19075852 89 GRTYTQISDISAKNDG----QTVLLRARVYTSRLQGNkMCFFSLRQKYDT--IQALAVVNKDt-iSKQMVKwCGSISLES 161 fission yeast 20139911 1 --MKMLVKQIY-ENAKeldkSKIKIKGWVVTSRGNKk-IQFIELNDGSSVlhLQLVLKS-EKm-dLNDIH-----FKTGS 69 Mycoplasma pulmonis 14520464 -------------------------------------------------------------------------------- Pyrococcus abyssi 18313428 -------------------------------------------------------------------------------- Pyrobaculum aerophilum 14590195 -------------------------------------------------------------------------------- Pyrococcus horikoshii 19111871 4 FQLPKTLKSLWHHPHNg---ELISINGWVRSIRKLKN-VCFAMVSDGTCQqaLQVVTS--------PEQSK---KLSYGA 68 fission yeast 13541490 -------------------------------------------------------------------------------- Thermoplasma volcanium 16082537 -------------------------------------------------------------------------------- Thermoplasma acidop... 20139951 1 --MQLKIKEIFNQDYVklegQKIQIKAWVRSNRDSKk-IGFLVLNDGSSLtnLQAVYRV-DKidnYEEIAA----ARMWA 72 Ureaplasma parvum 135160 13 FYSSLTVKSLYEQVHHts-hDPISINGWIKSIRLLKR-IAFLDLQDGTSVnpLRIVIPLT-N----TDEVQfLKILKTGQ 85 baker's yeast
19075852 162 IVLVEGIVKKSPEiiksaTVQDAEIHISS----IYVISPIkKNlPFLVEDAGRSeeqireseenaaegdskfvrvNLDTR 237 fission yeast 20139911 70 SIKAEGILNYTPK-----AEQSVELIVDK----ISLLAQS-DEd-FPIQTKKTT----------------------LEFL 116 Mycoplasma pulmonis 14520464 -------------------------------------------------------------------------------- Pyrococcus abyssi 18313428 1 ---------------------------------MPIHPSVtELeKLVIDKESYKr--------------------MLEEW 27 Pyrobaculum aerophilum 14590195 -------------------------------------------------------------------------------- Pyrococcus horikoshii 19111871 69 SVNIEGQLAVSKNak--lGLQQYELLAEK----IKIYGQInDD-NYPIQKKHLT----------------------TEML 119 fission yeast 13541490 1 -----------------------------------------------------------------------meakEISDL 9 Thermoplasma volcanium 16082537 1 -----------------------------------------------------------------------mesgEINTL 9 Thermoplasma acidop... 20139951 73 AVVIEGVIKLTPT-----AKQPLELEVLN----AQILKQS-DEd-FLLSNNDLN----------------------LETL 119 Ureaplasma parvum 135160 86 TLSISNATWQSTPn----RKQPFELQIKNpvksIKLVGPVsEN--YPLQKKYQT----------------------LRYL 137 baker's yeast
19075852 238 LDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNEIHTPKMSGASSEGGS--NVFKIQYFKTD-------------- 301 fission yeast 20139911 117 RTIPHLRHRSNTIKAVMLVRSSISFFIHEYFQKNDFSLVAAPIITSNDGEGAG--ETFIVDSEdkepff---------gn 185 Mycoplasma pulmonis 14520464 1 -MNAVEIISR-DIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWP--DPAGEGIRPAevdv----------y 66 Pyrococcus abyssi 18313428 28 LKYSWRWAVNEKYKLVFKVQASILRALREFLDSKGFVEVLSPIIGPVTDPGIRgaKQASIDFYGAE-------------- 