Conserved Protein Domain Family
Adeno_E3_CR1
?
pfam02440: Adeno_E3_CR1 
Adenovirus E3 region protein CR1
Early region 3 (E3) of human adenoviruses (Ads) codes for proteins that appear to control viral interactions with the host. This region called CR1 (conserved region 1) is found three times in Adenovirus type 19 (a subgroup D virus) 49 Kd protein in the E3 region. CR1 is also found in the 20.1 Kd protein of subgroup B adenoviruses. The function of this 80 amino acid region is unknown. This region is probably a divergent immunoglobulin domain (A. Bateman pers. observation).
Links
?
Statistics
?
PSSM-Id: 367088
Aligned: 20 rows
Threshold Bit Score: 99.3578
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q6QPD0    15 ALCESVDRDVTITTGSNYTLKGP-PSGMLSWYcYFGTDTDQTELCNFQKGKtsnskisnYQCNGTDLILLNVTKAYGGSY 93  Simian adenovirus 23
ADP21162  13 AAVTYGRSHLTVPVGSTCTLQGP-QEGHVTWW-RIYDNGGFARPCDQPGTK--------FSCNGRDLTIINITLNEQGFY 82 
P15139    14 ATLTSARSHLTVTIGSNCTLKGP-QGGHVFWW-RIYDNGWFTKPCDQPGR---------FFCNGRDLTIINVTANDKGFY 82  Human adenovirus 35
Q4KSJ0   254 PTNTPETKQLTVSIGSNLTLVGP--DGKVTWY-----DGDLKRPCEEQNYRl------pHQCSAQNLTLINVTKSHEGTY 320 Human adenovirus 46
Q91CB8   236 STNNLQPTQLYVRPFTNVSLTGP-PNGKVIWY-----DGELNDPCEQKYKLr-------TFCNQQNLTLINVTSTYDGIY 302 Human adenovirus D8
Q80IV8   252 PH-TPEAKLITVSSGSDLTLLGP--DGKVTWY-----DDDLKRPCEPGYKLg-------CKCDNQNLTLINVTKLYEGVY 316 Human adenovirus 8E
BAH19045 260 PA-TIEAMLVTVTAGSNLTLVGPkAEGKVTWF-----DGDLKRPCEPNYRLr-------HECNNQNLTLINVTKDYEGTY 326
Q6H1B4    16 FINSFDHKNVTAYVGSNCVLTGYqSHQRVSWY-WFDKKNTAYTLCKGNQRPtqrs-glyYSCTNNNITLLQVTKQYSGTY 93  Human mastadenovirus E
Q6QPD1    15 YASGYANIQKTLYVGSDGTLEGTqSQAKVAWY-FYRTNTDPVKLCKGELPRthkt-pltFSCSNNNLTLFSITKQYTGTY 92  Simian adenovirus 23
Q3ZKT4    13 VTVAHGQTIVHITLGHNHTLVGPpITSEVIWT-KLGSVDYFDIICNKTEPIf-------VICNRQNLTLINVSKIYNGYY 84  Human adenovirus 50

Q6QPD0    94 YCPGQNTeeMIFYKVEVVDP 113 Simian adenovirus 23
ADP21162  83 YGTNYKN--SLDYNIIVVPA 100
P15139    83 YGTDYKS--SLDYNIIVLPS 100 Human adenovirus 35
Q4KSJ0   321 YGTNDKDe-SKRYRVKVNTT 339 Human adenovirus 46
Q91CB8   303 YGTDEKDk-ANRYRIKVNTT 321 Human adenovirus D8
Q80IV8   317 YGTNDRGh-SQRYRVKVNTT 335 Human adenovirus 8E
BAH19045 327 YGTNDKDe-GKRYRVKVNTT 345
Q6H1B4    94 YGTNFNTeqDTYYSVKVLDP 113 Human mastadenovirus E
Q6QPD1    93 YSTNFHTgqDKYYTVKVENP 112 Simian adenovirus 23
Q3ZKT4    85 YGYDRSSsqYKNYLVRITQP 104 Human adenovirus 50
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap