3N6W


Conserved Protein Domain Family
carnitine_bodg

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TIGR02409: carnitine_bodg 
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gamma-butyrobetaine hydroxylase
Members of this protein family are gamma-butyrobetaine hydroxylase, both bacterial and eukarytotic. This enzyme catalyzes the last step in the conversion of lysine to carnitine. Carnitine can serve as a compatible solvent in bacteria and also participates in fatty acid metabolism.
Statistics
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PSSM-Id: 274118
Aligned: 6 rows
Threshold Bit Score: 591.362
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3N6W_A    32 LMQILWYDEEESLYPAVWLRDNCPCSDCYLDS--AKARKLLVEALDVNIGIKGLIFDRKK--VYITWPDEHYSEFQADWL 107 human
AAR38130  17 ELVIDWQDGKQSRLFAHWLRDHCQMPTSRNLN--NGQRLFNVVDIPEETYIEKVYKDDKGnvCVLFQPENHLSIFSQNWL 94  uncultured marine b...
Q98KK0    13 TIELGWQGGRRTRFHAMWLRDNALDDKTRSAG--NGQRLITILDIPAETRIGAAEIKG-GalEVSFVPEGKTVSFPAQWL 89  Mesorhizobium loti ...
P80193    24 GVSVTWADGRVSPFHNLWLRDNCPCGDCVYEV--TREQVFLVADVPEDIQVQAVTIGDDGrlVVQWD-DGHASAYHPGWL 100 Pseudomonas sp. AK-1
O75936    16 LMQILWYDEEESLYPAVWLRDNCPCSDCYLDS--AKARKLLVEALDVNIGIKGLIFDRKK--VYITWPDEHYSEFQADWL 91  human
Q19000    27 IVNVKWSDGKTGVFPLIWLRDTSPDPSTYTISpaMTARKLTMLEFDVEQNARKLWIDEDAncLKIEWESGVLSEFPSEWL 106 Caenorhabditis elegans
3N6W_A   108 KKRCFSKQa--RAklQRELFFPECQYWG---SELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASD-KPGEVSKL 181 human
AAR38130  95 SKNCYDLN---LH--FDDRSERQKKLWQkdtFEAGLPFVDFESICNDVSSKLDMLRLIRDVGFVVLENVPT-KEGQVLKV 168 uncultured marine b...
Q98KK0    90 SANAYDRDe--LR--EPGWTGDVIQRWTkatMQNSVPRASYKAAFHGRSVLREWLSAVRTYGFAVMDGLPA-ESGALCKV 164 Mesorhizobium loti ...
P80193   101 RAHAYDAQs--LA--EREAARPHKHRWMq---gLSLPVYDHGAVMQDDDTLLEWLLAVRDVGLTQLHGVPT-EPGALIPL 172 Pseudomonas sp. AK-1
O75936    92 KKRCFSKQaraKL--QRELFFPECQYWG---SELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASD-KPGEVSKL 165 human
Q19000   107 KIRNPSDQearRR--RRKVYLFPEQTWGkaeIEGKLKKFSHEEFMKNEQVVHDFLQAVCIDGIAVLKGAPQgVRGAVEAI 184 Caenorhabditis elegans
3N6W_A   182 GKRMGFLYLTFYGHTWQVQDKIDANNVAYTT-GKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKN 260 human
AAR38130 169 ISELGYIRETNYGTLFEVRTEVNPNNLAYTN-MGLGSHTDNPYRDPVPTVQLLHCLESSTEGGDSVLVDGFKAAAVLRQE 247 uncultured marine b...
Q98KK0   165 SDLFGYIRETNYGRWFEVRAEVNPNNLAYTN-LGLQAHTDNPYRDPVPTLQILACVENTVEGGESSVIDGFAVAAALQAE 243 Mesorhizobium loti ...
P80193   173 AKRISFIRESNFGVLFDVRSKADADSNAYTA-FNLPLHTDLPTRELQPGLQFLHCLVNDATGGNSTFVDGFAIAEALRIE 251 Pseudomonas sp. AK-1
O75936   166 GKRMGFLYLTFYGHTWQVQDKIDANNVAYTT-GKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKN 244 human
Q19000   185 GDRIGMIKRTHFGLVFEVSLKADASNMAYASnGGLPFHTDFPSLSHPPQLQMLHMLQSAEEGGHSLFVDGFHVAEQLRVE 264 Caenorhabditis elegans
3N6W_A   261 NPQAFQILSSTFVDFTDIgVDYCDFsvQ-----------SKHKIIELDDKGQVVRINFNNATRDtIFDVPVERVQPFYAA 329 human
AAR38130 248 SKEDFDILTSTWINFRFS-DTKTDL--R-----------SRVPMIELNDNSEIVKVRYNNRSID-TINLPTNKIRSFYKA 312 uncultured marine b...
Q98KK0   244 NPEGFRLLSSCPARFEYAgSSGVRL--Q-----------AKRPMIELGPDGELICIRFNNRSLApVVDVPFADMDAYYAA 310 Mesorhizobium loti ...
P80193   252 APAAYRLLCETPVEFRNK-DRHSDY--R-----------CTAPVIALDSSGEVREIRLAN-FLRaPFQMDAQRMPDYYLA 316 Pseudomonas sp. AK-1
O75936   245 NPQAFQILSSTFVDFTDIgVDYCDF--Sv---------qSKHKIIELDDKGQVVRINFNNATRDtIFDVPVERVQPFYAA 313 human
Q19000   265 KPEIFKILTTQSMEYIEEgYDVHEI--NgktirfdydmcARHKVIRLNDDGKVNKIQFGNAMRSwFYDCEPSKVQDVYRA 342 Caenorhabditis elegans
3N6W_A   330 LKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEagTEISRHLEGAYADWDVVMSRLRILRQ 397 human
AAR38130 313 YRHWSEIIERDNLKVIFKLSEGDLMLIDNTRIMHARTAFS--KKGKRHLQGAYTDLDGLYSQLNALKN 378 uncultured marine bacterium 578
Q98KK0   311 YRRFAELIEDPDFEVTFKLQPGQAFIVDNTRVMHARKAFS--GTGKRWLQGCYADKDGLLSTLAAIEH 376 Mesorhizobium loti MAFF303099
P80193   317 YRRFIQMTREPRFCFTRRLEAGQLWCFDNRRVLHARDAFDp-ASGDRHFQGCYVDRDELLSRILVLQR 383 Pseudomonas sp. AK-1
O75936   314 LKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEagTEISRHLEGAYADWDVVMSRLRILRQ 381 human
Q19000   343 MKTFTEYCYQPRNMLKFRLEDGDTVLWANQRLLHTRDGFRnaPEKARTLTGCYFDWDIVKSRVRFLRD 410 Caenorhabditis elegans
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