Conserved Protein Domain Family
Adeno_VII

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pfam03228: Adeno_VII 
Adenoviral core protein VII
The function of this protein is unknown. It has a conserved amino terminus of 50 residues followed by a positively charged tail, suggesting it may interact with nucleic acid. The major core protein of the adenovirus, protein VII, was found to be associated with viral DNA throughout infection. The precursor to protein VII were shown to be in vivo and in vitro acceptors of ADP-ribose. The ADP-ribosylated core proteins were assembled into mature virus particles. ADP-ribosylation of adenovirus core proteins may have a role in virus decapsidation.
Statistics
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PSSM-Id: 281252
Aligned: 2 rows
Threshold Bit Score: 129.418
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P68950   1 MSILISPSNNTGWGLRfPSKMFGGAKKRSDQHPVRVRGHYRAPWGAhkrgRTGRTTVDdaidavveearnytptpppvst 80  Human adenovirus 2
Q83902   1 MSILVSPSDNTGWGIG-TSSMRATGLKFSKKQPVRVRPYYRAQWGQ----LNARTSLE---------------------- 53  Ovine adenovirus 7
P68950  81 vdaAIQTVVrgaRRYAKMKR---RRRRVARRHRRRPGTAAQRAA-----------------A 122 Human adenovirus 2
Q83902  54 ---KLKTKL---KYYEKLYRdrlKRKTVVPKKKRSPTSPADRLKkylkavsqikafnrarrA 109 Ovine adenovirus 7
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