yeast 6320396 164 SHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAYAT--EFDLETEEYVPLPKGEVHKKK 241 baker's yeast 6325021 156 --GKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRdYDAMGADTRFVQCPEGELQKRK 233 baker's yeast
15899195 259 EITTTLTLNDLDLNLAARN----LAVTAIFSFFTer-eINEDVRKEVDRLVKDWINQGRAELVVGVLFIDDAHTLDLEAF 333 Sulfolobus solfatar... 11499401 233 EFTYVVTLHDLDEANARRTs---IFSLFSPPSRE----IDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLMDIELF 305 Archaeoglobus fulgidus 14600633 256 EFVRTLTLHDIDASIAAQR----VAFTGLLSMFEaergVTSEDRKKTDELVKKWVGEGKAEIVAGVIFIDDAHLLDMESF 331 Aeropyrum pernix 19173260 225 EVMQSVTLHDLDMANARPSgq-dMLSLVFRILSPrkteITERLRGDVNRMVNGYLENGNAEIVPGVLFIDEVHMLDVECF 303 Encephalitozoon cun... 19074927 211 EETQEISLHDIDVVNSKAEg---YLALFSGETGE----IRAETRDEVNKKVWGWINEGKAEIVRGVLFIDEVHMLDIESF 283 Encephalitozoon cun... 20093447 237 EIKRVVTLHDLDMANVRAG------RLLGFREEE----ITDEIRQKVDERVQKMVDEGEASLVPGVLFIDEAHMLDIEAF 306 Methanopyrus kandle... 14520579 230 EFTYTVTLHDLDVVNARAGg---IFSLIFGGGME----INDEIRERVDQTVKQWIEEGKATLVPGVLFIDECHMLDIEAF 302 Pyrococcus abyssi 18312811 231 EIVRFFTLHDIDVSLARQRg---LISAMIFGFAEevkeIPDEVRRQSDEIVKKTVEEGKAELVPGVLFIDDAHLLDIESF 307 Pyrobaculum aerophilum 14591557 230 EFTYTVTLHDLDVVNARAGg---IFSLIFGGGME----INDEIRERVDQTVKQWIEEGKATLVPGVLFIDECHMLDIEAF 302 Pyrococcus horikoshii 19115695 234 EIVQDVTLHDLDIANARPQggqdIMSMMGQLMKPkkteITDKLRGEINKVVNKYIEQGIAELIPGVLFIDEVHMLDIECF 313 fission yeast 19112432 231 EVVHTVSLHDIDVINSRTQg---FLALFSGDTGE----IKPEVREQINTKVSEWREEGKAEIVPGVLFVDEVHMLDIECF 303 fission yeast 6320396 242 EIVQDVTLHDLDVANARPQggqdVISMMGQLLKPkkteITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIF 321 baker's yeast 6325021 234 TVVHTVSLHEIDVINSRTQg---FLALFTGDTGE----IRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECF 306 baker's yeast
15899195 334 SFLTRALESELAPILILATNRGLTKIRGTD-IESPHGIPLDLLDRLLIIPTRPYNADEIKEIIKIRADELEIELDPQALE 412 Sulfolobus solfatar... 11499401 306 AFMNRAMESEMAPIIILASNRGFSRIRGTD-IVAPHGIPLDLLDRLLIITTEPYSREEIKTIIEIRAAESGIMLSNEAME 384 Archaeoglobus fulgidus 14600633 332 SFLSKAMESDLAPIIVLATNRGVAKIRGTD-IESPHGIPRDLLDRLLIITTRPYTRDEIKEIIRIRADEEEVLLSENALE 410 Aeropyrum pernix 19173260 304 TFLHKVIESPLSPTIIFASNKGMAPIKGSDgLLGPFGITKDLLDRIVIISVKRNPDEANREIIRRRMKEEGLEMDDDAFG 383 Encephalitozoon cun... 19074927 284 AFLNKAVEEDFCPVILVSTNKGECIVRGTD-EPSPYGIPRDFIDRALIISMEKHCRRDLEAILRHRILEEDILIDDDAVD 362 Encephalitozoon cun... 20093447 307 AFLNRSLEEEIAPILVMATNRAMAKVRGTD-EEAPHGIPGDLLDRMLIARTRPFERHEIHEIIGIRARVQDIQLTDEAHE 385 Methanopyrus kandle... 