4BHM,5A4O


Conserved Protein Domain Family
PC4
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pfam02229: PC4 (this model, PSSM-Id:396692 is obsolete and has been replaced by 460501)
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Transcriptional Coactivator p15 (PC4)
p15 has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain. The DNA-binding activity of the carboxy-terminal is disguised by the amino-terminal p15 domain. Activity is controlled by protein kinases that target the regulatory domain.
Links
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Statistics
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PSSM-Id: 396692
Aligned: 162 rows
Threshold Bit Score: 35.1368
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4BHM_A                       16 DKRRVGISQFKKM-DFINIREYYEagGEMKpGKKGIGLTVDQYTAFLKA 63  Pyricularia oryzae
WP_015492566                 23 WKKELNLVSWNGRePKYDIREWSP--DGSK-MGKGITLSAEEAAVLKKA 68  Thermoplasmatales archaeon BRNA1
CDA73243                     22 WTKELNMVSWNERePKYDLREWNP--DHTR-MGKGITLTEEEVETLKKL 67  Ruminococcus sp. CAG:579
Q8Y9F0                       22 WRKELNKVSWNGRpPKYDIRDWSE--DHEK-MGKGITLTDEEAEVLKKL 67  Listeria monocytogenes
WP_014355807                 21 WQKELNLVSWNERdPKYDLRDWNA--DHEK-MRKGITLTTDELAQLRDI 66  Acetobacterium woodii
WP_013237283                 22 WKKELNLVSWNDRtAKYDIRDWSQ--EHDK-MGKGVTLTVDELRELKNI 67  Clostridium
AEB15231                     26 WNLELNFVSWGDRpAKYDIRSWDS--EHQK-MGKGVTFTKDELCALKNL 71  Treponema succinifaciens DSM 2489
csisp-ryc-ciber-uv:acin_0848 24 WTKEVNVISWNGGtPKYDIRDWTP--DHSK-MGKGVTLSVEEAVHLLKA 69  Acidaminococcus intestini RyC-MR95
EdlabUofT:DCF50_p1407        22 WTKELSLVSWNDKeAKYDIREWSP--EHDK-MGKGVTLSNEELKKLKEL 67  Dehalobacter sp. CF
EDK32587                     22 WKKELNLISWNNNaPKFDIRDWSP--EHTK-MGKGVTLTNEELKKLKDI 67  Clostridium kluyveri DSM 555
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