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Betacoronavirus NS7A protein This entry corresponds to the Human SARS virus NS7A protein (also known as 7a, accessory protein 7a, X4 and U122). The structure of this protein shows similarities to the immunoglobulin like fold and a known member of the immunoglobulin (Ig) domain superfamily, which suggests a binding activity to integrin I domains. In SARS-CoV-infected cells, the NS7A protein is expressed and retained intra-cellularly within the Golgi network. NS7A has been implicated to function during the replication cycle of SARS-CoV. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",