1M1J


Conserved Protein Domain Family
Fib_alpha

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pfam08702: Fib_alpha 
Fibrinogen alpha/beta chain family
Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).
Statistics
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PSSM-Id: 462570
Aligned: 65 rows
Threshold Bit Score: 157.704
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1M1J_E        66 DAGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKFSDTSTTMYQYVNMIDNKLVKTQKQRKdNDIILS 145 chicken
OCA48468      50 DKNWPICSDEDWGPKCPSGCRLQGLVDKTDKDFAKRVETIKQKLKDGESSHKSIDLKTKQTYQFLKDNLVQAQqSDGKYN 129
XP_006010728  49 QKEWPLCTTDQWGPKCPSGCRMQGLINNADKEIAERIDKIRKFLAENQNNYKSASLVTRQTHDSLRNTLLGNEdSDRQYS 128
XP_006629594  47 QKEWPICLDEDWGPKCPSGCRIQGLLTKADKDLADKIDKIRKFLDENRNKYRSADQITKTTYDVLREKLVLNTgADNRFQ 126
NP_001181918  45 TKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSgYDNRYM 124
CAF87511      42 KKEWPFCSDDDWGPKCPSGCRIQGLMDKHDFSLLKKIEKIRNLLDQNKAKFRTADQASKQTYDYLKDKLTLDSdNSNKYY 121
XP_013119750  40 EKEWPFCTDVEWGPKCPSGCRIQGLMEKYDHNMLKKIEKIRSLLDQNKAKHRSADTVSKQTYDYLKEKLTTDAgSDNNYF 119
5_pfamImport   1 EKEWPFCTDDQWGPKCPSGCRIQGLMDRFEHGSLKRVEKIRSLLDQHRAKHRSTDLVTKQTYDYLKEKLTSDAgNDNSYY 80 
NP_001258840  49 EKNWPICVDDDWGTKCPSGCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQqLDENYG 128
XP_003221786  49 EKSWPTCSDEEWGIKCPSGCRMQGLIDETDREFNDRINKIKKLLSDNQNSYKKSNILKQELTSFLERNLVDEQeLDNGYG 128
1M1J_E       146 EYNTEMElHYNYIKDNLDNNIpSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIP 209 chicken
OCA48468     130 QVSEDLRkKIEYLKLKVSNQV-ERIKALQKNIRDQVVEMKRLEVDIDIKIRACKGSCAKNTDYK 192
XP_006010728 129 QVVVNLQrRLSILHQRVTAQL-DRIRKLRSLVQDQIYEMQRIEVDIDIKIRACKGSCFKSHLYN 191
XP_006629594 127 NLADQLRqRIIEMKLKIDQQN-SLLIALKSRVRDQVNEVHRIEVDIDIKIRSCKGSCASAHEYT 189
NP_001181918 125 SLAEQLRqRITDIKIKIDRQL-RLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEFS 187
CAF87511     122 ALAQNLRrNINDMKIKIDAQL-RALAALKDRVRDQVSEMQRLEVDIDIKLRSCKGSCERYSAYQ 184
XP_013119750 120 DLAQTLRqRITDMKIKIDRQV-TVLAALRDRVKDQVIEMQRLEVDIDIKLRSCKGSCAGYSEYQ 182
5_pfamImport  81 DLAQGLRqRISDMKIKIDRQL-SILRALKQRVGDQVVEMQRLEVDIDIKLRSCKGSCQSYNTFA 143
NP_001258840 129 HVSTELRrRIVTLKQRVATQV-NRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQ 191
XP_003221786 129 QISDDLRrRLVTLKQRVFNQV-NRIKVLQNTIRNQVGELKRLEVDIDIKIRACKGSCARTYNYH 191
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