6E2S,2HK2,6N0Z,2GS8


Conserved Protein Domain Family
MVD1

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COG3407: MVD1 
Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]
Mevalonate pyrophosphate decarboxylase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Statistics
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PSSM-Id: 442633
Aligned: 134 rows
Threshold Bit Score: 206.197
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6E2S_A        23 NAMLS--GKARAHTNIALIKYWGKANEeyILPMNSSLSLTLDAFYTETTVTFDAHyS----EDV----FILNGIl---QN 89 
WP_010917040  26 MRYGEi-HYGSGYPITGLIKFLGYYDEslKIANFPSISLNTDVSEAYSAFMISKDnG----NDT----AVVEGE----NS 92 
WP_011958963  28 AARVRgvAAALAYPMQGVLKYHGLSDWkyRIAFLPSISLCNDAGHTLTLVEFDPDlP----DDS----ATINGQp---AR 96 
WP_052295718  26 PAYRKi-AFGAGYSEIGIIKSLGYYDStfNILNFPCVSMAADFSRAYAALVLTENiG----EDT----FILNGR----QD 92 
WP_011164107   1 --MKQ--VTVSAPSNIALIKYMGKIEGsgNKPTNGSLSYTLENLRTYVRLTEVDG-A----QDQwk-pLVREDLqkieLS 70 
WP_015691576   1 --MNQ--TCWKSPSNIAIIKYWGKYGR--QLPKNASLSFTLSAAYSQTTLRYSPK-A----KGGiqlrFLFEGQ----EK 65 
WP_014799083  21 IKKGR--ITHQSPSNIALIKYWGKHGV--QLPNNPSLSFTLTNAFTETKLDYQSK-AkkesKTEisleFWFENK----KN 91 
WP_057952058  19 EPEGS--MEWRSPSNIALIKYWGKQGN--QIPMNPSLSMTLKYAFTQTEVKWRPN-Dg---TTQgefdFFLSGQk---VG 87 
WP_079558602   6 QINAS--TEWRSPSNLAIVKYWGKRNV--QEPINPNVSFSLKNSVTITRVTATP-------SEKggftFSLNGA----FN 70 
WP_088820114  38 PHDGEi-SYGEGNPIIGMEKFLGYYDPsmNIAYSPSISMNTDFSVAKAFCRYSKS-G----KDS----IMVDGT----TN 103
6E2S_A        90 EKQTKKVKEFLNLVRQQAD--CTWFAKVESQNFVP---TaaglassasglaalagaCNVAL-G--L--------N---LS 150
WP_010917040  93 PNITKKAMTAINVFKNLYDikGSFHFYLRIKRKYA---GakglgesaavaaaasrsLVSALfE-----------KealKD 158
WP_011958963  97 GRELERVQQSLDAIRAVSG--ATVHARVTSRNVTRgtrFgkglgssasasaalalaAIAALyGeeA--------A---SN 163
WP_052295718  93 EQTMIMARRVVQLLRSIYSirGSFHVYIKVDNKQG---GgcghwesaavaaafarsVARSVfD-----------EsaiED 158
WP_011164107  71 EKGQQRFIKHLQNLKDKWG--IKQSFLIESANNFP---SdcglassassfaaltlaAAEMF-Qq-Inpq---pwG---TD 137
WP_015691576  66 PAFAQRIQGFLESILEELPflDEYALELDSKNSFP---HsagiassassmsalalcLCDMA-Ae-LglgptsdqA---EF 137
WP_014799083  92 KKFEQKIYKFLENLLPTQPflGFVHLKIYSQNSFP---HsagiassassmaalalcLCDLE-Kn-Llntl-qneE---EF 162
WP_057952058  88 PKFEKRVGNLIKEMAKAYPvlNDLYFSITSLNTFP---HstgiassasglsalalsLLSAA-Qr-Atgka-deyP---RF 158
WP_079558602  71 PAFHPKIETFLKQAQHHLPfiRNHHLTIESSNTFP---HssgiassassmsalalcLLSLH-Nl-Sigk--speS---VD 140
WP_088820114 104 EKYLGRMEKALDLFRKENSieGSFQFFLKRERRYK---EakglgesaavasataraLLGCVfG-----------KeavGD 169
6E2S_A       151 AKDLSRLARRGSGSACRSIFGG--FAQWNK--GHSDE---TSFAENIPA-N---NWenELAMLFILINDGEKDVSSRDGM 219
WP_010917040 159 SNFISIVARLASGSGSKSVAGP--LSLWLTapAVSHE---GSFSLNLRK---------EIDDIFLCAVPIRDSVSTAEAH 224
