O43264         9 LAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYS--EF---LPSMQSAQGLITQVDKLSEDIDLLKSRIES-EVR 82  human
NP_956435      9 LASSGKLEKDDLACKISKLSRKVEETKEEVTDMINKKYI--EF---IPSMEGAEELLDQVESVSKDIDLLKSCIEN-EVQ 82  zebrafish
XP_001625466  20 LQKTGQLEQEDFNKCATKMLKKAEEVKAEVFNTIYKEYSyaGF---QDLSSSTSELNWKVSSLLKEIDATTKKVKG-SIL 95  starlet sea ane...
O48626        23 NDPTTPLSAPDLRLLINRLESHSLRIKSKVQSYLVAHHS--DF---SELFSLCQDTVSRTRLISDDVSDVLQLVSDrPID 97  thale cress
XP_002634365   1 --------MPSSEGSYRDLEKKLKDGLTSISADIVDKYG--NLkvaLNINNTAKLIFDRLENLEDTAEMSSRELSN-LIE 69  Caenorhabditis ...
O44218        14 FQSNGCASLEDTKSTVSKVQTRTERFQERVRKHIDENYS--EF---MTNHTSPDIFLEESSSLGREINDLLETVGT-EGL 87  Drosophila pseu...
KAE8592697     9 LANSGRLEKEDLGTKISRLSRRVEELKGEVCDMINKKYD--EF---LPSMQCAEDLVTQVHGLASDVDVLKSRIET-EVK 82  tropical clawed...
CAF97316       9 LASSGKLEKEDLSGKISKMSRKVEETKEELYEMINKRYA--DF---LPSLQSSEQLMIQVDEVSKEMEALKNCIKN-EVW 82  spotted green p...

O43264        83 RDLHVSTGEFTDLKQQLERDSVVLSLLKQL-QEFSTAIEEYNCALTEK-----KYVTGAQ-RLEEAQKCL------KLLK 149 human
NP_956435     83 QNLHDAVTEYAKLKQQLEKNTAVIDLLQHL-QEFDTAIEEYHRALQEK-----NYVVAAK-QHGTARACV------DALK 149 zebrafish
XP_001625466  96 PDLDAAAEEHANLVQQLKETDMVRVILIRL-GKIHLGLETLPGTLKSK-----AFCKAAK-LLEDVKE--------DLEH 160 starlet sea ane...
O48626        98 VEIRSVVDEITEKTKEVKLKRESLDLVNAI-VGICEALQETKEALKNG-----RFRFAAE-RIRELKVVLrigeeeDGEP 170 thale cress
XP_002634365  70 QTEKDSPEMLAEIKTQARSCENLVEFLQSM-KKVEEQLIIMRSKTTNRiewgnAILACKD-YLNETNLLL------EGIQ 141 Caenorhabditis ...
O44218        88 AALNGSSTQLADHSRELRELMLGLQVSEHI-LKIDELFQCVEEAKGTK-----DYLVVLD-LVGRLRSLIygegeaATQD 160 Drosophila pseu...
KAE8592697    83 SDLKVAVNEFTELKQQLEKNTVILGVLEQL-QEFDSAIEKYNCALAS------KNYISAArHLEKAHSCL------KVLK 149 tropical clawed...
CAF97316      83 LDLNPTTKD-----RQADRSANSLFYLTSLcLQFHNAMEEFDKALPNK-----DYVEAAN-MLERARTSV------DSLK 145 spotted green p...

O43264       150 SRKCFD-LKILKSLSMELTIQKQNILYHLGEEWQKLIVWK---FPPSK-DTSSLESYLQTELHLYTEQSHkeektpMPPI 224 human
NP_956435    150 TWKDTE-LPIVRALSSEITIQRENLIYHLGEEWQKLAVWK---LPSTKtELTGAKSFLKTALHLNKGGSKvdesvpHALL 225 zebrafish
XP_001625466 161 VPRAGQeGKIFIALREELRRLSIQLVNKLDTTWNNCLLWS---IPTSS-SLDSAHAHLKTQLKLCTYGSE---------I 227 starlet sea ane...
O48626       171 VA--------YALLRKEWSNCFDEIQEVLAKFMENAVRFE---LDSSR---------IRIKYQLSVGETA------GIAL 224 thale cress
XP_002634365 142 CEGFDMsIP-LKHFAAEYSVLSYNCRYQLSADYDRAMS-----VPKVSkKQGGDKSNVSVTVLNLSTPEE------QKNM 209 Caenorhabditis ...
O44218       161 VVRIFQaLECYETIKVKYHVQAHLLQQNMQERFDRLVQLNcksFPNSK----------CVTLLVSKEEGQ---------L 221 Drosophila pseu...
KAE8592697   150 SRKGCE-LKLLKSLGIELTVQKQNLLYHLGEEWQQLAVWK---LPPSK-ENSSVEMILKTELHLCTLPSNdes-ttGPLL 223 tropical clawed...
CAF97316     146 VWKLSQ-VPLLGALSSELTVQRENLIYHLGEEWKRLIIWK---LPPSNdp-aGPQSFLSVALNLSHACVEgpeakpSALL 220 spotted green p...

