pfam14942: Muted (this model, PSSM-Id:405610 is obsolete and has been replaced by 464390)
Organelle biogenesis, Muted-like protein
The protein is a coiled-coil protein and belongs to a family found in eukaryotes. It undergoes alternative splicing forming two isoforms. The larger isoform is 187 amino acids long in protein sequence length and 21 kDa in mass. The smaller isoform is 110 amino acids long in protein sequence length and 12 kDa in mass. This protein associates with other proteins in order to form biogenesis of lysosome-related organelles complex-1 BLOC1 complex. BLOC-1 is required for the normal biogenesis of specialized organelles of the endosomal-lysosomal system.
Jiyao W et al.(2023). "The conserved domain database in 2023.",