WP_011958963 164 RRLVSCMARLLAGSGCRSAAGG--CSIWLSypGIAHE---ESFAVRLDDaG---QLd-DVRLITVPIDSRI-GLKTEQAH 233
WP_052295718 159 GPFLSKMARLVSGSGAASTTGP--LSVLISwpGYAHD---TSFALGLPM---------PDTGIALCAVPIAADFHRSNIH 224
WP_011164107 138 KKYLSELSRQGSGSSCRSLFTP--WALWQH-----------EYAEPMAFeVk------NLHHMVVIVEDSKKEVSSSEAH 198
WP_015691576 138 WQKASYFARLGSGSACRSLYPM--AASWGE--SKQLKgssNLWASPCGE-LlhdDFk-AVQDTILLVSRAEKSVSSTAGH 211
WP_014799083 163 YQKASYLARLGSGSAARSVYSNipITTWGQ--TENIKdssDLFASPYKL-PihdIFq-KYQDTILIVSAEEKSVSSRAGH 238
WP_057952058 159 LQKASHYARLGSGSACRSIYGP--YAIWGG--GVNTEs-sDEYAIPYKPh---qDFe-IIYDSILIFSEKPKKVGSSAGH 229
WP_079558602 141 LTMASGLSRFGSGSACRSVFGG--WNLWGK--FDEVKessDTYAVPILKnEvspVFq-DLKNVILIINSGSKSVSSSQGH 215
WP_088820114 170 TAFVSRYARLVSGSGSRSAAGG--ISLWMSfpGIANE---ECYAERMEA---------DYKGIKFFTIPEKSLIETISAH 235
6E2S_A       220 KrTVETSSFYQGWLDNVEKDLSQVHEAIKTKDFPRLGEIIEANGLRMHGTTLGA--VPPFTYWSPGSLQAMALVRQARAK 297
WP_010917040 225 N-TVIKSPFYQQWSRLQFDAVYSIIS--RGGYSAQIIENATTNTYLMHSVLIST----GKLLWNQDTLRAMGIVEDMRRI 297
WP_011958963 234 M-DAPASALFRCWMLNRRDEALACIAAARAGDWRTLGQWAELDSMRLHGITMSGslENKLIGWEPENIALFRMCNDLRSG 312
WP_052295718 225 E-VALRSPFYREWATYTRHALLDLLN--SEFDADTIIRTATNSSLMMHATLMSS----RSILWTEKTIDVVSRILEMRSG 297
WP_011164107 199 K-LVTTSPRFTGRPERAELRLKDLSMALQFNDWHIARQIVWDEFIDMHRLFETS--TPSFTYMNDGSKKVLEDCQAFWNK 275
WP_015691576 212 K-LMEGNPFAPLRYQLAEENLGKLLPALQAGDWATFGQIAEEEALMLHALMMTS--RPSYLLMQPNSLALIEKVRDWRQQ 288
WP_014799083 239 A-LMEDNPFAKTRYELAHSNLKKLIIALEKGDTETFIEVVENEAFVLHALMMCS--SPPFILMETGTLTIIKKIQKFRKK 315
WP_057952058 230 K-LMDEHFYRQGRINQVRENSIRLLKALETGDFEMWQEVVEQEALSLHGLMFAS--HEPVLLLEPDTIRFIHDLNAFRAG 306
WP_079558602 216 Q-LMNDHPFREARVEQAFNHTGKLLEILKTGDWNGFIEIAENEALTLHGLMLNS--TPSYTLMEPNSLQAIQLIRRARKD 292
WP_088820114 236 S-AAVQSDFYKNWIFGKYNRIKALLE--NPFSAEDLLSMAEKDMFRLDGILMSS----GFFVHNNSSMSNLGKFFDFKKS 308
6E2S_A       298 -GIPCYFTMDAGPNVKVLVEKKNLEA-LKTFLSEHFS----KEQL------VPA--FAGPGIE-L 347
WP_010917040 298 -GRLIGFSIDTGPSVLVMADREDLIKeFKERYNGECI----DASVpngapdIPS--SFVESAErY 355
WP_011958963 313 -GVPVYCSTDTGPTAVFITHRDYEEA-VVAAIEATGL----GLET------IRG--RIAGPAR-L 362
WP_052295718 298 -GRAVGFSIDAGPSVVLMARNAAELDeARRSIDAECV----DGSItsgepsIPP--EFLRMAReA 355
WP_011164107 276 wQDGPLVTMDAGANVHLLFRHDQKKQ-FAQYREHFEK----DFKV------MAFe-GVKDNVH-- 326
WP_015691576 289 tKLPLYFTLDAGPNLHLLYPKSMQPK-VQPFLQEELLplceNGGH------LAD--ELGCGPEkL 344
WP_014799083 316 tGIPICFTLDAGANVHVLYPKKHKKE-CLNFIEKKLKpfcfEGKY------LKD--NVSYQ---- 367
WP_057952058 307 kGLKVAFTIDAGPNIHLLYADEHREI-IRNFISEWIMdhhlQIQV------LDD--ETGKGAKqL 362
WP_079558602 293 eDLKIGFSMDAGPNLHVLYPESEASK-VEPWIEQNLKplcqNQQM------IYD--SVGDGPInI 348
WP_088820114 309 -NDGVYVTADTGPSLVFFSKDERQLKeLEAYLNPPNVly-gNAAVdf---hMNPnqKDKEQADnY 368
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