4Q1U


Conserved Protein Domain Family
Arylesterase
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pfam01731: Arylesterase 
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Arylesterase
This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1.2. These enzymes hydrolyse organophosphorus esters such as paraoxon and are found in the liver and blood. They confer resistance to organophosphate toxicity. Human arylesterase (PON1) is associated with HDL and may protect against LDL oxidation.
Links
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Statistics
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PSSM-Id: 334656
Aligned: 7 rows
Threshold Bit Score: 127.579
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4Q1U_A 168 NDIVAVGPEHFYATNDHYFIDPYLQSWEMHLGLAWSFVTYYSPNDVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHV 247
P27169 168 NDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHV 247 human
Q90952 167 NDVVAVGPDSFYATNDHYFYDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADILDHNVHV 246 chicken
Q62087 167 NDIVVLGPEQFYATRDHYFTSYFLVLLEMILDPHWTSVVFYSPKEVKVVAQGFSSANGITVSLDQKFVYVADVTAKNIHI 246 house mouse
Q21427 172 TDISAAGLNSFFFVKSSIFGTNFALNIIERVVPIPTGYIYFVSGNNIQQISRVSFPTGIVYDSVKKSIFVTSSTRNSIYR 251 Caenorhabditis elegans
O01811 178 QDIAVVGPDRLFVTNMAAFGRGWAQILEFSLQTGQGAVYYYDGSKLSTAASSLIAPTGIGYDAKRRILYVGSMIRESIFA 257 Caenorhabditis elegans
Q15165 167 NDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHV 246 human

4Q1U_A 248 YEKHAN 253
P27169 248 YEKHAN 253 human
Q90952 247 MEKHAD 252 chicken
Q62087 247 MKKHDN 252 house mouse
Q21427 252 MKVQVK 257 Caenorhabditis elegans
O01811 258 YKVAKD 263 Caenorhabditis elegans
Q15165 247 LEKHTN 252 human
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