6TMR


Conserved Protein Domain Family
Rhabdo_glycop
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pfam00974: Rhabdo_glycop 
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Rhabdovirus spike glycoprotein
Frequently abbreviated to G protein. The glycoprotein spike is made up of a trimer of G proteins. Channel formed by glycoprotein spike is thought to function in a similar manner to Influenza virus M2 protein channel, thus allowing a signal to pass across the viral membrane to signal for viral uncoating.
Links
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Statistics
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PSSM-Id: 425969
Aligned: 4 rows
Threshold Bit Score: 632.402
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6TMR_A   1 E-------------FPLYTIPE--KIEKWTPIDMIHLSCPNnlLSEEEGCNAESSFTYFE-LKSGY-LAHQKVPGFTCTG 63  Mokola lyssavirus
P08667  20 K-------------FPIYTIPD--KLGPWSPIDIHHLSCPNnlVVEDEGCTNLSGFSYME-LKVGY-ISAIKMNGFTCTG 82  Rabies virus strain P...
P03522   3 cllylaflfigvnckftIVFPHnqK-GNWKNVPSNYHYCPS---SSDLNWHNDLIGTAIQ-VKMPKsHKAIQADGWMCHA 77  Vesicular stomatitis ...
Q82683  24 KpdtasesdqptwsNPLFTYPEgcTLDKLSKVNASQLRCPR--IFDDENRGLIAYPTSIRsLSVGNdLGDIHTQGNHIHK 101 Infectious hematopoie...

6TMR_A  64 VVNEAETYTNGNGSVTTTFKRKHFRPTVAACRDAYNWKVSGdpryeeSLHTP--YPDSSGSRTVTTTKESLLIISPSIVE 141 Mokola lyssavirus
P08667  83 VVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGdpryeeSLHNP--YPDYHWLRTVKTTKESLVIISPSVAD 160 Rabies virus strain P...
P03522  78 SKWVTTCDFRWYGPKYITQSIRSFTPSVEQCKESIEQTKQG------TWLNPgfPPQSCGYATVTDAEAVIVQVTPHHVL 151 Vesicular stomatitis ...
Q82683 102 VLYRTICSTGFFGGQTIEKALVKMKLSTKEA-GAYDTTTAA------ALYFP--APRCQWYTDNVQNDLIFYYTTQKSVL 172 Infectious hematopoie...

6TMR_A 142 MDIYGRTLHSPMFPSGVCSNvypsvPSCETNHDYTLWLpEDPSLSLVCD--------IFTSSNG----KKAMNGSRICGF 209 Mokola lyssavirus
P08667 161 LDPYDRSLHSRVFPGGNCSGvavssTYCSTNHDYTIWMpENPRLGMSCD--------IFTNSRG----KRASKGSETCGF 228 Rabies virus strain P...
P03522 152 VDEYTGEWVDSQFINGKCSN-----YICPTVHNSTTWH-SDYKVKGLCDsnlismdiTFFSEDG----ELSSLGKEGTGF 221 Vesicular stomatitis ...
Q82683 173 RDPYTRDFLDSDFIGGKCTK-----SPCQTHWSNVVWM-GDAGIP-ACDssqeikahLFVDKISnrvvKATSYGHHPWGL 245 Infectious hematopoie...

6TMR_A 210 KDERGFYRSLKGACKLTLCGRPGIRLFDGTWVSFTKPDVHV-----WCTPNQLINIHNDRLDEIEHLivEDIIKK---RE 281 Mokola lyssavirus
P08667 229 VDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETK-----WCPPGQLVNLHDFRSDEIEHLvvEELVKK---RE 300 Rabies virus strain P...
P03522 222 RSNYFAYETGGKACKMQYCKHWGVRLPSGVWFEMADKDLFAaarfpECPEGSSISAPSQTSVDVSLI--QD-VERildYS 298 Vesicular stomatitis ...
Q82683 246 HQ----------ACMIEFCGQQWIRTDLGDLISVVYNSGSEilsfpKC-EDKTVGMRG-NLDDFAYL--DDLVKAsesRE 311 Infectious hematopoie...

6TMR_A 282 ECLDTLETILMSQSVSFRRLSHFRKLVPGYGKAYTILNGSLMETNVYYKRV--------------------------DKW 335 Mokola lyssavirus
P08667 301 ECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSV--------------------------RTW 354 Rabies virus strain P...
P03522 299 LCQETWSKIRAGLPISPVDLSYLAPKNPGTGPAFTIINGTLKYFETRYIRVdiaapilsrmvg--misgttterelwDDW 376 Vesicular stomatitis ...
Q82683 312 ECLEAHAEIISTNSVTPYLLSKFRSPHPGINDVYAMHKGSIYHGMCMTVAVdevskdrttyrahratsftkwerpfgDEW 391 Infectious hematopoie...

6TMR_A 336 ADilpskgclkvgqqcmepvkgvlFNGIIKGPDGQILIPEMQS---EQLKQHM---DL-LKAAVFPLRHPLISREAVFKK 408 Mokola lyssavirus
P08667 355 NEiipskgclrvggrchphvngvfFNGIILGPDGNVLIPEMQS---SLLQQHM---EL-LVSSVIPLMHPLADPSTVFKN 427 Rabies virus strain P...
P03522 377 AP----------------------YEDVEIGPNGVLRTSSGYKfplYMIGHGMldsDLhLSSKAQVFEHPHIQDAASQLP 434 Vesicular stomatitis ...
Q82683 392 EG----------------------FHGLH--GNNTTIIPDLEK---YVAQYKM---SMmEPMSIKSVPHPSI-------- 433 Infectious hematopoie...

6TMR_A 409 DGDADDFVDLHMPDVH-KSVSDVDLGLPH 436 Mokola lyssavirus
P08667 428 GDEAEDFVEVHLPDVH-ERISGVDLGLPN 455 Rabies virus strain Pasteur vaccin
P03522 435 DDESLFFGDTGLSK---NPIELVEGWFSS 460 Vesicular stomatitis Indiana virus strain San Juan
Q82683 434 ---LALYNETDVSGISiRKLDSFDLQSLH 459 Infectious hematopoietic necrosis virus - WRAC
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