Conserved Protein Domain Family
type_III_yscD

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TIGR02500: type_III_yscD 
type III secretion apparatus protein, YscD/HrpQ family
This family represents a conserved protein of bacterial type III secretion systems. Gene symbols are variable from species to species. Members are designated YscD in Yersinia, HrpQ in Pseudomonas syringae, and EscD in enteropathogenic Escherichia coli. In the Chlamydiae, this model describes the C-terminal 400 residues of a longer protein. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Statistics
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PSSM-Id: 274166
Aligned: 12 rows
Threshold Bit Score: 214.613
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAS94349   7 IILRVFSGPHTGAEVVLPPGD-HVIG-TEDSCDIILSDGGLAprhvSIGVTAgvpgapstvhitpldgpvryddaevpaT 84  Desulfovibrio vulga...
CAH19553   5 FKLRLLNGDLNGRELILPEGE-FTLGeQGCDVLLPLSDGNIV----TLCVNE---------------------------Y 52  Yersinia pseudotube...
AAQ60266   5 FKLKWLNGPLAGRELELPAGE-LRLGgDDPDIALALEEGAAT----VLTVTP---------------------------E 52  Chromobacterium vio...
AAB06000   2 HELRVLTGLHRGAALPLSGQQ-WWIG-AAQDADLALFDPGIK----DRHCRL---------------------------S 48  Erwinia amylovora
AAS20438   2 FELRVLNGQHQGAALPLVGEQ-WSIG-SAAQHDLALDDAGVE----SLHCRL---------------------------Q 48  Pseudomonas syringa...
AAL20319  12 WKIRFLGHVLQGREVWLNEGN-LSLGeKGCDICIPLAINEKI----ILREQA---------------------------D 59  Salmonella enterica...
Q01245     3 WVCRFYQGKHRGVEVELPHGR-CVFGsDPLQSDIVLSDSEIApvhlVLMVDE---------------------------E 54  Yersinia enterocoli...
BAC59958   4 WKIRILSGVHSGVEVTLPEGA-LVLGsDDFIADLVLSDAGVEanhfTLVCDS---------------------------E 55  Vibrio parahaemolyt...
AAC38402   5 YKIKLLNGAMRNRELQLPMGN-LTLGtEDNDIVYFPLEQVLNq--fLLDIRE---------------------------E 54  Escherichia coli
CAE42537   5 LEFRVLSGAQCMARCPAVHG--ARVG-ANPHCDIVLTGEDMPevagWLEIDQ---------------------------S 54  Bordetella pertussi...
AAR25803  29 WNLCFLSGPMYGRTMSLARGA-NWVG-TAADCEVILPDREIGakqvCLQVGA---------------------------L 79  Burkholderia multiv...
CAF24115 161 WLLKVIGGPNNGAEFYMQAGHsYILGtDPHTCDIVFHDTSVSrqhaKIAVSLedtlti---------------edlksrN 225 Candidatus Protochl...
AAS94349  85 GVTLAPATPchigetclawntpgapwetfdltprqsvtaADAAAgtSAMAGGDPAASTLSANAAASASPSGAAGDAPSGA 164 Desulfovibrio vulga...
CAH19553  53 QVMIQVAEE------------------------------VWING--AQHDLHTPLPLLQSIEIAGLVFVLGEQTDILSGI 100 Yersinia pseudotube...
AAQ60266  53 GVTMAPPVP------------------------------VWVEG--LPWDAGQALPLGQAIDLAGQGLVLAEADAALAML 100 Chromobacterium vio...
AAB06000  49 KTDLGWEVT------------------------------ALEGP--LNDNEGQRCEQLTDLQPG-TAFALGH-------- 87  Erwinia amylovora
AAS20438  49 RLDDSWTLN------------------------------AEEGA--VCDEEGN-ARPGIDLTLN-TAFLLGS-------- 86  Pseudomonas syringa...
AAL20319  60 SLFVDAGKAr-----------------------------VRVNG--RRFNPNKPLPSSGVLQVAGVAIAFGKQDCELADY 108 Salmonella enterica...
Q01245    55 GIRLTDSAEp-----------------------------LLQEG--LPVPLGTLLRAGTCLEVGFLLWTFVAVGQPLPET 103 Yersinia enterocoli...
BAC59958  56 SVMLRGCQDv-----------------------------TINGEnrAVGESGIELERHAVISVGVVKFALGYVEDELIVT 106 Vibrio parahaemolyt...
AAC38402  55 GVFLLSPVE------------------------------FWIDGqpTPYEADKPLPVGKIIDIAGCCFIIGDIDHSLPLS 104 Escherichia coli
CAE42537  55 GWRLAGAVTpgldaq------------------apcppaAFNEPveLGAAWITVAAPSAPWPAPPEPCGPDGSDTALHDV 116 Bordetella pertussi...