93 Pyrobaculum aerophilum 14590195 1 -MSVIKIISR-DIYKVIDIQTRILDYMTKYFLGKGFKWLLPVMLSPITDPLWP--DPAEEGVKPLevev----------y 66 Pyrococcus horikoshii 19111871 120 RQIPHLRLRTAKQGEIFRLRSDSLKALRQFFSSKDFTETNPPIITSSDCEGAG--EVFTLTPQETHknksferddqkhff 197 fission yeast 13541490 10 VYEVNSHLEKPELQRALKIESSVRSYLSDYLKGRGFIEVPPVIISVLTDPLN---HPVYD---Ptidy-----------y 72 Thermoplasma volcanium 16082537 10 IEEISEHLEKPELYHALKVQSSIRSITSEFLKERGFIEVPPVIISVLTDPLN---HPVFD---Ptidy-----------y 72 Thermoplasma acidop... 20139951 120 RLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSWLAAPLFTGNDAEGAG--ETFSIQKFdneef-----------f 186 Ureaplasma parvum 135160 138 RSLPTLKYRTAYLSAILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAG--ELFQVSTNTSPtassy--------f 207 baker's yeast
19075852 302 ---GFLSQSPQLYKQMLIAAdRERVFEIGPVFRAEDSNTYR---HMTEFTGLDLEMAFNEhYHEVMEFIEKLFLYIFKTI 375 fission yeast 20139911 186 nvkATLGVTGQLHAEAYALG-LQKVYTFAPTFRAENSNTKK---HAAEFWMVEPEVAFFT-LKELIQMSEEMLKYVIKKV 260 Mycoplasma pulmonis 14520464 67 gvrMRLTHSMILHKQLAIAMgLEKIFVLSPNIRLESRRKDDg-rHSYEFTQLDFEIEGAK-MKDVMRLIEELIYGLFRKA 144 Pyrococcus abyssi 18313428 94 ---YKVMSSAILYKQYMARV-LGKIYFVSPNIRLEPPDSIFtgrHLVEFYQLDLEMYKAT-YHEAMDLAEDLITYVVKYV 168 Pyrobaculum aerophilum 14590195 67 gkkMRLTHSMILHKQLAIAMgLKKIFVLSPNIRIETRERDDg-kHAYEFTQFDFEVEGAK-MKDIISLVEELMHGLFRKA 144 Pyrococcus horikoshii 19111871 198 drpAFLTVSTQLHLEALALG-LSRVYTISPAFRAEQSHTSR---HLAEFWMLEAEVAFMTsLSQLTSLMEDMIKYTLNSL 273 fission yeast 13541490 73 gykYSITKSMIFHKHILTKH-FGKIFTFSPNIRLEEEDKAEtgrHLSEFTQLDLEIRDAT-REDVMSLGEEMIVELFSKI 150 Thermoplasma volcanium 16082537 73 gykYSLTKSMIFHKHLLTKH-FDRIFTFSPNIRLEEEDKVKtgrHLAEFTQLDLEMKGAS-RDEVMSLGEDMIIDLFKKI 150 Thermoplasma acidop... 20139951 187 gkqTHLSVTGQLQAEAYAQA-FGNVYTFGPTFRAEKSHTNR---HLAEFWMIEPEMAFVD-LKGMQDIVEDLVKHVIKAV 261 Ureaplasma parvum 135160 208 gkpTYLTVSTQLHLEILALS-LSRCWTLSPCFRAEKSDTPR---HLSEFWMLEVEMCFVNsVNELTSFVETTIKHIIKAC 283 baker's yeast
19075852 376 REKYAKQV--AVVRQqyPSEDFILP----------------DADRIRFHFKDAVKLLK-----EAGYRKqlvpgqkvped 432 fission yeast 20139911 261 LEKRRDEL--VFLDThiKPGLIQSled-----------fleSN-LEIIEYRKVIEILEk---nKVFFEEq---------- 313 Mycoplasma pulmonis 14520464 145 -----E----EWTG-----REFPR-----------------ARHFKVYDYKDILEEFG---------------------- 171 Pyrococcus abyssi 18313428 169 KDVHGKELe-AVLGR--QLYEFKR-------------------PFKRYSHKEAVEFVN-----KLGCE------------ 209 Pyrobaculum aerophilum 14590195 145 -----E----EWTG-----RDFPK-----------------ARHFKVYEYKDILDEFG---------------------- 171 Pyrococcus horikoshii 19111871 274 MEQNYHR---DHWD-----QLLKP--------------------WKCMTYSEAIEELSa---vKKTWKYp---------- 312 fission yeast 13541490 151 KKTHSDDL--KFFG-----RDLRIP----------------KKPFERIRYKDAEKEYG---------------------- 185 Thermoplasma volcanium 16082537 151 KRSNEEDL--KFFG-----RDLRIP----------------SKPFKRIAYLDAYKQYG---------------------- 185 Thermoplasma acidop... 20139951 262 LEKNQQEL--EFLAQrnDENLIKKlqk-----------vveSK-FERIEYKDAVKILAdavknGHQFENn---------- 317 Ureaplasma parvum 135160 284 IDNQQELLpkQFISSqeNNASSELSinqetqqiktrwedliNEKWHNITYTNAIEILK-----KRHNEVshf-------- 350 baker's yeast
