5FU6,4C0D,5FU6,4BY6


Conserved Protein Domain Family
NOT2_3_5

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pfam04153: NOT2_3_5 
NOT2 / NOT3 / NOT5 family
NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.
Statistics
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PSSM-Id: 461199
Aligned: 168 rows
Threshold Bit Score: 88.4243
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5FU6_C        20 AAWHHMPHPSDSERirQ--YLP--RNPCPTPpyhhQMPP-PhSD-TVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKK 93 
XP_015789988 290 YSTFCGPWSDQPLK--P--HEMdyPVPHEYL----IN-SqIrEKlLPIKLSRYGDDTLFFLFYMFPNDLIQIAAASELYS 360
XP_009017059  47 YTSFQSPWSELPCK--P--QDIdyHVPNEYL----TN-IfVrEKlAPLRLNRYSDDLLFFLFYLYSGDLLQLAAAAELYN 117
EDS29667     420 YPSFGGPFADSPAR--P--QDIdyNVPPEYL----IN-MsIrDKlSKLTLQKYKDDLLFYLFYTNVGDVMQLAAAAELHS 490
XP_002056615 429 HPTFAGPFVEQPCR--A--QDVeySVPPEYL----IN-FaIrDKlTAPVLKKLQEDLLFFLFYTNIGDIMQLMAAAELHS 499
XP_016661188 450 YPTFAGPFENSPLE--P--HNIefDVPSEYK----IH-HkIkNKlAPIKFSEYQEDLLFYLFYTHFGDGIQMAVASELRT 520
XP_002079535 289 dsIFTRPIQEAPLT--P--QEMnyQLPLNY-------LFnAnMHlQEPKIEEMQDELLFFFFYTYTGDMMQMLAAAELAE 357
XP_002052153 324 HACFAGPLQGGRCA--PheVNY--DVPLHYR----RAGGqDlPQ-P--KIDQMEVELLFFFFYTYPGDMMQMLAAAELAE 392
EFP02136     145 HRSFGGPWADSPIR--A--HELdvKVPEEYM----TH-NhIrDKlPPLRLSKVSEDVLFYLFYNCPNEIYQVAAACELYN 215
XP_019861520   9 YSTFSSPFADSPSR--P--QDIdyPVPQEYL----IH-SyIrDKlAPIRLSKYNEDLLFYLYYTSGGDLLQLLAAHELYT 79  Amphimedon quee...
5FU6_C        94 QSWRFHTKYMMWFQRHe--EPKTITDEF-EQGTYIYFD-YeKWGQRKkEGFTFEYR 145
XP_015789988 361 RDWRYHKDEKVWITRApgmPPIEKSQNY-ERGTYYFFDaS-SWRRVA-KEFHLDYD 413
XP_009017059 118 RDWRYHKDERLWMTRApgmEPTVKTNQF-ERGTYFFFDvN-NWRKVP-KDFLLEYN 170
EDS29667     491 RDWRYHTEEKVWITRVpgmTPYEKNGTT-ERGTYYYFDaQ-NWRRVP-KEFQVDTV 543
XP_002056615 500 REWRYHVEEKIWITRIpgiNQYEKNGTK-ERGTFYYFDaQ-SWKRLS-KVFQIDAE 552
XP_016661188 521 RGWRYHTGQHIWITPVcrsSTSEINGKF-ERGTFYVFDvA-LWRKVP-RELMLDHT 573
XP_002079535 358 RGWRYHKFERVWLIRQa-dNPNYLYHGFrEFGEYNYFNmW-QWKILP-RHFYLDPE 410
XP_002052153 393 RGWRFHIYERLWIRRQa-dNPHYVICGYqESGEYNYFN-MvHWKILA-RHFDLMPE 445
EFP02136     216 REWRFHKSEQVWLTRSqygGVKEQTGQY-EKGHYNVFDqM-QWRKIP-KELKLEYK 268
XP_019861520  80 RDWRYHKEEKIWITRApnmRPTKVETTY-EEGTYCYFDlG-TWRKAH-RDMKVEYD 132 Amphimedon queenslandica
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