AAR25803  80 AVTVQN---------------------------------HGGESgaPVLLNDEPLGSGRRSLTPQDVVTVSS-------- 118 Burkholderia multiv...
CAF24115 226 GVLVSGSPLeikqnls-----------------psvivtLGTTSfvVYDREGEMQTIISPLLPSIVKVLQNEEEVAKPKE 288 Candidatus Protochl...
AAS94349 165 SQTPTLSATPANEVDDLVLgsptrPHHEkrWRSALLAAAVMLLCTSTVVITleTRPPAPPEraahlaAQLHAAGLTALRV 244 Desulfovibrio vulga...
CAH19553 101 KVTHRARFPLLVWLAIAIC-----VPLS--LLFVFLFWLTTQPETLRASIP--ADVPTQLA------ERLREPALQGIKG 165 Yersinia pseudotube...
AAQ60266 101 TLPSRRLPEVATTKPAARS-----WRLAggIVLICAALATAVLLWPKPVEPplFDARAWLA------REMADPGLSGVKA 169 Chromobacterium vio...
AAB06000  88 ---------------------------------IWLSIVSASMPWP---------EENDEP------MQEEEIPLAGAAA 119 Erwinia amylovora
AAS20438  87 ---------------------------------VWLCVSPAGDEWPSVPAVipKQPQADPE------PVRNDVPLKKVKS 127 Pseudomonas syringa...
AAL20319 109 QIPVSRSGYWWLAG-----------------VFLIFIGGMGVLLSISGQPEtvNDLPLRVK------FLLDKSNIHYVRA 165 Salmonella enterica...
Q01245   104 LQVPTQRKEPTDRLPRSRLgv--gLGVLslLLLLTFLGMLGHGLWREYNQDgqLVEQEVRR------LLATAAYKDVVLT 175 Yersinia enterocoli...
BAC59958 107 NVTDAQTKQDAPVVTAQSTsw--kRTALiaVLCSAIPSAIFAGMWYSQANGndSEVVAEAEpivlvrNILNELGLNDVRV 184 Vibrio parahaemolyt...
AAC38402 105 DVPERFSAKNQRKKRLILAsv--------iGATFALSGAIGSYVLLSPKAEppTFTRADVY------QQLKENKLHAITL 170 Escherichia coli
CAE42537 117 PGSTSPPSVAALMPRRRAGrp--wLALGaaAAVLLVGLATALVSVTTPATPpaAPPPTPTAplvraaALIDSLGLTEQLQ 194 Bordetella pertussi...
AAR25803 119 -----------------------------------IRFGIARHAQASVAVPddTGAPDVAP---------AAPWLGWLTG 154 Burkholderia multiv...
CAF24115 289 ETTIHVSEEMIPPPITPETtisqfGPYVllAIISGLFLLTGMGIYFLFKSEpvVVNTQENAse---lVQQAIAPFPAVRY 365 Candidatus Protochl...
AAS94349 245 EARP--EGVVVSGLLDDEAQRIRLWDMARNLLYRVQLE---VAVRSDVLHAVKAAFNSRGIYpevtfmpaadttpttppl 319 Desulfovibrio vulga...
CAH19553 166 TWLAd-GSVTLSGHCASSSMMEPLQHFLLRNHIAFRNQ---LVCDDRLIASVSDLLHQHGYH------------------ 223 Yersinia pseudotube...
AAQ60266 170 EWDEr-GVVRLSGLCASSKAIERLRGRMREQGLNFSDE---SLDADTLRRQVRQVLELNGYR------------------ 227 Chromobacterium vio...
AAB06000 120 VAV---ATDDKPAAVAATLEKRPLPLWAKAVYLLLS---------------LLLVMMLGGWL------------------ 163 Erwinia amylovora
AAS20438 128 RSQ---LLIRTTGIIAGLLVGVIGSAWSLTRPPAIA---------------MYQSPGHMASV------------------ 171 Pseudomonas syringa...
AAL20319 166 QWKEd-GSLQLSGYCSSSEQMQKVRATLESWGVMYRDG---VICDDLLVREVQDVLIKMGYP------------------ 223 Salmonella enterica...
Q01245   176 SPKEg-EPWLLTGYIQDNHARLSLQNFLESHGIPFRLE---LRSMEELRQGAEFILQRLGYH------------------ 233 Yersinia enterocoli...
BAC59958 185 EWNAtaHQAVLEGYVEDRTQKLQLLGRIDVLGINYKSD---LRTMEEIRRGVRFILRNLGYH------------------ 243 Vibrio parahaemolyt...
