2N0S


Conserved Protein Domain Family
Fe_hyd_lg_C

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pfam02906: Fe_hyd_lg_C 
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Iron only hydrogenase large subunit, C-terminal domain
Statistics
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PSSM-Id: 397172
Aligned: 137 rows
Threshold Bit Score: 188.596
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2N0S_A            30 KHVCVQVAPAVRVAIAETLGLAPgATTPKQLAEGLRR-LGFDEVFDTLFGADLTIMEEG--SELLHRL---------TEh 97   Chlamydomo...
Q5RF36           110 RLVVVSVSPQSRASLAARFQLNP-TDTARKLTSFFKK-IGVHFVFDTAFSRHFSLLESQ--REFVRRFrg-----qaDC- 179  Sumatran o...
Q16ML2           112 RYIVFTVAQQPILSLAKRYNLGP-EETFERVAGYFKK-LGADMVVDTKIADDLSLIESR--NEFVERFn-------tN-- 178  yellow fev...
jgi:OSTLU_33837  106 SVVVASVSPQSLMSLSEAYGLGV-EETRARLGGLLKAgFGAARAFDTSFSRDIALVETF--AEFTEWMr-------dGa- 174 
Q4D686            88 RPFLVTISDQSAASIAAHLKVDS-RRAFHIISGFFRTvLKSQYVSDLRWAQHISVEKTA--QEYCHRLq--------HA- 155  Trypanosom...
A0DWM5           705 QNPAIGISPQSRASLSHVLNFTD-SEMHSILHQLFQE-LNVK-LYDMSEYMKIAINNSI--QEFKQ-------------- 765  Paramecium...
A7TQP0            87 YILSVSIAPQCRVSLSQYFGMGV-LKFDQMFIRYLQEvWGARYVVGIQEGREESIKLMNevADKGERK------------ 153  Vanderwalt...
Q75E78            89 KALAVSVAPQSRLSLAQHFGLSV-AELDQCLSGVLGSyFGAKYVVGTQLGRELSVQQTN--ARLVERKq-------qGv- 157  Eremotheci...
Q94CL6            92 KDVVVSVSPQSRASLAVHYDISP-LQVFKKLTTFLKS-LGVKAVFDTSCSRDLVLIESC--NEFVSRYkqansddgeNS- 166  thale cress
Q93YF9            94 KAVIVSVSPQSRTSIATHFGISA-VQAFKKLTRFFKS-LGVRAIFDTSCSRDLTLVESC--VEFITRYrqnqlvddeRS- 168  barrel medic
2N0S_A            98 leahphsDePLPMFTSCCPGWIAMLEKSYPD-LIPYVSSCKSPQMMLAAMVKSYLAEKkgiapkdMVMVSIMPCTRKQSE 176  Chlamydomo...
Q5RF36           180 -------KqALPLLASACPGWICYAEKTHGSfILPHISTARSPQQVMGSLVKDFFAQQqhltpdkIYHVTVMPCYDKKLE 252  Sumatran o...
Q16ML2           179 -------RqSMPMMASSCPGWVCYAEKTHGNfILPFIATTRSPQQIMGVLVKKYLAKIlgvpgdrIYHVTVMPCYDKKLE 251  yellow fev...
jgi:OSTLU_33837  175 ---------RTPMLASACPGWVCYAEKTHGElAVPHMATTKSPQQIMGRFVKSAVARElgvpahnVYHVSVMPCYDKKLE 245 
Q4D686           156 -------RdKLPMIVSACPGWVCYCEKQGSA-ILPLLCPVMSPQGIAGCYAKRV-FPQ-------LCHISVQPCFDRKLE 219  Trypanosom...
A0DWM5           766 -------TkITPLLCSECPGWVCYAEKTLDEsIINHMSKVKSPQQIFGAILKKn----------hDYIATIMPCYDKKLE 828  Paramecium...
A7TQP0           154 -------------ICSACPGFLMYCEKKQQD-LLPLLIDVKSPMEITGHLL--KDGNKe-----kMYHLSIMPCFDKKLE 212  Vanderwalt...
Q75E78           158 ---------QGPLLCSVCPGFVLYAEKTKPG-LVPYMLDVKSPQQITGALLHAADPN--------IYHLSLMPCFDKKLE 219  Eremotheci...
Q94CL6           167 -------QsPLPVLSSACPGWICYAEKQLGSyVLPYVSSVKSPQQAIGAAIKHHLCQAlglrlheVYHVTVMPCYDKKLE 239  thale cress
Q93YF9           169 -------KsSLPMIASACPGWICYAEKQLGSfVLPYISSVKSPQQTIGTIIKRYVCQDmelrpeeVYHVTVMPCYDKKLE 241  barrel medic
2N0S_A           177 ADRDWFCVd------Adp----tlRQLDHVITTVELGNIFK------------ERGINL-----AELPEGEWDNPMGVGS 229  Chlamydomo...
Q5RF36           253 ASRPDFFNqe----hQt-------RDVDCVLTTGEVFRLLE------------EEGVSL-----PDLEPAPLDSLCSGAS 304  Sumatran o...
Q16ML2           252 ASREDFFSdv----dNc-------RDVDCVITSIEIEQMLD------------GTGIQFl----QTVEPSPID------- 297  yellow fev...
jgi:OSTLU_33837  246 ATRDDFESd------Gv-------KDVDVVLTTGEVALLLE------------KAGLCHl----RDAPANDFDAFVS-TN 295 
Q4D686           220 AARDTSIDg------Ne-------RYTDFVLSTQELMEWMMetdasipweaplNSSFEF----------LPPPLLKESSS 276  Trypanosom...