O43264       225 SSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHAV-IESQPN------IVIIRFESI-MTNLEYPSPSEVFTKI 296 human
NP_956435    226 SSILQALSIQGELHKKIKLFGQVLFKYILKPLILYPSLVVEvSSQPEQ------GAVLSLQCL-ETKAEHPDPSQVYTKV 298 zebrafish
XP_001625466 228 TEVINALAFLGRLEQKLKIFGKKLIQFIFRPLIIFPNLKVS-VEKDKE------DITISLVRD-TTKCKIVEPGKVYSKI 299 starlet sea ane...
O48626       225 STVLEAMEVIGILDYGLAKAADSIFKHVITPAVTHASTFAA-VEDLCKsagevtEATLRLEQSsDHKFEDVDGDAMYSGI 303 thale cress
XP_002634365 210 NETLTAMNMIGQLPERLDAWKTVILNVFCEAIVSSRDGVDVfFVDNPT------PAQTRFLINqKPRGKKDKPMDV-EKV 282 Caenorhabditis ...
O44218       222 HDIVIALF---QERYNPVRLCEFLLENCIEPLILKPVGVEC-NENAEAgtyvqlSLSYSTKESgTASGTSTQLRPNYKQV 297 Drosophila pseu...
KAE8592697   224 GSVLQAFAILGELNTKLKFFSQLLLNYILKPLVTYPSLHAQ-METQQQ------GVILRFESV-ETQLEHPPPSEVFIKL 295 tropical clawed...
CAF97316     221 CCVLQALAIQGELQNKIKLFSQALVKSMLKPLVVHPSLWVNvVEQQDE------GIVLAFESLqESSKERSTPSQVYSKL 294 spotted green p...

O43264       297 RLVLEVLQKQLLDLPLDTDlenektstvPLAEMLGDMIWEDLSECLIKNCLVYSIP---TNSSKLQQYEEIIQSTEEFEN 373 human
NP_956435    299 LTVLKTLHEHLFDVSVDEK---------KVSEILGGLIWEEMSECIIRECLVHSIP---ANSSQLAEYSEVIKQTEDFES 366 zebrafish
XP_001625466 300 IEVLEVLCTYFTPSQDNSGlp-----kiSILQYLGNFLWPALSEDLIKDCLAKSIP---NTSAQLEKYQEVISQTEKFEE 371 starlet sea ane...
O48626       304 LKVVKFICSSLCFGNV------------TWIHSFGRLTWPRISELIISKFLSKVVP---EDASKLADFQKIIERTSQFEA 368 thale cress
XP_002634365 283 LQSMDVFFSKLSDVLKSHEllda--cgkSFVAMIGHAIQPQLNEMILKDVVAIAAPvteTAEEDQEMFLRLLQFGEDFVE 360 Caenorhabditis ...
O44218       298 LEHFRLLLQTLSGINHSLSss------qHVFSIIGDHVKDRMMHLLVNDCLIPAVP---ETMEEYQA-STLCEDVAHFEQ 367 Drosophila pseu...
KAE8592697   296 RLVFELLHKHLLDVPVEDSpqagetgkvVLAEVLGEMIWEEISEAIIKDCLVYSIP---NNSSKLVQYDEVINATEEFEN 372 tropical clawed...
CAF97316     295 LMVLKTLHAHLL--DVSIGd-------kRLSTILGELIWEEMSGCIIHECLVHSIP---NNSSELEKYTTVIKQTEEFEK 362 spotted green p...