AAC38402 171 VWHG--KNIALYPGGESTTDLTPFFNYLKEKNIFYYNK---IICNNQIISAINDVLTEYGYK------------------ 227 Escherichia coli
CAE42537 195 AAYGrgGVLTVTGWVHDETEFARVARALAQLAPRPAMQ---VSRQDEARALACDVLATFGVR------------------ 253 Bordetella pertussi...
AAR25803 155 GLRRlgSRRLVIALVALWVGVLLGALGYGFVAWSGRLP---WQHESVLARTHRLQRLLHAYP------------------ 213 Burkholderia multiv...
CAF24115 366 SFNKnaGNLLLLGHVSNSADKNQLMYNLQGLKFIKHIDdngIIIDEYVWREINSILSKDPSWr----------------- 428 Candidatus Protochl...
AAS94349 320 saqampkavpgtpdagtglaqspdtattsmagtgtaasgvagtggnggnnsdgksiggmtagtvpagaatlaSAPLATPQ 399 Desulfovibrio vulga...
CAH19553 224 ------------------------------------------------------------------------DIEVRIGD 231 Yersinia pseudotube...
AAQ60266 228 ------------------------------------------------------------------------EVEVSAGA 235 Chromobacterium vio...
AAB06000 164 ------------------------------------------------------------------------LQDSIASP 171 Erwinia amylovora
AAS20438 172 ------------------------------------------------------------------------TAEAPVET 179 Pseudomonas syringa...
AAL20319 224 ------------------------------------------------------------------------HAEVS-SE 230 Salmonella enterica...
Q01245   234 ------------------------------------------------------------------------GIEVSLAP 241 Yersinia enterocoli...
BAC59958 244 ------------------------------------------------------------------------QVKVENGD 251 Vibrio parahaemolyt...
AAC38402 228 ------------------------------------------------------------------------DIIITKGN 235 Escherichia coli
CAE42537 254 ------------------------------------------------------------------------YMARPYGN 261 Bordetella pertussi...
AAR25803 214 --------------------------------------------------------------------------ELAVAP 219 Burkholderia multiv...
CAF24115 429 -------------------------------------------------------------------------GITVHSP 435 Candidatus Protochl...
AAS94349 400 AKAGLRVAGYMRDGVVEAWAFDALREDVPqmPHVTRDLRYASQVAPVLDPLLADAGLKHVQTRY--LSG-VVQLSGDLDA 476 Desulfovibrio vulga...
CAH19553 232 EPGNIVIYGAVQMGDQWLTVQDTLAAVSG--LKGWLVVNAHSGQIQQLVERLRAAGLLGFLSMT--ESNkELAISGVLSS 307 Yersinia pseudotube...
AAQ60266 236 KPDQVVIHGAIQANAAWLRASTQLRAISA--LNGWRVVNDRAELFGRLVDRLSRQRLLDGLSIG--VSGqELLISGQLPP 311 Chromobacterium vio...
AAB06000 172 S-------APPAPGKPLLSSVERTR--------------------QVVTSMLLDRGLDRSVTLS--SDSnSLTLSGSINS 222 Erwinia amylovora
AAS20438 180 SPTPAKIIKPVADKRIRLTSADAVR--------------------HQLGTMLSDR-LLTDVSVE--ETAeGLVLNGDLKE 236 Pseudomonas syringa...
AAL20319 231 GPGSVLIHDDIQMDQQWRKVQPLLADIPG--LLHWQISHSHQSQGDDIISAIIENGLVGLVNVT--PMRrSFVISGVLDE 306 Salmonella enterica...
Q01245   242 QAGWLQLNGEVSEEIQKQKIDSLLQAEVPglLGVENKVRIAGNQRKRLDALLEQFGLDSDFTVN--VKGeLIELRGQVND 319 Yersinia enterocoli...
BAC59958 252 ETGTLLLTGYIDDASKWNQVEQILERDVPglVAWKVELQRAGAYMDTLKELLTNAELLKKVQLV--TSGdRIEVRGELDD 329 Vibrio parahaemolyt...
AAC38402 236 KPGFFLLSGYIPPSPKWSEVENLLLNTPG--VAGWEIHNNSNNKINELASEFKKNKLINYVNIF--KKNdVIIVAGEVSQ 311 Escherichia coli
CAE42537 262 G--RLAISGIASDAHERAAALHAVRMRLPgmTILGRDVRLADEVSAQFAAQLADERLDGVKLSW--HADrLDADPGGLAA 337 Bordetella pertussi...
AAR25803 220 RDDGVIVSGYVADPAARERVAQIVSGIDN---AALGTVYVVSDLVATAQTYFSDTALTVAYLGRgrIELtGTAPRAQLEP 296 Burkholderia multiv...
