Conserved Protein Domain Family
C11orf65

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cd21090: C11orf65 
chromosome 11 open reading frame 65 and homologs
Chromosome 11 open reading frame 65 (C11orf65) is an uncharacterized protein that may be associated with potential sensitivity to metformin in type 2 diabetes (diabetes mellitus) patients without cancer.
Statistics
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PSSM-Id: 411042
Aligned: 18 rows
Threshold Bit Score: 451.392
Created: 23-Dec-2019
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8NCR3         9 FTKQDKAARVIQQAWKSFLNVAIFqhFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGIHVRFRlggVKFPPDIYYKIF 88  human
NP_083523      9 NSNQEIAARIIQRAWKTFLNVSVYqhFKSLIDLRRQGEPRQIVRYINPKEAQLLDAAAGVQVRFRlggVRFPPEIYYKIF 88  Mus musculus
NP_689800      9 FTKQDKAARVIQQAWKSFLNVAIFqhFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGIHVRFRlggVKFPPDIYYKIF 88  Homo sapiens
XP_007903826 130 ETEVDNAARIIQKAWRRFIDKLLFryYKELINFKGKGEPRILMKSINPIEAAYLDAAAGVHIRFRlggESFPPDIYYKIF 209 Callorhinchus m...
XP_001381470  11 FEGYDKAARIIQKAWKNYLDICVFshFRNLIYIRRQGDPHQLLKYIDPKEAELIDAASGINIRFRlggEKFPPCIYYKIF 90  Monodelphis dom...
XP_002126507 137 ISNKSDAASVIQRSWRRHIDMQVFryYRDLINFRGHGDPALMLKCINPNESKLLDSAAGVHVRFRlagEKFPPNIYYKIF 216 Ciona intestinalis
NP_001019436   9 HSKQEMAARIIQKAWKTFLNVSVFqhFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGVQVRFRlggVKFPPEIYYKIF 88  Rattus norvegicus
Q569B9         9 HSKQEMAARIIQKAWKTFLNVSVFqhFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGVQVRFRlggVKFPPEIYYKIF 88  Norway rat
XP_007059758   5 EDKRNHAARVIQRCWKRCINVRVFryYKELIGFRGVGDPHLLMKCIDPREAELLDAAAGVYIRFRlggTKYPPSIYYKIF 84  Chelonia mydas
XP_002934975  13 TAERERAARVIQRAFRRILDIQIFqfYKNLLSFKGKGDPRLLLKCVNPCEAELIDAAAGVHARFRlggTQFPPNIYYKLF 92  Xenopus tropicalis
Q8NCR3        89 THRPIEDLCANSPRNYAKlp----aKHTSHNKnd-hLQEEDHSGWYHRIENNGWRPVSDTfwlstd--gmvveDKKESEF 161 human
NP_083523     89 THRHIEDLCANSPRDYTKlp----aRYTSHNKdd-pPQVEDNSGWYRRVENNGWRPVSYRfwmple--sgvvdSTKESEF 161 Mus musculus
NP_689800     89 THRPIEDLCANSPRNYAKlp----aKHTSHNKnd-hLQEEDHSGWYHRIENNGWRPVSDTfwlstd--gmvveDKKESEF 161 Homo sapiens
XP_007903826 210 THRPIVDICANSPKNYTNpaakqqvPRQLHNRw--eIMEDDQSGWYKRVEMNGWRRLSHRiilks---vylqsKENAIEF 284 Callorhinchus m...
XP_001381470  91 THRNIVDLCANSPRDYVNvi----pKRLAHLPff-kNLKDDHRGWYQRVENNGWRLVSKRfwrasd-eiteegNRQKVNF 164 Monodelphis dom...