14520579 303 SFLARAMENELAPILILATNRGMTKIRGTD-LEAPHGIPLDMLDRLLIINTEPYKKEEIREIIKIRAKEEKIELSEEALE 381 Pyrococcus abyssi 18312811 308 SFLMRAMETEFAPIIIMATNRGIAKIRGTD-VEAPHGIPQDMLDRLVIIKTRPYTAEEIREIITIKAKEQNISLSKDALE 386 Pyrobaculum aerophilum 14591557 303 SFLARAMENELAPILILATNRGMTKIRGTD-IEAPHGIPVDMLDRLLIINTEPYKKDEIREIIKIRAKEEKVELSEEALE 381 Pyrococcus horikoshii 19115695 314 TYLNQALESTISPIVIFASNRGICTIRGTEdIQAPHGIPTDLLDRLLIVRTLPYSESEIRSILQIRAKVENIILTDECLD 393 fission yeast 19112432 304 SFFNRALEDDLAPIVIMASNRGITRIRGTN-YRSPHGIPVDLLDRMLIISTLPYSHEEVKEILKIRCQEEDVDMEPSALD 382 fission yeast 6320396 322 TYLNKALESNIAPVVVLASNRGMTTVRGTEdVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRATVERLQVESSALD 401 baker's yeast 6325021 307 SFINRALEDEFAPIVMMATNRGVSKTRGTN-YKSPHGLPLDLLDRSIIITTKSYNEQEIKTILSIRAQEEEVELSSDALD 385 baker's yeast
15899195 413 ELTKIGVENSLRYSVQLLEPSLIIAQRNNRSIIKVEDVVIASKLFSDVKRSVKFVKEYENLLL 475 Sulfolobus solfataricus 11499401 385 KLTDIGEKTSLRYAVQLLAPAYEFAKMRNSGKVELEDVERAASIFADVSQSSAYLKKWEEKML 447 Archaeoglobus fulgidus 14600633 411 RLADIGSEKSLRYAIQLLEPAMIVAKRRGSRRVEAEHVEEAERLFADIKRSIQLVEKYRDLMM 473 Aeropyrum pernix 19173260 384 FFVGLSTSRSLRYCISLIP----LLKTYGG-CVSVRNVEEVAELFHDS--------------- 426 Encephalitozoon cuniculi 19074927 363 RLVSISEASGLRYSMNLLTISSMRASRR-NGRVALGDVERAFELFLDEARGTESFNG------ 418 Encephalitozoon cuniculi 20093447 386 YLTDLGEEKSIRYATRLLEPARIVAEKEGSEVVEKKHVERVEEVFTDVSDSVEYMERMRRELP 448 Methanopyrus kandleri AV19 14520579 382 YLAELGEKTSLRYAVQLLAPASIIA---GGKRVEREHVEKAKEYFADVKRSIAFVEKLEGMLK 441 Pyrococcus abyssi 18312811 387 LLTKIGVEHSLRYALQLLTPAYIIAKERGKASVTKDEVEYVKSHFISVKESVEYVKSLEEKFL 449 Pyrobaculum aerophilum 14591557 382 YLADLGEKTSLRYAVQLLAPASIIA---GGKRVEKEHVEKAREYFADIKRSISFVEKLEGMLK 441 Pyrococcus horikoshii 19115695 394 KLAQEGSRTSLRYVIQLLTPVSIIASLHGNKEIGVQDIEECNDLFLDARRSAQVVKSSSGFLQ 456 fission yeast 19112432 383 YLSTIGQETSLRYALLLISSSNQVALKRKSATIEESDIRRVYELFLDQKRSVEYLEEYGKNYI 445 fission yeast 6320396 402 LLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAKRSTKILETSANYL- 463 baker's yeast 6325021 386 LLTKTGVETSLRYSSNLISVAQQIAMKRKNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYI 448 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",