O43264       374 ALKEMRFLK--GDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVK----------IIPD----------SKI 431 human
NP_956435    367 SLKEMGYLA--GDSTELLKYARNVNCHFASKKCQDVIVAARKLMTSEMHNTVK----------ITPE----------YKL 424 zebrafish
XP_001625466 372 ELHQLEIVD--KLPSSLTKYAKDVGVHFGNKKCQDLLVTARDLMKDDIYNTVMvdrftdtallVTPQeiqeallgkkSKV 449 starlet sea ane...
O48626       369 ALKELNFVSssDAESRLSKYAEDVEVHFASRKKIEILAKARNLLLQCNF--------------TIPQ------------- 421 thale cress
XP_002634365 361 NMKTLGFFS--PDAKLL--FSLDTDTIFVTRRCFAIVSKANKLINETYDKLVT----------VGVDd--------tAVK 418 Caenorhabditis ...
O44218       368 YLADSFLINp-EVDRGLSQFIEQYGTYYRNRLCSRVLESTREIIQRDLQDMVL----------VAPN------------- 423 Drosophila pseu...
KAE8592697   373 ALKGMNYLK--GDATDLLKYARNVNAHFASKKCQDVIVIARNLMTSEIHNTVK----------ITPD----------SKI 430 tropical clawed...
CAF97316     363 ALKDMDFLQ--RDSTDLLKYARDINCHFASKKCKDVIVAARKLMTSKMHNTVK----------ITPD----------YKL 420 spotted green p...

O43264       432 NVPELPTPDEDNKLEVQKVSNTQYHeVMNl------------------------------EPENTLDQ-HSFSLPTCRIS 480 human
NP_956435    425 SIPKLLSPSGGEKERKESSKRSGHYdQQSl------------------------------ENEKQLSP-NTLCLPVCRIS 473 zebrafish
XP_001625466 450 KNPVNTVLKAINHNYLLVYNAHFFHaELIltwqplairlpssymeyywichqqeiseltkSDQEETLSeFTFNFPTCRIS 529 starlet sea ane...
O48626       422 ---------------------DIAM-----------------------------------RNAKHIVC-LLFSSERCVVS 444 thale cress
XP_002634365 419 DIDLLSKAHTHAELYAKEYGNDLAR-LWS-------------------------------HNEESQFP-SFFAFQKCTVS 465 Caenorhabditis ...
O44218       424 ------------------------------------------------------------NQAMDVTGcDPFLFPRCMVS 443 Drosophila pseu...
KAE8592697   431 TVPTLSKYEGSEK--IIKKENHLSQeAPGl------------------------------ENDVKLSQ-HTFALPTCRIS 477 tropical clawed...
CAF97316     421 RLPKLPAPGPEVKVKPEATREELTM-----------------------------------ENAKQLSA-LSLCLPACRIS 464 spotted green p...

O43264       481 ESVKKLMELAYQTLLEATTSSDQCA-VQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQF 559 human
NP_956435    474 ESVQQLMDLAIQTLSEAVGSSPQCG-VQLFYTVRNIFHLFYDVVPTYHKDNFLKLPHLAAIQHNNCMFIAHHLLTLGFQF 552 zebrafish
XP_001625466 530 ESTKKLMDLAYSTLIEATTSPFQTA-VQLFYTVRNVFELYCSVVPAYHQDNLATLPQLSALHHNNCMYISHLLMTAGHQF 608 starlet sea ane...
O48626       445 EAASQLMNLVHKTLEDVCVSSARVA-SEFYNAARDSILLYEAVVPVKLEKQLDGLNEAAVLLHNDCLYLFEEILGLAFEY 523 thale cress
XP_002634365 466 ASTISFVNLLRDNVKAAFACEDEGArAKLALTAENIVRLYVIQSPRKHAELFSSIPNMSAIFYNNCHYISHCIMTMSFEA 545 Caenorhabditis ...
O44218       444 RSAQDFMKLMERILRQPTEKPGEDEaDPLAGVIGMMLQTYIDEVPKVHKKLLESIPQQSVLFHNNCMYFTHWVAqnankg 523 Drosophila pseu...
KAE8592697   478 ESVQKLMELAYQTLSEATTSSKPCS-IQLFYTVRNIFHLFYDVVPTYHKENLQKLPQLSAIHHNNCMYIAHHLLTLGHQF 556 tropical clawed...
CAF97316     465 ESVQQLMELALHTLCEAVGSSAYCA-LHLFITVRNVFQLFYDVVPTYHKENLLKFPHLAAIQHNNCMYLAHHLLTLGHHF 543 spotted green p...

O43264       560 RLRLA 564 human
NP_956435    553 KPYLP 557 zebrafish
XP_001625466 609 SAQLP 613 starlet sea anemone
O48626       524 RASFP 528 thale cress
XP_002634365 546 SGENQ 550 Caenorhabditis briggsae
O44218       524 iesfp 528 Drosophila pseudoobscura pseudoobscura
KAE8592697   557 RYHLP 561 tropical clawed frog
CAF97316     544 KAHLP 548 spotted green pufferfish