Conserved Protein Domain Family
Yip1

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pfam04893: Yip1 
Yip1 domain
The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.
Statistics
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PSSM-Id: 461468
Aligned: 213 rows
Threshold Bit Score: 29.3268
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012659681  13 SGLL-DRS----RA-GF--RWLKp--dKQALTVGVVVfvtlattLGIVALGAAFDATIDREVTVdnpdyppestcetfge 82  Halorubrum lacu...
Q6ICZ9        46 RSIL--NP----FR-IN--QTVHk---DSDLSGPIFLyla--lcLFQLL----------AGKIQ---------------- 85  thale cress
O94348        76 THVL--NP----FK-HV--DVHIm--dDTDMAGPILFc-----lLFSTF------------------------------- 108 Schizosaccharom...
Q6BHA2        99 LAVL--NP----MN-RNitSDIMa---DSDLAGPIIF-------VLLFGTLLLLAGKVQFGYIY---------------- 145 Debaryomyces ha...
Q9VK46       114 LAVL--NPl---RG-TD--QQILq---DTDMAGPLVF-------CLTLGGFLLLSGKVTFSYIY---------------- 159 fruit fly
XP_518011    108 LTVL--HP----LK-VA--DGSIm--nETDLAGPMVF-------CLAFGATLLLAGKIQFGYVY---------------- 153
XP_002637203 109 IAVL--NP-------TG--SATVeviaDQDLAGPLVFcl---lfGAALL----LHGKLSFGFIY---------------- 154
Q6CA93        82 LTVL--NP----FR-AI--SKHIm--dDSDLAGPILF-------CLLFGTFLLLSGKVHFGYIY---------------- 127 Yarrowia lipoly...
Q6FQ69        86 MYVL--RPtmssAM-LS--HEILn---DSDLAGPVIFf-----mLFGLF------------------------------- 121 [Candida] glabrata
Q5M7T4        95 RCVLmPMP----SLgFN--RQVVr--dNPDFWGPLAV-------VLFFSMISLYGQFRVVSWII---------------- 143 Norway rat
WP_012659681  83 dgdsvfveqcdrperidvdvgeeLRSASGEYvgyaLIGVPIWWAIFAL-ALHGGa-RLAGGS-------GS--LG--DS- 148 Halorubrum lacu...
Q6ICZ9        86 -----------------------------------FGVILGWVVVSSI-FLYIVf-NMLAGRn------GN--LNlhTC- 119 thale cress
O94348       109 -----------------------LSLHGRSH----FGYIYGIALLGSL-SLHFVl-RLMSAK-------NL--FFt-RT- 148 Schizosaccharom...
Q6BHA2       146 ----------------------------------------GVGLFGIIsLHYLF--KLMSDD-------VTidLI--RS- 173 Debaryomyces ha...
Q9VK46       160 ----------------------------------------GIGVMGCI-FFYCLlsLMV-SR-------SQvtFG---Av 187 fruit fly
XP_518011    154 -----------------------GISAIGCL---------GMFCLLNL-MSMTG---------------VS--FG---Cv 180
XP_002637203 155 --------------------------GVGGL---------GCVGIYAL-MNLMA-----TDE-------KNisFT---Ct 183
Q6CA93       128 ----------------------------------------GVALVGSVsLHWIL--KLMASD-------VSidFT--RT- 155 Yarrowia lipoly...
Q6FQ69       122 -----------------------LLMAGKVH----FGYIYGVALFGTI-SLHTLs-KQMATSssqqqqpSSlhFF--NT- 169 [Candida] glabrata
Q5M7T4       144 ----------------------------------------TIWIFGSL-TIFLLa-RVLGGE-------VA--YG--QV- 169 Norway rat
WP_012659681 149 FAIAAWAIaaeVARLV-AGLgaiwyvlatttvegttmesiateIVAAi--sTMQGPLlvasavviSVQWVVVVGGLEAYH 225 Halorubrum lacu...
Q6ICZ9       120 TSLVGYSL---LPVVI-LSAvslfv-------------pqgagPVRF-----VLGAAfv-----lWATRACSNLVVSLAD 172 thale cress
O94348       149 VSVLGYSL---LPLVV-IAFfkn-----------------iftFNGIa--gYALAALac-----iWCTYAASAMFVGILQ 200 Schizosaccharom...
Q6BHA2       174 ASVIGYCL---LPLVI-VSVigvfvs-----------ldnllgYIFS-----AFAVF--------WCTYSASGFFVAVLK 225 Debaryomyces ha...
Q9VK46       188 ASVLGYCL---LPMVVlSGIniliti------------qgtlgLIVS-----GISIF--------WCAISASKLFATAFS 239 fruit fly
XP_518011    181 ASVLGYCL---LPMIL-LSS-----------------------FAVIfslqGMVGIIltag-iigWCSFSASKIFISALA 232
XP_002637203 184 ASVLGYCL---LPMAL-LSIvtavls-----------fkgivgYLIS-----SLAVL--------WCSSASSKLFVIALS 235
Q6CA93       156 ASVLGYCL---LPLVViSGLgvvm---------------kldgTLGA-----ILSLVsv-----tWCTWSSSAIFVSVLR 207 Yarrowia lipoly...
Q6FQ69       170 ASILGYCF---LPLCF-LSFigvfh--------------sldnRIGH-----LTGALfv-----iWSTWSSSGFLNNLLQ 221 [Candida] glabrata
Q5M7T4       170 LGVIGYSL---LPLIViapil-----------------lvvgsFEMVstliKLFGVF--------WAAYSAASLLVGE-- 219 Norway rat
WP_012659681 226 DLDRG-IAGTVAGVLAVFGLLLAAV 249 Halorubrum lacusprofundi
Q6ICZ9       173 GGEEH--RGLISYACFLIYTLFSLL 195 thale cress
O94348       201 VNNMR---FLVAYPIALFYGVFAVI 222 Schizosaccharomyces pombe 972h-
Q6BHA2       226 LHNVRpLIAYPLAM---FYTVFALM 247 Debaryomyces hansenii
Q9VK46       240 MDHQQlLIAYPCAV---LYGGFALI 261 fruit fly
XP_518011    233 MEGQQlLVAYPCAL---LYGVFALI 254
XP_002637203 236 MDHQR------------LLMSLKIE 248
Q6CA93       208 LSDMRaLVAYPLAL---FYGVFSIM 229 Yarrowia lipolytica
Q6FQ69       222 LQNAR---TLIAYPLLIFYSVFALM 243 [Candida] glabrata
Q5M7T4       220 --EFKtKKPLLIYPIFLLYIYFLSL 242 Norway rat
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