6LS9,1L2G


Conserved Protein Domain Family
Herpes_glycop_D

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pfam01537: Herpes_glycop_D 
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Herpesvirus glycoprotein D/GG/GX domain
This domain is found in several Herpes viruses glycoproteins. This is a family includes glycoprotein-D (gD or gIV) which is common to herpes simplex virus types 1 and 2, as well as equine herpes, bovine herpes and Marek's disease virus. Glycoprotein-D has been found on the viral envelope and the plasma membrane of infected cells. and gD immunization can produce an immune response to bovine herpes virus (BHV-1). This response is stronger than that of the other major glycoproteins gB (gI) and gC (gIII) in BHV-1. Glycoprotein G (gG)is one of the seven external glycoproteins of HSV1 and HSV2. This family also contains the glycoprotein GX, (gX), initially identified in Pseudorabies virus.
Statistics
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PSSM-Id: 426313
Aligned: 22 rows
Threshold Bit Score: 102.02
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6LS9_C    52 VRYATSA-AACDMLALIADPQVGRTLWEAVrrh--araYNATVIWYKIESGCarPLYYMEYTECEPRKHFG--YCRYRTP 126 Bovine alphaherpesv...
P07645    56 VYHTRPLeDPCGVVALISDPQVDRLLNEAVahr--rptYRAHVAWYRIADGCahLLYFIEYADCDPRQVFG--RCRRRTT 131 Suid herpesvirus 1 ...
1L2G_A    59 VYYAVLE-RACRSVLLNAPSEAPQIVRGASedvr-kqpYNLTIAWFRMGGNCaiPITVMEYTECSYNKSLG--ACPIRTQ 134 Herpes simplex viru...
P36342    81 VYYAVLE-RACRSVLLWAPTEAVQVVRGAPeatrsdarYNLTVAWYRTSDDCaiPILVMEYAECQYDKPLG--ACPVRNL 157 Macacine alphaherpe...
Q67648    79 TKHVIYT-DNCSFAVLNPFGDPKYTLLSLLlmg--rrkYDALVAWFVLGRACgrPIYLREYANCSTNEPFG--TCKLKSL 153 Gallid alphaherpesv...
Q77L58    64 TKHVIYD-ENCGFAVLNPISDPKYVLLSQLlmg--rrkYDATVAWFVLGKMCarLIYLREFYNCSTNEPFG--TCSMSSP 138 Turkey herpesvirus
Q6X201    66 ARATDTS-HGCALVVLDMENSIVPSGPRDA--------AVIDAGWVYQNGDCmiPLAYRQFFNCTGNALPGedVCAGVSE 136 Bovine alphaherpesv...
ALJ84626  69 VRYVTSM-DSCGMVALISEPDIDATIRTIQlsq--kktYNATISWFKVTQGCeyPMFLMDMRLCDPKREFG--ICALRSP 143
Q6DLD9   129 LRIVTAT-RPCEMIALIAKTNIDSILKELAaaq---ktYSARLTWFKIMPTCatPIHDVSYMKCNPKLSFA--MCDERSD 202 Equine herpesvirus ...
O41524    49 VRYVTST-DPCDMVALISNPNIESTIKTIQfvqk-kkfYNASLSWFKVGDDCtyPIYLIQYFDCDPQREFG--ICLKRSP 124 Canid alphaherpesvi...
6LS9_C   127 PFWDS--FLAGFAYPTDDelglIMAAPARLVEGQYRRALYID-GTVAYTDFMV 176 Bovine alphaherpesvirus 1
P07645   132 PMWWT--PSADYMFPTEDelglLMVAPGRFNEGQYRRLVSVD-GVNILTDFMV 181 Suid herpesvirus 1 (strain Rice)
1L2G_A   135 PRWN---YYDSFSAVSEDnlgfLMHAPAFETAGTYLRLVKIN-DWTEITQFIL 183 Herpes simplex virus type 1
P36342   158 PRWS---FYDSFSATGDDdlglLMHAPAFETAGTYVRLVKVN-GWVEVTQFIF 206 Macacine alphaherpesvirus 1
Q67648   154 GWWDR--RYAMTSYIDRDelklIIAAPSRELSGLYTRLIIIN-GEPISSDILL 203 Gallid alphaherpesvirus 2
Q77L58   139 GWWDR--RYVSTSFISRDelqlVFAAPSRELDGLYTRVVVVN-GDFTTADIMF 188 Turkey herpesvirus
Q6X201   137 ARVRSgfGTSDYALSGTS----LVLRPGLYDSGTYVYFLGYGpNDIYAGSVTL 185 Bovine alphaherpesvirus 5
ALJ84626 144 SYWLE--PLTKYMFLTDDelglIMMAPAQFNQGQYRRVITID-GSMFYTDFMV 193
Q6DLD9   203 ILWQA--SLITMAAETDDelglVLAAPAHSASGLYRRVIEID-GRRIYTDFSV 252 Equine herpesvirus type 1 (strain AB4P)
O41524   125 DFWKP--SLVGYTFLTDDelglVLAAPAPFNQGQYRRVIQIE-NEVFYTDFMV 174 Canid alphaherpesvirus 1
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