5T5W


Conserved Protein Domain Family
IL28A

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pfam15177: IL28A 
Interleukin-28A
The protein family, Interleukin-28A, plays an important role in modulating the immune system. This protein family is induced by viral infection and interacts with a class II receptor. This family of proteins is found in eukaryotes. Proteins in this family are typically between 145 and 195 amino acids in length.
Statistics
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PSSM-Id: 464546
Aligned: 22 rows
Threshold Bit Score: 144.401
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5T5W_C         3 ARGCHIAQFKSLSPRELQAFKRAKDAL-EESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLDATADTd 81  human
K9M1U5        24 PRRCLLSHYRSLEPRTLAAAKALRDRYeEEALSWGQRNCS---FRPRRDPPRPSSCARLRHVARGIADAQAVLSGLHRS- 99  human
ANQ43304      23 RRHCHMSRYRSVSPSDIRAVRRLHNEH-EKSPFSDGIKCYRKMLRQKPSVCDLQASDRLILTLERVTLAVDVLTNMTES- 100
B4ER10        28 KKSCSLSKYQFPAPLELKAVWRMKEQF-EDIMLLTNRKCNTRLFHRKWDIAELSVPDRITLVEAELDLTITVLTNPTTQ- 105 chicken
XP_003467209  32 TKECHMAKFKSLSPQELQAFKTAKDAF-EEQLLLKDSRCSLRLFPRTWDLGQLQVWERPLALQAELALTLKVLGTVTDP- 109
XP_021589699  38 ARDCDMAQFKTLAPQELQAFRKARDAF-EDSHLPKDHNCPSPLFPRPWDLRQLQVWERPVALQAELALTLRVLGTMANS- 115
EGV93039      30 AKDCHIARFKSLSPQEREAFLKATDAI-EKWLLNKDVRCSSRLFPKAWDLKLLQVQERLKALQAELHLTLQVLENVTDS- 107
ELW72398      31 GRSCNMSRFKSLSPRELEAFKKAKDAL-EKSLSLKKYSCKFRLFPRDWHPRHLQMWERLMALEAELALTLRVLGSVADS- 108
NP_001297721  28 KKSCRLSQYGSPAYSELAEVLKFKKYY-ENIT-SKDPKCSTRLFNRKWTPNELSVPDRLLLVEAELDLTIAVLAHPTVD- 104 mallard
XP_012402700  23 ERSCQISQFKSLSPRELETFKVAKDAY-EKAMLQTERKCSSRFFHRNWDLRQLPVSVRPVVLQAELKLTLEVLKAVTKP- 100 Tasmanian devil
5T5W_C        82 pALGDVLDQPLHTLHHILSQLRACIQPQPTAGPR--TRG----RLHRWLHRLQEAPKKESPGCLEASVTFNLFRLLaRDL 155 human
K9M1U5       100 -ELLPGAGPILELLAAAGRDVAACLELARPGSSRkvPGA----QKRR-----HKPRRADSPRCRKASVVFNLLRLLtWEL 169 human
ANQ43304     101 -PLAKLLSLPLTMLLSLEDDLKICRKSPLYSDP---PSE----QLMPWLHHLKHFREKVSSECVQDAVLLSLTQLLiEDI 172
B4ER10       106 -RLAETCQQPLAFLTQVQEDLRDCLALE---APShqPSG----KLRHWLQKLKTAKKKETAGCLEASAILHIFQVL-NDL 176 chicken
XP_003467209 110 -ALGDVLEQPLHMLRHIHAQLQACVPTLRTAAPR--PVSr---RLSHWLQRLNQASKKASPGCLQESVTFNLLRLLtRDL 183
XP_021589699 116 -TLGDVLDQPLHTLGHIQSQLQACAPAQPTAGPR--PQGrhrhRLSHWLQRLQQAPEKESPACLQASVTFNLLRLLvRDL 192
EGV93039     108 -ALYPILEQPLHTLSNIHSQLQACIQPEPAAEPR--PPSh---RLSRWLHRLREAQEKETPGCLEISVTSNLFRMLlRDL 181
ELW72398     109 -ALGDVLDQPLHVLRHIHSLLQACVPAQ--------PQG----HLPSWLLQLQEVEKKKSPGCLKAAATFNLFRLLnQNL 175
NP_001297721 105 -KLAEKSQQPLAFFTQAREDLRGCVAAEAPSHQ---PSG----KLRHWLQKLETAKKTETASCLEYSTIVHLFQVL-HDL 175 mallard
XP_012402700 101 -ELDSVLAQPLQTLSHIHQEIQscvtsqtskEHK--LPG----RLKNWLNKLSEA-RKEPQNCLEASIMLNLFRLLtQDL 172 Tasmanian devil
5T5W_C       156 NCVASG 161 human
K9M1U5       170 RLAAHS 175 human
ANQ43304     173 MCWANN 178
B4ER10       177 RCAAQR 182 chicken
XP_003467209 184 RCVARP 189
XP_021589699 193 KCVASG 198
EGV93039     182 PCVARG 187
ELW72398     176 KCVASE 181
NP_001297721 176 GCVAIP 181 mallard
XP_012402700 173 RCVAYG 178 Tasmanian devil
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