A0DWM5           829 AVRLEN---------N--------EDINIVLSTREIEQYIK----------------DYi----QKSQITPQQTQLSTMA 871  Paramecium...
A7TQP0           213 SMRPES---------I--------GLVDCVITPKELVNLIT------------PEQVDKyf-atTKETIGMLEWEDAIQR 262  Vanderwalt...
Q75E78           220 AAREDC---------A--------REVDCVLTPREFVALLD------------ELQLDLhsfagAAVPIAQL-------- 262  Eremotheci...
Q94CL6           240 AARDDFVFddgtqdnGdl----klTEVDSVLTTGEIMDLIK------------LKGVDF-----KDLEESPLDRVLTNVT 298  thale cress
Q93YF9           242 ASRDDFVFqldphaeGhegevnmiSEVDSVLTTGEILELIQ------------SKEVDF-----KSLEEAPLDKLLTNVN 304  barrel medic
2N0S_A           230 GAGVL-----------FGTTGGVM-EAAL--RTAYELF-------T-GTPLPR-LSlsEVRGM---DGIKETN-----It 278  Chlamydomo...
Q5RF36           305 AEEPTsh--------rGGGSGGYL-EHVF--RHAAREL-------F-GIHVAE-VTykPLRNK----DFQEVT-----Le 355  Sumatran o...
Q16ML2           298 WPWPTprpsafvwaheSSGSGGYS-EYIF--KYAARKL-------F-NINIDQ-AEfkILRNN----DLREAI-----Le 356  yellow fev...
jgi:OSTLU_33837  296 EQAPEsvca----apaVSGSGGYA-EYVF--RRAAAEL-------F-NAPITGeIDwvKMRNA----DMREAT-----Lt 351 
Q4D686           277 VLAAN-----------MEGSGGYH-------RFAMQYVaenvhnlSfSRDDIL-----YEMKRnanHHVATSPsnpgeV- 332  Trypanosom...
A0DWM5           872 INFQEyh--------nIS-SNNYL-DYII--QSSVKPN-------W------T-VKqnIRKNK----DFIEITiynedMq 921  Paramecium...
A7TQP0           263 VTPKWmnidtsfktneGSSSGGFAwQYILh-RRFQMSD-------N-DNDNAYkIEtvRGRNL----DVTEFRl----Id 325  Vanderwalt...
Q75E78           263 -TPPGwdprvswcssaGSSSGGYAyQYILhmQRLHPGS-------T--------IAtqAGRNA----DLLEHRl----La 318  Eremotheci...
Q94CL6           299 EEGDLyg--------vAGSSGGYA-ETIF--RHAAKAL-------F-GQTIEGpLEfkTLRNS----DFREVT-----Lq 350  thale cress
Q93YF9           305 EEGDLyg--------vRGSSGGYA-ETIF--RYAAKTL-------F-GRHIDGpLDfrNIRNS----DFQEVT-----Le 356  barrel medic
2N0S_A           279 mvpapgskfeellkhraaaraeaaahgtpgplawdggagftsedgrggitlrVAVANGLGNAKKLITKM----------- 347  Chlamydomo...
Q5RF36           356 kegq--------------------------------------------vllhLAMAYGFRNIQNLVQRL----------- 380  Sumatran o...
Q16ML2           357 inge--------------------------------------------vllrFAIANGFRNIQNMVQKL----------- 381  yellow fev...
jgi:OSTLU_33837  352 inge--------------------------------------------avlrVAVAYGFRNIQNLVRSI----------- 376 
Q4D686           333 ----------------------------------------------------YCVAYGFQHIQNIVRGL----------- 349  Trypanosom...
A0DWM5           922 lq------------------------------------------------giYARVFGLKNIANLISQI----------- 942  Paramecium...
A7TQP0           326 eegk--------------------------------------------ilvrSTQVFGFRNIQNL-RRLvkdvkprklkr 360  Vanderwalt...
Q75E78           319 psgv--------------------------------------------llasAGELYGFRNIQNLVRKLlspatkrsakv 354  Eremotheci...
Q94CL6           351 legk--------------------------------------------tvlkFALCYGFQNLQNIVRRV----------- 375  thale cress
Q93YF9           357 vege--------------------------------------------tvlkFALCYGFRNLQNTVRKL----------- 381  barrel medic
2N0S_A           348 ---------------------------------QAGEAKYD---FVEIMACPAGCVGGG 370  Chlamydomonas reinhardtii
Q5RF36           381 ---------------------------------KRGRCPYH---YVEVMACPSGCLNGG 403  Sumatran orangutan
Q16ML2           382 ---------------------------------KRGKCNYH---FIEIMACPSGCLNGG 404  yellow fever mosquito
jgi:OSTLU_33837  377 ---------------------------------KLKKSKHH---FVEIMACPSGCLNGG 399 
Q4D686           350 ---------------------------------KRKLASVSsytFIELMACPDGCLNGG 375  Trypanosoma cruzi
A0DWM5           943 ---------------------------------KTKTCKYK---YVEIMACPLGCLNGG 965  Paramecium tetraurelia
A7TQP0           361 firkrptangndnsislsssinnqdnnntkveePVDFCKSD---FLEVMACPRGCIAGG 416  Vanderwaltozyma polyspora DSM 7...
Q75E78           355 v--------------------rrrlpqaspappATDPCNAD---FIEVMACPSGCINGG 390  Eremothecium gossypii ATCC 10895
Q94CL6           376 ---------------------------------KTRKCDYQ---YVEIMACPAGCLNGG 398  thale cress
Q93YF9           382 ---------------------------------KTGKYDYH---FLEIMACPSGCLNGG 404  barrel medic
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