XP_002126507 217 THRPVVDMCANSPKDYTKieakvpvGKQVHNKtlslNTTNTKEGWYVRHENNGWRLVSDRlihssmdpvtwqtSKKTVDF 296 Ciona intestinalis
NP_001019436  89 THRHIEDLCANSPRDYTKlp----aRYASHNKdd-pPQVEDNSGWYRRIENNGWRPVSNRfwmpte--nevleSTKESEF 161 Rattus norvegicus
Q569B9        89 THRHIEDLCANSPRDYTKlp----aRYASHNKdd-pPQVEDNSGWYRRIENNGWRPVSNRfwmpte--nevleSTKESEF 161 Norway rat
XP_007059758  85 THRPIVDMCANSPKDYTKpaykqllPEAIHGK----IWKDDRNGWYKRVENNGWRLLSIRfwrtid-pitaedNIKEKEF 159 Chelonia mydas
XP_002934975  93 THRPIVDMCANSPKDYTQnclkqllPKQMHNRg--lVPKQDLSGWYARVENNGWRLLTPRishsld-lvtiadSRKRIPF 169 Xenopus tropicalis
Q8NCR3       162 HFSKLKRRQDLEKKRKLRKIEWMRQMYYSGSLEAKSTHHETLGLIHTATKGLIRAFEDGGIDSVMEWEVDEVLNWTNTLN 241 human
NP_083523    162 HFSKLKRKQDLEKKRKIKKIDWMRQMYYMGSLEAKATDNETLGLIHKATKGLIKSIEDGGVDSVMEWEVDEVLNWTNTLN 241 Mus musculus
NP_689800    162 HFSKLKRRQDLEKKRKLRKIEWMRQMYYSGSLEAKSTHHETLGLIHTATKGLIRAFEDGGIDSVMEWEVDEVLNWTNTLN 241 Homo sapiens
XP_007903826 285 HHSKRHRREEMQKQRKDKKIKWMQMMYHGNMLEAQTTDPFIVDLVQNATIGLMNMVEKEGYDTALEWEVDELLEWTNALN 364 Callorhinchus m...
XP_001381470 165 PFSKMMRKQDFEKRRKYKKIQWMREMYYAGNLETKRADNRCTDLILKATKGLMRAVEQGGMKSVMEWEVDEILSWTNALN 244 Monodelphis dom...
XP_002126507 297 HHTRVQRQADVDHRRRKRKIEWMRKMYKDGMLHARETDQETSDLVDRAATGLVNTVDARGTEAVMEWEVDELLQWTTALN 376 Ciona intestinalis
NP_001019436 162 HFSKLKRKQDLEKKRKIKKIEWMRQMYYLGSLEAKVTDRETLVLIHKATKGLIKSIEDGGVDSVMEWEVDEVLNWTNTLN 241 Rattus norvegicus
Q569B9       162 HFSKLKRKQDLEKKRKIKKIEWMRQMYYLGSLEAKVTDRETLVLIHKATKGLIKSIEDGGVDSVMEWEVDEVLNWTNTLN 241 Norway rat
XP_007059758 160 HYSKLKRKQDIDQRRKRRKIEWMTKMYHARSLRVKTEDPTTTILIQRSAEGIVNAIEKGGTDNVMEWEVDELLQWTNALN 239 Chelonia mydas
XP_002934975 170 HHSKLQRRQDVEKRQKYRKIEWMKKMYYEGSLHAETSDPEIALLVQQATEGVIQTAEEHGANTVMDWEVDELLSWTNALS 249 Xenopus tropicalis
Q8NCR3       242 FDEYIASWKEIATSNSSANFKG 263 human
NP_083523    242 FDEYIASWRETATSNSSANLKD 263 Mus musculus
NP_689800    242 FDEYIASWKEIATSNSSANFKG 263 Homo sapiens
XP_007903826 365 FEEYLKGWKDIGRSNKSENFKG 386 Callorhinchus milii
XP_001381470 245 YEEYVNNWKSIATSNSSANLQG 266 Monodelphis domestica
XP_002126507 377 FDDYLEVWKEAATSNVSEKTTS 398 Ciona intestinalis
NP_001019436 242 FDDYIASWRETATSNSSAYLKD 263 Rattus norvegicus
Q569B9       242 FDDYIASWRETATSNSSAYLKD 263 Norway rat
XP_007059758 240 FEEYISQWKEIATSNSSANYQG 261 Chelonia mydas
XP_002934975 250 YEEYISTWKEIGTSKSSCAFKG 271 Xenopus tropicalis
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