19075852 433 eefhyceDPEFDDFSTPEERALGqivrEKYHTDFYVIDKYPSSVRPFYTMPDPEDPRYSNSYDFFMKG--QEIMSGAQRI 510 fission yeast 20139911 314 ------nIEFGMDLKTEHERFIA----EKYAKGPVGVINYPKKLKAFYMYQNDDN-ETVAAFDLLVPGi-GELVGGSQRE 381 Mycoplasma pulmonis 14520464 172 ----------SDEK---ASMEME------E--P-FWIVNIP---REFYDREEN---GVWKNYDLILPYgyGEVSSGGERE 223 Pyrococcus abyssi 18313428 210 -------NSPREELRWECEKVMS----AHHDSP-FFVYDYPRGSRGFYDREDPERPGVLRDFDMLYPEgfGEAISGAERE 277 Pyrobaculum aerophilum 14590195 172 ----------SDEK---ASQVME------E--P-FWVINIP---REFYDREED---GVWRNYDLILPYgyGEVLSGGERE 223 Pyrococcus horikoshii 19111871 313 -------PKWGNDLSSEHEKYLC----EILHKTPVFVTDYPQKIKPFYMKSSGPD--TVAAVDLLVPQv-GELAGGSLRK 378 fission yeast 13541490 186 ----------GDFE-SILSKEKK------E--P-FWIIDIPLEKREFYDREDPQRPGILVDMDLVYPEgfGEALSGGERE 245 Thermoplasma volcanium 16082537 186 ----------EDFE-HILSSEMK------E--P-FWIIDIPLEKREFYDREDPSRPGILVDMDLIYPEgfGEALSGGERE 245 Thermoplasma acidop... 20139951 318 ------eIFFGMDLGSEHERYMC----ETYHQGPVFLQNYPKDIKAFYMKLNDDQ-QTVASTDLLIPGv-GELVGGSQRE 385 Ureaplasma parvum 135160 351 ----kyePKWGQPLQTEHEKFLAg----EYFKSPVFVTDYPRLCKPFYMKQNSTPDDTVGCFDLLVPGm-GEIIGGSLRE 421 baker's yeast
19075852 511 HDPELLVERMKALGVSPdVGLQQYIDAFAIG-CPPHAGGGIGLERVVMFYLNLP-NIRLASSFPRDPKRLLP 580 fission yeast 20139911 382 NRYEKLEQRIQELNIDQ-KDIQWYLDLRKYG-YSGSAGFGLGLERLVMYITGID-NIRDSIPFPRTPNNLKM 450 Mycoplasma pulmonis 14520464 224 WEYEKIVAKIRAAGLKE-DSFRPYLEIARAGkLKPSAGAGIGVERLVRFIVGAK-HIAEVQPFPRVPGIPAV 293 Pyrococcus abyssi 18313428 278 FEPERLVERIREGGEDP-AKYQWFLQMAKELyPLQTAGFGIGVERLTRYICGLR-AVWEARPYPKVAGIIGG 347 Pyrobaculum aerophilum 14590195 224 WEYQKIIEKIRASGLSE-ESFKPYLEIARAGkLKPSAGAGIGVERLVRFIVSAH-HVSEVQLFPRIPGIPAM 293 Pyrococcus horikoshii 19111871 379 DHLD-------EYKTYP-PELQWYLDLMKYS-NAPHGGFGLGIERLIAFLEGENtNVKETIPFPRSVGSIFA 441 fission yeast 13541490 246 YKLDRIIERIHKKRQTE-EQFKWYIEFAKDG-LYPSAGFGIGIERLTRYICGLS-RIEDVHPFPKVPGKLSL 314 Thermoplasma volcanium 16082537 246 YELSRIIDRIHRKGQTE-EQFKWYIEFAKEG-LMPSAGFGIGIERLTRFICGLE-RIEDAHPFPKIPGHLSL 314 Thermoplasma acidophilum 20139951 386 DSYEKLLKRCQELKMPI-ESLQWYLDLRRFG-YYMSSGFGIGFERLVMYVTGVN-NIKDTIPFPRSHGQIEF 454 Ureaplasma parvum 135160 422 DDYDKLCREMKARGMNRsGELDWYVSLRKEG-SAPHGGFGLGFERFISYLYGNH-NIKDAIPFYRTSAESID 491 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",