6URV


Conserved Protein Domain Family
Peptidase_S7
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pfam00949: Peptidase_S7 
Peptidase S7, Flavivirus NS3 serine protease
The viral genome is a positive strand RNA that encodes a single polyprotein precursor. Processing of the polyprotein precursor into mature proteins is carried out by the host signal peptidase and by NS3 serine protease, which requires NS2B (pfam01002) as a cofactor.
Links
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Statistics
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PSSM-Id: 395758
Aligned: 8 rows
Threshold Bit Score: 100.207
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6URV_B   15 LEDGIYGIFQSTFL-GASQ-------RGVGVAQGGVFHTMWHVTRGAFLVR---NGKKLVPSWASv---KEDLVAYGGSW 80  
P75194  156 LGYPFLRNKAASLFlNQTEqrkehmdKTTQILHEKPFVVLTDPAKPTLIRNk--GANFTGNTWTS----NYDLSKKSGLY 229  Mycoplasma pneumoni...
P33276  337 TTPQYTKFSVPSLS--RRQ-------IPITSDSRGSPGWTINALNPTELDG---QKIASSTSLSStggiRAGIYNADIAR 404  Mycoplasma gallisep...
Q50338   16 WTKTEQRFNHDDFY-GSMP-------TLTKNLRQG------QPVAGSKVHT---DYSNGFLNEYSl---NQGIVDFGTFK 75   Mycoplasma pneumoni...
Q50336  173 CKQGAER-FSYGYFySNMA-------RLTKNLRQG------DPNAGSKTHI---EYSNELLDKDSm---DQGIVRFSTFL 232  Mycoplasma pneumoni...
P75203  199 SNIAALNLNQTEVKpTRPE--------DVAQVTFKEPWSVDHHREIPTLTTnqlTTIKTKHFSGSk---LSWPFDHTKSF 267  Mycoplasma pneumoni...
P17763 1493 LDDGIYRILQRGLL-GRSQ-------VGVGVFQEGVFHTMWHVTRGAVLMY---QGKRLEPSWASv---KKDLISYGGGW 1558 Dengue virus 1 Naur...
P03314 1504 LEDGIYGIFQSTFL-GASQ-------RGVGVAQGGVFHTMWHVTRGAFLVR---NGKKLIPSWASv---KEDLVAYGGSW 1569 Yellow fever virus 17D

6URV_B   81 KldgRWDGeEEVQLIaaapgknvvnvqtkpslfkvknGGEIGAVALDYPSGTSGSPIVNRNGEVIGLYGNGILVGdn--- 157 
P75194  230 H---KFLG-KKYQIY----------------------GKSIVISDLNLSSGSSGSLLLNDRKQIVGIYFGVDGPK----- 278  Mycoplasma pneumoni...
P33276  405 NfqlVYRN-VKYKQY----------------------GYGYIIQNSNLSAGSSGSLALTSNNQALGIYFGTVSVDak--k 459  Mycoplasma gallisep...
Q50338   76 SaitDYHG-YEYKNH----------------------GYGLALTDTDLLGGSSGSLVFNQDKKISSIYSAATESD----- 127  Mycoplasma pneumoni...
Q50336  233 GaniNYHD-YDYRQQ----------------------GYGLTLTDTNLPGGSSGSLVFNQDKKISSIYSAATESD----- 284  Mycoplasma pneumoni...
P75203  268 KiknKWLG-QNYQMY----------------------GHGLGIDQVNLRKGTSSSLVINQKRQIVGIYFATVITNpkkav 324  Mycoplasma pneumoni...
P17763 1559 RfqgSWNAgEEVQVIavepgknpknvqtapgtfktpeG-EVGAIALDFKPGTSGSPIVNREGKIVGLYGNGVVTTsg--- 1634 Dengue virus 1 Naur...
P03314 1570 KlegRWDGeEEVQLIaavpgknvvnvqtkpslfkvrnGGEIGAVALDYPSGTSGSPIVNRNGEVIGLYGNGILVGdn--- 1646 Yellow fever virus 17D

6URV_B  158 sFVSAISQT 166 
P75194  279 -DELGFSQL 286  Mycoplasma pneumoniae M129
P33276  460 eATFGLVAS 468  Mycoplasma gallisepticum str. R(low)
Q50338  128 --SVGYAQL 134  Mycoplasma pneumoniae M129
Q50336  285 --SVGYAQL 291  Mycoplasma pneumoniae M129
P75203  325 rNDVGLVQM 333  Mycoplasma pneumoniae M129
P17763 1635 tYVSAIAQa 1643 Dengue virus 1 Nauru/West Pac/1974
P03314 1647 sFVSAISQT 1655 Yellow fever virus 17D
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