Conserved Protein Domain Family
near_not_gcvH

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TIGR03076: near_not_gcvH 
Chlamydial GcvH-like protein upstream region protein
The H protein (GcvH) of the glycine cleavage system shuttles the methylamine group of glycine from the P protein to the T protein. Most Chlamydia but lack the P and T proteins, and have a single homolog of GcvH that appears deeply split from canonical GcvH in molecular phylogenetic trees. The protein family modeled here is observed so far only in the Chlamydiae, always as part of a two-gene operon, upstream of the homolog of GcvH. Its function is unknown. [Unknown function, General]
Statistics
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PSSM-Id: 213771
Aligned: 3 rows
Threshold Bit Score: 1234.37
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010230829   2 LAFFNKHQKKFIGLVIAGVCLSGVGVGIGQTFKKTQkFGSNK-TVYKTPsGRKYSEKEFFLLKRFLSNEAYPFTGNPKEW 80  Chlamydia murid...
WP_011097006   4 LAFFYKHQKKFMGFVIVGVCVSGIGIGWGRYPGESS-RGSKK-IVFSVP-GKKYSEREFLAFKRFFTNEAYPFTGNPQAW 80  Chlamydophila a...
WP_010883077  39 LSFFYKHQKKFIGIVIAVVCVSGIGVGWGRFSRKGSaESTSRrTVFTTAsGKRYVEKDFMAMKKFFAHEAYPFTGNPRAW 118 Chlamydia pneum...
WP_010230829  81 NFLNEGVLTERFLTNKLGEKLFLSVYKSGFPAFDKERSYEGYRRFDAPFISSEEVWKSSAPQLRDAFHIFQQLENPVSPE 160 Chlamydia murid...
WP_011097006  81 NFLNEGLLTERFLTNKLGEKLFLKVYSQDYPAFKKEKNYQSYRRFDSLFISSEEVWKSSAPRLYQALVALQEIHDPVSPE 160 Chlamydophila a...
WP_010883077 119 NFINEGLLTDYFLTTRVGEKLFLKVYHPGEKIFSKEKAYQPYRRFDAPFISSEEVWKSSAPQLLEILKVFQQIENPISKE 198 Chlamydia pneum...
WP_010230829 161 GFAARVRLFLEEKKFPHYVLRQMLEYRRQMFNLPVDGSLAQGRDLRLFGYRNIKDWFGDRYVSAVTEAVLRFIDEQKKNI 240 Chlamydia murid...
WP_011097006 161 GFVARVQLFLEEKKFPHYILKQMLEYRRQMFNLPQDPVLAQGKDLHLFGYRNIADWFGDAYVSAAVEALLRFVNEQKKNV 240 Chlamydophila a...
WP_010883077 199 GFLARAKLFLEERRFPHYVLRQMLEYRRQMFALPPDEALSRGKDLRLFGYQTIQDWFGDAYLSAAVELLIRFIDEQKKVL 278 Chlamydia pneum...
WP_010230829 241 AMPSLKEAQQDFYDKAQQAFLRLSRHAEFNLTLDQLVSSFYSFMGVEEAEFIRMYREILLYKRALLALEGAVAFDFYPLQ 320 Chlamydia murid...
WP_011097006 241 AMPSLKEAQQDFQDKAKQAFTKLSKHAGLTLSFDQFVASYFDFMGVSESEFFNIYREILLCKRAFLQLEGSVTFDYRPLQ 320 Chlamydophila a...
WP_010883077 279 PRPSKQEARDDFYDKAKHAYTKISKNKEFSLGFEEFVNSYFQFLEISESEFFNMYRDILLCKRALLLLQGGVSFDFQPLT 358 Chlamydia pneum...
WP_010230829 321 KFFSMGKDTVSVEMFHLPETLVFKDKEDLEAFETYLSLVAAPSSHILDVQTKLLPIEKVKSKAECLVGKRFSVCYRRVKL 400 Chlamydia murid...
WP_011097006 321 EFFSMGKDSTSVEMVKLPREYQFKNKEDLEAFEVYISLVGEPIKDCLSVPRCTLPIKTIKAKEPRLVGRRFLVSYKSVKL 400 Chlamydophila a...
WP_010883077 359 TFFVQGKDSIQVEFFRLPKEYSFKTKQELKAFEVYLKLVSLPKSDSLDVPNEILPIATIKAKEPRLVGRRFSIDYKRVAL 438 Chlamydia pneum...
WP_010230829 401 SELEKYIPMAQVYQWYQNPENFEEILLEFPELETCSSLRDVLNLKPAIVERAHSYVRKAILRADLGIIQSELAKQEQKEE 480 Chlamydia murid...
WP_011097006 401 QDLETKVPMVEVHQWQQNPENFQVLLQQFPKIETCNSSKDFQTLKPSLVEKIYSFTRKEILRSSPKRILEGLAQCEQKSH 480 Chlamydophila a...
WP_010883077 439 QDLAATVPMVEVLHWQQNSEHFQEILQQFPDVETCQSYKDFQHLKPALRDKISLFTRKEILRARPERILQSLQQVPKQSQ 518 Chlamydia pneum...
WP_010230829 481 ELFLSLGPDHLLPGIQNGVRLANVLMQQDSVDYYTQDDEYFYSIIVKNRTGTDEVLPYKEVVRKGLKKVLLERYKAEERI 560 Chlamydia murid...
WP_011097006 481 EVFLSARKDSVLEGILDGNELAKLLLDNEVLEAYSQDGEHYYTFVVDTCFEGEEVIPYREVLRKGLAKTLVSSHKNIAHI 560 Chlamydophila a...
WP_010883077 519 EVLLSAGKNSALPGISDGQQLAKVLLENEVLDLYSQDAETYYTIIVNSSFEKEEVLPYREVLKRDLASQLLTSHGHLVDM 598 Chlamydia pneum...
WP_010230829 561 TRVLAHLQEAFPNCQGKDLYQRRLIRFVKSLQSGRFSQGDLFWGLEKTVKTFSRGDQGVPQEFEEMLALKEGQVSDVLFD 640 Chlamydia murid...
WP_011097006 561 DRVVAALKSRYQEEENSNLWQKRLWLLVEEHREGTYQPGALSWNLEKSIKVFTRGDQNIPQPYPVLASMEEGALSGVEFN 640 Chlamydophila a...
WP_010883077 599 ERLESALRTRYPGEEGASLWQRRLWKVVENHRLGRHLEGSFSWSLDRSLKTFSRGDKELPQEFDRIFSMKVGDYSSVFMS 678 Chlamydia pneum...
WP_010230829 641 SDKGPFYYTFISKTYCDYPVSLDKLLFAKNHLNEELLRPYLSEiFFQN 688 Chlamydia muridarum
WP_011097006 641 PDEGPFFYKCLSHQTCMEPTSVEKLFLTKNHLNEEILGSYIEH-FIDE 687 Chlamydophila abortus
WP_010883077 679 PNEGPCYYQCLSHLLYDRPASVDKLFLAKSQLDEELLGSYMER-FIEQ 725 Chlamydia pneumoniae
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