CAF24115 436 EAGQFILSGYLETRKQAEKLSDYISVNFPylDLLKKQVIVEEDVIGQINVWLQTYNLRGVTVKMg--NGgEITLSGNAPS 513 Candidatus Protochl...
AAS94349 477 AQREALDTVLAQTRTRLQVdIPFEVVQSAPAPDKKQQEAPAPVAGRGFtparqeaaapaqaegpqgidvrsvtLTPLRFV 556 Desulfovibrio vulga...
CAH19553 308 EQQQQLKETLAALSQQQPG-FPSVRYQNIPASDRTDQFLPAKVVSYGG-------------------------NTQSAFV 361 Yersinia pseudotube...
AAQ60266 312 ERARAVAAEAAAFNADGTR-LK-ARFQNIPAAAPAANILPAAIVSVGG-------------------------NANSIYV 364 Chromobacterium vio...
AAB06000 223 EDNQRLERMLANLYQH-----FDVKLPIHNRATTVSMRLPFTIVQIS--------------------------SGPHANI 271 Erwinia amylovora
AAS20438 237 ESLLVYQRMLQRFKDR-----YESPVTVFDNVASTRSALPFVVVQIM--------------------------TGPHAHL 285 Pseudomonas syringa...
AAL20319 307 SHQRILQETLAALKKKDP--ALSLIYQDIAPSHDESKYLPAPVAGFVQ-------------------------SRHGNYL 359 Salmonella enterica...
Q01245   320 EKLSSFNQLQQTFRQEFGN-RPKLELVNVG-GQPQHDELNFEVQAIS--------------------------LGKVPYV 371 Yersinia enterocoli...
BAC59958 330 IETTRFYGVTRDFREQYGE-KPYLVLKSIPKVSKG-TDIDFPFRSVN--------------------------FGQVPYV 381 Vibrio parahaemolyt...
AAC38402 312 QNESKILAIINAMNKNSN---VKILFQNIQPYISA-DIFPGKILRISG-------------------------TMKNPTI 362 Escherichia coli
CAE42537 338 GRMARLRELVAAFNQRN----YDVVRLPATAARATRDHVPFEIRSVV--------------------------SGPQPYL 387 Bordetella pertussi...
AAR25803 297 RIRNYMKDARPALEVVDHVrDAQADAPRTTTTLGGSAGIPEITTVFAG-------------------------DGDQRYI 351 Burkholderia multiv...
CAF24115 514 DKAGEITHLISKIKGLPGVrIVNNYIKADAPEMGIINLSDRYEVTGQS-------------------------KIGNRYT 568 Candidatus Protochl...
AAS94349 557 TTGDGQRIFEGGMLPGGYVVESIS-TTELHLRKDGRSTIYRL 597 Desulfovibrio vulgaris str. Hildenborough
CAH19553 362 RLANGGRLQQGSVLANGYKVVFIG-EQGLTLLKANNLVHIPM 402 Yersinia pseudotuberculosis IP 32953
AAQ60266 365 ELANGMRLQQGGTLPSGYRIYALS-HTALTLIQEQRLVSIPL 405 Chromobacterium violaceum ATCC 12472
AAB06000 272 VTADGQRIFIGDEIDR-LRLVAIN-ADSLEFA-GRENIRVKW 310 Erwinia amylovora
AAS20438 286 VTADGRRIYVGDEVDG-LRLTRID-NQRLQFD-GNRHIEVNW 324 Pseudomonas syringae pv. phaseolicola
AAL20319 360 LLTNKERLRVGALLPNGGEIVHLS-ADVVTIKHYDTLINYPL 400 Salmonella enterica subsp. enterica serovar Typhimurium s...
Q01245   372 VLDNHQRYPEGAILNNGVRILAIR-RDAVIVSKGKREFVIQL 412 Yersinia enterocolitica
BAC59958 382 ILTDNVRYMVGARTPQGYRISSVT-PAGIELVKGGRVITIEL 422 Vibrio parahaemolyticus RIMD 2210633
AAC38402 363 ALDNGTSLGIGNILKGGYVIDAIDpKDGINISRPDEYIHIPL 404 Escherichia coli
CAE42537 388 MLADGSRLLVG-GLRDQYRLTAIE-SGRLVFDGPEPVIVTR- 426 Bordetella pertussis Tohama I
AAR25803 352 ETVDGSRYFEGARLKEGPTVVSIG-PDEVVFERNGQRITMPL 392 Burkholderia multivorans E243
CAF24115 569 IVINGRILSQGDNLDS-MTITSIK-EKVIFLEKDGTKYRIDY 608 Candidatus Protochlamydia amoebophila UWE25
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