Conserved Protein Domain Family
Pacifastin_I

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pfam05375: Pacifastin_I 
Pacifastin inhibitor (LCMII)
Structures of members of this family show that they are comprised of a triple-stranded antiparallel beta-sheet connected by three disulfide bridges, which defines this as a novel family of serine protease inhibitors.
Statistics
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PSSM-Id: 253170
Aligned: 36 rows
Threshold Bit Score: 34.2863
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8T0W2 149 SCAPGASFKYYCNSCTCGAEGKvaeAQCTSQECDRykwkkdGS 191 Pimpla hypochondriaca
P91776 387 QCTEGESWRQDCNMCSCS-TGL---RICSVKGCPPt-----PT 420 signal crayfish
O46163  23 ACTPGSRKYDGCNWCTCSSGGA---WICTLKYCPPssggglTF 62  Schistocerca gregaria
Q19Q50  44 NCENGESYFDGCNTCTCK-NGA---YSCTLKACYTgpllpdTA 82  Belgica antarctica
P80060  22 KCTPGQVKQQDCNTCTCTPTGV---WGCTRKGCQPakreisCE 61  migratory locust
Q8MYK3  24 ECTPGETKKLDCNTCFCSDSGI---WGCTLMGCRTytlqpaPT 63  Schistocerca gregaria
Q8WQ21  24 ECTPGETKKLDCNTCFCTKAGI---WGCTLMACRTinieltPG 63  African migratory locust
Q5K4F7  25 GCTPGEKKKEDCNTCTCTATGV---WACTRRGCITkreaeeSP 64  Schistocerca gregaria
Q8WQ22  25 ECTPGQTKKQDCNTCTCTPTGI---WGCTRKACRTtreaeePA 64  African migratory locust
O46162  22 ECTPGQTKKQDCNTCNCTPTGV---WACTRKGCPPhkrevtCE 61  Schistocerca gregaria
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