3EVS,2HLQ,2L5S


Conserved Protein Domain Family
Activin_recp
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pfam01064: Activin_recp (this model, PSSM-Id:395845 is obsolete and has been replaced by 460048)
Activin types I and II receptor domain
This Pfam entry consists of both TGF-beta receptor types. This is an alignment of the hydrophilic cysteine-rich ligand-binding domains, Both receptor types, (type I and II) posses a 9 amino acid cysteine box, with the the consensus CCX{4-5}CN. The type I receptors also possess 7 extracellular residues preceding the cysteine box.
Links
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Statistics
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PSSM-Id: 395845
Aligned: 20 rows
Threshold Bit Score: 32.5408
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3EVS_C              27 ChHH------------------------CPEDsvNNICS-----------TD--GYCFTMIE--EDDSGMPVVTSGCLgl 67  
P80204              37 CtKD------------------------------NFTCE-----------TD--GLCFVSV---TETTDKVIHNSMCIae 70   Norway rat
FlyBase:CG8224-PA  131 CdT-------------------------CKES--NNICE-----------TD--GFCFTSVE--KNSDGSIIFSYSCMvv 168  fruit fly
O16623              81 CnSDkcnddsftipsdvvltippvikcfSQDLieDNYCFghyctyeqeyiRNdfGDAYTSIN---------SPSRGCSdl 151  Caenorha...
P70539              33 CdSS------------------------------NFTCQ-----------TE--GACWASV---MLTNGKEQVSKSCVsl 66   Norway rat
Q7QJY6              40 CaDT---------------------------AihAHYCQn-------------aIQCWKSRT--RDPEGNENVQRGCTte 77   Anophele...
AAB22240            60 LeKT--------------------------NQsgVESCEg---------eKDkrLHCYASWR--NNSGFIELVKKGCWl- 101  African ...
Q24468              44 CnTT------------------------QQCEtrIEHCKm---------eADkfPSCYVLWSvnETTGILRIKMKGCFt- 89   fruit fly
O35607              23 ttaasqnqerlcafkdpyqqdlgigesrISHEngTILCSk-------------gSTCYGLWE--KSKGDINLVKQGCWsh 87   house mouse
2HLQ_A              16 GeSR------------------------ISHEngTILCSk-------------gSTCYGLWE--KSKGDINLVKQGCWsh 56  

3EVS_C              68 -----egSDFQCRD---TPipH---------QR---RS-IECCtERNECNKDL 99  
P80204              71 idliprdRPFVCAP-------S---------SKt-gAV-TYCC-NQDHCNKIE 104  Norway rat
FlyBase:CG8224-PA  169 kynmqrsKPFECLT---SN--E---------RFd-tYR-IDCC-KSDFCNKNE 204  fruit fly
O16623             152 eyaedlnSPNMCRL---LN-----------------GL-LECQcSTPYCNRDQ 183  Caenorhabditis elegans
P70539              67 p---elnAQVFCH--------S---------SNn-vTK-TECC-FTDFCNNIT 96   Norway rat
Q7QJY6              78 h----eqLPLYCSQnqkPNtgDsggpkkrhvSSt-gMYnIECC-TGDYCNNGS 124  Anopheles gambiae str. PEST
AAB22240           102 -------DDFNCYDr-qECiaK---------EEn-pQV-FFCCcEGNYCNKKF 135  African clawed frog
Q24468              90 -------DMHECNQtecVTsaE---------PRq-gNI-HFCCcKGSRCNSNQ 124  fruit fly
O35607              88 igdpqecHYEECVV---TTtpP---------SIq-nGTyRFCCcSTDLCNVNF 127  house mouse
2HLQ_A              57 igdpqecHYEECVV---TTtpP---------SIqngTY-RFCCcSTDLCNVNF 96
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